| Title : DFT-Based Elucidation and Evaluation of Selenium-Modified Tacrine Derivatives: Theoretical and Physicochemical Insights for Alzheimer's Disease Therapy - Morais_2025_Molecules_30_ |
| Author(s) : Morais RB , Sacramento MD , Scimmi C , Lourenco DA , Kremer FS , Savegnago L , Alves D |
| Ref : Molecules , 30 : , 2025 |
| Abstract : |
| PubMedSearch : Morais_2025_Molecules_30_ |
| PubMedID: 40572521 |
| Title : Mechanisms involved in the antidepressant-like action of orally administered 5-((4-methoxyphenyl)thio)benzo[c][1,2,5]thiadiazole (MTDZ) in male and female mice - da Costa Rodrigues_2024_Psychopharmacology.(Berl)__ |
| Author(s) : da Costa Rodrigues K , da Conceicao Oliveira M , Dos Santos BF , de Campos Domingues NL , Fronza MG , Savegnago L , Wilhelm EA , Luchese C |
| Ref : Psychopharmacology (Berl) , : , 2024 |
| Abstract : |
| PubMedSearch : da Costa Rodrigues_2024_Psychopharmacology.(Berl)__ |
| PubMedID: 39008059 |
| Title : The Neurobiology and Therapeutic Potential of Multi-Targeting beta-secretase, Glycogen Synthase Kinase 3beta and Acetylcholinesterase in Alzheimer's Disease - Fronza_2023_Ageing.Res.Rev__102033 |
| Author(s) : Fronza MG , Alves D , Pratico D , Savegnago L |
| Ref : Ageing Res Rev , :102033 , 2023 |
| Abstract : |
| PubMedSearch : Fronza_2023_Ageing.Res.Rev__102033 |
| PubMedID: 37595640 |
| Title : QTC-4-MeOBnE Ameliorated Depressive-Like Behavior and Memory Impairment in 3xTg Mice - Fronza_2022_Mol.Neurobiol__ |
| Author(s) : Fronza MG , Sacramento M , Alves D , Pratico D , Savegnago L |
| Ref : Molecular Neurobiology , : , 2022 |
| Abstract : |
| PubMedSearch : Fronza_2022_Mol.Neurobiol__ |
| PubMedID: 36567360 |
| Title : 1-(7-Chloroquinolin-4-yl)-N-(4-Methoxybenzyl)-5-Methyl-1H-1,2, 3-Triazole-4- carboxamide Reduces Abeta Formation and Tau Phosphorylation in Cellular Models of Alzheimer's Disease - Fronza_2022_Neurochem.Res__ |
| Author(s) : Fronza MG , Sacramento M , Alves D , Pratico D , Savegnago L |
| Ref : Neurochem Res , : , 2022 |
| Abstract : |
| PubMedSearch : Fronza_2022_Neurochem.Res__ |
| PubMedID: 35165799 |
| Title : Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na(+)\/K(+)-ATPase in an Alzheimer's disease model - Pinz_2021_Metab.Brain.Dis__ |
| Author(s) : Pinz MP , Vogt AG , da Costa Rodrigues K , Dos Reis AS , Duarte LFB , Fronza MG , Domingues WB , Blodorn EB , Alves D , Campos VF , Savegnago L , Wilhelm EA , Luchese C |
| Ref : Metabolic Brain Disease , : , 2021 |
| Abstract : |
| PubMedSearch : Pinz_2021_Metab.Brain.Dis__ |
| PubMedID: 33651275 |
| Title : Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: the role of blood-brain barrier permeability, NF-kB signaling, and microglial activation - Fronza_2021_Brain.Behav.Immun__ |
| Author(s) : Fronza MG , Baldinotti R , Fetter J , Goncalves Rosa S , Sacramento M , Wayne Nogueira C , Alves D , Pratic D , Savegnago L |
| Ref : Brain Behavior & Immunity , : , 2021 |
| Abstract : |
| PubMedSearch : Fronza_2021_Brain.Behav.Immun__ |
| PubMedID: 34624485 |
| Title : Protective effects of octylseleno-xylofuranoside in a streptozotocin-induced mouse model of Alzheimer's disease - Baldinotti_2021_Eur.J.Pharmacol__174499 |
| Author(s) : Baldinotti R , Fronza MG , Silva L , Bender CB , Ludtke DS , Seixas FK , Collares T , Alves D , Savegnago L |
| Ref : European Journal of Pharmacology , :174499 , 2021 |
