Castro RN

Title : Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studies - Silva_2024_Eur.J.Med.Chem_281_117030

Author(s) : Silva Sousa GL , Nadur NF , de Almeida Peixoto Ferreira L , da Silva Honorio T , Simon A , Cabral LM , Mora Santos ML , Andrade B , de Lima EV , Clarke JR , Castro RN , Olimpio de Moura R , Kummerle AE

Ref : Eur Journal of Medicinal Chemistry , 281 :117030 , 2024

Abstract :

PubMedSearch : Silva_2024_Eur.J.Med.Chem_281_117030

PubMedID: 39531933

Title : Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant - de Souza_2019_J.Enzyme.Inhib.Med.Chem_34_631

Author(s) : de Souza GA , da Silva SJ , Del Cistia CN , Pitasse-Santos P , Pires LO , Passos YM , Cordeiro Y , Cardoso CM , Castro RN , Sant'Anna CMR , Kummerle AE

Ref : J Enzyme Inhib Med Chem , 34 :631 , 2019

Abstract :

PubMedSearch : de Souza_2019_J.Enzyme.Inhib.Med.Chem_34_631

PubMedID: 30727776

Castro RN

References (2)

1. Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studies - Silva_2024_Eur.J.Med.Chem_281_117030

2. Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant - de Souza_2019_J.Enzyme.Inhib.Med.Chem_34_631