Shafiq Z

References (42)

Title : Design, Synthesis, In Vitro, and In Silico Studies of 5-(Diethylamino)-2-Formylphenyl Naphthalene-2-Sulfonate Based Thiosemicarbazones as Potent Anti-Alzheimer Agents - Farooq_2025_Arch.Pharm.(Weinheim)_358_e70050
Author(s) : Farooq U , Islam M , Batool Z , Mali SN , Jawarkar RD , Gurav SS , Alharthy RD , Senol H , Sadeghian N , Taslimi P , Shafiq Z , Schenone S
Ref : Arch Pharm (Weinheim) , 358 :e70050 , 2025
Abstract :
PubMedSearch : Farooq_2025_Arch.Pharm.(Weinheim)_358_e70050
PubMedID: 40685770

Title : Design, synthesis, and computational insights into 3-acetyl-8-methoxy coumarin hybrids as potential anti-alzheimer's agents - Zareen_2025_Sci.Rep_15_41752
Author(s) : Zareen W , Rafique M , Ahmed N , Khan MA , Tahir M , Mali SN , Sadeghian N , Taslimi P , Ismail MA , Chaudhari SY , Khan A , Senol H , Shafiq Z
Ref : Sci Rep , 15 :41752 , 2025
Abstract :
PubMedSearch : Zareen_2025_Sci.Rep_15_41752
PubMedID: 41290970

Title : New Mannich-type arylidenerhodanines as potent inhibitors of AChE and BChE: synthesis, biological evaluation, cytotoxicity and molecular modeling - Sinan Tokali_2025_RSC.Adv_15_50186
Author(s) : Sinan Tokali F , Senol H , Demir Y , Ulucay O , Ameen M , Shafiq Z
Ref : RSC Adv , 15 :50186 , 2025
Abstract :
PubMedSearch : Sinan Tokali_2025_RSC.Adv_15_50186
PubMedID: 41403678

Title : A series of 4-thiomorpholinophenyl-thiosemicarbazones as cholinesterase inhibitors with anti-neuroblastoma effects - Aftab_2025_Bioorg.Chem_168_109364
Author(s) : Aftab H , Cakir F , Turgut G , Sadeghian N , Alharthy RD , Taslimi P , Sen A , Zaki MEA , Gomha SM , Hussain J , Shafiq Z , Senol H
Ref : Bioorg Chem , 168 :109364 , 2025
Abstract :
PubMedSearch : Aftab_2025_Bioorg.Chem_168_109364
PubMedID: 41389605

Title : Design, synthesis, and computational insights into 3-acetyl-8-methoxy coumarin hybrids as potential anti-alzheimer's agents - Zareen_2025_Sci.Rep_15_41752
Author(s) : Zareen W , Rafique M , Ahmed N , Khan MA , Tahir M , Mali SN , Sadeghian N , Taslimi P , Ismail MA , Chaudhari SY , Khan A , Senol H , Shafiq Z
Ref : Sci Rep , 15 :41752 , 2025
Abstract :
PubMedSearch : Zareen_2025_Sci.Rep_15_41752
PubMedID: 41290970

Title : Dual targeting of neuroblastoma and cholinesterase by morpholino\/pyrrolidino-sulfonyl-indole thiosemicarbazones: Synthesis, characterization, enzyme inhibition, cytotoxicity, docking and dynamics studies - Batool_2025_Bioorg.Chem_167_109252
Author(s) : Batool Z , Toraman GO A , Cakir F , Topcu G , Taslimi P , Alharthy RD , Khan A , Al-Harrasi A , Shafiq Z , Senol H
Ref : Bioorg Chem , 167 :109252 , 2025
Abstract :
PubMedSearch : Batool_2025_Bioorg.Chem_167_109252
PubMedID: 41260066

Title : Synthesis, Anti-Alzheimer Evaluation and In Silico Study of 4-Methoxyphenyl)Sulfonyl Indole Hybrid Thiosemicarbazones - Ghaffar_2025_Arch.Pharm.(Weinheim)_358_e70034
Author(s) : Ghaffar U , Batool Z , Tasleem M , Sadeghian N , Taslimi P , Mali SN , Dahlous KA , Jawarkar RD , Gurav SS , Zhao X , Munir I , Shafiq Z
Ref : Arch Pharm (Weinheim) , 358 :e70034 , 2025
Abstract :
PubMedSearch : Ghaffar_2025_Arch.Pharm.(Weinheim)_358_e70034
PubMedID: 40641099

