Eglen RM

General

Full name : Eglen Richard M

First name : Richard

Mail : Corning Life Sciences , Tewksbury, Massachusetts

Zip Code :

City :

Country : USA

Email : eglenrm@corning.com

Phone :

Fax :

Website :

Directory :

References (53)

Title : Overview of muscarinic receptor subtypes - Eglen_2012_Handb.Exp.Pharmacol_208_3
Author(s) : Eglen RM
Ref : Handbook of Experimental Pharmacology , :3 , 2012
Abstract :
PubMedSearch : Eglen_2012_Handb.Exp.Pharmacol_208_3
PubMedID: 22222692

Title : Poster: Pharmacological characterisation of muscarinic receptors in human isolated ciliary smooth muscle -
Author(s) : Choppin A , Eglen RM
Ref : Life Sciences , 68 :2633 , 2001
PubMedID:

Title : Poster: Pharmacological characterisation of muscarinic receptors in mouse urinary bladder smooth muscle -
Author(s) : Eglen RM , Choppin A
Ref : Life Sciences , 68 :2634 , 2001
PubMedID:

Title : Muscarinic receptors and gastrointestinal tract smooth muscle function - Eglen_2001_Life.Sci_68(22-23)_2573
Author(s) : Eglen RM
Ref : Life Sciences , 68 :2573 , 2001
Abstract :
PubMedSearch : Eglen_2001_Life.Sci_68(22-23)_2573
PubMedID: 11392628

Title : Poster: In vivo evidence for a functional role of muscarinic M2 receptors in rat urinary bladder -
Author(s) : Cefalu JS , Shetty SG , Silva R , Watson N , Eglen RM
Ref : Life Sciences , 68 :2630 , 2001
PubMedID:

Title : Poster: Muscarinic M2 receptor function in rata tria and urinary bladder smooth muscle in vitro -
Author(s) : Bringas A , Groke G , Eglen RM , Choppin A
Ref : Life Sciences , 68 :2630 , 2001
PubMedID:

Title : Poster: Muscarinic receptors in rat uterus: Effect of ovariectomy -
Author(s) : Choppin A , Watson N , Hegde SS , Eglen RM
Ref : Life Sciences , 64 :582 , 1999
PubMedID:

Title : Poster: Similarities in antagonist affinity profiles of muscarinic M3 and M5 cholinoceptors: Pharmacological difficulties associated with identifying a functional M5 receptor -
Author(s) : Watson N , Choppin A , Hegde SS , Eglen RM
Ref : Life Sciences , 64 :557 , 1999
PubMedID:

Title : Muscarinic receptor subtypes modulating smooth muscle contractility in the urinary bladder - Hegde_1999_Life.Sci_64(6-7)_419
Author(s) : Hegde SS , Eglen RM
Ref : Life Sciences , 64 :419 , 1999
Abstract :
PubMedSearch : Hegde_1999_Life.Sci_64(6-7)_419
PubMedID: 10069505

Title : Poster: Functional pharmacological characterization of the muscarinic cholinoceptor-mediated inhibition of adenylyl cyclase in primary cultured human bladder detrusor smooth muscle cells -
Author(s) : Daniels DV , Meloy TD , Loury DN , Watson N , Hegde SS , Ford AP , Eglen RM
Ref : Life Sciences , 64 :590 , 1999
PubMedID:

Title : Poster: Complex M2\/M3 receptor antagonist profile in human colon bioassay -
Author(s) : Eglen RM , Welsh NJ , Shankley NP , Black JW
Ref : Life Sciences , 64 :592 , 1999
PubMedID:

Title : Poster: Ionic strength of assay buffers influences antagonist binding affinity estimates at muscarinic M1-M5 cholinoceptors -
Author(s) : Loury DN , Hegde SS , Bonhaus DW , Eglen RM
Ref : Life Sciences , 64 :557 , 1999
PubMedID:

Title : Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea-pig isolated uterus - Boxall_1998_Br.J.Pharmacol_124_1615
Author(s) : Boxall DK , Ford AP , Choppin A , Nahorski SR , Challiss RA , Eglen RM
Ref : British Journal of Pharmacology , 124 :1615 , 1998
Abstract :
PubMedSearch : Boxall_1998_Br.J.Pharmacol_124_1615
PubMedID: 9756376

