Full name : Holmstedt Bo
First name : Bo
Mail : Toxicology Unit, Institute of Environmental Medicine Karolinska Institute
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City :
Country : Sweden
Email :
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Website : \/\/www.eurotox.com\/bhmf\/
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Comment
Bo Holmstedt was born 1919 in the southern part of Sweden, and died in 2002. Bo Holmstedt studied medicine at the Karolinska Institute. He became full professor in toxicology at the Karolinska Institute in 1964. He studied organophosphate compounds. He described the synthesis of tabun. He developed a histochemical method to reveal cholinergic nerves. During the Alpha Helix expedition to the Amazons in 1967, he and his collaborators identified hallucinogens, 5-metoxy-N, -carboline-alkaloids, used by different South and American Indian tribes. A tribute to his work was given at the 11th international symposium on cholinergic mechanisms (St Moritz) in 2002. and an obituary paper by Malmfos T.
| Title : Chemical methods for the determination of acetylcholine - |
| Author(s) : Holmstedt B |
| Ref : Life Sciences , 58 :1917 , 1996 |
| PubMedID: 8637419 |
| Title : Intoxications with anticholinesterases: effect of different combinations of antidotes on the dynamics of acetylcholine in mouse brain - Nordgren_1992_Pharmacol.Toxicol_70_384 |
| Author(s) : Nordgren I , Karlen B , Kimland M , Palmer L , Holmstedt B |
| Ref : Pharmacol Toxicol , 70 :384 , 1992 |
| Abstract : |
| PubMedSearch : Nordgren_1992_Pharmacol.Toxicol_70_384 |
| PubMedID: 1608928 |
| Title : Poster: Mechanism of action of the protecting effect of combinations of antidotes in intoxications with anticholinesterases - |
| Author(s) : Nordgren I , Karlen B , Kimland M , Palmer L , Holmstedt B |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :301 , 1991 |
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| Title : Acetylcholine Turnover in Mouse Brain: Influence of Cholinesterase Inhibitors - |
| Author(s) : Karlen B , Lundgren G , Lundin J , Holmstedt B |
| Ref : Advances in Behavioral Biology , 30 :781 , 1986 |
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| Title : Analysis of succinylcholine in tissues and body fluids by ion-pair extraction and gas chromatography-mass spectrometry - Nordgren_1983_Arch.Toxicol.Suppl_6_339 |
| Author(s) : Nordgren I , Forney RB, Jr. , Carroll FT , Holmstedt B , Jaderholm-Ek I , Pettersson BM |
| Ref : Archives of Toxicology Suppl , 6 :339 , 1983 |
| Abstract : |
| PubMedSearch : Nordgren_1983_Arch.Toxicol.Suppl_6_339 |
| PubMedID: 6578742 |
| Title : Extraction, identification and quantitation of succinylcholine in embalmed tissue - Forney_1982_J.Anal.Toxicol_6_115 |
| Author(s) : Forney RB, Jr. , Carroll FT , Nordgren IK , Pettersson BM , Holmstedt B |
| Ref : J Anal Toxicol , 6 :115 , 1982 |
| Abstract : |
| PubMedSearch : Forney_1982_J.Anal.Toxicol_6_115 |
| PubMedID: 7109551 |
| Title : Metrifonate and dichlorvos: theoretical and practical aspects. History and scope of the conference - |
| Author(s) : Aldridge WN , Holmstedt B |
| Ref : Acta Pharmacologica et Toxicologica (Copenh) , 49 Suppl 5 :3 , 1981 |
| PubMedID: 7046344 |
| Title : Subcellular fractionation of cat submandibular gland: comparative studies on the distribution of acetylcholine and vasoactive intestinal polypeptide (VIP) - |
| Author(s) : Lundberg JM , Fried G , Fahrenkrug J , Holmstedt B , Hokfelt T , Lagercrantz H , Lundgren G , Anggard A |
| Ref : Neuroscience , 6 :1001 , 1981 |
| PubMedID: 7279209 |
| Title : Effect of Atropine on Acetylcholine Metabolism in the Mouse Brain - |
| Author(s) : Karlen B , Lundgren G , Miyata T , Lundin J , Holmstedt B |
| Ref : Advances in Behavioral Biology , 24 :643 , 1978 |
| PubMedID: |
| Title : Effect of occupational exposure to organophosphorus insecticides on neuromuscular function - Stalberg_1978_Scand.J.Work.Environ.Health_4_255 |
| Author(s) : Stalberg E , Hilton-Brown P , Kolmodin-Hedman B , Holmstedt B , Augustinsson KB |
| Ref : Scandinavian Journal of Work, Environment & Health , 4 :255 , 1978 |
| Abstract : |
| PubMedSearch : Stalberg_1978_Scand.J.Work.Environ.Health_4_255 |
| PubMedID: 212825 |
| Title : Acetylcholine and choline in mouse brain--influence of peripherally acting cholinergic drugs - |
