Full name : Frangez Robert
First name : Robert
Mail : Institute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana
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City :
Country : Slovenia
Email : robert.frangez@vf.uni-lj.si
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Comment
Title : Structural Insights into the Marine Alkaloid Discorhabdin G as a Scaffold towards New Acetylcholinesterase Inhibitors - Defant_2024_Mar.Drugs_22_ |
Author(s) : Defant A , Carloni G , Innocenti N , Trobec T , Frangez R , Sepcic K , Mancini I |
Ref : Mar Drugs , 22 : , 2024 |
Abstract : |
PubMedSearch : Defant_2024_Mar.Drugs_22_ |
PubMedID: 38667790 |
Title : New insights into the effects of organometallic ruthenium complexes on nicotinic acetylcholine receptors - Trobec_2024_Chem.Biol.Interact_402_111213 |
Author(s) : Trobec T , Lamassiaude N , Benoit E , Zuzek MC , Sepcic K , Kladnik J , Turel I , Araoz R , Frangez R |
Ref : Chemico-Biological Interactions , 402 :111213 , 2024 |
Abstract : |
PubMedSearch : Trobec_2024_Chem.Biol.Interact_402_111213 |
PubMedID: 39209017 |
Title : Novel Organoruthenium(II) Complex C1 Selectively Inhibits Butyrylcholinesterase without Side Effects on Neuromuscular Transmission - Trobec_2023_Int.J.Mol.Sci_24_ |
Author(s) : Trobec T , Zuzek MC , Sepcic K , Kladnik J , Turel I , Frangez R |
Ref : Int J Mol Sci , 24 : , 2023 |
Abstract : |
PubMedSearch : Trobec_2023_Int.J.Mol.Sci_24_ |
PubMedID: 36769002 |
Title : Development of potent cholinesterase inhibitors based on a marine pharmacophore - Elumalai_2022_Org.Biomol.Chem__ |
Author(s) : Elumalai V , Trobec T , Grundner M , Labriere C , Frangez R , Sepcic K , Hansen JH , Svenson J |
Ref : Org Biomol Chem , : , 2022 |
Abstract : |
PubMedSearch : Elumalai_2022_Org.Biomol.Chem__ |
PubMedID: 35796650 |
Title : Fine Tuning of Cholinesterase and Glutathione-S-Transferase Activities by Organoruthenium(II) Complexes - Trobec_2021_Biomedicines_9_ |
Author(s) : Trobec T , Sepcic K , uzek MC , Kladnik J , Podjed N , Cardoso Pascoa C , Turel I , Frangez R |
Ref : Biomedicines , 9 : , 2021 |
Abstract : |
PubMedSearch : Trobec_2021_Biomedicines_9_ |
PubMedID: 34572429 |
Title : Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum - Safa_2021_J.Nat.Prod__ |
Author(s) : Safa N , Trobec T , Holland DC , Slazak B , Jacobsson E , Hawkes JA , Frangez R , Sepcic K , Goransson U , Moodie LWK , Robertson LP |
Ref : Journal of Natural Products , : , 2021 |
Abstract : |
PubMedSearch : Safa_2021_J.Nat.Prod__ |
PubMedID: 34910498 |
Title : Structural and functional characterization of an organometallic ruthenium complex as a potential myorelaxant drug - Trobec_2020_Biomed.Pharmacother_127_110161 |
Author(s) : Trobec T , Zuzek MC , Sepcic K , Kladnik J , Kljun J , Turel I , Benoit E , Frangez R |
Ref : Biomed Pharmacother , 127 :110161 , 2020 |
Abstract : |
PubMedSearch : Trobec_2020_Biomed.Pharmacother_127_110161 |
PubMedID: 32380389 |
Title : Organoruthenium Prodrugs as a New Class of Cholinesterase and Glutathione-S-Transferase Inhibitors - Ristovski_2018_ChemMedChem_13_2166 |