Title : Poster: Muscarinic M2 receptors modulate relaxant responses to isoproterenol in rat urinary bladder -
Author(s) : Choppin A , Eglen RM , Hegde SS
Ref : Life Sciences , 60 :1193 , 1997
PubMedID:

Title : Characterization of the interaction between muscarinic M2 receptors and beta-adrenoceptor subtypes in guinea-pig isolated ileum - Reddy_1995_Br.J.Pharmacol_114_49
Author(s) : Reddy H , Watson N , Ford AP , Eglen RM
Ref : British Journal of Pharmacology , 114 :49 , 1995
Abstract :
PubMedSearch : Reddy_1995_Br.J.Pharmacol_114_49
PubMedID: 7712028

Title : Characterization of muscarinic receptor and beta-adrenoceptor interactions in guinea-pig oesophageal muscularis mucosae - Watson_1995_Eur.J.Pharmacol_294_779
Author(s) : Watson N , Reddy H , Eglen RM
Ref : European Journal of Pharmacology , 294 :779 , 1995
Abstract :
PubMedSearch : Watson_1995_Eur.J.Pharmacol_294_779
PubMedID: 8750745

Title : Pharmacological characterization of the muscarinic receptors mediating contraction of canine saphenous vein - Watson_1995_J.Auton.Pharmacol_15_437
Author(s) : Watson N , Reddy H , Eglen RM
Ref : J Auton Pharmacol , 15 :437 , 1995
Abstract :
PubMedSearch : Watson_1995_J.Auton.Pharmacol_15_437
PubMedID: 8920160

Title : Role of muscarinic M2 and M3 receptors in guinea-pig trachea: effects of receptor alkylation - Watson_1995_Eur.J.Pharmacol_278_195
Author(s) : Watson N , Reddy H , Eglen RM
Ref : European Journal of Pharmacology , 278 :195 , 1995
Abstract :
PubMedSearch : Watson_1995_Eur.J.Pharmacol_278_195
PubMedID: 7589155

Title : Characterization of the interaction of zamifenacin at muscarinic receptors in vitro - Watson_1995_Eur.J.Pharmacol_285_135
Author(s) : Watson N , Reddy H , Stefanich E , Eglen RM
Ref : European Journal of Pharmacology , 285 :135 , 1995
Abstract :
PubMedSearch : Watson_1995_Eur.J.Pharmacol_285_135
PubMedID: 8566131

Title : The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro - Wong_1995_Br.J.Pharmacol_114_851
Author(s) : Wong EH , Clark R , Leung E , Loury D , Bonhaus DW , Jakeman L , Parnes H , Whiting RL , Eglen RM
Ref : British Journal of Pharmacology , 114 :851 , 1995
Abstract :
PubMedSearch : Wong_1995_Br.J.Pharmacol_114_851
PubMedID: 7773546

Title : M3 muscarinic receptors on murine HSDM1C1 cells: further functional, regulatory, and receptor binding studies - Sharif_1995_Neurochem.Res_20_61
Author(s) : Sharif NA , To ZP , Wong KH , Delmendo RE , Whiting RL , Eglen RM
Ref : Neurochem Res , 20 :61 , 1995
Abstract :
PubMedSearch : Sharif_1995_Neurochem.Res_20_61
PubMedID: 7739761

Title : Selective inactivation of muscarinic receptor subtypes - Eglen_1994_Int.J.Biochem_26_1357
Author(s) : Eglen RM , Reddy H , Watson N
Ref : International Journal of Biochemistry , 26 :1357 , 1994
Abstract :
PubMedSearch : Eglen_1994_Int.J.Biochem_26_1357
PubMedID: 7890115

Title : Muscarinic acetylcholine receptor subtypes in smooth muscle - Eglen_1994_Trends.Pharmacol.Sci_15_114
Author(s) : Eglen RM , Reddy H , Watson N , Challiss RA
Ref : Trends in Pharmacological Sciences , 15 :114 , 1994
Abstract :
PubMedSearch : Eglen_1994_Trends.Pharmacol.Sci_15_114
PubMedID: 8016895

