| Title : Efficacy and Safety of CAP7.1 as Second-Line Treatment for Advanced Biliary Tract Cancers: Data from a Randomised Phase II Study - Pape_2020_Cancers.(Basel)_12_ |
| Author(s) : Pape UF , Kasper S , Meiler J , Sinn M , Vogel A , Muller L , Burkhard O , Caca K , Heeg S , Buchner-Steudel P , Rodriguez-Laval V , Kuhl AA , Arsenic R , Jansen H , Treasure P , Utku N |
| Ref : Cancers (Basel) , 12 : , 2020 |
| Abstract : |
| PubMedSearch : Pape_2020_Cancers.(Basel)_12_ |
| PubMedID: 33121007 |
| Title : Novel roles of hepatic lipase and phospholipid transfer protein in VLDL as well as HDL metabolism - van Haperen_2009_Biochim.Biophys.Acta_1791_1031 |
| Author(s) : van Haperen R , Samyn H , van Gent T , Zonneveld AJ , Moerland M , Grosveld F , Jansen H , Dallinga-Thie GM , van Tol A , De Crom R |
| Ref : Biochimica & Biophysica Acta , 1791 :1031 , 2009 |
| Abstract : |
| PubMedSearch : van Haperen_2009_Biochim.Biophys.Acta_1791_1031 |
| PubMedID: 19524061 |
| Title : Down-regulation of hepatic lipase expression by elevation of cAMP in human hepatoma but not adrenocortical cells - van Deursen_2008_Mol.Cell.Endocrinol_294_37 |
| Author(s) : van Deursen D , Botma GJ , Jansen H , Verhoeven AJ |
| Ref : Mol Cell Endocrinol , 294 :37 , 2008 |
| Abstract : |
| PubMedSearch : van Deursen_2008_Mol.Cell.Endocrinol_294_37 |
| PubMedID: 18675312 |
| Title : Glucose increases hepatic lipase expression in HepG2 liver cells through upregulation of upstream stimulatory factors 1 and 2 - van Deursen_2008_Diabetologia_51_2078 |
| Author(s) : van Deursen D , Jansen H , Verhoeven AJ |
| Ref : Diabetologia , 51 :2078 , 2008 |
| Abstract : |
| PubMedSearch : van Deursen_2008_Diabetologia_51_2078 |
| PubMedID: 18758746 |
| Title : High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants - van Acker_2008_Atherosclerosis_200_161 |
| Author(s) : van Acker BA , Botma GJ , Zwinderman AH , Kuivenhoven JA , Dallinga-Thie GM , Sijbrands EJ , Boer JM , Seidell JC , Jukema JW , Kastelein JJ , Jansen H , Verhoeven AJ |
| Ref : Atherosclerosis , 200 :161 , 2008 |
| Abstract : |
| PubMedSearch : van Acker_2008_Atherosclerosis_200_161 |
| PubMedID: 18164013 |
| Title : Comparative genomics and experimental promoter analysis reveal functional liver-specific elements in mammalian hepatic lipase genes - van Deursen_2007_BMC.Genomics_8_99 |
| Author(s) : van Deursen D , Botma GJ , Jansen H , Verhoeven AJ |
| Ref : BMC Genomics , 8 :99 , 2007 |
| Abstract : |
| PubMedSearch : van Deursen_2007_BMC.Genomics_8_99 |
| PubMedID: 17428321 |
| Title : Appraisal of hepatic lipase and lipoprotein lipase activities in mice - Dallinga-Thie_2007_J.Lipid.Res_48_2788 |
| Author(s) : Dallinga-Thie GM , Zonneveld-de Boer AJ , van Vark-van der Zee LC , van Haperen R , van Gent T , Jansen H , De Crom R , van Tol A |
| Ref : J Lipid Res , 48 :2788 , 2007 |
| Abstract : |
| PubMedSearch : Dallinga-Thie_2007_J.Lipid.Res_48_2788 |
| PubMedID: 17872590 |
| Title : Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels - Boekholdt_2006_Clin.Genet_69_263 |
