| Title : Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists - Perez-Medrano_2011_Bioorg.Med.Chem.Lett_21_3297 |
| Author(s) : Perez-Medrano A , Donnelly-Roberts D , Florjancic AS , Nelson DW , Li T , Namovic MT , Peddi S , Faltynek CR , Jarvis MF , Carroll WA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :3297 , 2011 |
| Abstract : |
| PubMedSearch : Perez-Medrano_2011_Bioorg.Med.Chem.Lett_21_3297 |
| PubMedID: 21536435 |
| Title : [3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors - Donnelly-Roberts_2009_Neuropharmacol_56_223 |
| Author(s) : Donnelly-Roberts D , Namovic MT , Surber B , Vaidyanathan SX , Perez-Medrano A , Wang Y , Carroll WA , Jarvis MF |
| Ref : Neuropharmacology , 56 :223 , 2009 |
| Abstract : |
| PubMedSearch : Donnelly-Roberts_2009_Neuropharmacol_56_223 |
| PubMedID: 18602931 |
| Title : Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain - Perez-Medrano_2009_J.Med.Chem_52_3366 |
| Author(s) : Perez-Medrano A , Donnelly-Roberts D , Honore P , Hsieh GC , Namovic MT , Peddi S , Shuai Q , Wang Y , Faltynek CR , Jarvis MF , Carroll WA |
| Ref : Journal of Medicinal Chemistry , 52 :3366 , 2009 |
| Abstract : |
| PubMedSearch : Perez-Medrano_2009_J.Med.Chem_52_3366 |
| PubMedID: 19397270 |
| Title : The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1alphabeta knockout mice - Honore_2009_Behav.Brain.Res_204_77 |
| Author(s) : Honore P , Donnelly-Roberts D , Namovic M , Zhong C , Wade C , Chandran P , Zhu C , Carroll W , Perez-Medrano A , Iwakura Y , Jarvis MF |
| Ref : Behavioural Brain Research , 204 :77 , 2009 |
| Abstract : |
| PubMedSearch : Honore_2009_Behav.Brain.Res_204_77 |
| PubMedID: 19464323 |
| Title : Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists - Florjancic_2008_Bioorg.Med.Chem.Lett_18_2089 |
| Author(s) : Florjancic AS , Peddi S , Perez-Medrano A , Li B , Namovic MT , Grayson G , Donnelly-Roberts D , Jarvis MF , Carroll WA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :2089 , 2008 |
| Abstract : |
| PubMedSearch : Florjancic_2008_Bioorg.Med.Chem.Lett_18_2089 |
| PubMedID: 18272366 |
| Title : Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists - Nelson_2006_J.Med.Chem_49_3659 |
| Author(s) : Nelson DW , Gregg RJ , Kort ME , Perez-Medrano A , Voight EA , Wang Y , Grayson G , Namovic MT , Donnelly-Roberts D , Niforatos W , Honore P , Jarvis MF , Faltynek CR , Carroll WA |
| Ref : Journal of Medicinal Chemistry , 49 :3659 , 2006 |
| Abstract : |
| PubMedSearch : Nelson_2006_J.Med.Chem_49_3659 |
| PubMedID: 16759108 |