Sepcic K

General

Full name : Sepcic Kristina

First name : Kristina

Mail : Department of Biology, Biotechnical Faculty, University of Ljubljana, Vecna pot 111, 1000 Ljubljana

Zip Code :

City :

Country : Slovenia

Email : kristina.sepcic@bf.uni-lj.si

Phone : (386-61) 1233388

Fax : (386-61) 273390

Website :

Directory :

References (46)

Title : Structural Insights into the Marine Alkaloid Discorhabdin G as a Scaffold towards New Acetylcholinesterase Inhibitors - Defant_2024_Mar.Drugs_22_
Author(s) : Defant A , Carloni G , Innocenti N , Trobec T , Frangez R , Sepcic K , Mancini I
Ref : Mar Drugs , 22 : , 2024
PubMedID: 38667790

Title : Novel Organoruthenium(II) Complex C1 Selectively Inhibits Butyrylcholinesterase without Side Effects on Neuromuscular Transmission - Trobec_2023_Int.J.Mol.Sci_24_
Author(s) : Trobec T , Zuzek MC , Sepcic K , Kladnik J , Turel I , Frangez R
Ref : Int J Mol Sci , 24 : , 2023
PubMedID: 36769002

Title : Development of potent cholinesterase inhibitors based on a marine pharmacophore - Elumalai_2022_Org.Biomol.Chem__
Author(s) : Elumalai V , Trobec T , Grundner M , Labriere C , Frangez R , Sepcic K , Hansen JH , Svenson J
Ref : Org Biomol Chem , : , 2022
PubMedID: 35796650

Title : Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum - Safa_2021_J.Nat.Prod__
Author(s) : Safa N , Trobec T , Holland DC , Slazak B , Jacobsson E , Hawkes JA , Frangez R , Sepcic K , Goransson U , Moodie LWK , Robertson LP
Ref : Journal of Natural Products , : , 2021
PubMedID: 34910498

Title : Fine Tuning of Cholinesterase and Glutathione-S-Transferase Activities by Organoruthenium(II) Complexes - Trobec_2021_Biomedicines_9_
Author(s) : Trobec T , Sepcic K , uzek MC , Kladnik J , Podjed N , Cardoso Pascoa C , Turel I , Frangez R
Ref : Biomedicines , 9 : , 2021
PubMedID: 34572429

Title : Structural and functional characterization of an organometallic ruthenium complex as a potential myorelaxant drug - Trobec_2020_Biomed.Pharmacother_127_110161
Author(s) : Trobec T , Zuzek MC , Sepcic K , Kladnik J , Kljun J , Turel I , Benoit E , Frangez R
Ref : Biomed Pharmacother , 127 :110161 , 2020
PubMedID: 32380389

Title : Structural Isomerism and Enhanced Lipophilicity of Pyrithione Ligands of Organoruthenium(II) Complexes Increase Inhibition on AChE and BuChE - Kladnik_2020_Int.J.Mol.Sci_21_
Author(s) : Kladnik J , Ristovski S , Kljun J , Defant A , Mancini I , Sepcic K , Turel I
Ref : Int J Mol Sci , 21 : , 2020
PubMedID: 32781544

Title : First evidence of cholinesterase-like activity in Basidiomycota - Sepcic_2019_PLoS.One_14_e0216077
Author(s) : Sepcic K , Sabotic J , R AO , Drobne D , Jemec Kokalj A
Ref : PLoS ONE , 14 :e0216077 , 2019
PubMedID: 31039204

Title : Natural cholinesterase inhibitors from marine organisms - Moodie_2019_Nat.Prod.Rep_36_1053
Author(s) : Moodie LWK , Sepcic K , Turk T , Frange ZR , Svenson J
Ref : Nat Prod Rep , 36 :1053 , 2019
PubMedID: 30924818

Title : Organoruthenium Prodrugs as a New Class of Cholinesterase and Glutathione-S-Transferase Inhibitors - Ristovski_2018_ChemMedChem_13_2166
Author(s) : Ristovski S , Uzelac M , Kljun J , Lipec T , Ursic M , Zemljic Jokhadar S , Zuzek MC , Trobec T , Frangez R , Sepcic K , Turel I
Ref : ChemMedChem , 13 :2166 , 2018
PubMedID: 30126080

