| Title : From bench to brain: novel thieno-oxazine hybrids as potent pleiotropic anti-Alzheimer's agents with in vivo\/in vitro validation and in silico insights - Fayed_2026_J.Enzyme.Inhib.Med.Chem_41_2598741 |
| Author(s) : Fayed EA , M AAN , Oudah KH , Ebrahim MA , Gohar NA , Abu-Elfotuh K , Khedre Mohamed E , Hamdan AME , Albalawi NA , Faisal Alzahrani S , Hamdan AM , Almotairi R , Hafez SM , Ramsis TM |
| Ref : J Enzyme Inhib Med Chem , 41 :2598741 , 2026 |
| Abstract : |
| PubMedSearch : Fayed_2026_J.Enzyme.Inhib.Med.Chem_41_2598741 |
| PubMedID: 41481412 |
| Title : From bench to brain: novel thieno-oxazine hybrids as potent pleiotropic anti-Alzheimer's agents with in vivo\/in vitro validation and in silico insights - Fayed_2026_J.Enzyme.Inhib.Med.Chem_41_2598741 |
| Author(s) : Fayed EA , M AAN , Oudah KH , Ebrahim MA , Gohar NA , Abu-Elfotuh K , Khedre Mohamed E , Hamdan AME , Albalawi NA , Faisal Alzahrani S , Hamdan AM , Almotairi R , Hafez SM , Ramsis TM |
| Ref : J Enzyme Inhib Med Chem , 41 :2598741 , 2026 |
| Abstract : |
| PubMedSearch : Fayed_2026_J.Enzyme.Inhib.Med.Chem_41_2598741 |
| PubMedID: 41481412 |
| Title : From bench to brain: novel thieno-oxazine hybrids as potent pleiotropic anti-Alzheimer's agents with in vivo\/in vitro validation and in silico insights - Fayed_2026_J.Enzyme.Inhib.Med.Chem_41_2598741 |
| Author(s) : Fayed EA , M AAN , Oudah KH , Ebrahim MA , Gohar NA , Abu-Elfotuh K , Khedre Mohamed E , Hamdan AME , Albalawi NA , Faisal Alzahrani S , Hamdan AM , Almotairi R , Hafez SM , Ramsis TM |
| Ref : J Enzyme Inhib Med Chem , 41 :2598741 , 2026 |
| Abstract : |
| PubMedSearch : Fayed_2026_J.Enzyme.Inhib.Med.Chem_41_2598741 |
| PubMedID: 41481412 |
| Title : Unlocking Therapeutic Potential of Novel Thieno-Oxazepine Hybrids as Multi-Target Inhibitors of AChE\/BChE and Evaluation Against Alzheimer's Disease: In Vivo, In Vitro, Histopathological, and Docking Studies - Oudah_2025_Pharmaceuticals.(Basel)_18_ |
| Author(s) : Oudah KH , Najm MAA , Ramsis TM , Ebrahim MA , Gohar NA , Abu-Elfotuh K , Mohamed EK , Hamdan AME , Hamdan AM , Almotairi R , Abdelmohsen SR , Abdelhakim KR , Elsharkawy AMA , Fayed EA |
| Ref : Pharmaceuticals (Basel) , 18 : , 2025 |
| Abstract : |
| PubMedSearch : Oudah_2025_Pharmaceuticals.(Basel)_18_ |
| PubMedID: 40872605 |
| Title : Unlocking Therapeutic Potential of Novel Thieno-Oxazepine Hybrids as Multi-Target Inhibitors of AChE\/BChE and Evaluation Against Alzheimer's Disease: In Vivo, In Vitro, Histopathological, and Docking Studies - Oudah_2025_Pharmaceuticals.(Basel)_18_ |
| Author(s) : Oudah KH , Najm MAA , Ramsis TM , Ebrahim MA , Gohar NA , Abu-Elfotuh K , Mohamed EK , Hamdan AME , Hamdan AM , Almotairi R , Abdelmohsen SR , Abdelhakim KR , Elsharkawy AMA , Fayed EA |
| Ref : Pharmaceuticals (Basel) , 18 : , 2025 |
| Abstract : |
| PubMedSearch : Oudah_2025_Pharmaceuticals.(Basel)_18_ |
| PubMedID: 40872605 |
| Title : Unlocking Therapeutic Potential of Novel Thieno-Oxazepine Hybrids as Multi-Target Inhibitors of AChE\/BChE and Evaluation Against Alzheimer's Disease: In Vivo, In Vitro, Histopathological, and Docking Studies - Oudah_2025_Pharmaceuticals.(Basel)_18_ |
