McDonough JH

General

Full name : McDonough John H

First name : John H

Mail : Pharmacology Branch, Research Division, US Army Medical Research Institute of Chemical Defense, 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010-5400

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Country : USA

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References (26)

Title : Screening for Efficacious Anticonvulsants and Neuroprotectants in Delayed Treatment Models of Organophosphate-induced Status Epilepticus - Barker_2020_Neurosci_425_280
Author(s) : Barker BS , Spampanato J , McCarren HS , Smolik M , Jackson CE , Hornung EN , Yeung DT , Dudek FE , McDonough JH
Ref : Neuroscience , 425 :280 , 2020
Abstract :
PubMedSearch : Barker_2020_Neurosci_425_280
PubMedID: 31783100

Title : Validating a model of benzodiazepine refractory nerve agent-induced status epilepticus by evaluating the anticonvulsant and neuroprotective effects of scopolamine, memantine, and phenobarbital - Jackson_2019_J.Pharmacol.Toxicol.Methods_97_1
Author(s) : Jackson C , Ardinger C , Winter KM , McDonough JH , McCarren HS
Ref : Journal of Pharmacological & Toxicological Methods , 97 :1 , 2019
Abstract :
PubMedSearch : Jackson_2019_J.Pharmacol.Toxicol.Methods_97_1
PubMedID: 30790623

Title : Evaluating Mice lacking Serum Carboxylesterase as a Behavioral Model for Nerve Agent Intoxication - Dunn_2018_Toxicol.Mech.Methods__1
Author(s) : Dunn EN , Ferrara-Bowens TM , Chachich ME , Honnold CL , Rothwell CC , Hoard-Fruchey HM , Lesyna CA , Johnson EA , Cerasoli DM , McDonough JH , Cadieux CL
Ref : Toxicol Mech Methods , :1 , 2018
Abstract :
PubMedSearch : Dunn_2018_Toxicol.Mech.Methods__1
PubMedID: 29768075
Gene_locus related to this paper: mouse-Ces1g

Title : Behavioral, Pharmacokinetic, and Cardiovascular Evaluation of Candidate Oximes in African Green Monkeys - Moffett_2018_Int.J.Toxicol__1091581818779362
Author(s) : Moffett MC , McDonough JH , McMonagle JD , Myers TM
Ref : Int J Toxicol , :1091581818779362 , 2018
Abstract :
PubMedSearch : Moffett_2018_Int.J.Toxicol__1091581818779362
PubMedID: 29879849

Title : Assessment of mouse strain differences in baseline esterase activities and toxic response to sarin - Matson_2018_Toxicology_410_10
Author(s) : Matson LM , Lee-Stubbs RB , Cadieux CL , Koenig JA , Ardinger CE , Chandler J , Johnson EA , Hoard-Fruchey HM , Shih TA , Cerasoli DM , McDonough JH
Ref : Toxicology , 410 :10 , 2018
Abstract :
PubMedSearch : Matson_2018_Toxicology_410_10
PubMedID: 30172647

Title : The role of genetic background in susceptibility to chemical warfare nerve agents across rodent and non-human primate models - Matson_2017_Toxicology_393_51
Author(s) : Matson LM , McCarren HS , Cadieux CL , Cerasoli DM , McDonough JH
Ref : Toxicology , 393 :51 , 2017
Abstract :
PubMedSearch : Matson_2017_Toxicology_393_51
PubMedID: 29113833

Title : The synthetic neuroactive steroid SGE-516 reduces status epilepticus and neuronal cell death in a rat model of soman intoxication - Althaus_2017_Epilepsy.Behav_68_22
Author(s) : Althaus AL , McCarren HS , Alqazzaz A , Jackson C , McDonough JH , Smith CD , Hoffman E , Hammond RS , Robichaud AJ , Doherty JJ
Ref : Epilepsy Behav , 68 :22 , 2017
Abstract :
PubMedSearch : Althaus_2017_Epilepsy.Behav_68_22
PubMedID: 28109985

