Bermudez I

General

Full name : Bermudez-Diaz Isabel

First name : Isabel

Mail : Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 OBD

Zip Code :

City :

Country : United Kingdom

Email : ibermudez@brookes.ac.uk

Phone :

Fax :

Website :

Directory :

References (35)

Title : Unraveling the molecular interactions between alpha7 nicotinic receptor and a RIC3 variant associated with backward speech - Pradhan_2024_Cell.Mol.Life.Sci_81_129
Author(s) : Pradhan A , Mounford H , Peixinho J , Rea E , Epeslidou E , Scott JS , Cull J , Maxwell S , Webster R , Beeson D , Dong YY , Prekovic S , Bermudez I , Newbury DF
Ref : Cell Mol Life Sciences , 81 :129 , 2024
Abstract :
PubMedSearch : Pradhan_2024_Cell.Mol.Life.Sci_81_129
PubMedID: 38472514

Title : Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR - Epstein_2021_Toxicol.Lett__
Author(s) : Epstein M , Bali K , Piggot TJ , Green AC , Timperley CM , Bird M , Tattersall JEH , Bermudez I , Biggin PC
Ref : Toxicol Lett , : , 2021
Abstract :
PubMedSearch : Epstein_2021_Toxicol.Lett__
PubMedID: 33482275

Title : Non-equivalent Ligand Selectivity of Agonist Sites in (alpha4beta2)2alpha4 Nicotinic Acetylcholine Receptors: A KEY DETERMINANT OF AGONIST EFFICACY - Mazzaferro_2014_J.Biol.Chem_289_21795
Author(s) : Mazzaferro S , Gasparri F , New K , Alcaino C , Faundez M , Iturriaga Vasquez P , Vijayan R , Biggin PC , Bermudez I
Ref : Journal of Biological Chemistry , 289 :21795 , 2014
Abstract :
PubMedSearch : Mazzaferro_2014_J.Biol.Chem_289_21795
PubMedID: 24936069

Title : The nicotinic alpha5 subunit can replace either an acetylcholine-binding or nonbinding subunit in the alpha4beta2* neuronal nicotinic receptor - Jin_2014_Mol.Pharmacol_85_11
Author(s) : Jin X , Bermudez I , Steinbach JH
Ref : Molecular Pharmacology , 85 :11 , 2014
Abstract :
PubMedSearch : Jin_2014_Mol.Pharmacol_85_11
PubMedID: 24184962

Title : Striatal dopamine transmission is reduced after chronic nicotine with a decrease in alpha6-nicotinic receptor control in nucleus accumbens - Exley_2013_Eur.J.Neurosci_38_3036
Author(s) : Exley R , Clements MA , Hartung H , McIntosh JM , Franklin M , Bermudez I , Cragg SJ
Ref : European Journal of Neuroscience , 38 :3036 , 2013
Abstract :
PubMedSearch : Exley_2013_Eur.J.Neurosci_38_3036
PubMedID: 23841846

Title : Neonicotinic analogues: selective antagonists for alpha4beta2 nicotinic acetylcholine receptors - Faundez-Parraguez_2013_Bioorg.Med.Chem_21_2687
Author(s) : Faundez-Parraguez M , Farias-Rabelo N , Gonzalez-Gutierrez JP , Etcheverry-Berrios A , Alzate-Morales J , Adasme-Carreno F , Varas R , Bermudez I , Iturriaga-Vasquez P
Ref : Bioorganic & Medicinal Chemistry , 21 :2687 , 2013
Abstract :
PubMedSearch : Faundez-Parraguez_2013_Bioorg.Med.Chem_21_2687
PubMedID: 23561269

Title : The additional ACh binding site at the alpha4(+)\/alpha4(-) interface of the (alpha4beta2)2alpha4 nicotinic ACh receptor contributes to desensitization - Benallegue_2013_Br.J.Pharmacol_170_304
Author(s) : Benallegue N , Mazzaferro S , Alcaino C , Bermudez I
Ref : British Journal of Pharmacology , 170 :304 , 2013
Abstract :
PubMedSearch : Benallegue_2013_Br.J.Pharmacol_170_304
PubMedID: 23742319