| Author(s) : Boekholdt SM , Souverein OW , Tanck MW , Hovingh GK , Kuivenhoven JA , Peters RI , Jansen H , Schiffers PM , van der Wall EE , Doevendans PA , Reitsma PH , Zwinderman AH , Kastelein JJ , Jukema JW |
| Ref : Clin Genet , 69 :263 , 2006 |
| Abstract : |
| PubMedSearch : Boekholdt_2006_Clin.Genet_69_263 |
| PubMedID: 16542392 |
| Title : Opposite contributions of trunk and leg fat mass with plasma lipase activities: the Hoorn study - Bos_2005_Obes.Res_13_1817 |
| Author(s) : Bos G , Snijder MB , Nijpels G , Dekker JM , Stehouwer CD , Bouter LM , Heine RJ , Jansen H |
| Ref : Obes Res , 13 :1817 , 2005 |
| Abstract : |
| PubMedSearch : Bos_2005_Obes.Res_13_1817 |
| PubMedID: 16286530 |
| Title : Sterol-regulatory-element binding protein inhibits upstream stimulatory factor-stimulated hepatic lipase gene expression - Botma_2005_Atherosclerosis_179_61 |
| Author(s) : Botma GJ , van Deursen D , Vieira D , Van Hoek M , Jansen H , Verhoeven AJ |
| Ref : Atherosclerosis , 179 :61 , 2005 |
| Abstract : |
| PubMedSearch : Botma_2005_Atherosclerosis_179_61 |
| PubMedID: 15721010 |
| Title : Fatty liver in dairy cows post partum is associated with decreased concentration of plasma triacylglycerols and decreased activity of lipoprotein lipase in adipocytes - Van den Top_2005_J.Dairy.Res_72_129 |
| Author(s) : Van den Top AM , van Tol A , Jansen H , Geelen MJ , Beynen AC |
| Ref : J Dairy Res , 72 :129 , 2005 |
| Abstract : |
| PubMedSearch : Van den Top_2005_J.Dairy.Res_72_129 |
| PubMedID: 15909677 |
| Title : Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men - Waterworth_2005_Biochim.Biophys.Acta_1740_375 |
| Author(s) : Waterworth DM , Jansen H , Nicaud V , Humphries SE , Talmud PJ |
| Ref : Biochimica & Biophysica Acta , 1740 :375 , 2005 |
| Abstract : |
| PubMedSearch : Waterworth_2005_Biochim.Biophys.Acta_1740_375 |
| PubMedID: 15949705 |
| Title : Interactions of dietary fat intake and the hepatic lipase -480C-->T polymorphism in determining hepatic lipase activity: the Hoorn Study - Bos_2005_Am.J.Clin.Nutr_81_911 |
| Author(s) : Bos G , Dekker JM , Feskens EJ , Ocke MC , Nijpels G , Stehouwer CD , Bouter LM , Heine RJ , Jansen H |
| Ref : Am J Clin Nutr , 81 :911 , 2005 |
| Abstract : |
| PubMedSearch : Bos_2005_Am.J.Clin.Nutr_81_911 |
| PubMedID: 15817871 |
| Title : The relationship of lipoprotein lipase activity and LDL size is dependent on glucose metabolism in an elderly population: the Hoorn Study - |
| Author(s) : Bos G , Scheffer PG , Vieira D , Dekker JM , Nijpels G , Diamant M , Teerlink T , Stehouwer CD , Bouter LM , Heine RJ , Jansen H |
| Ref : Diabetes Care , 27 :796 , 2004 |
| PubMedID: 14988305 |
| Title : Atorvastatin dose-dependently decreases hepatic lipase activity in type 2 diabetes: effect of sex and the LIPC promoter variant - Berk_2003_Diabetes.Care_26_427 |
| Author(s) : Berk P, II , Hoogerbrugge N , Stolk RP , Bootsma AH , Jansen H |
| Ref : Diabetes Care , 26 :427 , 2003 |
| Abstract : |
| PubMedSearch : Berk_2003_Diabetes.Care_26_427 |
| PubMedID: 12547874 |
| Title : Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor - Botma_2001_Atherosclerosis_154_625 |