| Abstract : |
| PubMedSearch : Baldinotti_2021_Eur.J.Pharmacol__174499 |
| PubMedID: 34508753 |
| Title : Effect of QTC-4-MeOBnE Treatment on Memory, Neurodegeneration, and Neurogenesis in a Streptozotocin-Induced Mouse Model of Alzheimer's Disease - Fronza_2021_ACS.Chem.Neurosci_12_109 |
| Author(s) : Fronza MG , Baldinotti R , Sacramento M , Gutierres J , Carvalho FB , Fernandes MDC , Sousa FSS , Seixas FK , Collares T , Alves D , Pratico D , Savegnago L |
| Ref : ACS Chem Neurosci , 12 :109 , 2021 |
| Abstract : |
| PubMedSearch : Fronza_2021_ACS.Chem.Neurosci_12_109 |
| PubMedID: 33315382 |
| Title : A new arylsulfanyl-benzo-2,1,3-thiadiazoles derivative produces an anti-amnesic effect in mice by modulating acetylcholinesterase activity - da Costa Rodrigues_2021_Chem.Biol.Interact_351_109736 |
| Author(s) : da Costa Rodrigues K , Leivas de Oliveira R , da Silva Chaves J , Esteves da Rocha VM , Fuzinato Dos Santos B , Fronza MG , Luis de Campos Domingues N , Savegnago L , Wilhelm EA , Luchese C |
| Ref : Chemico-Biological Interactions , 351 :109736 , 2021 |
| Abstract : |
| PubMedSearch : da Costa Rodrigues_2021_Chem.Biol.Interact_351_109736 |
| PubMedID: 34740600 |
| Title : Synthesis, molecular docking and preliminary evaluation of 2-(1,2,3-triazoyl)-benzaldehydes as multifunctional agents for the treatment of Alzheimer's disease - Costa_2020_ChemMedChem__ |
| Author(s) : Costa GP , Baldinotti R , Fronza MG , Nascimento JE , Dias I , Sonego MS , Seixas FK , Collares T , Perin G , Jacob RG , Savegnago L , Alves D |
| Ref : ChemMedChem , : , 2020 |
| Abstract : |
| PubMedSearch : Costa_2020_ChemMedChem__ |
| PubMedID: 32012463 |
| Title : QTC-4-MeOBnE rescues scopolamine-induced memory deficits in mice by targeting oxidative stress, neuronal plasticity and apoptosis - Fronza_2020_ACS.Chem.Neurosci_11_1259 |
| Author(s) : Fronza MG , Baldinotti R , Fetter J , Sacramento M , Sousa FSS , Seixas FK , Collares T , Alves D , Pratico D , Savegnago L |
| Ref : ACS Chem Neurosci , 11 :1259 , 2020 |
| Abstract : |
| PubMedSearch : Fronza_2020_ACS.Chem.Neurosci_11_1259 |
| PubMedID: 32227985 |
| Title : Repeated administration of a selenium-containing indolyl compound attenuates behavioural alterations by streptozotocin through modulation of oxidative stress in mice - Bampi_2019_Pharmacol.Biochem.Behav_183_46 |
| Author(s) : Bampi SR , Casaril AM , Sabedra Sousa FS , Pesarico AP , Vieira B , Lenardao EJ , Savegnago L |
| Ref : Pharmacol Biochem Behav , 183 :46 , 2019 |
| Abstract : |
| PubMedSearch : Bampi_2019_Pharmacol.Biochem.Behav_183_46 |
| PubMedID: 31207269 |
| Title : Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer's disease - Fronza_2019_Sci.Rep_9_7276 |
| Author(s) : Fronza MG , Baldinotti R , Martins MC , Goldani B , Dalberto BT , Kremer FS , Begnini K , Pinto LDS , Lenardao EJ , Seixas FK , Collares T , Alves D , Savegnago L |
| Ref : Sci Rep , 9 :7276 , 2019 |
| Abstract : |
| PubMedSearch : Fronza_2019_Sci.Rep_9_7276 |
| PubMedID: 31086208 |
| Title : Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures - Wilhelm_2009_Brain.Res.Bull_79_281 |
| Author(s) : Wilhelm EA , Jesse CR , Bortolatto CF , Nogueira CW , Savegnago L |
| Ref : Brain Research Bulletin , 79 :281 , 2009 |
| Abstract : |
| PubMedSearch : Wilhelm_2009_Brain.Res.Bull_79_281 |
| PubMedID: 19480988 |