Title : Dual targeting of neuroblastoma and cholinesterase by morpholino\/pyrrolidino-sulfonyl-indole thiosemicarbazones: Synthesis, characterization, enzyme inhibition, cytotoxicity, docking and dynamics studies - Batool_2025_Bioorg.Chem_167_109252
Author(s) : Batool Z , Toraman GO A , Cakir F , Topcu G , Taslimi P , Alharthy RD , Khan A , Al-Harrasi A , Shafiq Z , Senol H
Ref : Bioorg Chem , 167 :109252 , 2025
Abstract :
PubMedSearch : Batool_2025_Bioorg.Chem_167_109252
PubMedID: 41260066

Title : Synthesis, Anti-Alzheimer Evaluation and In Silico Study of 4-Methoxyphenyl)Sulfonyl Indole Hybrid Thiosemicarbazones - Ghaffar_2025_Arch.Pharm.(Weinheim)_358_e70034
Author(s) : Ghaffar U , Batool Z , Tasleem M , Sadeghian N , Taslimi P , Mali SN , Dahlous KA , Jawarkar RD , Gurav SS , Zhao X , Munir I , Shafiq Z
Ref : Arch Pharm (Weinheim) , 358 :e70034 , 2025
Abstract :
PubMedSearch : Ghaffar_2025_Arch.Pharm.(Weinheim)_358_e70034
PubMedID: 40641099

Title : New Mannich-type arylidenerhodanines as potent inhibitors of AChE and BChE: synthesis, biological evaluation, cytotoxicity and molecular modeling - Sinan Tokali_2025_RSC.Adv_15_50186
Author(s) : Sinan Tokali F , Senol H , Demir Y , Ulucay O , Ameen M , Shafiq Z
Ref : RSC Adv , 15 :50186 , 2025
Abstract :
PubMedSearch : Sinan Tokali_2025_RSC.Adv_15_50186
PubMedID: 41403678

Title : A series of 4-thiomorpholinophenyl-thiosemicarbazones as cholinesterase inhibitors with anti-neuroblastoma effects - Aftab_2025_Bioorg.Chem_168_109364
Author(s) : Aftab H , Cakir F , Turgut G , Sadeghian N , Alharthy RD , Taslimi P , Sen A , Zaki MEA , Gomha SM , Hussain J , Shafiq Z , Senol H
Ref : Bioorg Chem , 168 :109364 , 2025
Abstract :
PubMedSearch : Aftab_2025_Bioorg.Chem_168_109364
PubMedID: 41389605

Title : Design, Synthesis, In Vitro, and In Silico Studies of 5-(Diethylamino)-2-Formylphenyl Naphthalene-2-Sulfonate Based Thiosemicarbazones as Potent Anti-Alzheimer Agents - Farooq_2025_Arch.Pharm.(Weinheim)_358_e70050
Author(s) : Farooq U , Islam M , Batool Z , Mali SN , Jawarkar RD , Gurav SS , Alharthy RD , Senol H , Sadeghian N , Taslimi P , Shafiq Z , Schenone S
Ref : Arch Pharm (Weinheim) , 358 :e70050 , 2025
Abstract :
PubMedSearch : Farooq_2025_Arch.Pharm.(Weinheim)_358_e70050
PubMedID: 40685770

Title : Dual targeting of neuroblastoma and cholinesterase by morpholino\/pyrrolidino-sulfonyl-indole thiosemicarbazones: Synthesis, characterization, enzyme inhibition, cytotoxicity, docking and dynamics studies - Batool_2025_Bioorg.Chem_167_109252
Author(s) : Batool Z , Toraman GO A , Cakir F , Topcu G , Taslimi P , Alharthy RD , Khan A , Al-Harrasi A , Shafiq Z , Senol H
Ref : Bioorg Chem , 167 :109252 , 2025
Abstract :
PubMedSearch : Batool_2025_Bioorg.Chem_167_109252
PubMedID: 41260066