Author(s) : Ristovski S , Uzelac M , Kljun J , Lipec T , Ursic M , Zemljic Jokhadar S , Zuzek MC , Trobec T , Frangez R , Sepcic K , Turel I |
Ref : ChemMedChem , 13 :2166 , 2018 |
Abstract : |
PubMedSearch : Ristovski_2018_ChemMedChem_13_2166 |
PubMedID: 30126080 |
Title : Natural polymeric 3-alkylpyridinium salt affects vertebrate skeletal muscle contractility by preferentially blocking neuromuscular transmission - Zuzek_2017_Toxicol.Lett_281_95 |
Author(s) : Zuzek MC , Grandic M , Benoit E , Frangez R |
Ref : Toxicol Lett , 281 :95 , 2017 |
Abstract : |
PubMedSearch : Zuzek_2017_Toxicol.Lett_281_95 |
PubMedID: 28939337 |
Title : Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors - Botic_2017_Eur.J.Med.Chem_136_294 |
Author(s) : Botic T , Defant A , Zanini P , Zuzek MC , Frangez R , Janussen D , Kersken D , Knez Z , Mancini I , Sepcic K |
Ref : Eur Journal of Medicinal Chemistry , 136 :294 , 2017 |
Abstract : |
PubMedSearch : Botic_2017_Eur.J.Med.Chem_136_294 |
PubMedID: 28505534 |
Title : Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission - Moodie_2016_Org.Biomol.Chem_14_11220 |
Author(s) : Moodie LW , Zuzek MC , Frangez R , Andersen JH , Hansen E , Olsen EK , Cergolj M , Sepcic K , Hansen KO , Svenson J |
Ref : Org Biomol Chem , 14 :11220 , 2016 |
Abstract : |
PubMedSearch : Moodie_2016_Org.Biomol.Chem_14_11220 |
PubMedID: 27841892 |
Title : Pathophysiological Effects of Synthetic Derivatives of Polymeric Alkylpyridinium Salts from the Marine Sponge, Reniera sarai - Grandic_2014_Mar.Drugs_12_2408 |
Author(s) : Grandic M , Frangez R |
Ref : Mar Drugs , 12 :2408 , 2014 |
Abstract : |
PubMedSearch : Grandic_2014_Mar.Drugs_12_2408 |
PubMedID: 24796301 |
Title : Binding and permeabilization of lipid bilayers by natural and synthetic 3-alkylpyridinium polymers - Grandic_2012_Bioorg.Med.Chem_20_1659 |
Author(s) : Grandic M , Zovko A , Frangez R , Turk T , Sepcic K |
Ref : Bioorganic & Medicinal Chemistry , 20 :1659 , 2012 |
Abstract : |
PubMedSearch : Grandic_2012_Bioorg.Med.Chem_20_1659 |
PubMedID: 22325153 |
Title : The non-competitive acetylcholinesterase inhibitor APS12-2 is a potent antagonist of skeletal muscle nicotinic acetylcholine receptors - Grandic_2012_Toxicol.Appl.Pharmacol_265_221 |
Author(s) : Grandic M , Araoz R , Molgo J , Turk T , Sepcic K , Benoit E , Frangez R |
Ref : Toxicol Appl Pharmacol , 265 :221 , 2012 |
Abstract : |
PubMedSearch : Grandic_2012_Toxicol.Appl.Pharmacol_265_221 |
PubMedID: 23046821 |
Title : In vivo toxic and lethal cardiovascular effects of a synthetic polymeric 1,3-dodecylpyridinium salt in rodents - Grandic_2011_Toxicol.Appl.Pharmacol_255_86 |
Author(s) : Grandic M , Sepcic K , Turk T , Juntes P , Frangez R |
Ref : Toxicol Appl Pharmacol , 255 :86 , 2011 |
Abstract : |
PubMedSearch : Grandic_2011_Toxicol.Appl.Pharmacol_255_86 |
PubMedID: 21704644 |
Title : Mechanisms of toxicity of 3-alkylpyridinium polymers from marine sponge Reniera sarai - Turk_2007_Mar.Drugs_5_157 |
Author(s) : Turk T , Frangez R , Sepcic K |
Ref : Mar Drugs , 5 :157 , 2007 |
Abstract : |
PubMedSearch : Turk_2007_Mar.Drugs_5_157 |
PubMedID: 18463730 |