Title : Feeding Preference and Sub-chronic Effects of ZnO Nanomaterials in Honey Bees (Apis mellifera carnica) - Glavan_2017_Arch.Environ.Contam.Toxicol_72_471
Author(s) : Glavan G , Milivojevic T , Bozic J , Sepcic K , Drobne D
Ref : Archives of Environmental Contamination & Toxicology , 72 :471 , 2017
PubMedID: 28271210

Title : Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus - de Vries_2017_Genome.Biol_18_28
Author(s) : de Vries RP , Riley R , Wiebenga A , Aguilar-Osorio G , Amillis S , Uchima CA , Anderluh G , Asadollahi M , Askin M , Barry K , Battaglia E , Bayram O , Benocci T , Braus-Stromeyer SA , Caldana C , Canovas D , Cerqueira GC , Chen F , Chen W , Choi C , Clum A , Dos Santos RA , Damasio AR , Diallinas G , Emri T , Fekete E , Flipphi M , Freyberg S , Gallo A , Gournas C , Habgood R , Hainaut M , Harispe ML , Henrissat B , Hilden KS , Hope R , Hossain A , Karabika E , Karaffa L , Karanyi Z , Krasevec N , Kuo A , Kusch H , LaButti K , Lagendijk EL , Lapidus A , Levasseur A , Lindquist E , Lipzen A , Logrieco AF , Maccabe A , Makela MR , Malavazi I , Melin P , Meyer V , Mielnichuk N , Miskei M , Molnar AP , Mule G , Ngan CY , Orejas M , Orosz E , Ouedraogo JP , Overkamp KM , Park HS , Perrone G , Piumi F , Punt PJ , Ram AF , Ramon A , Rauscher S , Record E , Riano-Pachon DM , Robert V , Rohrig J , Ruller R , Salamov A , Salih NS , Samson RA , Sandor E , Sanguinetti M , Schutze T , Sepcic K , Shelest E , Sherlock G , Sophianopoulou V , Squina FM , Sun H , Susca A , Todd RB , Tsang A , Unkles SE , van de Wiele N , van Rossen-Uffink D , Oliveira JV , Vesth TC , Visser J , Yu JH , Zhou M , Andersen MR , Archer DB , Baker SE , Benoit I , Brakhage AA , Braus GH , Fischer R , Frisvad JC , Goldman GH , Houbraken J , Oakley B , Pocsi I , Scazzocchio C , Seiboth B , vanKuyk PA , Wortman J , Dyer PS , Grigoriev IV
Ref : Genome Biol , 18 :28 , 2017
PubMedID: 28196534
Gene_locus related to this paper: asptu-a0a1l9nhd0 , aspve-a0a1l9pxx8 , aspve-a0a1l9q4m3 , aspwe-a0a1l9s133 , 9euro-a0a1l9t3v9 , aspwe-a0a1l9rcx6 , aspna-g3y5a6 , aspgl-a0a1l9v4d3 , 9euro-a0a1l9sa36 , aspsb-a0a319eji6 , aspve-a0a1l9px96 , 9euro-a0a1l9tay1 , aspgl-a0a1l9vbc0 , aspc5-a0a1r3rh65 , 9euro-a0a2v5i956 , aspwe-a0a1l9rpp6 , aspna-g3xpw9 , aspve-a0a1l9plv1 , 9euro-a0a1l9tk47 , aspve-a0a1l9pde9 , aspve-a0a1l9pz72 , aspwe-a0a1l9rde6 , 9euro-a0a1l9tdb5 , aspkw-g7xq95 , aspbc-a0a1l9u6h4 , aspbc-a0a1l9u2l4 , asptc-a0a1l9mx83 , aspgl-a0a1l9ve90 , aspve-a0a1l9pvz9 , 9euro-a0a1l9tdh3 , aspc5-a0a1r3rmn9 , aspwe-a0a1l9rlq2 , asptc-a0a1l9nby7 , aspng-a0a100i8t9 , aspc5-a0a1r3rem6 , aspbc-a0a1l9uy89 , aspa1-anee , aspa1-aneh , aspa1-acrc , aspbc-alba , aspa1-acui

Title : Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors - Botic_2017_Eur.J.Med.Chem_136_294
Author(s) : Botic T , Defant A , Zanini P , Zuzek MC , Frangez R , Janussen D , Kersken D , Knez Z , Mancini I , Sepcic K
Ref : Eur Journal of Medicinal Chemistry , 136 :294 , 2017
PubMedID: 28505534

