Title : Phospho-NSAIDs Have Enhanced Efficacy in Mice Lacking Plasma Carboxylesterase: Implications for their Clinical Pharmacology - Wong_2015_Pharm.Res_32_1663 |
Author(s) : Wong CC , Cheng KW , Papayannis I , Mattheolabakis G , Huang L , Xie G , Ouyang N , Rigas B |
Ref : Pharm Res , 32 :1663 , 2015 |
Abstract : |
PubMedSearch : Wong_2015_Pharm.Res_32_1663 |
PubMedID: 25392229 |
Title : Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen - Mattheolabakis_2014_J.Pharmacol.Exp.Ther_351_61 |
Author(s) : Mattheolabakis G , Wong CC , Sun Y , Amella CA , Richards R , Constantinides PP , Rigas B |
Ref : Journal of Pharmacology & Experimental Therapeutics , 351 :61 , 2014 |
Abstract : |
PubMedSearch : Mattheolabakis_2014_J.Pharmacol.Exp.Ther_351_61 |
PubMedID: 25047517 |
Title : Comparative in vitro metabolism of phospho-tyrosol-indomethacin by mice, rats and humans - Xie_2013_Biochem.Pharmacol_85_1195 |
Author(s) : Xie G , Zhou D , Cheng KW , Wong CC , Rigas B |
Ref : Biochemical Pharmacology , 85 :1195 , 2013 |
Abstract : |
PubMedSearch : Xie_2013_Biochem.Pharmacol_85_1195 |
PubMedID: 23399640 |
Title : Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity - Wong_2012_J.Pharmacol.Exp.Ther_340_422 |
Author(s) : Wong CC , Cheng KW , Xie G , Zhou D , Zhu CH , Constantinides PP , Rigas B |
Ref : Journal of Pharmacology & Experimental Therapeutics , 340 :422 , 2012 |
Abstract : |
PubMedSearch : Wong_2012_J.Pharmacol.Exp.Ther_340_422 |
PubMedID: 22085648 |