Deacon CF

References (28)

Title : Dipeptidyl peptidase 4 inhibitors in the treatment of type 2 diabetes mellitus - Deacon_2020_Nat.Rev.Endocrinol_16_642
Author(s) : Deacon CF
Ref : Nat Rev Endocrinol , 16 :642 , 2020
PubMedID: 32929230

Title : Why is it so difficult to measure glucagon-like peptide-1 in a mouse? - Windelov_2017_Diabetologia_60_2066
Author(s) : Windelov JA , Wewer Albrechtsen NJ , Kuhre RE , Jepsen SL , Hornburg D , Pedersen J , Jensen EP , Galsgaard KD , Winther-Sorensen M , Orgaard A , Deacon CF , Mann M , Kissow H , Hartmann B , Holst JJ
Ref : Diabetologia , 60 :2066 , 2017
PubMedID: 28669086

Title : Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas - Deacon_2016_Diabetes.Obes.Metab_18_333
Author(s) : Deacon CF , Lebovitz HE
Ref : Diabetes Obes Metab , 18 :333 , 2016
PubMedID: 26597596

Title : Inhibition of DPP-4 with Vildagliptin Improved Insulin Secretion in Response to Oral as well as Isoglycemic Intravenous Glucose without Numerically Changing the Incretin Effect in Patients with Type 2 Diabetes - Vardarli_2011_J.Clin.Endocrinol.Metab_96_945
Author(s) : Vardarli I , Nauck MA , Kothe LD , Deacon CF , Holst JJ , Schweizer A , Foley JE
Ref : J Clinical Endocrinology Metab , 96 :945 , 2011
PubMedID: 21239518

Title : Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down? - Nauck_2011_Diabetologia_54_10
Author(s) : Nauck MA , Vardarli I , Deacon CF , Holst JJ , Meier JJ
Ref : Diabetologia , 54 :10 , 2011
PubMedID: 20871975

Title : Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review - Deacon_2011_Diabetes.Obes.Metab_13_7
Author(s) : Deacon CF
Ref : Diabetes Obes Metab , 13 :7 , 2011
PubMedID: 21114598

Title : The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose - Bock_2010_Clin.Endocrinol.(Oxf)_73_189
Author(s) : Bock G , Dalla Man C , Micheletto F , Basu R , Giesler PD , Laugen J , Deacon CF , Holst JJ , Toffolo G , Cobelli C , Rizza RA , Vella A
Ref : Clinical Endocrinology (Oxf) , 73 :189 , 2010
PubMedID: 20039889

Title : Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men - Carr_2010_J.Clin.Endocrinol.Metab_95_872
Author(s) : Carr RD , Larsen MO , Jelic K , Lindgren O , Vikman J , Holst JJ , Deacon CF , Ahren B
Ref : J Clinical Endocrinology Metab , 95 :872 , 2010
PubMedID: 20008019

Title : Immunoassays for the incretin hormones GIP and GLP-1 - Deacon_2009_Best.Pract.Res.Clin.Endocrinol.Metab_23_425
Author(s) : Deacon CF , Holst JJ
Ref : Best Pract Res Clinical Endocrinology Metab , 23 :425 , 2009
PubMedID: 19748060

Title : Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes - Deacon_2009_Adv.Ther_26_488
Author(s) : Deacon CF , Holst JJ
Ref : Adv Ther , 26 :488 , 2009
PubMedID: 19444391

Title : DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes - Deacon_2008_Front.Biosci_13_1780
Author(s) : Deacon CF , Carr RD , Holst JJ
Ref : Front Biosci , 13 :1780 , 2008
PubMedID: 17981667

Title : Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials - Madsbad_2008_Curr.Opin.Clin.Nutr.Metab.Care_11_491
Author(s) : Madsbad S , Krarup T , Deacon CF , Holst JJ
Ref : Curr Opin Clin Nutr Metab Care , 11 :491 , 2008
PubMedID: 18542012

Title : Glucagon-like peptide-1, glucose homeostasis and diabetes - Holst_2008_Trends.Mol.Med_14_161
Author(s) : Holst JJ , Deacon CF , Vilsboll T , Krarup T , Madsbad S
Ref : Trends Mol Med , 14 :161 , 2008
PubMedID: 18353723

Title : Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes - Azuma_2008_J.Clin.Endocrinol.Metab_93_459
Author(s) : Azuma K , Radikova Z , Mancino J , Toledo FG , Thomas E , Kangani C , Dalla Man C , Cobelli C , Holst JJ , Deacon CF , He Y , Ligueros-Saylan M , Serra D , Foley JE , Kelley DE
Ref : J Clinical Endocrinology Metab , 93 :459 , 2008
PubMedID: 18042650

