Full name : Kitz Richard J
First name : Richard J
Mail : Department of Anaesthesia, .Harvard Medical School, Massachusetts General Hospital, Boston, Mass 02114
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Country : USA
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Richard J. Kitz was born in Oshkosh, Wisconsin, Oct. 25, 1929 September 19, 2017 Dr.Kitz led the Massachussetts General Department of Anesthesia, Critical Care and Pain Medicine from 1969 to 1994. Irwin B. Wilson and Richard J. Kitz described the inhibition of acetylcholinesterase in two steps by covalently acting molecules which rapidly and reversibly bind to the active site of the enzyme. Next, the reversible complex undergoes covalent fixation at a characteristic rate
| Title : Actions at neuromuscular and esteratic cholinoceptive sites of some phenylene diacryloyl bis-cholinium esters - |
| Author(s) : Savarese JJ , Ginsburg S , Braswell L , Kitz RJ |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 208 :436 , 1979 |
| PubMedID: 430363 |
| Title : Actions at neuromuscular and esteratic cholinoceptive sites of some phenylene diacryloyl bis-cholinium esters - |
| Author(s) : Savarese JJ , Ginsburg S , Braswell L , Kitz RJ |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 208 :436 , 1979 |
| PubMedID: 430363 |
| Title : Actions at neuromuscular and esteratic cholinoceptive sites of some phenylene diacryloyl bis-cholinium esters - |
| Author(s) : Savarese JJ , Ginsburg S , Braswell L , Kitz RJ |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 208 :436 , 1979 |
| PubMedID: 430363 |
| Title : The effect in vitro of volatile anesthetics on the activity of cholinesterases - |
| Author(s) : Braswell LM , Kitz RJ |
| Ref : Journal of Neurochemistry , 29 :665 , 1977 |
| PubMedID: 22584 |
| Title : The effect in vitro of volatile anesthetics on the activity of cholinesterases - |
| Author(s) : Braswell LM , Kitz RJ |
| Ref : Journal of Neurochemistry , 29 :665 , 1977 |
| PubMedID: 22584 |
| Title : The effect in vitro of volatile anesthetics on the activity of cholinesterases - |
| Author(s) : Braswell LM , Kitz RJ |
| Ref : Journal of Neurochemistry , 29 :665 , 1977 |
| PubMedID: 22584 |
| Title : Mode of action of trichloroethylene on squid axon membranes - Shrivastav_1976_J.Pharmacol.Exp.Ther_199_179 |
| Author(s) : Shrivastav BB , Narahashi T , Kitz RJ , Roberts JD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 199 :179 , 1976 |
| Abstract : |
| PubMedSearch : Shrivastav_1976_J.Pharmacol.Exp.Ther_199_179 |
| PubMedID: 978477 |
| Title : Mode of action of trichloroethylene on squid axon membranes - Shrivastav_1976_J.Pharmacol.Exp.Ther_199_179 |
| Author(s) : Shrivastav BB , Narahashi T , Kitz RJ , Roberts JD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 199 :179 , 1976 |
| Abstract : |
| PubMedSearch : Shrivastav_1976_J.Pharmacol.Exp.Ther_199_179 |
| PubMedID: 978477 |
| Title : Mode of action of trichloroethylene on squid axon membranes - Shrivastav_1976_J.Pharmacol.Exp.Ther_199_179 |
| Author(s) : Shrivastav BB , Narahashi T , Kitz RJ , Roberts JD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 199 :179 , 1976 |
| Abstract : |
| PubMedSearch : Shrivastav_1976_J.Pharmacol.Exp.Ther_199_179 |
| PubMedID: 978477 |
| Title : Decamethonium and serum potassium in man - Fahmy_1975_Anesthesiology_42_692 |
| Author(s) : Fahmy NR , Gissen AJ , Savarese JJ , Kitz RJ |
| Ref : Anesthesiology , 42 :692 , 1975 |
| Abstract : |
| PubMedSearch : Fahmy_1975_Anesthesiology_42_692 |