| Author(s) : Botma GJ , Verhoeven AJ , Jansen H |
| Ref : Atherosclerosis , 154 :625 , 2001 |
| Abstract : |
| PubMedSearch : Botma_2001_Atherosclerosis_154_625 |
| PubMedID: 11257263 |
| Title : The T allele of the hepatic lipase promoter variant C-480T is associated with increased fasting lipids and HDL and increased preprandial and postprandial LpCIII:B : European Atherosclerosis Research Study (EARS) II - Jansen_1999_Arterioscler.Thromb.Vasc.Biol_19_303 |
| Author(s) : Jansen H , Chu G , Ehnholm C , Dallongeville J , Nicaud V , Talmud PJ |
| Ref : Arterioscler Thromb Vasc Biol , 19 :303 , 1999 |
| Abstract : |
| PubMedSearch : Jansen_1999_Arterioscler.Thromb.Vasc.Biol_19_303 |
| PubMedID: 9974411 |
| Title : Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins - Henderson_1999_J.Lipid.Res_40_735 |
| Author(s) : Henderson HE , Kastelein JJ , Zwinderman AH , Gagne E , Jukema JW , Reymer PW , Groenemeyer BE , Lie KI , Bruschke AV , Hayden MR , Jansen H |
| Ref : J Lipid Res , 40 :735 , 1999 |
| Abstract : |
| PubMedSearch : Henderson_1999_J.Lipid.Res_40_735 |
| PubMedID: 10191298 |
| Title : The Asn9 variant of lipoprotein lipase is associated with the -93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group - Kastelein_1998_Clin.Genet_53_27 |
| Author(s) : Kastelein JJ , Groenemeyer BE , Hallman DM , Henderson H , Reymer PW , Gagne SE , Jansen H , Seidell JC , Kromhout D , Jukema JW , Bruschke AV , Boerwinkle E , Hayden MR |
| Ref : Clin Genet , 53 :27 , 1998 |
| Abstract : |
| PubMedSearch : Kastelein_1998_Clin.Genet_53_27 |
| PubMedID: 9550358 |
| Title : Role of lipoprotein lipases in postprandial lipid metabolism - Jansen_1998_Atherosclerosis_141 Suppl 1_S31 |
| Author(s) : Jansen H , Breedveld B , Schoonderwoerd K |
| Ref : Atherosclerosis , 141 Suppl 1 :S31 , 1998 |
| Abstract : |
| PubMedSearch : Jansen_1998_Atherosclerosis_141 Suppl 1_S31 |
| PubMedID: 9888639 |
| Title : Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients - Jansen_1997_Arterioscler.Thromb.Vasc.Biol_17_2837 |
| Author(s) : Jansen H , Verhoeven AJ , Weeks L , Kastelein JJ , Halley DJ , van den Ouweland A , Jukema JW , Seidell JC , Birkenhager JC |
| Ref : Arterioscler Thromb Vasc Biol , 17 :2837 , 1997 |
| Abstract : |
| PubMedSearch : Jansen_1997_Arterioscler.Thromb.Vasc.Biol_17_2837 |
| PubMedID: 9409263 |
| Title : Genetic variant showing a positive interaction with beta-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene. REGRESS Study Group - Groenemeijer_1997_Circulation_95_2628 |
| Author(s) : Groenemeijer BE , Hallman MD , Reymer PW , Gagne E , Kuivenhoven JA , Bruin T , Jansen H , Lie KI , Bruschke AV , Boerwinkle E , Hayden MR , Kastelein JJ |
| Ref : Circulation , 95 :2628 , 1997 |
| Abstract : |
| PubMedSearch : Groenemeijer_1997_Circulation_95_2628 |
| PubMedID: 9193431 |
| Title : The rat hepatic lipase gene is expressed into two different proteins in liver, adrenals and ovaries - Verhoeven_1996_Z.Gastroenterol_3_54 |
| Author(s) : Verhoeven AJ , Jansen H |
