Groot-Kormelink PJ

General

Full name : Groot-Kormelink Paul J

First name : Paul J

Mail : Janssen Research Foundation, Turnhoutseweg 30, B-2340 Beerse

Zip Code :

City :

Country : Belgium

Email : pgrootko@janbe-jnj.com

Phone : 32 14603965

Fax : 32 14606111

Website :

Directory :

References (17)

Title : High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor - Groot-Kormelink_2016_PLoS.One_11_e0163129
Author(s) : Groot-Kormelink PJ , Ferrand S , Kelley N , Bill A , Freuler F , Imbert PE , Marelli A , Gerwin N , Sivilotti LG , Miraglia L , Orth AP , Oakeley EJ , Schopfer U , Siehler S
Ref : PLoS ONE , 11 :e0163129 , 2016
Abstract :
PubMedSearch : Groot-Kormelink_2016_PLoS.One_11_e0163129
PubMedID: 27649498

Title : Human alpha3beta4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells - Krashia_2010_PLoS.One_5_e13611
Author(s) : Krashia P , Moroni M , Broadbent S , Hofmann G , Kracun S , Beato M , Groot-Kormelink PJ , Sivilotti LG
Ref : PLoS ONE , 5 :e13611 , 2010
Abstract :
PubMedSearch : Krashia_2010_PLoS.One_5_e13611
PubMedID: 21049012

Title : Pentameric concatenated (alpha4)(2)(beta2)(3) and (alpha4)(3)(beta2)(2) nicotinic acetylcholine receptors: subunit arrangement determines functional expression - Carbone_2009_Br.J.Pharmacol_156_970
Author(s) : Carbone AL , Moroni M , Groot-Kormelink PJ , Bermudez I
Ref : British Journal of Pharmacology , 156 :970 , 2009
Abstract :
PubMedSearch : Carbone_2009_Br.J.Pharmacol_156_970
PubMedID: 19366353

Title : Single-channel study of the spasmodic mutation alpha1A52S in recombinant rat glycine receptors - Plested_2007_J.Physiol_581_51
Author(s) : Plested AJ , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG
Ref : Journal of Physiology , 581 :51 , 2007
Abstract :
PubMedSearch : Plested_2007_J.Physiol_581_51
PubMedID: 17331994

Title : Constraining the expression of nicotinic acetylcholine receptors by using pentameric constructs - Groot-Kormelink_2006_Mol.Pharmacol_69_558
Author(s) : Groot-Kormelink PJ , Broadbent S , Beato M , Sivilotti LG
Ref : Molecular Pharmacology , 69 :558 , 2006
Abstract :
PubMedSearch : Groot-Kormelink_2006_Mol.Pharmacol_69_558
PubMedID: 16269534

Title : Incorporation of the beta3 subunit has a dominant-negative effect on the function of recombinant central-type neuronal nicotinic receptors - Broadbent_2006_Mol.Pharmacol_70_1350
Author(s) : Broadbent S , Groot-Kormelink PJ , Krashia PA , Harkness PC , Millar NS , Beato M , Sivilotti LG
Ref : Molecular Pharmacology , 70 :1350 , 2006
Abstract :
PubMedSearch : Broadbent_2006_Mol.Pharmacol_70_1350
PubMedID: 16822928

Title : Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism - Smulders_2005_Eur.J.Pharmacol_509_97
Author(s) : Smulders CJ , Zwart R , Bermudez I , van Kleef RG , Groot-Kormelink PJ , Vijverberg HP
Ref : European Journal of Pharmacology , 509 :97 , 2005
Abstract :
PubMedSearch : Smulders_2005_Eur.J.Pharmacol_509_97
PubMedID: 15733544

Title : The activation mechanism of alpha1 homomeric glycine receptors - Beato_2004_J.Neurosci_24_895
Author(s) : Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG
Ref : Journal of Neuroscience , 24 :895 , 2004
Abstract :
PubMedSearch : Beato_2004_J.Neurosci_24_895
PubMedID: 14749434

Title : Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens - Burzomato_2004_J.Neurosci_24_10924
Author(s) : Burzomato V , Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG
Ref : Journal of Neuroscience , 24 :10924 , 2004
Abstract :
PubMedSearch : Burzomato_2004_J.Neurosci_24_10924
PubMedID: 15574743

Title : Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors - Groot-Kormelink_2004_J.Gen.Physiol_123_697
Author(s) : Groot-Kormelink PJ , Broadbent SD , Boorman JP , Sivilotti LG
Ref : Journal of General Physiology , 123 :697 , 2004
Abstract :
PubMedSearch : Groot-Kormelink_2004_J.Gen.Physiol_123_697
PubMedID: 15148328

Title : The effects of beta3 subunit incorporation on the pharmacology and single channel properties of oocyte-expressed human alpha3beta4 neuronal nicotinic receptors - Boorman_2003_J.Biol.Chem_278_44033
Author(s) : Boorman JP , Beato M , Groot-Kormelink PJ , Broadbent SD , Sivilotti LG
Ref : Journal of Biological Chemistry , 278 :44033 , 2003
Abstract :
PubMedSearch : Boorman_2003_J.Biol.Chem_278_44033
PubMedID: 12912995

Title : Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation - Burzomato_2003_Receptors.Channels_9_353
Author(s) : Burzomato V , Groot-Kormelink PJ , Sivilotti LG , Beato M
Ref : Receptors Channels , 9 :353 , 2003
Abstract :
PubMedSearch : Burzomato_2003_Receptors.Channels_9_353
PubMedID: 14698963

Title : Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound - Beato_2002_J.Gen.Physiol_119_443
Author(s) : Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG
Ref : Journal of General Physiology , 119 :443 , 2002
Abstract :
PubMedSearch : Beato_2002_J.Gen.Physiol_119_443
PubMedID: 11981023

Title : Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of alpha 1 glycine receptors in HEK293 cells - Groot-Kormelink_2002_J.Neurosci.Methods_113_207
Author(s) : Groot-Kormelink PJ , Beato M , Finotti C , Harvey RJ , Sivilotti LG
Ref : Journal of Neuroscience Methodsods , 113 :207 , 2002
Abstract :
PubMedSearch : Groot-Kormelink_2002_J.Neurosci.Methods_113_207
PubMedID: 11772442

Title : Formation of functional alpha3beta4alpha5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach - Groot-Kormelink_2001_Br.J.Pharmacol_134_789
Author(s) : Groot-Kormelink PJ , Boorman JP , Sivilotti LG
Ref : British Journal of Pharmacology , 134 :789 , 2001
Abstract :
PubMedSearch : Groot-Kormelink_2001_Br.J.Pharmacol_134_789
PubMedID: 11606319

Title : Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes - Boorman_2000_J.Physiol_529 Pt 3_565
Author(s) : Boorman JP , Groot-Kormelink PJ , Sivilotti LG
Ref : Journal of Physiology , 529 Pt 3 :565 , 2000
Abstract :
PubMedSearch : Boorman_2000_J.Physiol_529 Pt 3_565
PubMedID: 11118490

Title : A reporter mutation approach shows incorporation of the orphan subunit beta3 into a functional nicotinic receptor - Groot-Kormelink_1998_J.Biol.Chem_273_15317
Author(s) : Groot-Kormelink PJ , Luyten WH , Colquhoun D , Sivilotti LG
Ref : Journal of Biological Chemistry , 273 :15317 , 1998
Abstract :
PubMedSearch : Groot-Kormelink_1998_J.Biol.Chem_273_15317
PubMedID: 9624109