Title : Poster: Muscarinic receptor protection studies in isolated, functional preparations -
Author(s) : Eglen RM , Harris GC
Ref : Life Sciences , 52(5-6) :571 , 1993
PubMedID:

Title : Poster: Characterization of muscarinic receptors in guinea-pig seminal vesicle -
Author(s) : Eglen RM , Harris GC , Faurot GF , Waterbury LD , Levine WB , Whiting RL
Ref : Life Sciences , 52(5-6) :572 , 1993
PubMedID:

Title : Acute desensitization of muscarinic receptors in the isolated guinea-pig ileal longitudinal muscle - Eglen_1992_J.Auton.Pharmacol_12_137
Author(s) : Eglen RM , Adham N , Whiting RL
Ref : J Auton Pharmacol , 12 :137 , 1992
Abstract :
PubMedSearch : Eglen_1992_J.Auton.Pharmacol_12_137
PubMedID: 1629233

Title : Characterization of the interaction of the cervane alkaloid, imperialine, at muscarinic receptors in vitro - Eglen_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_346_144
Author(s) : Eglen RM , Harris GC , Cox H , Sullivan AO , Stefanich E , Whiting RL
Ref : Naunyn Schmiedebergs Arch Pharmacol , 346 :144 , 1992
Abstract :
PubMedSearch : Eglen_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_346_144
PubMedID: 1448179

Title : The action of (+\/-)L-660,863 [(+\/-)3-(3-amino-1,2,4-oxadiazole-5-yl)-quinuclidine] at muscarinic receptor subtypes in vitro - Eglen_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_345_375
Author(s) : Eglen RM , Harris GC , Ford AP , Wong EH , Pfister JR , Whiting RL
Ref : Naunyn Schmiedebergs Arch Pharmacol , 345 :375 , 1992
Abstract :
PubMedSearch : Eglen_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_345_375
PubMedID: 1620240

Title : Analysis of muscarinic cholinoceptors mediating phosphoinositide hydrolysis in guinea pig cardiac muscle - Ford_1992_Eur.J.Pharmacol_225_105
Author(s) : Ford AP , Eglen RM , Whiting RL
Ref : European Journal of Pharmacology , 225 :105 , 1992
Abstract :
PubMedSearch : Ford_1992_Eur.J.Pharmacol_225_105
PubMedID: 1551411

Title : Characterization of muscarinic receptors mediating release of epithelial derived relaxant factor (EpDRF) in guinea-pig isolated trachea - Eglen_1991_Naunyn.Schmiedebergs.Arch.Pharmacol_344_29
Author(s) : Eglen RM , Harris GC , Taylor M , Pfister JR , Whiting RL
Ref : Naunyn Schmiedebergs Arch Pharmacol , 344 :29 , 1991
Abstract :
PubMedSearch : Eglen_1991_Naunyn.Schmiedebergs.Arch.Pharmacol_344_29
PubMedID: 1775190

Title : Desensitization and functional antagonism by beta-adrenoceptor and muscarinic receptor agonists, respectively: a comparison with receptor alkylation for calculation of apparent agonist affinity - Eglen_1991_Br.J.Pharmacol_103_1951
Author(s) : Eglen RM , Montgomery WW , Whiting RL
Ref : British Journal of Pharmacology , 103 :1951 , 1991
Abstract :
PubMedSearch : Eglen_1991_Br.J.Pharmacol_103_1951
PubMedID: 1680517

Title : 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum - Craig_1990_Naunyn.Schmiedebergs.Arch.Pharmacol_342_9
Author(s) : Craig DA , Eglen RM , Walsh LK , Perkins LA , Whiting RL , Clarke DE
Ref : Naunyn Schmiedebergs Arch Pharmacol , 342 :9 , 1990
Abstract :
PubMedSearch : Craig_1990_Naunyn.Schmiedebergs.Arch.Pharmacol_342_9
PubMedID: 2402303