| Ref : Z Gastroenterol , 3 :54 , 1996 |
| Abstract : |
| PubMedSearch : Verhoeven_1996_Z.Gastroenterol_3_54 |
| PubMedID: 8767462 |
| Title : Functional molecular mass of rat hepatic lipase in liver, adrenal gland and ovary is different - Schoonderwoerd_1996_Biochem.J_318 ( Pt 2)_463 |
| Author(s) : Schoonderwoerd K , Hom ML , Luthjens LH , Vieira van Bruggen D , Jansen H |
| Ref : Biochemical Journal , 318 ( Pt 2) :463 , 1996 |
| Abstract : |
| PubMedSearch : Schoonderwoerd_1996_Biochem.J_318 ( Pt 2)_463 |
| PubMedID: 8809034 |
| Title : A lipoprotein lipase mutation (Asn291Ser) is associated with reduced HDL cholesterol levels in premature atherosclerosis - Reymer_1995_Nat.Genet_10_28 |
| Author(s) : Reymer PW , Gagne E , Groenemeyer BE , Zhang H , Forsyth I , Jansen H , Seidell JC , Kromhout D , Lie KE , Kastelein J , et al. |
| Ref : Nat Genet , 10 :28 , 1995 |
| Abstract : |
| PubMedSearch : Reymer_1995_Nat.Genet_10_28 |
| PubMedID: 7647785 |
| Gene_locus related to this paper: human-LPL |
| Title : Hepatic lipase mRNA is expressed in rat and human steroidogenic organs - Verhoeven_1994_Biochim.Biophys.Acta_1211_121 |
| Author(s) : Verhoeven AJ , Jansen H |
| Ref : Biochimica & Biophysica Acta , 1211 :121 , 1994 |
| Abstract : |
| PubMedSearch : Verhoeven_1994_Biochim.Biophys.Acta_1211_121 |
| PubMedID: 8123676 |
| Title : A compound heterozygote for lipoprotein lipase deficiency, Val69-->\;Leu and Gly188-->\;Glu: correlation between in vitro LPL activity and clinical expression - Bruin_1994_J.Lipid.Res_35_438 |
| Author(s) : Bruin T , Tuzgol S , Mulder WJ , van den Ende AE , Jansen H , Hayden MR , Kastelein JJ |
| Ref : J Lipid Res , 35 :438 , 1994 |
| Abstract : |
| PubMedSearch : Bruin_1994_J.Lipid.Res_35_438 |
| PubMedID: 7912254 |
| Title : Hepatic lipase gene is transcribed in rat adrenals into a truncated mRNA - Verhoeven_1994_J.Lipid.Res_35_966 |
| Author(s) : Verhoeven AJ , Carling D , Jansen H |
| Ref : J Lipid Res , 35 :966 , 1994 |
| Abstract : |
| PubMedSearch : Verhoeven_1994_J.Lipid.Res_35_966 |
| PubMedID: 7521385 |
| Title : Functional role of N-linked glycosylation in human hepatic lipase: asparagine-56 is important for both enzyme activity and secretion - Wolle_1993_J.Lipid.Res_34_2169 |
| Author(s) : Wolle J , Jansen H , Smith LC , Chan L |
| Ref : J Lipid Res , 34 :2169 , 1993 |
| Abstract : |
| PubMedSearch : Wolle_1993_J.Lipid.Res_34_2169 |
| PubMedID: 8301235 |
| Title : Growth hormone normalizes hepatic lipase in hypothyroid rat liver - Hoogerbrugge_1993_Metabolism_42_669 |
| Author(s) : Hoogerbrugge N , Jansen H , Staels B , Seip MJ , Birkenhager JC |
| Ref : Metabolism , 42 :669 , 1993 |
| Abstract : |
| PubMedSearch : Hoogerbrugge_1993_Metabolism_42_669 |
| PubMedID: 8510508 |
| Title : Properties of binding of lipases to non-parenchymal rat liver cells - Jansen_1980_Biochim.Biophys.Acta_619_119 |
| Author(s) : Jansen H , van Berkel TJ , Hulsmann WC |
| Ref : Biochimica & Biophysica Acta , 619 :119 , 1980 |
| Abstract : |
| PubMedSearch : Jansen_1980_Biochim.Biophys.Acta_619_119 |
| PubMedID: 7417461 |