Full name : Thompson Charles M
First name : Charles M
Mail : The University of Montana, Department of Chemistry, Missoula, Montana 59812-1006
Zip Code :
City :
Country : USA
Email : cmthomp@selway.um.edu
Phone : 406-243-4643
Fax : 406-243-4227
Website :
Directory :
Comment
Title : [(11)C]Paraoxon: Radiosynthesis, Biodistribution and In Vivo Positron Emission Tomography (PET) Imaging in Rat - Hayes_2023_J.Pharmacol.Exp.Ther__ |
Author(s) : Hayes TR , Chao CK , Blecha JE , Huynh TL , VanBrocklin HF , Zinn KR , Gerdes JM , Thompson CM |
Ref : Journal of Pharmacology & Experimental Therapeutics , : , 2023 |
Abstract : |
PubMedSearch : Hayes_2023_J.Pharmacol.Exp.Ther__ |
PubMedID: 37770203 |
Title : Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats - Hayes_2021_Chem.Res.Toxicol_34_63 |
Author(s) : Hayes TR , Chao CK , Blecha JE , Huynh TL , Zinn KR , Thompson CM , Gerdes JM , VanBrocklin HF |
Ref : Chemical Research in Toxicology , 34 :63 , 2021 |
Abstract : |
PubMedSearch : Hayes_2021_Chem.Res.Toxicol_34_63 |
PubMedID: 33373198 |
Title : Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[(18) F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [(18) F]-VXS - Hayes_2020_Ann.N.Y.Acad.Sci__ |
Author(s) : Hayes TR , Blecha JE , Chao CK , Huynh TL , VanBrocklin HD , Zinn KR , Taylor P , Gerdes JM , Thompson CM |
Ref : Annals of the New York Academy of Sciences , : , 2020 |
Abstract : |
PubMedSearch : Hayes_2020_Ann.N.Y.Acad.Sci__ |
PubMedID: 32436233 |
Title : Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures - Thompson_2020_Neurobiol.Dis_133_104455 |
Author(s) : Thompson CM , Gerdes JM , VanBrocklin HF |
Ref : Neurobiol Dis , 133 :104455 , 2020 |
Abstract : |
PubMedSearch : Thompson_2020_Neurobiol.Dis_133_104455 |
PubMedID: 31022458 |
Title : Inhibition of Acetylcholinesterases by Stereoisomeric Organophosphorus Compounds Containing Both Thioester and p-Nitrophenyl Leaving Groups - Talley_2020_Chem.Res.Toxicol_33_2455 |
Author(s) : Talley TT , Chao CK , Berkman CE , Richardson RJ , Thompson CM |
Ref : Chemical Research in Toxicology , 33 :2455 , 2020 |
Abstract : |
PubMedSearch : Talley_2020_Chem.Res.Toxicol_33_2455 |
PubMedID: 32833441 |
Title : Divergent synthesis of organophosphate [(11)C]VX- and [(11)C]Sarin-surrogates from a common set of starting materials - Hayes_2019_Appl.Radiat.Isot_151_182 |
Author(s) : Hayes TR , Blecha JE , Thompson CM , Gerdes JM , VanBrocklin HF |
Ref : Appl Radiat Isot , 151 :182 , 2019 |
Abstract : |
PubMedSearch : Hayes_2019_Appl.Radiat.Isot_151_182 |
PubMedID: 31202183 |
Title : Comparison of the reactivation rates of acetylcholinesterase modified by structurally different organophosphates using novel pyridinium oximes - Bharate_2019_Environ.Toxicol.Pharmacol_71_103218 |
Author(s) : Bharate SB , Chao CK , Thompson CM |
Ref : Environ Toxicol Pharmacol , 71 :103218 , 2019 |
Abstract : |
PubMedSearch : Bharate_2019_Environ.Toxicol.Pharmacol_71_103218 |
PubMedID: 31302432 |
Title : Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [(11)C]2-Pyridinealdoxime Methiodide ([(11)C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication - Neumann_2018_ACS.Chem.Neurosci_9_3007 |
Author(s) : Neumann KD , Blecha JE , Hayes TR , Huynh T , Chao CK , Guilloteau N , Zinn KR , VanBrocklin HF , Thompson CM , Gerdes JM |
Ref : ACS Chem Neurosci , 9 :3007 , 2018 |
Abstract : |
PubMedSearch : Neumann_2018_ACS.Chem.Neurosci_9_3007 |
PubMedID: 30071719 |
Title : The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE - Chao_2018_Chem.Biol.Interact_291_220 |