Title : Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs - Olsen_2016_Org.Biomol.Chem_14_1629
Author(s) : Olsen EK , Hansen E , L WKM , Isaksson J , Sepcic K , Cergolj M , Svenson J , Andersen JH
Ref : Org Biomol Chem , 14 :1629 , 2016
PubMedID: 26695619

Title : Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission - Moodie_2016_Org.Biomol.Chem_14_11220
Author(s) : Moodie LW , Zuzek MC , Frangez R , Andersen JH , Hansen E , Olsen EK , Cergolj M , Sepcic K , Hansen KO , Svenson J
Ref : Org Biomol Chem , 14 :11220 , 2016
PubMedID: 27841892

Title : Differences in tolerance to anthropogenic stress between invasive and native bivalves - Bielen_2015_Sci.Total.Environ_543_449
Author(s) : Bielen A , Bosnjak I , Sepcic K , Jaklic M , Cvitanic M , Lusic J , Lajtner J , Simcic T , Hudina S
Ref : Sci Total Environ , 543 :449 , 2015
PubMedID: 26599145

Title : High surface adsorption properties of carbon-based nanomaterials are responsible for mortality, swimming inhibition, and biochemical responses in Artemia salina larvae - Mesaric_2015_Aquat.Toxicol_163_121
Author(s) : Mesaric T , Gambardella C , Milivojevic T , Faimali M , Drobne D , Falugi C , Makovec D , Jemec A , Sepcic K
Ref : Aquat Toxicol , 163 :121 , 2015
PubMedID: 25889088

Title : Sperm exposure to carbon-based nanomaterials causes abnormalities in early development of purple sea urchin (Paracentrotus lividus) - Mesaric_2015_Aquat.Toxicol_163_158
Author(s) : Mesaric T , Sepcic K , Drobne D , Makovec D , Faimali M , Morgana S , Falugi C , Gambardella C
Ref : Aquat Toxicol , 163 :158 , 2015
PubMedID: 25897690

Title : Isolation and Synthesis of Pulmonarins A and B, Acetylcholinesterase Inhibitors from the Colonial Ascidian Synoicum pulmonaria - Tadesse_2014_J.Nat.Prod_77_364
Author(s) : Tadesse M , Svenson J , Sepcic K , Trembleau L , Engqvist M , Andersen JH , Jaspars M , Stensvag K , Haug T
Ref : Journal of Natural Products , 77 :364 , 2014
PubMedID: 24547899

Title : Effects of selected metal oxide nanoparticles on Artemia salina larvae: evaluation of mortality and behavioural and biochemical responses - Gambardella_2014_Environ.Monit.Assess_186_4249
Author(s) : Gambardella C , Mesaric T , Milivojevic T , Sepcic K , Gallus L , Carbone S , Ferrando S , Faimali M
Ref : Environ Monit Assess , 186 :4249 , 2014
PubMedID: 24590232

Title : Antifouling activity of synthetic alkylpyridinium polymers using the barnacle model - Piazza_2014_Mar.Drugs_12_1959
Author(s) : Piazza V , Dragic I , Sepcic K , Faimali M , Garaventa F , Turk T , Berne S
Ref : Mar Drugs , 12 :1959 , 2014
PubMedID: 24699112

Title : Neurotoxic potential of ingested ZnO nanomaterials on bees - Milivojevic_2014_Chemosphere_120C_547
Author(s) : Milivojevic T , Glavan G , Bozic J , Sepcic K , Mesaric T , Drobne D
Ref : Chemosphere , 120C :547 , 2014
PubMedID: 25305659

Title : Binding and permeabilization of lipid bilayers by natural and synthetic 3-alkylpyridinium polymers - Grandic_2012_Bioorg.Med.Chem_20_1659
Author(s) : Grandic M , Zovko A , Frangez R , Turk T , Sepcic K
Ref : Bioorganic & Medicinal Chemistry , 20 :1659 , 2012
PubMedID: 22325153