Title : Allosteric modulators of alpha4beta2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery - Mantione_2012_Future.Med.Chem_4_2217
Author(s) : Mantione E , Micheloni S , Alcaino C , New K , Mazzaferro S , Bermudez I
Ref : Future Med Chem , 4 :2217 , 2012
Abstract :
PubMedSearch : Mantione_2012_Future.Med.Chem_4_2217
PubMedID: 23190109

Title : Additional acetylcholine (ACh) binding site at alpha4\/alpha4 interface of (alpha4beta2)2alpha4 nicotinic receptor influences agonist sensitivity - Mazzaferro_2011_J.Biol.Chem_286_31043
Author(s) : Mazzaferro S , Benallegue N , Carbone A , Gasparri F , Vijayan R , Biggin PC , Moroni M , Bermudez I
Ref : Journal of Biological Chemistry , 286 :31043 , 2011
Abstract :
PubMedSearch : Mazzaferro_2011_J.Biol.Chem_286_31043
PubMedID: 21757735

Title : Poster: Tethered pentamersLow sensitivity alpha4\/beta2-nicotinic acetylcholine receptors -
Author(s) : Lucero L , Bhakta M , Liu G , Wu J , Hauser TA , Bencherif M , Bermudez I , Whiteaker P , Lukas RJ
Ref : Biochemical Pharmacology , 82 :1025 , 2011
PubMedID:

Title : Molecular determinants for competitive inhibition of alpha4beta2 nicotinic acetylcholine receptors - Iturriaga-Vasquez_2010_Mol.Pharmacol_78_366
Author(s) : Iturriaga-Vasquez P , Carbone A , Garcia-Beltran O , Livingstone PD , Biggin PC , Cassels BK , Wonnacott S , Zapata-Torres G , Bermudez I
Ref : Molecular Pharmacology , 78 :366 , 2010
Abstract :
PubMedSearch : Iturriaga-Vasquez_2010_Mol.Pharmacol_78_366
PubMedID: 20547737

Title : Pentameric concatenated (alpha4)(2)(beta2)(3) and (alpha4)(3)(beta2)(2) nicotinic acetylcholine receptors: subunit arrangement determines functional expression - Carbone_2009_Br.J.Pharmacol_156_970
Author(s) : Carbone AL , Moroni M , Groot-Kormelink PJ , Bermudez I
Ref : British Journal of Pharmacology , 156 :970 , 2009
Abstract :
PubMedSearch : Carbone_2009_Br.J.Pharmacol_156_970
PubMedID: 19366353

Title : Non-agonist-binding subunit interfaces confer distinct functional signatures to the alternate stoichiometries of the alpha4beta2 nicotinic receptor: an alpha4-alpha4 interface is required for Zn2+ potentiation - Moroni_2008_J.Neurosci_28_6884
Author(s) : Moroni M , Vijayan R , Carbone A , Zwart R , Biggin PC , Bermudez I
Ref : Journal of Neuroscience , 28 :6884 , 2008
Abstract :
PubMedSearch : Moroni_2008_J.Neurosci_28_6884
PubMedID: 18596163

Title : Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors - Zwart_2008_Mol.Pharmacol_73_1838
Author(s) : Zwart R , Carbone AL , Moroni M , Bermudez I , Mogg AJ , Folly EA , Broad LM , Williams AC , Zhang D , Ding C , Heinz BA , Sher E
Ref : Molecular Pharmacology , 73 :1838 , 2008
Abstract :
PubMedSearch : Zwart_2008_Mol.Pharmacol_73_1838
PubMedID: 18367540

Title : Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers - Iturriaga-Vasquez_2007_Bioorg.Med.Chem_15_3368
Author(s) : Iturriaga-Vasquez P , Perez EG , Slater EY , Bermudez I , Cassels BK
Ref : Bioorganic & Medicinal Chemistry , 15 :3368 , 2007
Abstract :
PubMedSearch : Iturriaga-Vasquez_2007_Bioorg.Med.Chem_15_3368
PubMedID: 17391965

Title : Stoichiometry and pharmacology of two human alpha4beta2 nicotinic receptor types - Moroni_2006_J.Mol.Neurosci_30_95
Author(s) : Moroni M , Bermudez I
Ref : Journal of Molecular Neuroscience , 30 :95 , 2006
Abstract :
PubMedSearch : Moroni_2006_J.Mol.Neurosci_30_95
PubMedID: 17192644

