| Title : Design, Synthesis, and Evaluation of 1-Benzylpiperidine and 1-Benzoylpiperidine Derivatives as Dual-Target Inhibitors of Acetylcholinesterase and Serotonin Transporter for Alzheimer's Disease - Gonzalez-Gutierrez_2025_Molecules_30_ |
| Author(s) : Gonzalez-Gutierrez JP , Castillo-Rios D , Rios-Campos V , Gonzalez-Gutierrez IA , Flores Melivilu D , Hormazabal Uribe E , Moraga-Nicolas F , Segura K , Hernandez V , Farias-Cea A , Pessoa-Mahana HA , Reyes-Parada MI , Iturriaga-Vasquez P |
| Ref : Molecules , 30 : , 2025 |
| Abstract : |
| PubMedSearch : Gonzalez-Gutierrez_2025_Molecules_30_ |
| PubMedID: 40733311 |
| Title : Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease - Rodriguez-Lavado_2020_Eur.J.Med.Chem_198_112368 |
| Author(s) : Rodriguez-Lavado J , Gallardo-Garrido C , Mallea M , Bustos V , Osorio R , Hodar-Salazar M , Chung H , Araya-Maturana R , Lorca M , Pessoa-Mahana CD , Mella-Raipan J , Saitz C , Jaque P , Reyes-Parada M , Iturriaga-Vasquez P , Pessoa-Mahana H |
| Ref : Eur Journal of Medicinal Chemistry , 198 :112368 , 2020 |
| Abstract : |
| PubMedSearch : Rodriguez-Lavado_2020_Eur.J.Med.Chem_198_112368 |
| PubMedID: 32388114 |
| Title : Synthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core - Mendez-Rojas_2018_Arch.Pharm.(Weinheim)_351_e1800024 |
| Author(s) : Mendez-Rojas C , Quiroz G , Faundez M , Gallardo-Garrido C , Pessoa-Mahana CD , Chung H , Gallardo-Toledo E , Saitz-Barria C , Araya-Maturana R , Kogan MJ , Zuniga-Lopez MC , Iturriaga-Vasquez P , Valenzuela-Gutierrez C , Pessoa-Mahana H |
| Ref : Arch Pharm (Weinheim) , 351 :e1800024 , 2018 |
| Abstract : |
| PubMedSearch : Mendez-Rojas_2018_Arch.Pharm.(Weinheim)_351_e1800024 |
| PubMedID: 29611620 |
| Title : Neonicotinic analogues: selective antagonists for alpha4beta2 nicotinic acetylcholine receptors - Faundez-Parraguez_2013_Bioorg.Med.Chem_21_2687 |
| Author(s) : Faundez-Parraguez M , Farias-Rabelo N , Gonzalez-Gutierrez JP , Etcheverry-Berrios A , Alzate-Morales J , Adasme-Carreno F , Varas R , Bermudez I , Iturriaga-Vasquez P |
| Ref : Bioorganic & Medicinal Chemistry , 21 :2687 , 2013 |
| Abstract : |
| PubMedSearch : Faundez-Parraguez_2013_Bioorg.Med.Chem_21_2687 |
| PubMedID: 23561269 |
| Title : Molecular determinants for competitive inhibition of alpha4beta2 nicotinic acetylcholine receptors - Iturriaga-Vasquez_2010_Mol.Pharmacol_78_366 |
| Author(s) : Iturriaga-Vasquez P , Carbone A , Garcia-Beltran O , Livingstone PD , Biggin PC , Cassels BK , Wonnacott S , Zapata-Torres G , Bermudez I |
| Ref : Molecular Pharmacology , 78 :366 , 2010 |
| Abstract : |
| PubMedSearch : Iturriaga-Vasquez_2010_Mol.Pharmacol_78_366 |
| PubMedID: 20547737 |
| Title : Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers - Iturriaga-Vasquez_2007_Bioorg.Med.Chem_15_3368 |
| Author(s) : Iturriaga-Vasquez P , Perez EG , Slater EY , Bermudez I , Cassels BK |
| Ref : Bioorganic & Medicinal Chemistry , 15 :3368 , 2007 |
| Abstract : |
| PubMedSearch : Iturriaga-Vasquez_2007_Bioorg.Med.Chem_15_3368 |
| PubMedID: 17391965 |
| Title : C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists - Abin-Carriquiry_2006_Eur.J.Pharmacol_536_1 |
| Author(s) : Abin-Carriquiry JA , Voutilainen MH , Barik J , Cassels BK , Iturriaga-Vasquez P , Bermudez I , Durand C , Dajas F , Wonnacott S |
| Ref : European Journal of Pharmacology , 536 :1 , 2006 |
| Abstract : |
| PubMedSearch : Abin-Carriquiry_2006_Eur.J.Pharmacol_536_1 |
| PubMedID: 16563372 |
| Title : Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors - Exley_2005_Br.J.Pharmacol_146_15 |
| Author(s) : Exley R , Iturriaga-Vasquez P , Lukas RJ , Sher E , Cassels BK , Bermudez I |
| Ref : British Journal of Pharmacology , 146 :15 , 2005 |
| Abstract : |
| PubMedSearch : Exley_2005_Br.J.Pharmacol_146_15 |
| PubMedID: 15980871 |