| PubMedID: 1130739 |
| Title : The effect of tubocurarine on indirectly elicited train-of-four muscle response and respiratory measurements in humans - Ali_1975_Br.J.Anaesth_47_570 |
| Author(s) : Ali HH , Wilson RS , Savarese JJ , Kitz RJ |
| Ref : British Journal of Anaesthesia , 47 :570 , 1975 |
| Abstract : |
| PubMedSearch : Ali_1975_Br.J.Anaesth_47_570 |
| PubMedID: 1138775 |
| Title : The effect of tubocurarine on indirectly elicited train-of-four muscle response and respiratory measurements in humans - Ali_1975_Br.J.Anaesth_47_570 |
| Author(s) : Ali HH , Wilson RS , Savarese JJ , Kitz RJ |
| Ref : British Journal of Anaesthesia , 47 :570 , 1975 |
| Abstract : |
| PubMedSearch : Ali_1975_Br.J.Anaesth_47_570 |
| PubMedID: 1138775 |
| Title : Decamethonium and serum potassium in man - Fahmy_1975_Anesthesiology_42_692 |
| Author(s) : Fahmy NR , Gissen AJ , Savarese JJ , Kitz RJ |
| Ref : Anesthesiology , 42 :692 , 1975 |
| Abstract : |
| PubMedSearch : Fahmy_1975_Anesthesiology_42_692 |
| PubMedID: 1130739 |
| Title : Decamethonium and serum potassium in man - Fahmy_1975_Anesthesiology_42_692 |
| Author(s) : Fahmy NR , Gissen AJ , Savarese JJ , Kitz RJ |
| Ref : Anesthesiology , 42 :692 , 1975 |
| Abstract : |
| PubMedSearch : Fahmy_1975_Anesthesiology_42_692 |
| PubMedID: 1130739 |
| Title : Does clinical anesthesia need new neuromuscular blocking agents? - |
| Author(s) : Savarese JJ , Kitz RJ |
| Ref : Anesthesiology , 42 :236 , 1975 |
| PubMedID: 123132 |
| Title : Does clinical anesthesia need new neuromuscular blocking agents? - |
| Author(s) : Savarese JJ , Kitz RJ |
| Ref : Anesthesiology , 42 :236 , 1975 |
| PubMedID: 123132 |
| Title : Does clinical anesthesia need new neuromuscular blocking agents? - |
| Author(s) : Savarese JJ , Kitz RJ |
| Ref : Anesthesiology , 42 :236 , 1975 |
| PubMedID: 123132 |
| Title : The effect of tubocurarine on indirectly elicited train-of-four muscle response and respiratory measurements in humans - Ali_1975_Br.J.Anaesth_47_570 |
| Author(s) : Ali HH , Wilson RS , Savarese JJ , Kitz RJ |
| Ref : British Journal of Anaesthesia , 47 :570 , 1975 |
| Abstract : |
| PubMedSearch : Ali_1975_Br.J.Anaesth_47_570 |
| PubMedID: 1138775 |
| Title : The pharmacology of new short-acting nondepolarizing ester neuromuscular blocking agents: clinical implications - |
| Author(s) : Savarese JJ , Ginsburg S , Lee SM , Kitz RJ |
| Ref : Anesthesia & Analgesia , 52 :982 , 1973 |
| PubMedID: 4271295 |
| Title : The quest for a short-acting nondepolarizing neuromuscular blocking agent - |
| Author(s) : Savarese JJ , Kitz RJ |
| Ref : Acta Anaesthesiologica Scandinavica Supplementum , 53 :43 , 1973 |
| PubMedID: 4139860 |
| Title : The pharmacology of new short-acting nondepolarizing ester neuromuscular blocking agents: clinical implications - |
| Author(s) : Savarese JJ , Ginsburg S , Lee SM , Kitz RJ |
| Ref : Anesthesia & Analgesia , 52 :982 , 1973 |
| PubMedID: 4271295 |
| Title : The quest for a short-acting nondepolarizing neuromuscular blocking agent - |
| Author(s) : Savarese JJ , Kitz RJ |
| Ref : Acta Anaesthesiologica Scandinavica Supplementum , 53 :43 , 1973 |
| PubMedID: 4139860 |
| Title : The pharmacology of new short-acting nondepolarizing ester neuromuscular blocking agents: clinical implications - |
| Author(s) : Savarese JJ , Ginsburg S , Lee SM , Kitz RJ |
| Ref : Anesthesia & Analgesia , 52 :982 , 1973 |
| PubMedID: 4271295 |
| Title : The quest for a short-acting nondepolarizing neuromuscular blocking agent - |