Title : alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine - Moroni_2006_Mol.Pharmacol_70_755
Author(s) : Moroni M , Zwart R , Sher E , Cassels BK , Bermudez I
Ref : Molecular Pharmacology , 70 :755 , 2006
Abstract :
PubMedSearch : Moroni_2006_Mol.Pharmacol_70_755
PubMedID: 16720757

Title : C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists - Abin-Carriquiry_2006_Eur.J.Pharmacol_536_1
Author(s) : Abin-Carriquiry JA , Voutilainen MH , Barik J , Cassels BK , Iturriaga-Vasquez P , Bermudez I , Durand C , Dajas F , Wonnacott S
Ref : European Journal of Pharmacology , 536 :1 , 2006
Abstract :
PubMedSearch : Abin-Carriquiry_2006_Eur.J.Pharmacol_536_1
PubMedID: 16563372

Title : 5-I A-85380 and TC-2559 differentially activate heterologously expressed alpha4beta2 nicotinic receptors - Zwart_2006_Eur.J.Pharmacol_539_10
Author(s) : Zwart R , Broad LM , Xi Q , Lee M , Moroni M , Bermudez I , Sher E
Ref : European Journal of Pharmacology , 539 :10 , 2006
Abstract :
PubMedSearch : Zwart_2006_Eur.J.Pharmacol_539_10
PubMedID: 16674940

Title : Phosphorylation and function of alpha4beta2 receptor - Bermudez_2006_J.Mol.Neurosci_30_97
Author(s) : Bermudez I , Moroni M
Ref : Journal of Molecular Neuroscience , 30 :97 , 2006
Abstract :
PubMedSearch : Bermudez_2006_J.Mol.Neurosci_30_97
PubMedID: 17192645

Title : Chaperone protein 14-3-3 and protein kinase A increase the relative abundance of low agonist sensitivity human alpha 4 beta 2 nicotinic acetylcholine receptors in Xenopus oocytes - Exley_2006_J.Neurochem_98_876
Author(s) : Exley R , Moroni M , Sasdelli F , Houlihan LM , Lukas RJ , Sher E , Zwart R , Bermudez I
Ref : Journal of Neurochemistry , 98 :876 , 2006
Abstract :
PubMedSearch : Exley_2006_J.Neurochem_98_876
PubMedID: 16787419

Title : Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism - Smulders_2005_Eur.J.Pharmacol_509_97
Author(s) : Smulders CJ , Zwart R , Bermudez I , van Kleef RG , Groot-Kormelink PJ , Vijverberg HP
Ref : European Journal of Pharmacology , 509 :97 , 2005
Abstract :
PubMedSearch : Smulders_2005_Eur.J.Pharmacol_509_97
PubMedID: 15733544

Title : Alpha7-acetylcholine receptor antibodies in two patients with Rasmussen encephalitis - Watson_2005_Neurology_65_1802
Author(s) : Watson R , Jepson JE , Bermudez I , Alexander S , Hart Y , McKnight K , Roubertie A , Fecto F , Valmier J , Sattelle DB , Beeson D , Vincent A , Lang B
Ref : Neurology , 65 :1802 , 2005
Abstract :
PubMedSearch : Watson_2005_Neurology_65_1802
PubMedID: 16344526

Title : Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors - Exley_2005_Br.J.Pharmacol_146_15
Author(s) : Exley R , Iturriaga-Vasquez P , Lukas RJ , Sher E , Cassels BK , Bermudez I
Ref : British Journal of Pharmacology , 146 :15 , 2005
Abstract :
PubMedSearch : Exley_2005_Br.J.Pharmacol_146_15
PubMedID: 15980871

Title : From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research - Cassels_2005_Drug.Discov.Today_10_1657
Author(s) : Cassels BK , Bermudez I , Dajas F , Abin-Carriquiry JA , Wonnacott S
Ref : Drug Discov Today , 10 :1657 , 2005
Abstract :
PubMedSearch : Cassels_2005_Drug.Discov.Today_10_1657
PubMedID: 16376826