| Author(s) : Oudah KH , Najm MAA , Ramsis TM , Ebrahim MA , Gohar NA , Abu-Elfotuh K , Mohamed EK , Hamdan AME , Hamdan AM , Almotairi R , Abdelmohsen SR , Abdelhakim KR , Elsharkawy AMA , Fayed EA |
| Ref : Pharmaceuticals (Basel) , 18 : , 2025 |
| Abstract : |
| PubMedSearch : Oudah_2025_Pharmaceuticals.(Basel)_18_ |
| PubMedID: 40872605 |
| Title : Discovery of novel bicyclic and tricyclic cyclohepta[b]thiophene derivatives as multipotent AChE and BChE inhibitors, in-Vivo and in-Vitro assays, ADMET and molecular docking simulation - Fayed_2024_Eur.J.Med.Chem_284_117201 |
| Author(s) : Fayed EA , El-Sebaey SA , Ebrahim MA , Abu-Elfotuh K , El-Sayed Mansour R , Mohamed EK , Hamdan AME , Al-Subaie FT , Albalawi GS , Albalawi TM , Hamdan AM , Mohammed AA , Ramsis TM |
| Ref : Eur Journal of Medicinal Chemistry , 284 :117201 , 2024 |
| Abstract : |
| PubMedSearch : Fayed_2024_Eur.J.Med.Chem_284_117201 |
| PubMedID: 39731791 |
| Title : Neuroprotective effects of punicalagin and\/or micronized zeolite clinoptilolite on manganese-induced Parkinson's disease in a rat model: Involvement of multiple pathways - Abu-Elfotuh_2024_CNS.Neurosci.Ther_30_e70008 |
| Author(s) : Abu-Elfotuh K , Abbas AN , Najm MAA , Qasim QA , Hamdan AME , Abdelrehim AB , Gowifel AMH , Al-Najjar AH , Atwa AM , Kozman MR , Khalil AS , Negm AM , Mousa SNM , Hamdan AM , Abd El-Rhman RH , Abdelmohsen SR , Tolba AMA , Aboelsoud HA , Salahuddin A , Darwish A |
| Ref : CNS Neurosci Ther , 30 :e70008 , 2024 |
| Abstract : |
| PubMedSearch : Abu-Elfotuh_2024_CNS.Neurosci.Ther_30_e70008 |
| PubMedID: 39374157 |
| Title : Neuroprotective effects of punicalagin and\/or micronized zeolite clinoptilolite on manganese-induced Parkinson's disease in a rat model: Involvement of multiple pathways - Abu-Elfotuh_2024_CNS.Neurosci.Ther_30_e70008 |
| Author(s) : Abu-Elfotuh K , Abbas AN , Najm MAA , Qasim QA , Hamdan AME , Abdelrehim AB , Gowifel AMH , Al-Najjar AH , Atwa AM , Kozman MR , Khalil AS , Negm AM , Mousa SNM , Hamdan AM , Abd El-Rhman RH , Abdelmohsen SR , Tolba AMA , Aboelsoud HA , Salahuddin A , Darwish A |
| Ref : CNS Neurosci Ther , 30 :e70008 , 2024 |
| Abstract : |
| PubMedSearch : Abu-Elfotuh_2024_CNS.Neurosci.Ther_30_e70008 |
| PubMedID: 39374157 |
| Title : Neuroprotective effects of punicalagin and\/or micronized zeolite clinoptilolite on manganese-induced Parkinson's disease in a rat model: Involvement of multiple pathways - Abu-Elfotuh_2024_CNS.Neurosci.Ther_30_e70008 |
| Author(s) : Abu-Elfotuh K , Abbas AN , Najm MAA , Qasim QA , Hamdan AME , Abdelrehim AB , Gowifel AMH , Al-Najjar AH , Atwa AM , Kozman MR , Khalil AS , Negm AM , Mousa SNM , Hamdan AM , Abd El-Rhman RH , Abdelmohsen SR , Tolba AMA , Aboelsoud HA , Salahuddin A , Darwish A |
| Ref : CNS Neurosci Ther , 30 :e70008 , 2024 |
| Abstract : |
| PubMedSearch : Abu-Elfotuh_2024_CNS.Neurosci.Ther_30_e70008 |
| PubMedID: 39374157 |