Author(s) : Chao CK , Balasubramanian N , Gerdes JM , Thompson CM |
Ref : Chemico-Biological Interactions , 291 :220 , 2018 |
Abstract : |
PubMedSearch : Chao_2018_Chem.Biol.Interact_291_220 |
PubMedID: 29920286 |
Title : Radiosynthesis of O-(1-[(18) F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: A novel PET tracer surrogate of sarin - Hayes_2018_J.Labelled.Comp.Radiopharm_61_1089 |
Author(s) : Hayes TR , Thompson CM , Blecha JE , Gerdes JM , VanBrocklin HF |
Ref : J Labelled Comp Radiopharm , 61 :1089 , 2018 |
Abstract : |
PubMedSearch : Hayes_2018_J.Labelled.Comp.Radiopharm_61_1089 |
PubMedID: 30347484 |
Title : An improved radiosynthesis of O-(2-[18 F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate: A first-in-class cholinesterase PET tracer - Neumann_2017_J.Labelled.Comp.Radiopharm_60_337 |
Author(s) : Neumann KD , Thompson CM , Blecha JE , Gerdes JM , VanBrocklin HF |
Ref : J Labelled Comp Radiopharm , 60 :337 , 2017 |
Abstract : |
PubMedSearch : Neumann_2017_J.Labelled.Comp.Radiopharm_60_337 |
PubMedID: 28406525 |
Title : Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases - Chao_2016_Chem.Res.Toxicol_29_1810 |
Author(s) : Chao CK , Ahmed SK , Gerdes JM , Thompson CM |
Ref : Chemical Research in Toxicology , 29 :1810 , 2016 |
Abstract : |
PubMedSearch : Chao_2016_Chem.Res.Toxicol_29_1810 |
PubMedID: 27551891 |
Title : A Novel Fluorine-18 beta-Fluoroethoxy Organophosphate Positron Emission Tomography Imaging Tracer Targeted to Central Nervous System Acetylcholinesterase - James_2014_ACS.Chem.Neurosci_5_519 |
Author(s) : James SL , Ahmed SK , Murphy S , Braden MR , Belabassi Y , VanBrocklin HF , Thompson CM , Gerdes JM |
Ref : ACS Chem Neurosci , 5 :519 , 2014 |
Abstract : |
PubMedSearch : James_2014_ACS.Chem.Neurosci_5_519 |
PubMedID: 24716794 |
Title : Synthesis and anti-acetylcholinesterase properties of novel beta- and gamma-substituted alkoxy organophosphonates - Kaleem_2013_Bioorg.Med.Chem.Lett_23_2048 |
Author(s) : Kaleem Ahmed S , Belabassi Y , Sankaranarayanan L , Chao CK , Gerdes JM , Thompson CM |
Ref : Bioorganic & Medicinal Chemistry Lett , 23 :2048 , 2013 |
Abstract : |
PubMedSearch : Kaleem_2013_Bioorg.Med.Chem.Lett_23_2048 |
PubMedID: 23453838 |
Title : Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates - Guo_2010_Bioorg.Med.Chem.Lett_20_1194 |
Author(s) : Guo L , Suarez AI , Braden MR , Gerdes JM , Thompson CM |
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1194 , 2010 |
Abstract : |
PubMedSearch : Guo_2010_Bioorg.Med.Chem.Lett_20_1194 |
PubMedID: 20034789 |
Title : Inactivation of acetylcholinesterase by various fluorophores - Guo_2010_J.Enzyme.Inhib.Med.Chem_25_116 |
Author(s) : Guo L , Suarez AI , Thompson CM |
Ref : J Enzyme Inhib Med Chem , 25 :116 , 2010 |
Abstract : |
PubMedSearch : Guo_2010_J.Enzyme.Inhib.Med.Chem_25_116 |
PubMedID: 19842944 |
Title : Paraoxon-induced protein expression changes to SH-SY5Y cells - Prins_2010_Chem.Res.Toxicol_23_1656 |
Author(s) : Prins JM , George KM , Thompson CM |
Ref : Chemical Research in Toxicology , 23 :1656 , 2010 |
Abstract : |
PubMedSearch : Prins_2010_Chem.Res.Toxicol_23_1656 |
PubMedID: 20931991 |
Title : Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase - Bharate_2010_Bioorg.Med.Chem_18_787 |
Author(s) : Bharate SB , Guo L , Reeves TE , Cerasoli DM , Thompson CM |
Ref : Bioorganic & Medicinal Chemistry , 18 :787 , 2010 |
Abstract : |
PubMedSearch : Bharate_2010_Bioorg.Med.Chem_18_787 |
PubMedID: 20005727 |