Title : Synthesis, Anti-Alzheimer Evaluation and In Silico Study of 4-Methoxyphenyl)Sulfonyl Indole Hybrid Thiosemicarbazones - Ghaffar_2025_Arch.Pharm.(Weinheim)_358_e70034
Author(s) : Ghaffar U , Batool Z , Tasleem M , Sadeghian N , Taslimi P , Mali SN , Dahlous KA , Jawarkar RD , Gurav SS , Zhao X , Munir I , Shafiq Z
Ref : Arch Pharm (Weinheim) , 358 :e70034 , 2025
Abstract :
PubMedSearch : Ghaffar_2025_Arch.Pharm.(Weinheim)_358_e70034
PubMedID: 40641099

Title : Design, synthesis, and computational insights into 3-acetyl-8-methoxy coumarin hybrids as potential anti-alzheimer's agents - Zareen_2025_Sci.Rep_15_41752
Author(s) : Zareen W , Rafique M , Ahmed N , Khan MA , Tahir M , Mali SN , Sadeghian N , Taslimi P , Ismail MA , Chaudhari SY , Khan A , Senol H , Shafiq Z
Ref : Sci Rep , 15 :41752 , 2025
Abstract :
PubMedSearch : Zareen_2025_Sci.Rep_15_41752
PubMedID: 41290970

Title : Design, Synthesis, In Vitro, and In Silico Studies of 5-(Diethylamino)-2-Formylphenyl Naphthalene-2-Sulfonate Based Thiosemicarbazones as Potent Anti-Alzheimer Agents - Farooq_2025_Arch.Pharm.(Weinheim)_358_e70050
Author(s) : Farooq U , Islam M , Batool Z , Mali SN , Jawarkar RD , Gurav SS , Alharthy RD , Senol H , Sadeghian N , Taslimi P , Shafiq Z , Schenone S
Ref : Arch Pharm (Weinheim) , 358 :e70050 , 2025
Abstract :
PubMedSearch : Farooq_2025_Arch.Pharm.(Weinheim)_358_e70050
PubMedID: 40685770

Title : New Mannich-type arylidenerhodanines as potent inhibitors of AChE and BChE: synthesis, biological evaluation, cytotoxicity and molecular modeling - Sinan Tokali_2025_RSC.Adv_15_50186
Author(s) : Sinan Tokali F , Senol H , Demir Y , Ulucay O , Ameen M , Shafiq Z
Ref : RSC Adv , 15 :50186 , 2025
Abstract :
PubMedSearch : Sinan Tokali_2025_RSC.Adv_15_50186
PubMedID: 41403678

Title : A series of 4-thiomorpholinophenyl-thiosemicarbazones as cholinesterase inhibitors with anti-neuroblastoma effects - Aftab_2025_Bioorg.Chem_168_109364
Author(s) : Aftab H , Cakir F , Turgut G , Sadeghian N , Alharthy RD , Taslimi P , Sen A , Zaki MEA , Gomha SM , Hussain J , Shafiq Z , Senol H
Ref : Bioorg Chem , 168 :109364 , 2025
Abstract :
PubMedSearch : Aftab_2025_Bioorg.Chem_168_109364
PubMedID: 41389605

Title : Synthesis of 2,4-Bis(trifluoromethyl)benzaldehyde Hybrid Thiosemicarbazones as Prolyl Oligopeptidase Inhibitors for Neurodegenerative Disorders and their In-silico Analysis - Pasha_2024_Curr.Med.Chem__
Author(s) : Pasha AR , Ullah S , Halim SA , Khan A , Hussain J , F EA , Naseer MM , Eltantawy W , Al-Harrasi A , Shafiq Z
Ref : Curr Med Chem , : , 2024
Abstract :
PubMedSearch : Pasha_2024_Curr.Med.Chem__
PubMedID: 39411949

Title : Synthesis of 2,4-Bis(trifluoromethyl)benzaldehyde Hybrid Thiosemicarbazones as Prolyl Oligopeptidase Inhibitors for Neurodegenerative Disorders and their In-silico Analysis - Pasha_2024_Curr.Med.Chem__
Author(s) : Pasha AR , Ullah S , Halim SA , Khan A , Hussain J , F EA , Naseer MM , Eltantawy W , Al-Harrasi A , Shafiq Z
Ref : Curr Med Chem , : , 2024
Abstract :
PubMedSearch : Pasha_2024_Curr.Med.Chem__
PubMedID: 39411949