Title : (-)-phenserine attenuates soman-induced neuropathology - Chen_2014_PLoS.One_9_e99818
Author(s) : Chen J , Pan H , Chen C , Wu W , Iskandar K , He J , Piermartiri T , Jacobowitz DM , Yu QS , McDonough JH , Greig NH , Marini AM
Ref : PLoS ONE , 9 :e99818 , 2014
Abstract :
PubMedSearch : Chen_2014_PLoS.One_9_e99818
PubMedID: 24955574

Title : The oxime pro-2-PAM provides minimal protection against the CNS effects of the nerve agents sarin, cyclosarin, and VX in guinea pigs - Shih_2011_Toxicol.Mech.Methods_21_53
Author(s) : Shih TM , Guarisco JA , Myers TM , Kan RK , McDonough JH
Ref : Toxicol Mech Methods , 21 :53 , 2011
Abstract :
PubMedSearch : Shih_2011_Toxicol.Mech.Methods_21_53
PubMedID: 21117832

Title : In vivo microdialysis and electroencephalographic activity in freely moving guinea pigs exposed to organophosphorus nerve agents sarin and VX: analysis of acetylcholine and glutamate - O'Donnell_2011_Arch.Toxicol_85_1607
Author(s) : O'Donnell JC , McDonough JH , Shih TM
Ref : Archives of Toxicology , 85 :1607 , 2011
Abstract :
PubMedSearch : O'Donnell_2011_Arch.Toxicol_85_1607
PubMedID: 21695469

Title : Protection against sarin-induced seizures in rats by direct brain microinjection of scopolamine, midazolam or MK-801 - Skovira_2010_J.Mol.Neurosci_40_56
Author(s) : Skovira JW , McDonough JH , Shih TM
Ref : Journal of Molecular Neuroscience , 40 :56 , 2010
Abstract :
PubMedSearch : Skovira_2010_J.Mol.Neurosci_40_56
PubMedID: 19690985

Title : In vivo reactivation by oximes of inhibited blood, brain and peripheral tissue cholinesterase activity following exposure to nerve agents in guinea pigs - Shih_2010_Chem.Biol.Interact_187_207
Author(s) : Shih TM , Skovira JW , O'Donnell JC , McDonough JH
Ref : Chemico-Biological Interactions , 187 :207 , 2010
Abstract :
PubMedSearch : Shih_2010_Chem.Biol.Interact_187_207
PubMedID: 20223229

Title : Comparison of extracellular striatal acetylcholine and brain seizure activity following acute exposure to the nerve agents cyclosarin and tabun in freely moving guinea pigs - O'Donnell_2010_Toxicol.Mech.Methods_20_600
Author(s) : O'Donnell JC , Acon-Chen C , McDonough JH , Shih TM
Ref : Toxicol Mech Methods , 20 :600 , 2010
Abstract :
PubMedSearch : O'Donnell_2010_Toxicol.Mech.Methods_20_600
PubMedID: 20919801

Title : Changes in extracellular striatal acetylcholine and brain seizure activity following acute exposure to nerve agents in freely moving guinea pigs - O'Donnell_2010_Toxicol.Mech.Methods_20_143
Author(s) : O'Donnell JC , McDonough JH , Shih TM
Ref : Toxicol Mech Methods , 20 :143 , 2010
Abstract :
PubMedSearch : O'Donnell_2010_Toxicol.Mech.Methods_20_143
PubMedID: 20163292

Title : Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication - Shih_2010_J.Mol.Neurosci_40_63
Author(s) : Shih TM , Skovira JW , O'Donnell JC , McDonough JH
Ref : Journal of Molecular Neuroscience , 40 :63 , 2010
Abstract :
PubMedSearch : Shih_2010_J.Mol.Neurosci_40_63
PubMedID: 19680820

Title : Reactivation of brain acetylcholinesterase by monoisonitrosoacetone increases the therapeutic efficacy against nerve agents in guinea pigs - Skovira_2010_Chem.Biol.Interact_187_318
Author(s) : Skovira JW , O'Donnell JC , Koplovitz I , Kan RK , McDonough JH , Shih TM
Ref : Chemico-Biological Interactions , 187 :318 , 2010
Abstract :
PubMedSearch : Skovira_2010_Chem.Biol.Interact_187_318
PubMedID: 20230808