Title : Organophosphorus pesticides decrease M2 muscarinic receptor function in guinea pig airway nerves via indirect mechanisms - Proskocil_2010_PLoS.One_5_e10562 |
Author(s) : Proskocil BJ , Bruun DA , Thompson CM , Fryer AD , Lein PJ |
Ref : PLoS ONE , 5 :e10562 , 2010 |
Abstract : |
PubMedSearch : Proskocil_2010_PLoS.One_5_e10562 |
PubMedID: 20479945 |
Title : Mass spectrometry identifies multiple organophosphorylated sites on tubulin - Grigoryan_2009_Toxicol.Appl.Pharmacol_240_149 |
Author(s) : Grigoryan H , Schopfer LM , Peeples ES , Duysen EG , Grigoryan M , Thompson CM , Lockridge O |
Ref : Toxicol Appl Pharmacol , 240 :149 , 2009 |
Abstract : |
PubMedSearch : Grigoryan_2009_Toxicol.Appl.Pharmacol_240_149 |
PubMedID: 19632257 |
Title : New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase - Bharate_2009_Bioorg.Med.Chem.Lett_19_5101 |
Author(s) : Bharate SB , Guo L , Reeves TE , Cerasoli DM , Thompson CM |
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :5101 , 2009 |
Abstract : |
PubMedSearch : Bharate_2009_Bioorg.Med.Chem.Lett_19_5101 |
PubMedID: 19640713 |
Title : Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine - Li_2009_Toxicol.Sci_107_144 |
Author(s) : Li B , Schopfer LM , Grigoryan H , Thompson CM , Hinrichs SH , Masson P , Lockridge O |
Ref : Toxicol Sci , 107 :144 , 2009 |
Abstract : |
PubMedSearch : Li_2009_Toxicol.Sci_107_144 |
PubMedID: 18930948 |
Title : Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin - Ding_2008_Chem.Res.Toxicol_21_1787 |
Author(s) : Ding SJ , Carr J , Carlson JE , Tong L , Xue W , Li Y , Schopfer LM , Li B , Nachon F , Asojo OA , Thompson CM , Hinrichs SH , Masson P , Lockridge O |
Ref : Chemical Research in Toxicology , 21 :1787 , 2008 |
Abstract : |
PubMedSearch : Ding_2008_Chem.Res.Toxicol_21_1787 |
PubMedID: 18707141 |
Title : Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents - Grigoryan_2008_Chem.Biol.Interact_175_180 |
Author(s) : Grigoryan H , Schopfer LM , Thompson CM , Terry AV , Masson P , Lockridge O |
Ref : Chemico-Biological Interactions , 175 :180 , 2008 |
Abstract : |
PubMedSearch : Grigoryan_2008_Chem.Biol.Interact_175_180 |
PubMedID: 18502412 |
Title : Analysis and sequencing of the active-site peptide from native and organophosphate-inactivated acetylcholinesterase by electrospray ionization, quadrupole\/time-of-flight (QTOF) mass spectrometry - Spaulding_2006_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_830_105 |
Author(s) : Spaulding RS , George KM , Thompson CM |
Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 830 :105 , 2006 |
Abstract : |
PubMedSearch : Spaulding_2006_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_830_105 |
PubMedID: 16290160 |
Title : Life without acetylcholinesterase: the implications of cholinesterase inhibitor toxicity in AChE-knockout mice - Lockridge_2005_Environ.Toxicol.Pharmacol_19_463 |
Author(s) : Lockridge O , Duysen EG , Voelker T , Thompson CM , Schopfer LM |
Ref : Environ Toxicol Pharmacol , 19 :463 , 2005 |
Abstract : |
PubMedSearch : Lockridge_2005_Environ.Toxicol.Pharmacol_19_463 |
PubMedID: 21783513 |
Title : Identification of organophosphate-reactive proteins by tandem mass spectrometry - |
Author(s) : Li H , Schopfer LM , Spaulding R , Thompson CM , Lockridge O |
Ref : Chemico-Biological Interactions , 157-158 :383 , 2005 |
PubMedID: 16429512 |
Title : Differential localization of acetylcholinesterase in neuronal and non-neuronal cells - Thullbery_2005_J.Cell.Biochem_96_599 |
Author(s) : Thullbery MD , Cox HD , Schule T , Thompson CM , George KM |
Ref : Journal of Cellular Biochemistry , 96 :599 , 2005 |
Abstract : |
