Full name : Saunders John
First name : John
Mail : Medicinal Chemistry II, Glaxo Group Research, Greenford, Middlesex
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Country : United Kingdom
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| Title : Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape - Vongsouthi_2025_Sci.Adv_11_eads8318 |
| Author(s) : Vongsouthi V , Georgelin R , Matthews DS , Saunders J , Lee BM , Ton J , Damry AM , Frkic RL , Spence MA , Jackson CJ |
| Ref : Sci Adv , 11 :eads8318 , 2025 |
| Abstract : |
| PubMedSearch : Vongsouthi_2025_Sci.Adv_11_eads8318 |
| PubMedID: 40367179 |
| Gene_locus related to this paper: 9zzz-AncPETase |
| Title : Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape - Vongsouthi_2024_bioRxiv__ |
| Author(s) : Vongsouthi V , Georgelin R , Matthews D , Saunders J , Lee BM , Ton J , Damry AM , Frkic RL , Spence MA , Jackson CJ |
| Ref : bioRxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Vongsouthi_2024_bioRxiv__ |
| PubMedID: |
| Gene_locus related to this paper: 9zzz-AncPETase |
| Title : Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density - Cao_2012_Behav.Neurosci_126_332 |
| Author(s) : Cao YA , Featherstone RE , Gandal MJ , Liang Y , Jutzeler C , Saunders J , Tatard-Leitman V , Chen J , Weinberger DR , Lerman C , Siegel SJ |
| Ref : Behavioral Neuroscience , 126 :332 , 2012 |
| Abstract : |
| PubMedSearch : Cao_2012_Behav.Neurosci_126_332 |
| PubMedID: 22309446 |
| Title : Ligand binding model for G-protein-linked receptors: an update - Saunders_1993_Drug.Des.Discov_9_213 |
| Author(s) : Saunders J |
| Ref : Drug Des Discov , 9 :213 , 1993 |
| Abstract : |
| PubMedSearch : Saunders_1993_Drug.Des.Discov_9_213 |
| PubMedID: 8104519 |
| Title : Synthesis and muscarinic activity of quinuclidinyl- and (1-azanorbornyl)pyrazine derivatives - Street_1992_J.Med.Chem_35_295 |
| Author(s) : Street LJ , Baker R , Book T , Reeve AJ , Saunders J , Willson T , Marwood RS , Patel S , Freedman SB |
| Ref : Journal of Medicinal Chemistry , 35 :295 , 1992 |
| Abstract : |
| PubMedSearch : Street_1992_J.Med.Chem_35_295 |
| PubMedID: 1732546 |
| Title : L-687,306: a functionally selective and potent muscarinic M1 receptor agonist - Freedman_1992_Eur.J.Pharmacol_215_135 |
| Author(s) : Freedman SB , Patel S , Harley EA , Iversen LL , Baker R , Showell GA , Saunders J , McKnight A , Newberry N , Scholey K , Hargreaves R |
| Ref : European Journal of Pharmacology , 215 :135 , 1992 |
| Abstract : |
| PubMedSearch : Freedman_1992_Eur.J.Pharmacol_215_135 |
| PubMedID: 1516645 |
| Title : Tetrahydropyridyloxadiazoles: semirigid muscarinic ligands - Showell_1991_J.Med.Chem_34_1086 |
| Author(s) : Showell GA , Gibbons TL , Kneen CO , MacLeod AM , Merchant K , Saunders J , Freedman SB , Patel S , Baker R |
| Ref : Journal of Medicinal Chemistry , 34 :1086 , 1991 |
| Abstract : |
| PubMedSearch : Showell_1991_J.Med.Chem_34_1086 |
| PubMedID: 2002451 |
| Title : Synthesis and muscarinic activities of 1,2,4-thiadiazoles - MacLeod_1990_J.Med.Chem_33_2052 |
| Author(s) : MacLeod AM , Baker R , Freedman SB , Patel S , Merchant KJ , Roe M , Saunders J |
| Ref : Journal of Medicinal Chemistry , 33 :2052 , 1990 |
| Abstract : |
| PubMedSearch : MacLeod_1990_J.Med.Chem_33_2052 |
| PubMedID: 2362286 |
| Title : Novel quinuclidine-based ligands for the muscarinic cholinergic receptor - Saunders_1990_J.Med.Chem_33_1128 |
| Author(s) : Saunders J , Cassidy M , Freedman SB , Harley EA , Iversen LL , Kneen C , MacLeod AM , Merchant KJ , Snow RJ , Baker R |
| Ref : Journal of Medicinal Chemistry , 33 :1128 , 1990 |
| Abstract : |
