| Title : Randomized evaluation of the loss-of-function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics - Lewis_2024_Clin.Transl.Sci_17_e70079 |
| Author(s) : Lewis JP , Ryan KA , Streeten EA , Whitlatch HB , Daue M , Tanner K , Perry JA , O'Connell JR , Shuldiner AR , Mitchell BD |
| Ref : Clin Transl Sci , 17 :e70079 , 2024 |
| Abstract : |
| PubMedSearch : Lewis_2024_Clin.Transl.Sci_17_e70079 |
| PubMedID: 39576732 |
| Title : A Missense Variant Arg611Cys in LIPE which Encodes Hormone Sensitive Lipase Decreases Lipolysis and Increases Risk of Type 2 Diabetes in American Indians - Muller_2021_Diabetes.Metab.Res.Rev__e3504 |
| Author(s) : Muller YL , Sutherland J , Nair AK , Koroglu C , Kobes S , Knowler WC , Van Hout CV , Shuldiner AR , Hanson RL , Bogardus C , Baier LJ |
| Ref : Diabetes Metab Res Rev , :e3504 , 2021 |
| Abstract : |
| PubMedSearch : Muller_2021_Diabetes.Metab.Res.Rev__e3504 |
| PubMedID: 34655148 |
| Gene_locus related to this paper: human-LIPE |
| Title : Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response - Backman_2017_Pharmacogenet.Genomics_27_159 |
| Author(s) : Backman JD , O'Connell JR , Tanner K , Peer CJ , Figg WD , Spencer SD , Mitchell BD , Shuldiner AR , Yerges-Armstrong LM , Horenstein RB , Lewis JP |
| Ref : Pharmacogenet Genomics , 27 :159 , 2017 |
| Abstract : |
| PubMedSearch : Backman_2017_Pharmacogenet.Genomics_27_159 |
| PubMedID: 28207573 |
| Title : Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes - Albert_2014_N.Engl.J.Med_370_2307 |
| Author(s) : Albert JS , Yerges-Armstrong LM , Horenstein RB , Pollin TI , Sreenivasan UT , Chai S , Blaner WS , Snitker S , O'Connell JR , Gong DW , Breyer RJ, 3rd , Ryan AS , McLenithan JC , Shuldiner AR , Sztalryd C , Damcott CM |
| Ref : N Engl J Med , 370 :2307 , 2014 |
| Abstract : |
| PubMedSearch : Albert_2014_N.Engl.J.Med_370_2307 |
| PubMedID: 24848981 |
| Gene_locus related to this paper: human-LIPE |
| Title : The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response - Lewis_2013_Pharmacogenet.Genomics_23_1 |
| Author(s) : Lewis JP , Horenstein RB , Ryan K , O'Connell JR , Gibson Q , Mitchell BD , Tanner K , Chai S , Bliden KP , Tantry US , Peer CJ , Figg WD , Spencer SD , Pacanowski MA , Gurbel PA , Shuldiner AR |
| Ref : Pharmacogenet Genomics , 23 :1 , 2013 |
| Abstract : |
| PubMedSearch : Lewis_2013_Pharmacogenet.Genomics_23_1 |
| PubMedID: 23111421 |
| Gene_locus related to this paper: human-CES1 |