Title : Interaction of p-F-HHSiD (p-Fluoro-hexahydrosila-difenidol) at muscarinic receptors in guinea-pig trachea - Eglen_1990_Naunyn.Schmiedebergs.Arch.Pharmacol_342_394
Author(s) : Eglen RM , Cornett CM , Whiting RL
Ref : Naunyn Schmiedebergs Arch Pharmacol , 342 :394 , 1990
Abstract :
PubMedSearch : Eglen_1990_Naunyn.Schmiedebergs.Arch.Pharmacol_342_394
PubMedID: 2255333

Title : The interaction of parafluorohexahydrosiladiphenidol at muscarinic receptors in vitro - Eglen_1990_Br.J.Pharmacol_99_637
Author(s) : Eglen RM , Michel AD , Montgomery WW , Kunysz EA , Machado CA , Whiting RL
Ref : British Journal of Pharmacology , 99 :637 , 1990
Abstract :
PubMedSearch : Eglen_1990_Br.J.Pharmacol_99_637
PubMedID: 2361166

Title : Heterogeneity of vascular muscarinic receptors - Eglen_1990_J.Auton.Pharmacol_10_233
Author(s) : Eglen RM , Whiting RL
Ref : J Auton Pharmacol , 10 :233 , 1990
Abstract :
PubMedSearch : Eglen_1990_J.Auton.Pharmacol_10_233
PubMedID: 2229100

Title : The interaction of hexamethonium with muscarinic receptor subtypes in vitro - Eglen_1989_Br.J.Pharmacol_98_499
Author(s) : Eglen RM , Michel AD , Cornett CM , Kunysz EA , Whiting RL
Ref : British Journal of Pharmacology , 98 :499 , 1989
Abstract :
PubMedSearch : Eglen_1989_Br.J.Pharmacol_98_499
PubMedID: 2819331

Title : The pharmacological properties of the peptide, endothelin - Eglen_1989_Br.J.Pharmacol_97_1297
Author(s) : Eglen RM , Michel AD , Sharif NA , Swank SR , Whiting RL
Ref : British Journal of Pharmacology , 97 :1297 , 1989
Abstract :
PubMedSearch : Eglen_1989_Br.J.Pharmacol_97_1297
PubMedID: 2551446

Title : Characterization of the muscarinic receptor subtype mediating contractions of the guinea-pig uterus - Eglen_1989_Br.J.Pharmacol_96_497
Author(s) : Eglen RM , Michel AD , Whiting RL
Ref : British Journal of Pharmacology , 96 :497 , 1989
Abstract :
PubMedSearch : Eglen_1989_Br.J.Pharmacol_96_497
PubMedID: 2497919

Title : Problems associated with the application of the Cheng-Prusoff relationship to estimate atropine affinity constants using functional tissue responses - Eglen_1989_Life.Sci_44_81
Author(s) : Eglen RM , Whiting RL
Ref : Life Sciences , 44 :81 , 1989
Abstract :
PubMedSearch : Eglen_1989_Life.Sci_44_81
PubMedID: 2913438

Title : Poster: Interaction of p-fluorohexahydrosiladifenidol (pFHHSiD) at muscarinic receptor subtypes in vitro -
Author(s) : Whiting RL , Eglen RM , Montgomery W , Machado CA
Ref : Trends in Pharmacological Sciences , Suppl :106 , 1989
PubMedID:

Title : Poster: Characterization of muscarinic receptors mediating responses in canin femoral vein and artery in vitro -
Author(s) : Eglen RM , Montgomery WW , Machado CA
Ref : Trends in Pharmacological Sciences , Suppl :107 , 1989
PubMedID:

Title : Differential effects of pertussis toxin on muscarinic responses in isolated atria and smooth muscle - Eglen_1988_J.Auton.Pharmacol_8_29
Author(s) : Eglen RM , Huff MM , Montgomery WW , Whiting RL
Ref : J Auton Pharmacol , 8 :29 , 1988
Abstract :
PubMedSearch : Eglen_1988_J.Auton.Pharmacol_8_29
PubMedID: 3392052

Title : Negative and positive inotropic responses to muscarinic agonists in guinea pig and rat atria in vitro - Eglen_1988_J.Pharmacol.Exp.Ther_247_911
Author(s) : Eglen RM , Montgomery WW , Whiting RL
Ref : Journal of Pharmacology & Experimental Therapeutics , 247 :911 , 1988
Abstract :
PubMedSearch : Eglen_1988_J.Pharmacol.Exp.Ther_247_911
PubMedID: 2849676