Title : The non-competitive acetylcholinesterase inhibitor APS12-2 is a potent antagonist of skeletal muscle nicotinic acetylcholine receptors - Grandic_2012_Toxicol.Appl.Pharmacol_265_221
Author(s) : Grandic M , Araoz R , Molgo J , Turk T , Sepcic K , Benoit E , Frangez R
Ref : Toxicol Appl Pharmacol , 265 :221 , 2012
PubMedID: 23046821

Title : In vivo toxic and lethal cardiovascular effects of a synthetic polymeric 1,3-dodecylpyridinium salt in rodents - Grandic_2011_Toxicol.Appl.Pharmacol_255_86
Author(s) : Grandic M , Sepcic K , Turk T , Juntes P , Frangez R
Ref : Toxicol Appl Pharmacol , 255 :86 , 2011
PubMedID: 21704644

Title : Parazoanthoxanthin A blocks Torpedo nicotinic acetylcholine receptors - Rozman_2010_Chem.Biol.Interact_187_384
Author(s) : Rozman KB , Araoz R , Sepcic K , Molgo J , Suput D
Ref : Chemico-Biological Interactions , 187 :384 , 2010
PubMedID: 20230806

Title : Biochemical biomarkers in environmental studies--lessons learnt from enzymes catalase, glutathione S-transferase and cholinesterase in two crustacean species - Jemec_2010_Environ.Sci.Pollut.Res.Int_17_571
Author(s) : Jemec A , Drobne D , Tisler T , Sepcic K
Ref : Environ Sci Pollut Res Int , 17 :571 , 2010
PubMedID: 19259718

Title : Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins - Houssen_2010_J.Chem.Biol_3_113
Author(s) : Houssen WE , Lu Z , Edrada-Ebel R , Chatzi C , Tucker SJ , Sepcic K , Turk T , Zovko A , Shen S , Mancini I , Scott RH , Jaspars M
Ref : J Chemical Biology , 3 :113 , 2010
PubMedID: 21326630

Title : Influence of polymeric 3-alkylpyridinium salts from the marine sponge Reniera sarai on the growth of algae and wood decay fungi - Elersek_2008_Biofouling_24_137
Author(s) : Elersek T , Kosi G , Turk T , Pohleven F , Sepcic K
Ref : Biofouling , 24 :137 , 2008
PubMedID: 18274962

Title : Biochemical biomarkers in chronically metal-stressed daphnids - Jemec_2008_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_147_61
Author(s) : Jemec A , Tisler T , Drobne D , Sepcic K , Jamnik P , Ros M
Ref : Comparative Biochemistry & Physiology C Toxicol Pharmacol , 147 :61 , 2008
PubMedID: 17728189

Title : The applicability of acetylcholinesterase and glutathione S-transferase in Daphnia magna toxicity test - Jemec_2007_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_144_303
Author(s) : Jemec A , Drobne D , Tisler T , Trebse P , Ros M , Sepcic K
Ref : Comparative Biochemistry & Physiology C Toxicol Pharmacol , 144 :303 , 2007
PubMedID: 17126609

Title : Mechanisms of toxicity of 3-alkylpyridinium polymers from marine sponge Reniera sarai - Turk_2007_Mar.Drugs_5_157
Author(s) : Turk T , Frangez R , Sepcic K
Ref : Mar Drugs , 5 :157 , 2007
PubMedID: 18463730

Title : Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors - Paleari_2006_Int.J.Oncol_29_1381
Author(s) : Paleari L , Trombino S , Falugi C , Gallus L , Carlone S , Angelini C , Sepcic K , Turk T , Faimali M , Noonan DM , Albini A
Ref : Int J Oncol , 29 :1381 , 2006
PubMedID: 17088975

Title : Comparative antibacterial activity of polymeric 3-alkylpyridinium salts isolated from the Mediterranean sponge Reniera sarai and their synthetic analogues - Chelossi_2006_Biomol.Eng_23_317
Author(s) : Chelossi E , Mancini I , Sepcic K , Turk T , Faimali M
Ref : Biomol Eng , 23 :317 , 2006
PubMedID: 17113346

Title : Synthesis and bioactivity of linear oligomers related to polymeric alkylpyridinium metabolites from the Mediterranean sponge Reniera sarai - Mancini_2004_Org.Biomol.Chem_2_1368
Author(s) : Mancini I , Sicurelli A , Guella G , Turk T , Macek P , Sepcic K
Ref : Org Biomol Chem , 2 :1368 , 2004
PubMedID: 15105928

