Full name : Groot-Kormelink Paul J
First name : Paul J
Mail : Janssen Research Foundation, Turnhoutseweg 30, B-2340 Beerse
Zip Code :
City :
Country : Belgium
Email : pgrootko@janbe-jnj.com
Phone : 32 14603965
Fax : 32 14606111
Website :
Directory :
Comment
Title : High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor - Groot-Kormelink_2016_PLoS.One_11_e0163129 |
Author(s) : Groot-Kormelink PJ , Ferrand S , Kelley N , Bill A , Freuler F , Imbert PE , Marelli A , Gerwin N , Sivilotti LG , Miraglia L , Orth AP , Oakeley EJ , Schopfer U , Siehler S |
Ref : PLoS ONE , 11 :e0163129 , 2016 |
Abstract : |
PubMedSearch : Groot-Kormelink_2016_PLoS.One_11_e0163129 |
PubMedID: 27649498 |
Title : Human alpha3beta4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells - Krashia_2010_PLoS.One_5_e13611 |
Author(s) : Krashia P , Moroni M , Broadbent S , Hofmann G , Kracun S , Beato M , Groot-Kormelink PJ , Sivilotti LG |
Ref : PLoS ONE , 5 :e13611 , 2010 |
Abstract : |
PubMedSearch : Krashia_2010_PLoS.One_5_e13611 |
PubMedID: 21049012 |
Title : Pentameric concatenated (alpha4)(2)(beta2)(3) and (alpha4)(3)(beta2)(2) nicotinic acetylcholine receptors: subunit arrangement determines functional expression - Carbone_2009_Br.J.Pharmacol_156_970 |
Author(s) : Carbone AL , Moroni M , Groot-Kormelink PJ , Bermudez I |
Ref : British Journal of Pharmacology , 156 :970 , 2009 |
Abstract : |
PubMedSearch : Carbone_2009_Br.J.Pharmacol_156_970 |
PubMedID: 19366353 |
Title : Single-channel study of the spasmodic mutation alpha1A52S in recombinant rat glycine receptors - Plested_2007_J.Physiol_581_51 |
Author(s) : Plested AJ , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG |
Ref : Journal of Physiology , 581 :51 , 2007 |
Abstract : |
PubMedSearch : Plested_2007_J.Physiol_581_51 |
PubMedID: 17331994 |
Title : Constraining the expression of nicotinic acetylcholine receptors by using pentameric constructs - Groot-Kormelink_2006_Mol.Pharmacol_69_558 |
Author(s) : Groot-Kormelink PJ , Broadbent S , Beato M , Sivilotti LG |
Ref : Molecular Pharmacology , 69 :558 , 2006 |
Abstract : |
PubMedSearch : Groot-Kormelink_2006_Mol.Pharmacol_69_558 |
PubMedID: 16269534 |
Title : Incorporation of the beta3 subunit has a dominant-negative effect on the function of recombinant central-type neuronal nicotinic receptors - Broadbent_2006_Mol.Pharmacol_70_1350 |
Author(s) : Broadbent S , Groot-Kormelink PJ , Krashia PA , Harkness PC , Millar NS , Beato M , Sivilotti LG |
Ref : Molecular Pharmacology , 70 :1350 , 2006 |
Abstract : |
PubMedSearch : Broadbent_2006_Mol.Pharmacol_70_1350 |
PubMedID: 16822928 |
Title : Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism - Smulders_2005_Eur.J.Pharmacol_509_97 |
Author(s) : Smulders CJ , Zwart R , Bermudez I , van Kleef RG , Groot-Kormelink PJ , Vijverberg HP |
Ref : European Journal of Pharmacology , 509 :97 , 2005 |
Abstract : |
PubMedSearch : Smulders_2005_Eur.J.Pharmacol_509_97 |
PubMedID: 15733544 |
Title : The activation mechanism of alpha1 homomeric glycine receptors - Beato_2004_J.Neurosci_24_895 |
Author(s) : Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG |
Ref : Journal of Neuroscience , 24 :895 , 2004 |
Abstract : |
PubMedSearch : Beato_2004_J.Neurosci_24_895 |