Title : Comparison of the muscarinic receptors of the guinea-pig oesophageal muscularis mucosae and trachea in vitro - Eglen_1988_J.Auton.Pharmacol_8_181
Author(s) : Eglen RM , Whiting RL
Ref : J Auton Pharmacol , 8 :181 , 1988
Abstract :
PubMedSearch : Eglen_1988_J.Auton.Pharmacol_8_181
PubMedID: 3198662

Title : The interaction of methoctramine and himbacine at atrial, smooth muscle and endothelial muscarinic receptors in vitro - Eglen_1988_Br.J.Pharmacol_95_1031
Author(s) : Eglen RM , Montgomery WW , Dainty IA , Dubuque LK , Whiting RL
Ref : British Journal of Pharmacology , 95 :1031 , 1988
Abstract :
PubMedSearch : Eglen_1988_Br.J.Pharmacol_95_1031
PubMedID: 3219478

Title : Differential effects of pertussis toxin and lithium on muscarinic responses in the atria and ileum: evidence for receptor heterogeneity - Eglen_1987_Br.J.Pharmacol_91_6
Author(s) : Eglen RM , Huff MM , Montgomery WW , Whiting RL
Ref : British Journal of Pharmacology , 91 :6 , 1987
Abstract :
PubMedSearch : Eglen_1987_Br.J.Pharmacol_91_6
PubMedID: 3594083

Title : Muscarinic activity of McN-A-343 and its value in muscarinic receptor classification - Eglen_1987_Br.J.Pharmacol_90_693
Author(s) : Eglen RM , Kenny BA , Michel AD , Whiting RL
Ref : British Journal of Pharmacology , 90 :693 , 1987
Abstract :
PubMedSearch : Eglen_1987_Br.J.Pharmacol_90_693
PubMedID: 2437988

Title : Competitive and non-competitive antagonism exhibited by 'selective' antagonists at atrial and ileal muscarinic receptor subtypes - Eglen_1987_Br.J.Pharmacol_90_701
Author(s) : Eglen RM , Whiting RL
Ref : British Journal of Pharmacology , 90 :701 , 1987
Abstract :
PubMedSearch : Eglen_1987_Br.J.Pharmacol_90_701
PubMedID: 3580704

Title : Estimation of apparent agonist affinity constants using desensitization of the ileal muscarinic receptor - Eglen_1987_J.Pharmacol.Exp.Ther_240_404
Author(s) : Eglen RM , Whiting RL
Ref : Journal of Pharmacology & Experimental Therapeutics , 240 :404 , 1987
Abstract :
PubMedSearch : Eglen_1987_J.Pharmacol.Exp.Ther_240_404
PubMedID: 3806405

Title : Poster: McN-A-343: a selective agonist at M1 receptors in terms of potency but not affinity -
Author(s) : Eglen RM , Michel AD , Whiting RL
Ref : Trends in Pharmacological Sciences , Suppl :91 , 1986
PubMedID:

Title : Muscarinic receptor subtypes: a critique of the current classification and a proposal for a working nomenclature -
Author(s) : Eglen RM , Whiting RL
Ref : J Auton Pharmacol , 6 :323 , 1986
PubMedID: 3546321

Title : Action of agonists and antagonists at muscarinic receptors present on ileum and atria in vitro - Clague_1985_Br.J.Pharmacol_86_163
Author(s) : Clague RU , Eglen RM , Strachan AC , Whiting RL
Ref : British Journal of Pharmacology , 86 :163 , 1985
Abstract :
PubMedSearch : Clague_1985_Br.J.Pharmacol_86_163
PubMedID: 3876860

Title : Determination of the muscarinic receptor subtype mediating vasodilatation - Eglen_1985_Br.J.Pharmacol_84_3
Author(s) : Eglen RM , Whiting RL
Ref : British Journal of Pharmacology , 84 :3 , 1985
Abstract :
PubMedSearch : Eglen_1985_Br.J.Pharmacol_84_3
PubMedID: 3838488