Title : Non-toxic antifouling activity of polymeric 3-alkylpyridinium salts from the Mediterranean sponge Reniera sarai (Pulitzer-Finali) - Faimali_2003_Biofouling_19_47
Author(s) : Faimali M , Sepcic K , Turk T , Geraci S
Ref : Biofouling , 19 :47 , 2003
PubMedID: 14618688

Title : Irreversible and reversible pore formation by polymeric alkylpyridinium salts (poly-APS) from the sponge Reniera sarai - McClelland_2003_Br.J.Pharmacol_139_1399
Author(s) : McClelland D , Evans RM , Abidin I , Sharma S , Choudhry FZ , Jaspars M , Sepcic K , Scott RH
Ref : British Journal of Pharmacology , 139 :1399 , 2003
PubMedID: 12922926

Title : The influence of alkyl pyridinium sponge toxins on membrane properties, cytotoxicity, transfection and protein expression in mammalian cells - Tucker_2003_Biochim.Biophys.Acta_1614_171
Author(s) : Tucker SJ , McClelland D , Jaspars M , Sepcic K , MacEwan DJ , Scott RH
Ref : Biochimica & Biophysica Acta , 1614 :171 , 2003
PubMedID: 12896810

Title : Antibacterial and anticholinesterase activities of aplysamine-4, a bromotyrosine-derived metabolite of a Red Sea marine sponge - Sepcic_2001_J.Nat.Toxins_10_181
Author(s) : Sepcic K , Mancini I , Vidic I , Franssanito R , Pietra F , Macek P , Turk T
Ref : J Nat Toxins , 10 :181 , 2001
PubMedID: 11491458

Title : In vivo effects of head-to-tail 3-alkylpiridinium polymers isolated from the marine sponge Raniera sarai - Bunc_2000_Pflugers.Arch_440_R173
Author(s) : Bunc M , Sepcic K , Turk T , Suput D
Ref : Pflugers Arch , 440 :R173 , 2000
PubMedID: 11005659

Title : Interaction of 3-alkylpyridinium polymers from the sea sponge Reniera sarai with insect acetylcholinesterase - Sepcic_1999_J.Protein.Chem_18_251
Author(s) : Sepcic K , Poklar N , Vesnaver G , Fournier D , Turk T , Macek P
Ref : J Protein Chem , 18 :251 , 1999
PubMedID: 10395443

Title : Characterization of hemolytic activity of 3-alkylpyridinium polymers from the marine sponge Reniera sarai - Malovrh_1999_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_124_221
Author(s) : Malovrh P , Sepcic K , Turk T , Macek P
Ref : Comparative Biochemistry & Physiology C Pharmacol Toxicol Endocrinol , 124 :221 , 1999
PubMedID: 10622439

Title : Anticholinesterase activity of the fluorescent zoanthid pigment, parazoanthoxanthin A - Sepcic_1998_Toxicon_36_937
Author(s) : Sepcic K , Turk T , Macek P
Ref : Toxicon , 36 :937 , 1998
PubMedID: 9663700

Title : Inhibition of acetylcholinesterase by an alkylpyridinium polymer from the marine sponge, reniera sarai - Sepcic_1998_Biochim.Biophys.Acta_1387_217
Author(s) : Sepcic K , Marcel V , Klaebe A , Turk T , Suput D , Fournier D
Ref : Biochimica & Biophysica Acta , 1387 :217 , 1998
PubMedID: 9748587

Title : Biological activities of aqueous extracts from marine sponges and cytotoxic effects of 3-alkylpyridinium polymers from Reniera sarai - Sepcic_1997_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_117_47
Author(s) : Sepcic K , Batista U , Vacelet J , Macek P , Turk T
Ref : Comparative Biochemistry & Physiology C Pharmacology Toxicology & Endocrinology , 117 :47 , 1997
PubMedID: 9185326

Title : Characterization of anticholinesterase-active 3-alkylpyridinium polymers from the marine sponge Reniera sarai in aqueous solutions - Sepcic_1997_J.Nat.Prod_60_991
Author(s) : Sepcic K , Guella G , Mancini I , Pietra F , Serra MD , Menestrina G , Tubbs K , Macek P , Turk T
Ref : Journal of Natural Products , 60 :991 , 1997
PubMedID: 9358641