Title : Synthesis of 2,4-Bis(trifluoromethyl)benzaldehyde Hybrid Thiosemicarbazones as Prolyl Oligopeptidase Inhibitors for Neurodegenerative Disorders and their In-silico Analysis - Pasha_2024_Curr.Med.Chem__
Author(s) : Pasha AR , Ullah S , Halim SA , Khan A , Hussain J , F EA , Naseer MM , Eltantawy W , Al-Harrasi A , Shafiq Z
Ref : Curr Med Chem , : , 2024
Abstract :
PubMedSearch : Pasha_2024_Curr.Med.Chem__
PubMedID: 39411949

Title : 2-Oxoquinoline-based-thiosemicarbazones as multitargeting neurotherapeutics against Alzheimer's disease: In vitro and in silico studies of MAO and ChE inhibitors - Basri_2023_Arch.Pharm.(Weinheim)__e2300430
Author(s) : Basri R , Fatima S , Jalil S , Imran A , Fatima N , Syed A , Bahkali AH , Iqbal J , Shafiq Z
Ref : Arch Pharm (Weinheim) , :e2300430 , 2023
Abstract :
PubMedSearch : Basri_2023_Arch.Pharm.(Weinheim)__e2300430
PubMedID: 37718357

Title : Therapeutic potential of 1,3,4-oxadiazoles as potential lead compounds for the treatment of Alzheimer's disease - Naseem_2023_RSC.Adv_13_17526
Author(s) : Naseem S , Temirak A , Imran A , Jalil S , Fatima S , Taslimi P , Iqbal J , Tasleem M , Tahir MN , Shafiq Z
Ref : RSC Adv , 13 :17526 , 2023
Abstract :
PubMedSearch : Naseem_2023_RSC.Adv_13_17526
PubMedID: 37304812

Title : 2-Oxoquinoline-based-thiosemicarbazones as multitargeting neurotherapeutics against Alzheimer's disease: In vitro and in silico studies of MAO and ChE inhibitors - Basri_2023_Arch.Pharm.(Weinheim)__e2300430
Author(s) : Basri R , Fatima S , Jalil S , Imran A , Fatima N , Syed A , Bahkali AH , Iqbal J , Shafiq Z
Ref : Arch Pharm (Weinheim) , :e2300430 , 2023
Abstract :
PubMedSearch : Basri_2023_Arch.Pharm.(Weinheim)__e2300430
PubMedID: 37718357

Title : Synthesis, biological evaluation, and molecular docking study of xanthene-linked thiosemicarbazones as cholinesterase inhibitors - Naseem_2023_J.Biomol.Struct.Dyn__1
Author(s) : Naseem S , Khan S , Hussain S , Mirza MU , Ashraf M , Shafiq Z , Trant JF
Ref : J Biomol Struct Dyn , :1 , 2023
Abstract :
PubMedSearch : Naseem_2023_J.Biomol.Struct.Dyn__1
PubMedID: 37948312

Title : Therapeutic potential of 1,3,4-oxadiazoles as potential lead compounds for the treatment of Alzheimer's disease - Naseem_2023_RSC.Adv_13_17526
Author(s) : Naseem S , Temirak A , Imran A , Jalil S , Fatima S , Taslimi P , Iqbal J , Tasleem M , Tahir MN , Shafiq Z
Ref : RSC Adv , 13 :17526 , 2023
Abstract :
PubMedSearch : Naseem_2023_RSC.Adv_13_17526
PubMedID: 37304812

Title : 2-Oxoquinoline-based-thiosemicarbazones as multitargeting neurotherapeutics against Alzheimer's disease: In vitro and in silico studies of MAO and ChE inhibitors - Basri_2023_Arch.Pharm.(Weinheim)__e2300430
Author(s) : Basri R , Fatima S , Jalil S , Imran A , Fatima N , Syed A , Bahkali AH , Iqbal J , Shafiq Z
Ref : Arch Pharm (Weinheim) , :e2300430 , 2023
Abstract :
PubMedSearch : Basri_2023_Arch.Pharm.(Weinheim)__e2300430
PubMedID: 37718357

