| Title : Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders - Harrison_2023_J.Med.Chem_66_14897 |
| Author(s) : Harrison D , Billinton A , Bock MG , Doedens JR , Gabel CA , Holloway MK , Porter RA , Reader V , Scanlon J , Schooley K , Watt AP |
| Ref : Journal of Medicinal Chemistry , 66 :14897 , 2023 |
| Abstract : |
| PubMedSearch : Harrison_2023_J.Med.Chem_66_14897 |
| PubMedID: 37874905 |
| Title : Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders - Harrison_2023_J.Med.Chem_66_14897 |
| Author(s) : Harrison D , Billinton A , Bock MG , Doedens JR , Gabel CA , Holloway MK , Porter RA , Reader V , Scanlon J , Schooley K , Watt AP |
| Ref : Journal of Medicinal Chemistry , 66 :14897 , 2023 |
| Abstract : |
| PubMedSearch : Harrison_2023_J.Med.Chem_66_14897 |
| PubMedID: 37874905 |
| Title : Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders - Harrison_2023_J.Med.Chem_66_14897 |
| Author(s) : Harrison D , Billinton A , Bock MG , Doedens JR , Gabel CA , Holloway MK , Porter RA , Reader V , Scanlon J , Schooley K , Watt AP |
| Ref : Journal of Medicinal Chemistry , 66 :14897 , 2023 |
| Abstract : |
| PubMedSearch : Harrison_2023_J.Med.Chem_66_14897 |
| PubMedID: 37874905 |
| Title : Discovery of a Series of Ester-substituted NLRP3 Inflammasome Inhibitors - Harrison_2020_Bioorg.Med.Chem.Lett__127560 |
| Author(s) : Harrison D , Boutard N , Brzozka K , Bugaj M , Chmielewski S , Cierpich A , Doedens JR , CH RYF , Gabel CA , Galezowski M , Kowalczyk P , Levenets O , Mroczkowska M , Palica K , Porter RA , Schultz D , Sowinska M , Topolnicki G , Urbanski P , Woyciechowski J , Watt AP |
| Ref : Bioorganic & Medicinal Chemistry Lett , :127560 , 2020 |
| Abstract : |
| PubMedSearch : Harrison_2020_Bioorg.Med.Chem.Lett__127560 |
| PubMedID: 32956781 |
| Title : Discovery of a Series of Ester-substituted NLRP3 Inflammasome Inhibitors - Harrison_2020_Bioorg.Med.Chem.Lett__127560 |
| Author(s) : Harrison D , Boutard N , Brzozka K , Bugaj M , Chmielewski S , Cierpich A , Doedens JR , CH RYF , Gabel CA , Galezowski M , Kowalczyk P , Levenets O , Mroczkowska M , Palica K , Porter RA , Schultz D , Sowinska M , Topolnicki G , Urbanski P , Woyciechowski J , Watt AP |
| Ref : Bioorganic & Medicinal Chemistry Lett , :127560 , 2020 |
| Abstract : |
| PubMedSearch : Harrison_2020_Bioorg.Med.Chem.Lett__127560 |
| PubMedID: 32956781 |
| Title : Discovery of a Series of Ester-substituted NLRP3 Inflammasome Inhibitors - Harrison_2020_Bioorg.Med.Chem.Lett__127560 |
| Author(s) : Harrison D , Boutard N , Brzozka K , Bugaj M , Chmielewski S , Cierpich A , Doedens JR , CH RYF , Gabel CA , Galezowski M , Kowalczyk P , Levenets O , Mroczkowska M , Palica K , Porter RA , Schultz D , Sowinska M , Topolnicki G , Urbanski P , Woyciechowski J , Watt AP |
| Ref : Bioorganic & Medicinal Chemistry Lett , :127560 , 2020 |
| Abstract : |
| PubMedSearch : Harrison_2020_Bioorg.Med.Chem.Lett__127560 |
| PubMedID: 32956781 |
| Title : M3 muscarinic acetylcholine receptors regulate cytoplasmic myosin by a process involving RhoA and requiring conventional protein kinase C isoforms - Strassheim_1999_J.Biol.Chem_274_18675 |
| Author(s) : Strassheim D , May LG , Varker KA , Puhl HL , Phelps SH , Porter RA , Aronstam RS , Noti JD , Williams CL |
| Ref : Journal of Biological Chemistry , 274 :18675 , 1999 |
| Abstract : |
| PubMedSearch : Strassheim_1999_J.Biol.Chem_274_18675 |
| PubMedID: 10373480 |
| Title : M3 muscarinic acetylcholine receptors regulate cytoplasmic myosin by a process involving RhoA and requiring conventional protein kinase C isoforms - Strassheim_1999_J.Biol.Chem_274_18675 |
| Author(s) : Strassheim D , May LG , Varker KA , Puhl HL , Phelps SH , Porter RA , Aronstam RS , Noti JD , Williams CL |
| Ref : Journal of Biological Chemistry , 274 :18675 , 1999 |
| Abstract : |
| PubMedSearch : Strassheim_1999_J.Biol.Chem_274_18675 |
| PubMedID: 10373480 |
| Title : M3 muscarinic acetylcholine receptors regulate cytoplasmic myosin by a process involving RhoA and requiring conventional protein kinase C isoforms - Strassheim_1999_J.Biol.Chem_274_18675 |
| Author(s) : Strassheim D , May LG , Varker KA , Puhl HL , Phelps SH , Porter RA , Aronstam RS , Noti JD , Williams CL |
| Ref : Journal of Biological Chemistry , 274 :18675 , 1999 |
| Abstract : |
| PubMedSearch : Strassheim_1999_J.Biol.Chem_274_18675 |
| PubMedID: 10373480 |