| Author(s) : Lundgren G , Karlen B , Holmstedt B |
| Ref : Biochemical Pharmacology , 26 :1607 , 1977 |
| PubMedID: 901579 |
| Title : Pages from the history of research on cholinergic mechanisms - |
| Author(s) : Holmstedt B |
| Ref : Cholinergic.Mechanisms, Raven Press :1 , 1975 |
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| Title : Acetylcholine turnover in mouse brain in vivo studied with a mass fragmentographic technique - |
| Author(s) : Karlen B , Lundgren G , Lundholm B , Nordgren I , Holmstedt B |
| Ref : Cholinergic.Mechanisms, Raven Press :99 , 1975 |
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| Title : Relationship between acetylcholine and cholinesterase activity in the brain following an organophosphorus inhibitor - |
| Author(s) : Holmstedt B , Harkonen M , Lundgren G , Sundwall A , Sundwali A |
| Ref : Biochemical Pharmacology , 16 :404 , 1967 |
| PubMedID: 6029922 |
| Title : Determination of cholinesterase in blood samples dried on filter-paper and its practical application - |
| Author(s) : Augustinsson KB , Holmstedt B |
| Ref : Scand J Clin Lab Invest , 17 :573 , 1965 |
| PubMedID: 5858749 |
| Title : Tremorine and oxotremorine effects on acetlcholinesterase and choline acetylase from rat brain - |
| Author(s) : Holmstedt B , Lundgren G , Schuberth J , Sundwall A |
| Ref : Biochemical Pharmacology , 14 :189 , 1965 |
| PubMedID: 14332469 |
| Title : Structure-activity relationships of the organophosphorus anticholinesterase agents - |
| Author(s) : Holmstedt B |
| Ref : Handbook of Experimental Pharmacology , 15 :428 , 1963 |
| PubMedID: |
| Title : Anticholinesterase agents - |
| Author(s) : Koelle GB , Volle RB , Holmstedt B , Karczmar AG , O'Brien RD |
| Ref : Science , 141 :63 , 1963 |
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| Title : Tremorine and atropine effects on rain acetylcholine - |
| Author(s) : Holmstedt B , Lundgren G , Sundwall A |
| Ref : Life Sciences , 10 :731 , 1963 |
| PubMedID: 14076593 |
| Title : Some principles about histochemistry of cholinesterase with special reference to the thiocholine method - |
| Author(s) : Holmstedt B , Sjoqvist F |
| Ref : Bibliotheca Anat , 2 :1 , 1961 |
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| Title : Effects of sarin in the anesthetized and unanesthetized dog following inhalation, percutaneous absorption and intravenous infusion - |
| Author(s) : Fredriksson T , Hansson GH , Holmstedt B |
| Ref : Archives Internationales de Pharmacodynamie et de Therapie , 126 :228 , 1960 |
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| Title : Pharmacology of organophosphorus cholinesterase inhibitors - |
| Author(s) : Holmstedt B |
| Ref : Pharmacological Reviews , 11 :567 , 1959 |
| PubMedID: |
| Title : The pathology of experimental cholinesterase-inhibitor poisoning - |
| Author(s) : Holmstedt B , Krook L , Rooney JR |
| Ref : Acta Pharmacologica et Toxicologica (Copenh) , 13 :337 , 1957 |
| PubMedID: |
| Title : A modification of the thiocholine method for the determination of cholinesterase. I. Biochemical evaluation of selective inhibitors - |
| Author(s) : Holmstedt B |
| Ref : Acta Physiologica Scandinavica , 40 :322 , 1957 |
| PubMedID: |
| Title : A modification of the thiocholine method for the determination of cholinesterase. II. Histochemical application - |
| Author(s) : Holmstedt B |
| Ref : Acta Physiologica Scandinavica , 40 :331 , 1957 |
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| Title : Some considerations regarding the nomenclature of organic phosphorus compounds - |
| Author(s) : Larsson L , Holmstedt B , Tjus E |
| Ref : Acta Chemica Scandinavica , 8 :1563 , 1954 |
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| Title : Effect of phenothiazine derivatives against poisoning by irreversible cholinesterase inhibitor dimethylamido-ethoxyphosphoryl cyanide (tabun) - |
| Author(s) : Dahlbom R , Diamant H , Edlund T , Ekstrand T , Holmstedt B |
| Ref : Acta Pharmacologica et Toxicologica (Copenh) , 9 :163 , 1953 |
| PubMedID: 13079852 |
| Title : Synthesis and pharmacology of dimethylamidoethoxyphosphoryl cyanide (tabun) together with a description of some allied anticholinesterase compounds contamina the N-P bond - |
| Author(s) : Holmstedt B |
| Ref : Acta Physiologica Scandinavica , 25 :11 , 1951 |
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