Title : Therapeutic potential of 1,3,4-oxadiazoles as potential lead compounds for the treatment of Alzheimer's disease - Naseem_2023_RSC.Adv_13_17526
Author(s) : Naseem S , Temirak A , Imran A , Jalil S , Fatima S , Taslimi P , Iqbal J , Tasleem M , Tahir MN , Shafiq Z
Ref : RSC Adv , 13 :17526 , 2023
Abstract :
PubMedSearch : Naseem_2023_RSC.Adv_13_17526
PubMedID: 37304812

Title : Synthesis, biological evaluation, and molecular docking study of xanthene-linked thiosemicarbazones as cholinesterase inhibitors - Naseem_2023_J.Biomol.Struct.Dyn__1
Author(s) : Naseem S , Khan S , Hussain S , Mirza MU , Ashraf M , Shafiq Z , Trant JF
Ref : J Biomol Struct Dyn , :1 , 2023
Abstract :
PubMedSearch : Naseem_2023_J.Biomol.Struct.Dyn__1
PubMedID: 37948312

Title : Synthesis, biological evaluation, and molecular docking study of xanthene-linked thiosemicarbazones as cholinesterase inhibitors - Naseem_2023_J.Biomol.Struct.Dyn__1
Author(s) : Naseem S , Khan S , Hussain S , Mirza MU , Ashraf M , Shafiq Z , Trant JF
Ref : J Biomol Struct Dyn , :1 , 2023
Abstract :
PubMedSearch : Naseem_2023_J.Biomol.Struct.Dyn__1
PubMedID: 37948312

Title : Synthesis and evaluation of novel xanthene-based thiazoles as potential antidiabetic agents - Naseem_2022_Arch.Pharm.(Weinheim)__e2200356
Author(s) : Naseem S , Shafiq Z , Taslimi P , Hussain S , Taskin-Tok T , Kisa D , Saeed A , Temirak A , Tahir MN , Rauf K , El-Gokha A
Ref : Arch Pharm (Weinheim) , :e2200356 , 2022
Abstract :
PubMedSearch : Naseem_2022_Arch.Pharm.(Weinheim)__e2200356
PubMedID: 36220614

Title : Synthesis and evaluation of novel xanthene-based thiazoles as potential antidiabetic agents - Naseem_2022_Arch.Pharm.(Weinheim)__e2200356
Author(s) : Naseem S , Shafiq Z , Taslimi P , Hussain S , Taskin-Tok T , Kisa D , Saeed A , Temirak A , Tahir MN , Rauf K , El-Gokha A
Ref : Arch Pharm (Weinheim) , :e2200356 , 2022
Abstract :
PubMedSearch : Naseem_2022_Arch.Pharm.(Weinheim)__e2200356
PubMedID: 36220614

Title : Synthesis and evaluation of novel xanthene-based thiazoles as potential antidiabetic agents - Naseem_2022_Arch.Pharm.(Weinheim)__e2200356
Author(s) : Naseem S , Shafiq Z , Taslimi P , Hussain S , Taskin-Tok T , Kisa D , Saeed A , Temirak A , Tahir MN , Rauf K , El-Gokha A
Ref : Arch Pharm (Weinheim) , :e2200356 , 2022
Abstract :
PubMedSearch : Naseem_2022_Arch.Pharm.(Weinheim)__e2200356
PubMedID: 36220614

Title : Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone - Riaz_2021_Bioorg.Chem_114_105069
Author(s) : Riaz MT , Yaqub M , Shafiq Z , Ashraf A , Khalid M , Taslimi P , Tas R , Tuzun B , Gulcin I
Ref : Bioorg Chem , 114 :105069 , 2021
Abstract :
PubMedSearch : Riaz_2021_Bioorg.Chem_114_105069
PubMedID: 34134033

Title : Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone - Riaz_2021_Bioorg.Chem_114_105069
Author(s) : Riaz MT , Yaqub M , Shafiq Z , Ashraf A , Khalid M , Taslimi P , Tas R , Tuzun B , Gulcin I
Ref : Bioorg Chem , 114 :105069 , 2021
Abstract :
PubMedSearch : Riaz_2021_Bioorg.Chem_114_105069
PubMedID: 34134033