Title : The effect of dipeptidyl peptidase-4 inhibition on gastric volume, satiation and enteroendocrine secretion in type 2 diabetes: a double-blind, placebo-controlled crossover study - Vella_2008_Clin.Endocrinol.(Oxf)_69_737
Author(s) : Vella A , Bock G , Giesler PD , Burton DB , Serra DB , Saylan ML , Deacon CF , Foley JE , Rizza RA , Camilleri M
Ref : Clinical Endocrinology (Oxf) , 69 :737 , 2008
PubMedID: 18331607

Title : Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes - Deacon_2008_Curr.Opin.Investig.Drugs_9_402
Author(s) : Deacon CF
Ref : Curr Opin Investig Drugs , 9 :402 , 2008
PubMedID: 18393107

Title : Dipeptidyl peptidase 4 inhibition with sitagliptin: a new therapy for type 2 diabetes - Deacon_2007_Expert.Opin.Investig.Drugs_16_533
Author(s) : Deacon CF
Ref : Expert Opin Investig Drugs , 16 :533 , 2007
PubMedID: 17371200

Title : The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients - Balas_2007_J.Clin.Endocrinol.Metab_92_1249
Author(s) : Balas B , Baig MR , Watson C , Dunning BE , Ligueros-Saylan M , Wang Y , He YL , Darland C , Holst JJ , Deacon CF , Cusi K , Mari A , Foley JE , DeFronzo RA
Ref : J Clinical Endocrinology Metab , 92 :1249 , 2007
PubMedID: 17244786

Title : Incretin-based treatment of type 2 diabetes: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors - Deacon_2007_Diabetes.Obes.Metab_9 Suppl 1_23
Author(s) : Deacon CF
Ref : Diabetes Obes Metab , 9 Suppl 1 :23 , 2007
PubMedID: 17877544

Title : Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes - Herman_2006_J.Clin.Endocrinol.Metab_91_4612
Author(s) : Herman GA , Bergman A , Stevens C , Kotey P , Yi B , Zhao P , Dietrich B , Golor G , Schrodter A , Keymeulen B , Lasseter KC , Kipnes MS , Snyder K , Hilliard D , Tanen M , Cilissen C , De Smet M , De Lepeleire I , Van Dyck K , Wang AQ , Zeng W , Davies MJ , Tanaka W , Holst JJ , Deacon CF , Gottesdiener KM , Wagner JA
Ref : J Clinical Endocrinology Metab , 91 :4612 , 2006
PubMedID: 16912128

Title : Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes - Deacon_2006_Int.J.Biochem.Cell.Biol_38_831
Author(s) : Deacon CF , Holst JJ
Ref : International Journal of Biochemistryistry & Cell Biology , 38 :831 , 2006
PubMedID: 16242377

Title : The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans - Meier_2006_Am.J.Physiol.Endocrinol.Metab_290_E1118
Author(s) : Meier JJ , Gethmann A , Nauck MA , Gotze O , Schmitz F , Deacon CF , Gallwitz B , Schmidt WE , Holst JJ
Ref : American Journal of Physiology Endocrinol Metab , 290 :E1118 , 2006
PubMedID: 16403774

Title : Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake - Ryskjaer_2006_Eur.J.Endocrinol_155_485
Author(s) : Ryskjaer J , Deacon CF , Carr RD , Krarup T , Madsbad S , Holst J , Vilsboll T
Ref : European Journal of Endocrinology , 155 :485 , 2006
PubMedID: 16914604

Title : The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes - Zander_2006_Diabetologia_49_369
Author(s) : Zander M , Madsbad S , Deacon CF , Holst JJ
Ref : Diabetologia , 49 :369 , 2006
PubMedID: 16385384

Title : MK-431 (Merck) - Deacon_2005_Curr.Opin.Investig.Drugs_6_419
Author(s) : Deacon CF
Ref : Curr Opin Investig Drugs , 6 :419 , 2005
PubMedID: 15898349

Title : Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig - Plamboeck_2005_Diabetologia_48_1882
Author(s) : Plamboeck A , Holst JJ , Carr RD , Deacon CF
Ref : Diabetologia , 48 :1882 , 2005
PubMedID: 16025254

Title : Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes - Mari_2005_J.Clin.Endocrinol.Metab_90_4888
Author(s) : Mari A , Sallas WM , He YL , Watson C , Ligueros-Saylan M , Dunning BE , Deacon CF , Holst JJ , Foley JE
Ref : J Clinical Endocrinology Metab , 90 :4888 , 2005
PubMedID: 15886245

Title : Circulation and degradation of GIP and GLP-1 - Deacon_2004_Horm.Metab.Res_36_761
Author(s) : Deacon CF
Ref : Hormone & Metabolic Research , 36 :761 , 2004
PubMedID: 15655705