| PubMedSearch : Saunders_1990_J.Med.Chem_33_1128 |
| PubMedID: 2319559 |
| Title : Monoamine neurotransmitter receptors: ligand-receptor models - Saunders_1990_Biochem.Soc.Symp_57_81 |
| Author(s) : Saunders J , Findlay JB |
| Ref : Biochemical Society Symposium , 57 :81 , 1990 |
| Abstract : |
| PubMedSearch : Saunders_1990_Biochem.Soc.Symp_57_81 |
| PubMedID: 1983086 |
| Title : Synthesis and biological activity of 1,2,4-oxadiazole derivatives: highly potent and efficacious agonists for cortical muscarinic receptors - Street_1990_J.Med.Chem_33_2690 |
| Author(s) : Street LJ , Baker R , Book T , Kneen CO , MacLeod AM , Merchant KJ , Showell GA , Saunders J , Herbert RH , Freedman SB , Harley EA |
| Ref : Journal of Medicinal Chemistry , 33 :2690 , 1990 |
| Abstract : |
| PubMedSearch : Street_1990_J.Med.Chem_33_2690 |
| PubMedID: 2213823 |
| Title : Poster: Tetrahydropyridyl-oxadiazoles: ligands used to map the muscarinic receptor - |
| Author(s) : Showell GA , Merchant K , Baker R , Freedman SB , Saunders J |
| Ref : Trends in Pharmacological Sciences , Suppl :112 , 1989 |
| PubMedID: |
| Title : Poster: 5-Hydroxyquinuclidine oxadiazoles: stereochemical probes for the agonist binding state of the muscarinic receptor - |
| Author(s) : Snow RJ , Freedman SB , Baker R , Saunders J |
| Ref : Trends in Pharmacological Sciences , Suppl :112 , 1989 |
| PubMedID: |
| Title : An analysis of the periodicity of conserved residues in sequence alignments of G-protein coupled receptors. Implications for the three-dimensional structure - Donnelly_1989_FEBS.Lett_251_109 |
| Author(s) : Donnelly D , Johnson MS , Blundell TL , Saunders J |
| Ref : FEBS Letters , 251 :109 , 1989 |
| Abstract : |
| PubMedSearch : Donnelly_1989_FEBS.Lett_251_109 |
| PubMedID: 2546817 |
| Title : The design of full agonists for the cortical muscarinic receptor - Saunders_1989_Trends.Pharmacol.Sci_Suppl_70 |
| Author(s) : Saunders J , Freedman SB |
| Ref : Trends in Pharmacological Sciences , Suppl :70 , 1989 |
| Abstract : |
| PubMedSearch : Saunders_1989_Trends.Pharmacol.Sci_Suppl_70 |
| PubMedID: 2694527 |
| Title : 2-Methyl-1,3-dioxaazaspiro[4.5]decanes as novel muscarinic cholinergic agonists - Saunders_1988_J.Med.Chem_31_486 |
| Author(s) : Saunders J , Showell GA , Snow RJ , Baker R , Harley EA , Freedman SB |
| Ref : Journal of Medicinal Chemistry , 31 :486 , 1988 |
| Abstract : |
| PubMedSearch : Saunders_1988_J.Med.Chem_31_486 |
| PubMedID: 3339620 |
| Title : Synthesis and characterization of all four isomers of the muscarinic agonist 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane] - Saunders_1987_J.Med.Chem_30_969 |
| Author(s) : Saunders J , Showell GA , Baker R , Freedman SB , Hill D , McKnight A , Newberry N , Salamone JD , Hirshfield J , Springer JP |
| Ref : Journal of Medicinal Chemistry , 30 :969 , 1987 |
| Abstract : |
| PubMedSearch : Saunders_1987_J.Med.Chem_30_969 |
| PubMedID: 3585909 |
| Title : Local anesthetic- and halothane-induced alterations of the stimulation-induced release of 3H-dopamine from rat striatal slices - |
| Author(s) : Westfall TC , DiFazio CA , Saunders J |
| Ref : Anesthesiology , 48 :118 , 1978 |
| PubMedID: 655443 |
| Title : Absence of nicotinic receptors mediating the release of norepinephrine from adrenergic neurons in the rat heart - |
| Author(s) : Westfall TC , Saunders J |
| Ref : Proc Soc Exp Biol Med , 156 :476 , 1977 |
| PubMedID: 594078 |
| Title : Hardrurus arizonensis venom: a new source of acetylcholinesterase - |
| Author(s) : Saunders J , Johnson BD |
| Ref : American Journal of Tropical Medicine & Hygiene , 19 :345 , 1970 |
| PubMedID: 5443083 |