| Author(s) : Savarese JJ , Kitz RJ |
| Ref : Acta Anaesthesiologica Scandinavica Supplementum , 53 :43 , 1973 |
| PubMedID: 4139860 |
| Title : The effects of pH on penetration and action of procaine 14C, atropine 3H, n-butanol 14C and halothane 14C in single giant axons of the squid - |
| Author(s) : Dettbarn WD , Heilbronn E , Hoskin FC , Kitz RJ |
| Ref : Neuropharmacology , 11 :727 , 1972 |
| PubMedID: 4670599 |
| Title : The effects of pH on penetration and action of procaine 14C, atropine 3H, n-butanol 14C and halothane 14C in single giant axons of the squid - |
| Author(s) : Dettbarn WD , Heilbronn E , Hoskin FC , Kitz RJ |
| Ref : Neuropharmacology , 11 :727 , 1972 |
| PubMedID: 4670599 |
| Title : The effects of pH on penetration and action of procaine 14C, atropine 3H, n-butanol 14C and halothane 14C in single giant axons of the squid - |
| Author(s) : Dettbarn WD , Heilbronn E , Hoskin FC , Kitz RJ |
| Ref : Neuropharmacology , 11 :727 , 1972 |
| PubMedID: 4670599 |
| Title : Neuromuscular blocking activity of a new series of quaternary N-substituted choline esters - Ginsburg_1971_Br.J.Pharmacol_43_107 |
| Author(s) : Ginsburg S , Kitz RJ , Savarese JJ |
| Ref : British Journal of Pharmacology , 43 :107 , 1971 |
| Abstract : |
| PubMedSearch : Ginsburg_1971_Br.J.Pharmacol_43_107 |
| PubMedID: 4257628 |
| Title : Neuromuscular blocking activity of a new series of quaternary N-substituted choline esters - Ginsburg_1971_Br.J.Pharmacol_43_107 |
| Author(s) : Ginsburg S , Kitz RJ , Savarese JJ |
| Ref : British Journal of Pharmacology , 43 :107 , 1971 |
| Abstract : |
| PubMedSearch : Ginsburg_1971_Br.J.Pharmacol_43_107 |
| PubMedID: 4257628 |
| Title : Neuromuscular blocking activity of a new series of quaternary N-substituted choline esters - Ginsburg_1971_Br.J.Pharmacol_43_107 |
| Author(s) : Ginsburg S , Kitz RJ , Savarese JJ |
| Ref : British Journal of Pharmacology , 43 :107 , 1971 |
| Abstract : |
| PubMedSearch : Ginsburg_1971_Br.J.Pharmacol_43_107 |
| PubMedID: 4257628 |
| Title : On the question, Is acetylcholinesterase an allosteric protein? - |
| Author(s) : Kitz RJ , Braswell LM , Ginsburg S |
| Ref : Molecular Pharmacology , 6 :108 , 1970 |
| PubMedID: 5418229 |
| Title : On the question, Is acetylcholinesterase an allosteric protein? - |
| Author(s) : Kitz RJ , Braswell LM , Ginsburg S |
| Ref : Molecular Pharmacology , 6 :108 , 1970 |
| PubMedID: 5418229 |
| Title : On the question, Is acetylcholinesterase an allosteric protein? - |
| Author(s) : Kitz RJ , Braswell LM , Ginsburg S |
| Ref : Molecular Pharmacology , 6 :108 , 1970 |
| PubMedID: 5418229 |
| Title : Acetylcholinesterase: some evidence for conformational changes and allosteric interactions - |
| Author(s) : Kitz RJ , Braswell LM |
| Ref : Drugs and Cholinergic Mechanisms in the CNS :465 , 1970 |
| PubMedID: |
| Title : Acetylcholinesterase: some evidence for conformational changes and allosteric interactions - |
| Author(s) : Kitz RJ , Braswell LM |
| Ref : Drugs and Cholinergic Mechanisms in the CNS :465 , 1970 |
| PubMedID: |
| Title : Acetylcholinesterase: some evidence for conformational changes and allosteric interactions - |
| Author(s) : Kitz RJ , Braswell LM |
| Ref : Drugs and Cholinergic Mechanisms in the CNS :465 , 1970 |
| PubMedID: |
| Title : A study in vitro of new short-acting, non-depolarizing neuromuscular blocking agents - |
| Author(s) : Kitz RJ , Karis JH , Ginsburg S |