PubMedID: 14749434 |
Title : Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens - Burzomato_2004_J.Neurosci_24_10924 |
Author(s) : Burzomato V , Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG |
Ref : Journal of Neuroscience , 24 :10924 , 2004 |
Abstract : |
PubMedSearch : Burzomato_2004_J.Neurosci_24_10924 |
PubMedID: 15574743 |
Title : Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors - Groot-Kormelink_2004_J.Gen.Physiol_123_697 |
Author(s) : Groot-Kormelink PJ , Broadbent SD , Boorman JP , Sivilotti LG |
Ref : Journal of General Physiology , 123 :697 , 2004 |
Abstract : |
PubMedSearch : Groot-Kormelink_2004_J.Gen.Physiol_123_697 |
PubMedID: 15148328 |
Title : The effects of beta3 subunit incorporation on the pharmacology and single channel properties of oocyte-expressed human alpha3beta4 neuronal nicotinic receptors - Boorman_2003_J.Biol.Chem_278_44033 |
Author(s) : Boorman JP , Beato M , Groot-Kormelink PJ , Broadbent SD , Sivilotti LG |
Ref : Journal of Biological Chemistry , 278 :44033 , 2003 |
Abstract : |
PubMedSearch : Boorman_2003_J.Biol.Chem_278_44033 |
PubMedID: 12912995 |
Title : Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation - Burzomato_2003_Receptors.Channels_9_353 |
Author(s) : Burzomato V , Groot-Kormelink PJ , Sivilotti LG , Beato M |
Ref : Receptors Channels , 9 :353 , 2003 |
Abstract : |
PubMedSearch : Burzomato_2003_Receptors.Channels_9_353 |
PubMedID: 14698963 |
Title : Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound - Beato_2002_J.Gen.Physiol_119_443 |
Author(s) : Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG |
Ref : Journal of General Physiology , 119 :443 , 2002 |
Abstract : |
PubMedSearch : Beato_2002_J.Gen.Physiol_119_443 |
PubMedID: 11981023 |
Title : Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of alpha 1 glycine receptors in HEK293 cells - Groot-Kormelink_2002_J.Neurosci.Methods_113_207 |
Author(s) : Groot-Kormelink PJ , Beato M , Finotti C , Harvey RJ , Sivilotti LG |
Ref : Journal of Neuroscience Methods , 113 :207 , 2002 |
Abstract : |
PubMedSearch : Groot-Kormelink_2002_J.Neurosci.Methods_113_207 |
PubMedID: 11772442 |
Title : Formation of functional alpha3beta4alpha5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach - Groot-Kormelink_2001_Br.J.Pharmacol_134_789 |
Author(s) : Groot-Kormelink PJ , Boorman JP , Sivilotti LG |
Ref : British Journal of Pharmacology , 134 :789 , 2001 |
Abstract : |
PubMedSearch : Groot-Kormelink_2001_Br.J.Pharmacol_134_789 |
PubMedID: 11606319 |
Title : Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes - Boorman_2000_J.Physiol_529 Pt 3_565 |
Author(s) : Boorman JP , Groot-Kormelink PJ , Sivilotti LG |
Ref : Journal of Physiology , 529 Pt 3 :565 , 2000 |
Abstract : |
PubMedSearch : Boorman_2000_J.Physiol_529 Pt 3_565 |
PubMedID: 11118490 |
Title : A reporter mutation approach shows incorporation of the orphan subunit beta3 into a functional nicotinic receptor - Groot-Kormelink_1998_J.Biol.Chem_273_15317 |
Author(s) : Groot-Kormelink PJ , Luyten WH , Colquhoun D , Sivilotti LG |
Ref : Journal of Biological Chemistry , 273 :15317 , 1998 |
Abstract : |
PubMedSearch : Groot-Kormelink_1998_J.Biol.Chem_273_15317 |
PubMedID: 9624109 |