PubMedSearch : Thullbery_2005_J.Cell.Biochem_96_599 |
PubMedID: 16052514 |
Title : Characteristic mass spectral fragments of the organophosphorus agent FP-biotin and FP-biotinylated peptides from trypsin and bovine albumin (Tyr410) - Schopfer_2005_Anal.Biochem_345_122 |
Author(s) : Schopfer LM , Champion MM , Tamblyn N , Thompson CM , Lockridge O |
Ref : Analytical Biochemistry , 345 :122 , 2005 |
Abstract : |
PubMedSearch : Schopfer_2005_Anal.Biochem_345_122 |
PubMedID: 16125664 |
Title : Reaction kinetics of biotinylated organophosphorus toxicant, FP-biotin, with human acetylcholinesterase and human butyrylcholinesterase - Schopfer_2005_Chem.Res.Toxicol_18_747 |
Author(s) : Schopfer LM , Voelker T , Bartels CF , Thompson CM , Lockridge O |
Ref : Chemical Research in Toxicology , 18 :747 , 2005 |
Abstract : |
PubMedSearch : Schopfer_2005_Chem.Res.Toxicol_18_747 |
PubMedID: 15833035 |
Title : Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry - Peeples_2005_Toxicol.Sci_83_303 |
Author(s) : Peeples ES , Schopfer LM , Duysen EG , Spaulding R , Voelker T , Thompson CM , Lockridge O |
Ref : Toxicol Sci , 83 :303 , 2005 |
Abstract : |
PubMedSearch : Peeples_2005_Toxicol.Sci_83_303 |
PubMedID: 15525694 |
Title : Stereoselective inactivation of Torpedo californica acetylcholinesterase by isomalathion: inhibitory reactions with (1R)- and (1S)-isomers proceed by different mechanisms - Doorn_2003_Chem.Res.Toxicol_16_958 |
Author(s) : Doorn JA , Thompson CM , Christner RB , Richardson RJ |
Ref : Chemical Research in Toxicology , 16 :958 , 2003 |
Abstract : |
PubMedSearch : Doorn_2003_Chem.Res.Toxicol_16_958 |
PubMedID: 12924923 |
Title : Differentiation between acetylcholinesterase and the organophosphate-inhibited form using antibodies and the correlation of antibody recognition with reactivation mechanism and rate - George_2003_J.Biol.Chem_278_45512 |
Author(s) : George KM , Schule T , Sandoval LE , Jennings LL , Taylor P , Thompson CM |
Ref : Journal of Biological Chemistry , 278 :45512 , 2003 |
Abstract : |
PubMedSearch : George_2003_J.Biol.Chem_278_45512 |
PubMedID: 12933813 |
Title : Examination of cross-antigenicity of acetylcholinesterase and butyrylcholinesterase using anti-acetylcholinesterase antibodies - George_2002_Toxicol.Lett_126_99 |
Author(s) : George KM , Montgomery MA , Sandoval LE , Thompson CM |
Ref : Toxicol Lett , 126 :99 , 2002 |
Abstract : |
PubMedSearch : George_2002_Toxicol.Lett_126_99 |
PubMedID: 11751014 |
Title : Probing the active sites of butyrylcholinesterase and cholesterol esterase with isomalathion: conserved stereoselective inactivation of serine hydrolases structurally related to acetylcholinesterase - Doorn_2001_Chem.Res.Toxicol_14_807 |
Author(s) : Doorn JA , Talley TT , Thompson CM , Richardson RJ |
Ref : Chemical Research in Toxicology , 14 :807 , 2001 |
Abstract : |
PubMedSearch : Doorn_2001_Chem.Res.Toxicol_14_807 |
PubMedID: 11453726 |
Title : Identification of Butyrylcholinesterase Adducts after Inhibition with Isomalathion Using Mass Spectrometry: Difference in Mechanism between (1R)- and (1S)-Stereoisomers - Doorn_2001_Toxicol.Appl.Pharmacol_176_73 |
Author(s) : Doorn JA , Schall M , Gage DA , Talley TT , Thompson CM , Richardson RJ |
Ref : Toxicol Appl Pharmacol , 176 :73 , 2001 |
Abstract : |
PubMedSearch : Doorn_2001_Toxicol.Appl.Pharmacol_176_73 |
PubMedID: 11601883 |
Title : Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group - Doorn_2000_Chem.Res.Toxicol_13_1313 |
Author(s) : Doorn JA , Gage DA , Schall M , Talley TT , Thompson CM , Richardson RJ |