Title : Absence of antibodies to glutamate receptor type 3 (GluR3) in Rasmussen encephalitis - Watson_2004_Neurology_63_43
Author(s) : Watson R , Jiang Y , Bermudez I , Houlihan LM , Clover L , McKnight K , Cross JH , Hart IK , Roubertie A , Valmier J , Hart Y , Palace J , Beeson D , Vincent A , Lang B
Ref : Neurology , 63 :43 , 2004
Abstract :
PubMedSearch : Watson_2004_Neurology_63_43
PubMedID: 15249609

Title : A novel peptide modulates alpha7 nicotinic receptor responses: implications for a possible trophic-toxic mechanism within the brain - Greenfield_2004_J.Neurochem_90_325
Author(s) : Greenfield SA , Day T , Mann EO , Bermudez I
Ref : Journal of Neurochemistry , 90 :325 , 2004
Abstract :
PubMedSearch : Greenfield_2004_J.Neurochem_90_325
PubMedID: 15228589

Title : The agonist biphasic dose-response curve of human alpha4beta2 nicotinic acetylcholine receptors is influenced by Ca2+ ions and pho. -
Author(s) : Bermudez I , Houlihan LM
Ref : Cholinergic Mechanisms, CRC Press :471 , 2004
PubMedID:

Title : Inhibition of human alpha 7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors - Maskell_2003_Br.J.Pharmacol_140_1313
Author(s) : Maskell PD , Speder P , Newberry NR , Bermudez I
Ref : British Journal of Pharmacology , 140 :1313 , 2003
Abstract :
PubMedSearch : Maskell_2003_Br.J.Pharmacol_140_1313
PubMedID: 14645141

Title : Halogenated cytisine derivatives as agonists at human neuronal nicotinic acetylcholine receptor subtypes - Slater_2003_Neuropharmacol_44_503
Author(s) : Slater YE , Houlihan LM , Maskell PD , Exley R , Bermudez I , Lukas RJ , Valdivia AC , Cassels BK
Ref : Neuropharmacology , 44 :503 , 2003
Abstract :
PubMedSearch : Slater_2003_Neuropharmacol_44_503
PubMedID: 12646287

Title : Pharmacological properties of nicotinic acetylcholine receptors in isolated Locusta migratoria neurones - Jackson_2002_Microsc.Res.Tech_56_249
Author(s) : Jackson C , Bermudez I , Beadle DJ
Ref : Microsc Res Tech , 56 :249 , 2002
Abstract :
PubMedSearch : Jackson_2002_Microsc.Res.Tech_56_249
PubMedID: 11877800

Title : Effects of the plant alkaloid tetrandrine on human nicotinic acetylcholine receptors - Slater_2002_Eur.J.Pharmacol_450_213
Author(s) : Slater Y , Houlihan LM , Cassels BK , Lukas RJ , Bermudez I
Ref : European Journal of Pharmacology , 450 :213 , 2002
Abstract :
PubMedSearch : Slater_2002_Eur.J.Pharmacol_450_213
PubMedID: 12208312

Title : Activity of cytisine and its brominated isosteres on recombinant human alpha7, alpha4beta2 and alpha4beta4 nicotinic acetylcholine receptors - Houlihan_2001_J.Neurochem_78_1029
Author(s) : Houlihan LM , Slater Y , Guerra DL , Peng JH , Kuo YP , Lukas RJ , Cassels BK , Bermudez I
Ref : Journal of Neurochemistry , 78 :1029 , 2001
Abstract :
PubMedSearch : Houlihan_2001_J.Neurochem_78_1029
PubMedID: 11553677

Title : Effects of diltiazem on human nicotinic acetylcholine and GABA(A) receptors - Houlihan_2000_Neuropharmacol_39_2533
Author(s) : Houlihan LM , Slater EY , Beadle DJ , Lukas RJ , Bermudez I
Ref : Neuropharmacology , 39 :2533 , 2000
Abstract :
PubMedSearch : Houlihan_2000_Neuropharmacol_39_2533
PubMedID: 11044725

Title : Stable functional expression of the adult subtype of human muscle acetylcholine receptor following transfection of the human rhabdomyosarcoma cell line TE671 with cDNA encoding the epsilon subunit - Beeson_1996_Neurosci.Lett_207_57
Author(s) : Beeson D , Amar M , Bermudez I , Vincent A , Newsom-Davis J
Ref : Neuroscience Letters , 207 :57 , 1996
Abstract :
PubMedSearch : Beeson_1996_Neurosci.Lett_207_57
PubMedID: 8710210