| Title : Discovery of novel bicyclic and tricyclic cyclohepta[b]thiophene derivatives as multipotent AChE and BChE inhibitors, in-Vivo and in-Vitro assays, ADMET and molecular docking simulation - Fayed_2024_Eur.J.Med.Chem_284_117201 |
| Author(s) : Fayed EA , El-Sebaey SA , Ebrahim MA , Abu-Elfotuh K , El-Sayed Mansour R , Mohamed EK , Hamdan AME , Al-Subaie FT , Albalawi GS , Albalawi TM , Hamdan AM , Mohammed AA , Ramsis TM |
| Ref : Eur Journal of Medicinal Chemistry , 284 :117201 , 2024 |
| Abstract : |
| PubMedSearch : Fayed_2024_Eur.J.Med.Chem_284_117201 |
| PubMedID: 39731791 |
| Title : Discovery of novel bicyclic and tricyclic cyclohepta[b]thiophene derivatives as multipotent AChE and BChE inhibitors, in-Vivo and in-Vitro assays, ADMET and molecular docking simulation - Fayed_2024_Eur.J.Med.Chem_284_117201 |
| Author(s) : Fayed EA , El-Sebaey SA , Ebrahim MA , Abu-Elfotuh K , El-Sayed Mansour R , Mohamed EK , Hamdan AME , Al-Subaie FT , Albalawi GS , Albalawi TM , Hamdan AM , Mohammed AA , Ramsis TM |
| Ref : Eur Journal of Medicinal Chemistry , 284 :117201 , 2024 |
| Abstract : |
| PubMedSearch : Fayed_2024_Eur.J.Med.Chem_284_117201 |
| PubMedID: 39731791 |
| Title : Evaluating the neuroprotective activities of vinpocetine, punicalagin, niacin and vitamin E against behavioural and motor disabilities of manganese-induced Parkinson's disease in Sprague Dawley rats - Abu-Elfotuh_2022_Biomed.Pharmacother_153_113330 |
| Author(s) : Abu-Elfotuh K , Hamdan AME , Abbas AN , Alahmre ATS , Elewa MAF , Masoud RAE , Ali AA , Othman M , Kamal MM , Hassan FAM , Khalil MG , El-Sisi AM , Abdel Hady MMM , Abd-Elhaleim El Azazy MK , Awny MM , Wahid A |
| Ref : Biomed Pharmacother , 153 :113330 , 2022 |
| Abstract : |
| PubMedSearch : Abu-Elfotuh_2022_Biomed.Pharmacother_153_113330 |
| PubMedID: 35780621 |
| Title : Evaluating the neuroprotective activities of vinpocetine, punicalagin, niacin and vitamin E against behavioural and motor disabilities of manganese-induced Parkinson's disease in Sprague Dawley rats - Abu-Elfotuh_2022_Biomed.Pharmacother_153_113330 |
| Author(s) : Abu-Elfotuh K , Hamdan AME , Abbas AN , Alahmre ATS , Elewa MAF , Masoud RAE , Ali AA , Othman M , Kamal MM , Hassan FAM , Khalil MG , El-Sisi AM , Abdel Hady MMM , Abd-Elhaleim El Azazy MK , Awny MM , Wahid A |
| Ref : Biomed Pharmacother , 153 :113330 , 2022 |
| Abstract : |
| PubMedSearch : Abu-Elfotuh_2022_Biomed.Pharmacother_153_113330 |
| PubMedID: 35780621 |
| Title : Evaluating the neuroprotective activities of vinpocetine, punicalagin, niacin and vitamin E against behavioural and motor disabilities of manganese-induced Parkinson's disease in Sprague Dawley rats - Abu-Elfotuh_2022_Biomed.Pharmacother_153_113330 |
| Author(s) : Abu-Elfotuh K , Hamdan AME , Abbas AN , Alahmre ATS , Elewa MAF , Masoud RAE , Ali AA , Othman M , Kamal MM , Hassan FAM , Khalil MG , El-Sisi AM , Abdel Hady MMM , Abd-Elhaleim El Azazy MK , Awny MM , Wahid A |
| Ref : Biomed Pharmacother , 153 :113330 , 2022 |
| Abstract : |
| PubMedSearch : Abu-Elfotuh_2022_Biomed.Pharmacother_153_113330 |
| PubMedID: 35780621 |