| Title : Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists - Perez-Medrano_2011_Bioorg.Med.Chem.Lett_21_3297 |
| Author(s) : Perez-Medrano A , Donnelly-Roberts D , Florjancic AS , Nelson DW , Li T , Namovic MT , Peddi S , Faltynek CR , Jarvis MF , Carroll WA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :3297 , 2011 |
| Abstract : |
| PubMedSearch : Perez-Medrano_2011_Bioorg.Med.Chem.Lett_21_3297 |
| PubMedID: 21536435 |
| Title : [3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors - Donnelly-Roberts_2009_Neuropharmacol_56_223 |
| Author(s) : Donnelly-Roberts D , Namovic MT , Surber B , Vaidyanathan SX , Perez-Medrano A , Wang Y , Carroll WA , Jarvis MF |
| Ref : Neuropharmacology , 56 :223 , 2009 |
| Abstract : |
| PubMedSearch : Donnelly-Roberts_2009_Neuropharmacol_56_223 |
| PubMedID: 18602931 |
| Title : Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain - Perez-Medrano_2009_J.Med.Chem_52_3366 |
| Author(s) : Perez-Medrano A , Donnelly-Roberts D , Honore P , Hsieh GC , Namovic MT , Peddi S , Shuai Q , Wang Y , Faltynek CR , Jarvis MF , Carroll WA |
| Ref : Journal of Medicinal Chemistry , 52 :3366 , 2009 |
| Abstract : |
| PubMedSearch : Perez-Medrano_2009_J.Med.Chem_52_3366 |
| PubMedID: 19397270 |
| Title : Selective P2X(7) receptor antagonists for chronic inflammation and pain - Carroll_2009_Purinergic.Signal_5_63 |
| Author(s) : Carroll WA , Donnelly-Roberts D , Jarvis MF |
| Ref : Purinergic Signal , 5 :63 , 2009 |
| Abstract : |
| PubMedSearch : Carroll_2009_Purinergic.Signal_5_63 |
| PubMedID: 18568426 |
| Title : Synthesis and in vitro activity of N'-cyano-4-(2-phenylacetyl)-N-o-tolylpiperazine-1-carboximidamide P2X7 antagonists - Morytko_2008_Bioorg.Med.Chem.Lett_18_2093 |
| Author(s) : Morytko MJ , Betschmann P , Woller K , Ericsson A , Chen H , Donnelly-Roberts D , Namovic MT , Jarvis MF , Carroll WA , Rafferty P |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :2093 , 2008 |
| Abstract : |
| PubMedSearch : Morytko_2008_Bioorg.Med.Chem.Lett_18_2093 |
| PubMedID: 18272365 |
| Title : Structure-activity relationship studies on N'-aryl carbohydrazide P2X7 antagonists - Nelson_2008_J.Med.Chem_51_3030 |
| Author(s) : Nelson DW , Sarris K , Kalvin DM , Namovic MT , Grayson G , Donnelly-Roberts D , Harris R , Honore P , Jarvis MF , Faltynek CR , Carroll WA |
| Ref : Journal of Medicinal Chemistry , 51 :3030 , 2008 |
| Abstract : |
| PubMedSearch : Nelson_2008_J.Med.Chem_51_3030 |
| PubMedID: 18438986 |
| Title : Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists - Florjancic_2008_Bioorg.Med.Chem.Lett_18_2089 |
| Author(s) : Florjancic AS , Peddi S , Perez-Medrano A , Li B , Namovic MT , Grayson G , Donnelly-Roberts D , Jarvis MF , Carroll WA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :2089 , 2008 |
| Abstract : |
| PubMedSearch : Florjancic_2008_Bioorg.Med.Chem.Lett_18_2089 |
| PubMedID: 18272366 |
| Title : Novel and potent 3-(2,3-dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 antagonists - Carroll_2007_Bioorg.Med.Chem.Lett_17_4044 |
| Author(s) : Carroll WA , Kalvin DM , Perez Medrano A , Florjancic AS , Wang Y , Donnelly-Roberts D , Namovic MT , Grayson G , Honore P , Jarvis MF |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :4044 , 2007 |
| Abstract : |
| PubMedSearch : Carroll_2007_Bioorg.Med.Chem.Lett_17_4044 |
| PubMedID: 17482819 |
| Title : P2X7-related modulation of pathological nociception in rats - McGaraughty_2007_Neurosci_146_1817 |
| Author(s) : McGaraughty S , Chu KL , Namovic MT , Donnelly-Roberts D , Harris RR , Zhang XF , Shieh CC , Wismer CT , Zhu CZ , Gauvin DM , Fabiyi AC , Honore P , Gregg RJ , Kort ME , Nelson DW , Carroll WA , Marsh K , Faltynek CR , Jarvis MF |
| Ref : Neuroscience , 146 :1817 , 2007 |
| Abstract : |
| PubMedSearch : McGaraughty_2007_Neurosci_146_1817 |
| PubMedID: 17478048 |
| Title : Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists - Nelson_2006_J.Med.Chem_49_3659 |
| Author(s) : Nelson DW , Gregg RJ , Kort ME , Perez-Medrano A , Voight EA , Wang Y , Grayson G , Namovic MT , Donnelly-Roberts D , Niforatos W , Honore P , Jarvis MF , Faltynek CR , Carroll WA |
| Ref : Journal of Medicinal Chemistry , 49 :3659 , 2006 |
| Abstract : |
| PubMedSearch : Nelson_2006_J.Med.Chem_49_3659 |
| PubMedID: 16759108 |