| Ref : Biochemical Pharmacology , 18 :871 , 1969 |
| PubMedID: 5788524 |
| Title : The reaction of acetylcholinesterase with methanesulfonyl esters of quaternary quinolinium compounds - |
| Author(s) : Ryan JF , Ginsburg S , Kitz RJ |
| Ref : Biochemical Pharmacology , 18 :269 , 1969 |
| PubMedID: 5778146 |
| Title : A study in vitro of new short-acting, non-depolarizing neuromuscular blocking agents - |
| Author(s) : Kitz RJ , Karis JH , Ginsburg S |
| Ref : Biochemical Pharmacology , 18 :871 , 1969 |
| PubMedID: 5788524 |
| Title : A study in vitro of new short-acting, non-depolarizing neuromuscular blocking agents - |
| Author(s) : Kitz RJ , Karis JH , Ginsburg S |
| Ref : Biochemical Pharmacology , 18 :871 , 1969 |
| PubMedID: 5788524 |
| Title : The reaction of acetylcholinesterase with methanesulfonyl esters of quaternary quinolinium compounds - |
| Author(s) : Ryan JF , Ginsburg S , Kitz RJ |
| Ref : Biochemical Pharmacology , 18 :269 , 1969 |
| PubMedID: 5778146 |
| Title : The reaction of acetylcholinesterase with methanesulfonyl esters of quaternary quinolinium compounds - |
| Author(s) : Ryan JF , Ginsburg S , Kitz RJ |
| Ref : Biochemical Pharmacology , 18 :269 , 1969 |
| PubMedID: 5778146 |
| Title : Effect of flaxedil on inhibition and reactivation of acetylcholinesterase - |
| Author(s) : Kitz RJ , Braswell LT |
| Ref : Federation Proceedings , 27 :407 , 1968 |
| PubMedID: |
| Title : The reaction of acetylcholinesterase (ACHE) with some quaternary hydroxy aminophenols - |
| Author(s) : Kitz RJ , Ginsburg S |
| Ref : Biochemical Pharmacology , 17 :525 , 1968 |
| PubMedID: 5690300 |
| Title : Conformational changes of acetylcholinesterase - |
| Author(s) : Kitz RJ , Kremzner LT |
| Ref : Molecular Pharmacology , 4 :104 , 1968 |
| PubMedID: 4295904 |
| Title : Effect of flaxedil on inhibition and reactivation of acetylcholinesterase - |
| Author(s) : Kitz RJ , Braswell LT |
| Ref : Federation Proceedings , 27 :407 , 1968 |
| PubMedID: |
| Title : The reaction of acetylcholinesterase (ACHE) with some quaternary hydroxy aminophenols - |
| Author(s) : Kitz RJ , Ginsburg S |
| Ref : Biochemical Pharmacology , 17 :525 , 1968 |
| PubMedID: 5690300 |
| Title : Conformational changes of acetylcholinesterase - |
| Author(s) : Kitz RJ , Kremzner LT |
| Ref : Molecular Pharmacology , 4 :104 , 1968 |
| PubMedID: 4295904 |
| Title : Effect of flaxedil on inhibition and reactivation of acetylcholinesterase - |
| Author(s) : Kitz RJ , Braswell LT |
| Ref : Federation Proceedings , 27 :407 , 1968 |
| PubMedID: |
| Title : The reaction of acetylcholinesterase (ACHE) with some quaternary hydroxy aminophenols - |
| Author(s) : Kitz RJ , Ginsburg S |
| Ref : Biochemical Pharmacology , 17 :525 , 1968 |
| PubMedID: 5690300 |
| Title : Conformational changes of acetylcholinesterase - |
| Author(s) : Kitz RJ , Kremzner LT |
| Ref : Molecular Pharmacology , 4 :104 , 1968 |
| PubMedID: 4295904 |
| Title : The reaction of acetylcholinesterase with diethylphosphoryl esters of quaternary and tertiary aminophenols - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Molecular Pharmacology , 3 :225 , 1967 |
| PubMedID: 6037683 |
| Title : The reaction of acetylcholinesterase with O-dimethylcarbamyl esters of quaternary quinolinium compounds - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Biochemical Pharmacology , 16 :2201 , 1967 |
| PubMedID: 6076610 |
| Title : The reaction of acetylcholinesterase with diethylphosphoryl esters of quaternary and tertiary aminophenols - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Molecular Pharmacology , 3 :225 , 1967 |