Ref : Chemical Research in Toxicology , 13 :1313 , 2000 |
Abstract : |
PubMedSearch : Doorn_2000_Chem.Res.Toxicol_13_1313 |
PubMedID: 11123973 |
Title : Synthesis of fluorescent probes directed to the active site gorge of acetylcholinesterase - Saltmarsh_2000_Bioorg.Med.Chem.Lett_10_1523 |
Author(s) : Saltmarsh JR , Boyd AE , Rodriguez OP , Radic Z , Taylor P , Thompson CM |
Ref : Bioorganic & Medicinal Chemistry Lett , 10 :1523 , 2000 |
Abstract : |
PubMedSearch : Saltmarsh_2000_Bioorg.Med.Chem.Lett_10_1523 |
PubMedID: 10915041 |
Title : Kinetic Evidence for Different Mechanisms of Acetylcholinesterase Inhibition by (1R)- and (1S)-Stereoisomers of Isomalathion - Jianmongkol_1999_Toxicol.Appl.Pharmacol_155_43 |
Author(s) : Jianmongkol S , Marable BR , Berkman CE , Talley TT , Thompson CM , Richardson RJ |
Ref : Toxicol Appl Pharmacol , 155 :43 , 1999 |
Abstract : |
PubMedSearch : Jianmongkol_1999_Toxicol.Appl.Pharmacol_155_43 |
PubMedID: 10036217 |
Title : Isomalathion Stereoisomers - |
Author(s) : Talley TT , Jianmongkol S , Richardson RJ , Radic Z , Thompson CM |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :531 , 1998 |
PubMedID: |
Title : Inhibition of various cholinesterases with the enantiomers of malaoxon - Rodriguez_1997_Bull.Environ.Contam.Toxicol_58_171 |
Author(s) : Rodriguez OP , Muth GW , Berkman CE , Kim K , Thompson CM |
Ref : Bulletin of Environmental Contamination & Toxicology , 58 :171 , 1997 |
Abstract : |
PubMedSearch : Rodriguez_1997_Bull.Environ.Contam.Toxicol_58_171 |
PubMedID: 8975790 |
Title : Synthesis and 31P chemical shift identification of tripeptide active site models that represent human serum acetylcholinesterase covalently modified at serine by certain organophosphates - Thompson_1996_Chem.Res.Toxicol_9_1325 |
Author(s) : Thompson CM , Suarez AI , Rodriguez OP |
Ref : Chemical Research in Toxicology , 9 :1325 , 1996 |
Abstract : |
PubMedSearch : Thompson_1996_Chem.Res.Toxicol_9_1325 |
PubMedID: 8951236 |
Title : Relative potencies of the four stereoisomers of isomalathion for inhibition of hen brain acetylcholinesterase and neurotoxic esterase in vitro - Jianmongkol_1996_Toxicol.Appl.Pharmacol_139_342 |
Author(s) : Jianmongkol S , Berkman CE , Thompson CM , Richardson RJ |
Ref : Toxicology & Applied Pharmacology , 139 :342 , 1996 |
Abstract : |
PubMedSearch : Jianmongkol_1996_Toxicol.Appl.Pharmacol_139_342 |
PubMedID: 8806851 |
Title : Synthesis, absolute configuration, and analysis of malathion, malaoxon, and isomalathion enantiomers [published erratum appears in Chem Res Toxicol 1994 Mar-Apr\;7(2):275] - Berkman_1993_Chem.Res.Toxicol_6_718 |
Author(s) : Berkman CE , Thompson CM , Perrin SR |
Ref : Chemical Research in Toxicology , 6 :718 , 1993 |
Abstract : |
PubMedSearch : Berkman_1993_Chem.Res.Toxicol_6_718 |
PubMedID: 8292751 |
Title : Interaction of acetylcholinesterase with the enantiomers of malaoxon and isomalathion - Berkman_1993_Chem.Res.Toxicol_6_724 |
Author(s) : Berkman CE , Quinn DA , Thompson CM |
Ref : Chemical Research in Toxicology , 6 :724 , 1993 |
Abstract : |
PubMedSearch : Berkman_1993_Chem.Res.Toxicol_6_724 |
PubMedID: 8292752 |
Title : Kinetics of the postinhibitory reactions of acetylcholinesterase poisoned by chiral isomalathion: a surprising nonreactivation induced by the RP stereoisomers - Berkman_1993_Chem.Res.Toxicol_6_28 |
Author(s) : Berkman CE , Ryu S , Quinn DA , Thompson CM |
Ref : Chemical Research in Toxicology , 6 :28 , 1993 |
Abstract : |
PubMedSearch : Berkman_1993_Chem.Res.Toxicol_6_28 |
PubMedID: 8448346 |