Title : Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif - Pisani_2016_Molecules_21_ |
Author(s) : Pisani L , Farina R , Soto-Otero R , Denora N , Mangiatordi GF , Nicolotti O , Mendez-Alvarez E , Altomare CD , Catto M , Carotti A |
Ref : Molecules , 21 : , 2016 |
Abstract : |
PubMedSearch : Pisani_2016_Molecules_21_ |
PubMedID: 26999091 |
Title : Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents - Pisani_2016_J.Med.Chem_59_6791 |
Author(s) : Pisani L , Farina R , Catto M , Iacobazzi RM , Nicolotti O , Cellamare S , Mangiatordi GF , Denora N , Soto-Otero R , Siragusa L , Altomare CD , Carotti A |
Ref : Journal of Medicinal Chemistry , 59 :6791 , 2016 |
Abstract : |
PubMedSearch : Pisani_2016_J.Med.Chem_59_6791 |
PubMedID: 27347731 |
Title : Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases - Farina_2015_J.Med.Chem_58_5561 |
Author(s) : Farina R , Pisani L , Catto M , Nicolotti O , Gadaleta D , Denora N , Soto-Otero R , Mendez-Alvarez E , Passos CS , Muncipinto G , Altomare CD , Nurisso A , Carrupt PA , Carotti A |
Ref : Journal of Medicinal Chemistry , 58 :5561 , 2015 |
Abstract : |
PubMedSearch : Farina_2015_J.Med.Chem_58_5561 |
PubMedID: 26107513 |
Title : Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors - Carotti_2006_Bioorg.Med.Chem_14_7205 |
Author(s) : Carotti A , de Candia M , Catto M , Borisova TN , Varlamov AV , Mendez-Alvarez E , Soto-Otero R , Voskressensky LG , Altomare CD |
Ref : Bioorganic & Medicinal Chemistry , 14 :7205 , 2006 |
Abstract : |
PubMedSearch : Carotti_2006_Bioorg.Med.Chem_14_7205 |
PubMedID: 16843666 |