| Title : LEGACY: Phase 2a Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of the Anti-EL (Endothelial Lipase) Antibody MEDI5884 in Patients With Stable Coronary Artery Disease - Ruff_2021_Arterioscler.Thromb.Vasc.Biol__ATVBAHA120315757 |
| Author(s) : Ruff CT , Koren MJ , Grimsby J , Rosenbaum AI , Tu X , Karathanasis SK , Falloon J , Hsia J , Guan Y , Conway J , Tsai LF , Hummer BT , Hirshberg B , Kuder J , Murphy SA , George RT , Sabatine MS |
| Ref : Arterioscler Thromb Vasc Biol , :ATVBAHA120315757 , 2021 |
| Abstract : |
| PubMedSearch : Ruff_2021_Arterioscler.Thromb.Vasc.Biol__ATVBAHA120315757 |
| PubMedID: 34706556 |
| Title : Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics - Rosenbaum_2010_J.Med.Chem_53_5281 |
| Author(s) : Rosenbaum AI , Cosner CC , Mariani CJ , Maxfield FR , Wiest O , Helquist P |
| Ref : Journal of Medicinal Chemistry , 53 :5281 , 2010 |
| Abstract : |
| PubMedSearch : Rosenbaum_2010_J.Med.Chem_53_5281 |
| PubMedID: 20557099 |
| Title : Chemical screen to reduce sterol accumulation in Niemann-Pick C disease cells identifies novel lysosomal acid lipase inhibitors - Rosenbaum_2009_Biochim.Biophys.Acta_1791_1155 |
| Author(s) : Rosenbaum AI , Rujoi M , Huang AY , Du H , Grabowski GA , Maxfield FR |
| Ref : Biochimica & Biophysica Acta , 1791 :1155 , 2009 |
| Abstract : |
| PubMedSearch : Rosenbaum_2009_Biochim.Biophys.Acta_1791_1155 |
| PubMedID: 19699313 |