| Title : Combination therapy for the treatment of alzheimer's disease: recent progress and future prospects - Shirbhate_2022_Curr.Top.Med.Chem__ |
| Author(s) : Shirbhate E , Patel VK , Tiwari P , Kore R , Veerasamy R , Mishra A , Rajak H |
| Ref : Curr Top Med Chem , : , 2022 |
| Abstract : |
| PubMedSearch : Shirbhate_2022_Curr.Top.Med.Chem__ |
| PubMedID: 36082857 |
| Title : Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor - Measom_2017_ACS.Med.Chem.Lett_8_43 |
| Author(s) : Measom ND , Down KD , Hirst DJ , Jamieson C , Manas ES , Patel VK , Somers DO |
| Ref : ACS Med Chem Lett , 8 :43 , 2017 |
| Abstract : |
| PubMedSearch : Measom_2017_ACS.Med.Chem.Lett_8_43 |
| PubMedID: 28105273 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening - Woolford_2016_J.Med.Chem_59_5356 |
| Author(s) : Woolford AJ , Pero JE , Aravapalli S , Berdini V , Coyle JE , Day PJ , Dodson AM , Grondin P , Holding FP , Lee LY , Li P , Manas ES , Marino J, Jr. , Martin AC , McCleland BW , McMenamin RL , Murray CW , Neipp CE , Page LW , Patel VK , Potvain F , Rich S , Rivero RA , Smith K , Somers DO , Trottet L , Velagaleti R , Williams G , Xie R |
| Ref : Journal of Medicinal Chemistry , 59 :5356 , 2016 |
| Abstract : |
| PubMedSearch : Woolford_2016_J.Med.Chem_59_5356 |
| PubMedID: 27167608 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) - Woolford_2016_J.Med.Chem_59_10738 |
| Author(s) : Woolford AJ , Day PJ , Beneton V , Berdini V , Coyle JE , Dudit Y , Grondin P , Huet P , Lee LY , Manas ES , McMenamin RL , Murray CW , Page LW , Patel VK , Potvain F , Rich SJ , Sang Y , Somers DO , Trottet L , Wan Z , Zhang X |
| Ref : Journal of Medicinal Chemistry , 59 :10738 , 2016 |
| Abstract : |
| PubMedSearch : Woolford_2016_J.Med.Chem_59_10738 |
| PubMedID: 27933945 |
| Gene_locus related to this paper: human-PLA2G7 |