Title : Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs - Shih_2009_Arch.Toxicol_83_1083
Author(s) : Shih TM , Skovira JW , McDonough JH
Ref : Archives of Toxicology , 83 :1083 , 2009
Abstract :
PubMedSearch : Shih_2009_Arch.Toxicol_83_1083
PubMedID: 19763542

Title : In vivo oxime administration does not influence Ellman acetylcholinesterase assay results - Guarisco_2009_Toxicol.Mech.Methods_19_379
Author(s) : Guarisco JA , O'Donnell JC , Skovira JW , McDonough JH , Shih TM
Ref : Toxicol Mech Methods , 19 :379 , 2009
Abstract :
PubMedSearch : Guarisco_2009_Toxicol.Mech.Methods_19_379
PubMedID: 19778238

Title : Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose - Shih_2009_Toxicol.Mech.Methods_19_386
Author(s) : Shih TM , Skovira JW , O'Donnell JC , McDonough JH
Ref : Toxicol Mech Methods , 19 :386 , 2009
Abstract :
PubMedSearch : Shih_2009_Toxicol.Mech.Methods_19_386
PubMedID: 19778239

Title : Kinetics of sarin (GB) following a single sublethal inhalation exposure in the guinea pig - Whalley_2007_Inhal.Toxicol_19_667
Author(s) : Whalley CE , McGuire JM , Miller DB , Jakubowski EM , Mioduszewski RJ , Thomson SA , Lumley LA , McDonough JH , Shih TM
Ref : Inhal Toxicol , 19 :667 , 2007
Abstract :
PubMedSearch : Whalley_2007_Inhal.Toxicol_19_667
PubMedID: 17510839

Title : The effects of repeated low-dose sarin exposure - Shih_2006_Toxicol.Appl.Pharmacol_215_119
Author(s) : Shih TM , Hulet SW , McDonough JH
Ref : Toxicol Appl Pharmacol , 215 :119 , 2006
Abstract :
PubMedSearch : Shih_2006_Toxicol.Appl.Pharmacol_215_119
PubMedID: 16556454

Title : In vivo cholinesterase inhibitory specificity of organophosphorus nerve agents - Shih_2005_Chem.Biol.Interact_157-158_293
Author(s) : Shih TM , Kan RK , McDonough JH
Ref : Chemico-Biological Interactions , 157-158 :293 , 2005
Abstract :
PubMedSearch : Shih_2005_Chem.Biol.Interact_157-158_293
PubMedID: 16256093

Title : Pharmacokinetic studies of intramuscular midazolam in guinea pigs challenged with soman - Capacio_2004_Drug.Chem.Toxicol_27_95
Author(s) : Capacio BR , Byers CE , Merk KA , Smith JR , McDonough JH
Ref : Drug & Chemical Toxicology , 27 :95 , 2004
Abstract :
PubMedSearch : Capacio_2004_Drug.Chem.Toxicol_27_95
PubMedID: 15198070

Title : The dose-response effects of repeated subacute sarin exposure on guinea pigs - Hulet_2002_Pharmacol.Biochem.Behav_72_835
Author(s) : Hulet SW , McDonough JH , Shih TM
Ref : Pharmacol Biochem Behav , 72 :835 , 2002
Abstract :
PubMedSearch : Hulet_2002_Pharmacol.Biochem.Behav_72_835
PubMedID: 12062573

Title : Intramuscular diazepam pharmacokinetics in soman-exposed guinea pigs - Capacio_2001_J.Appl.Toxicol_21 Suppl 1_S67
Author(s) : Capacio BR , Whalley CE , Byers CE , McDonough JH
Ref : J Appl Toxicol , 21 Suppl 1 :S67 , 2001
Abstract :
PubMedSearch : Capacio_2001_J.Appl.Toxicol_21 Suppl 1_S67
PubMedID: 11920923

Title : Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication - Shih_2000_Arch.Toxicol_74_165
Author(s) : Shih TM , McDonough JH
Ref : Archives of Toxicology , 74 :165 , 2000
Abstract :
PubMedSearch : Shih_2000_Arch.Toxicol_74_165
PubMedID: 10877003