Title : Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone - Riaz_2021_Bioorg.Chem_114_105069
Author(s) : Riaz MT , Yaqub M , Shafiq Z , Ashraf A , Khalid M , Taslimi P , Tas R , Tuzun B , Gulcin I
Ref : Bioorg Chem , 114 :105069 , 2021
Abstract :
PubMedSearch : Riaz_2021_Bioorg.Chem_114_105069
PubMedID: 34134033

Title : Synthesis, bioactivity and binding energy calculations of novel 3-ethoxysalicylaldehyde based thiosemicarbazone derivatives - Ishaq_2020_Bioorg.Chem_100_103924
Author(s) : Ishaq M , Taslimi P , Shafiq Z , Khan S , Ekhteiari Salmas R , Zangeneh MM , Saeed A , Zangeneh A , Sadeghian N , Asari A , Mohamad H
Ref : Bioorg Chem , 100 :103924 , 2020
Abstract :
PubMedSearch : Ishaq_2020_Bioorg.Chem_100_103924
PubMedID: 32442818

Title : Probing 4-(diethylamino)-salicylaldehyde-based thiosemicarbazones as multi-target directed ligands against cholinesterases, carbonic anhydrases and alpha-glycosidase enzymes - Hashmi_2020_Bioorg.Chem_107_104554
Author(s) : Hashmi S , Khan S , Shafiq Z , Taslimi P , Ishaq M , Sadeghian N , Karaman HS , Akhtar N , Islam M , Asari A , Mohamad H , Gulcin I
Ref : Bioorg Chem , 107 :104554 , 2020
Abstract :
PubMedSearch : Hashmi_2020_Bioorg.Chem_107_104554
PubMedID: 33383322

Title : Probing 4-(diethylamino)-salicylaldehyde-based thiosemicarbazones as multi-target directed ligands against cholinesterases, carbonic anhydrases and alpha-glycosidase enzymes - Hashmi_2020_Bioorg.Chem_107_104554
Author(s) : Hashmi S , Khan S , Shafiq Z , Taslimi P , Ishaq M , Sadeghian N , Karaman HS , Akhtar N , Islam M , Asari A , Mohamad H , Gulcin I
Ref : Bioorg Chem , 107 :104554 , 2020
Abstract :
PubMedSearch : Hashmi_2020_Bioorg.Chem_107_104554
PubMedID: 33383322

Title : Synthesis, bioactivity and binding energy calculations of novel 3-ethoxysalicylaldehyde based thiosemicarbazone derivatives - Ishaq_2020_Bioorg.Chem_100_103924
Author(s) : Ishaq M , Taslimi P , Shafiq Z , Khan S , Ekhteiari Salmas R , Zangeneh MM , Saeed A , Zangeneh A , Sadeghian N , Asari A , Mohamad H
Ref : Bioorg Chem , 100 :103924 , 2020
Abstract :
PubMedSearch : Ishaq_2020_Bioorg.Chem_100_103924
PubMedID: 32442818

Title : Synthesis, bioactivity and binding energy calculations of novel 3-ethoxysalicylaldehyde based thiosemicarbazone derivatives - Ishaq_2020_Bioorg.Chem_100_103924
Author(s) : Ishaq M , Taslimi P , Shafiq Z , Khan S , Ekhteiari Salmas R , Zangeneh MM , Saeed A , Zangeneh A , Sadeghian N , Asari A , Mohamad H
Ref : Bioorg Chem , 100 :103924 , 2020
Abstract :
PubMedSearch : Ishaq_2020_Bioorg.Chem_100_103924
PubMedID: 32442818

Title : Probing 4-(diethylamino)-salicylaldehyde-based thiosemicarbazones as multi-target directed ligands against cholinesterases, carbonic anhydrases and alpha-glycosidase enzymes - Hashmi_2020_Bioorg.Chem_107_104554
Author(s) : Hashmi S , Khan S , Shafiq Z , Taslimi P , Ishaq M , Sadeghian N , Karaman HS , Akhtar N , Islam M , Asari A , Mohamad H , Gulcin I
Ref : Bioorg Chem , 107 :104554 , 2020
Abstract :
PubMedSearch : Hashmi_2020_Bioorg.Chem_107_104554
PubMedID: 33383322