| PubMedID: 6037683 |
| Title : The reaction of acetylcholinesterase with O-dimethylcarbamyl esters of quaternary quinolinium compounds - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Biochemical Pharmacology , 16 :2201 , 1967 |
| PubMedID: 6076610 |
| Title : The reaction of acetylcholinesterase with diethylphosphoryl esters of quaternary and tertiary aminophenols - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Molecular Pharmacology , 3 :225 , 1967 |
| PubMedID: 6037683 |
| Title : The reaction of acetylcholinesterase with O-dimethylcarbamyl esters of quaternary quinolinium compounds - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Biochemical Pharmacology , 16 :2201 , 1967 |
| PubMedID: 6076610 |
| Title : A quantitative technique for the evaluation of peripheral neuromuscular blockade in man - |
| Author(s) : Nemazie AS , Kitz RJ |
| Ref : Anesthesiology , 28 :215 , 1967 |
| PubMedID: 6017431 |
| Title : A partial purification and characterization of the acetylcholinesterase of human brain - |
| Author(s) : Kremzner LT , Kitz RJ , Ginsburg S |
| Ref : Federation Proceedings , 26 :296 , 1967 |
| PubMedID: |
| Title : A partial purification and characterization of the acetylcholinesterase of human brain - |
| Author(s) : Kremzner LT , Kitz RJ , Ginsburg S |
| Ref : Federation Proceedings , 26 :296 , 1967 |
| PubMedID: |
| Title : A quantitative technique for the evaluation of peripheral neuromuscular blockade in man - |
| Author(s) : Nemazie AS , Kitz RJ |
| Ref : Anesthesiology , 28 :215 , 1967 |
| PubMedID: 6017431 |
| Title : A partial purification and characterization of the acetylcholinesterase of human brain - |
| Author(s) : Kremzner LT , Kitz RJ , Ginsburg S |
| Ref : Federation Proceedings , 26 :296 , 1967 |
| PubMedID: |
| Title : A quantitative technique for the evaluation of peripheral neuromuscular blockade in man - |
| Author(s) : Nemazie AS , Kitz RJ |
| Ref : Anesthesiology , 28 :215 , 1967 |
| PubMedID: 6017431 |
| Title : O-diethyl phosphoryl esters of quaternary and tertiary aminophenols - |
| Author(s) : Ginsburg S , Kitz RJ , Wilson IB |
| Ref : Journal of Medicinal Chemistry , 9 :632 , 1966 |
| PubMedID: 5968040 |
| Title : O-diethyl phosphoryl esters of quaternary and tertiary aminophenols - |
| Author(s) : Ginsburg S , Kitz RJ , Wilson IB |
| Ref : Journal of Medicinal Chemistry , 9 :632 , 1966 |
| PubMedID: 5968040 |
| Title : O-diethyl phosphoryl esters of quaternary and tertiary aminophenols - |
| Author(s) : Ginsburg S , Kitz RJ , Wilson IB |
| Ref : Journal of Medicinal Chemistry , 9 :632 , 1966 |
| PubMedID: 5968040 |
| Title : Activity-structure relationships in the reactivation of diethylphosphoryl acetylcholinesterase by phenyl-1-methyl pyridinium ketoximes - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Biochemical Pharmacology , 14 :1471 , 1965 |
| PubMedID: 5865872 |
| Title : Activity-structure relationships in the reactivation of diethylphosphoryl acetylcholinesterase by phenyl-1-methyl pyridinium ketoximes - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Biochemical Pharmacology , 14 :1471 , 1965 |
| PubMedID: 5865872 |
| Title : Activity-structure relationships in the reactivation of diethylphosphoryl acetylcholinesterase by phenyl-1-methyl pyridinium ketoximes - |
| Author(s) : Kitz RJ , Ginsburg S , Wilson IB |
| Ref : Biochemical Pharmacology , 14 :1471 , 1965 |
| PubMedID: 5865872 |