Report for Catto M

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References (51)

Title : Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults - Samarelli_2024_Eur.J.Med.Chem_270_116353
Author(s) : Samarelli F , Purgatorio R , Lopopolo G , Deruvo C , Catto M , Andresini M , Carrieri A , Nicolotti O , De Palma A , Miniero DV , de Candia M , Altomare CD
Ref : Eur Journal of Medicinal Chemistry , 270 :116353 , 2024
Abstract : Samarelli_2024_Eur.J.Med.Chem_270_116353
ESTHER : Samarelli_2024_Eur.J.Med.Chem_270_116353
PubMedSearch : Samarelli_2024_Eur.J.Med.Chem_270_116353
PubMedID: 38579622

Title : Investigation on Novel E\/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity - Paolino_2023_Molecules_28_
Author(s) : Paolino M , de Candia M , Purgatorio R , Catto M , Saletti M , Tondo AR , Nicolotti O , Cappelli A , Brizzi A , Mugnaini C , Corelli F , Altomare CD
Ref : Molecules , 28 : , 2023
Abstract : Paolino_2023_Molecules_28_
ESTHER : Paolino_2023_Molecules_28_
PubMedSearch : Paolino_2023_Molecules_28_
PubMedID: 37570828

Title : Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease - Hafez_2023_J.Enzyme.Inhib.Med.Chem_38_2175821
Author(s) : Hafez DE , Dubiel M , La Spada G , Catto M , Reiner-Link D , Syu YT , Abdel-Halim M , Hwang TL , Stark H , Abadi AH
Ref : J Enzyme Inhib Med Chem , 38 :2175821 , 2023
Abstract : Hafez_2023_J.Enzyme.Inhib.Med.Chem_38_2175821
ESTHER : Hafez_2023_J.Enzyme.Inhib.Med.Chem_38_2175821
PubMedSearch : Hafez_2023_J.Enzyme.Inhib.Med.Chem_38_2175821
PubMedID: 36789662

Title : Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT(6) receptor interaction - Asproni_2023_Bioorg.Med.Chem_84_117256
Author(s) : Asproni B , Catto M , Loriga G , Murineddu G , Corona P , Purgatorio R , Cichero E , Fossa P , Scarano N , Martinez AL , Brea J , Pinna GA
Ref : Bioorganic & Medicinal Chemistry , 84 :117256 , 2023
Abstract : Asproni_2023_Bioorg.Med.Chem_84_117256
ESTHER : Asproni_2023_Bioorg.Med.Chem_84_117256
PubMedSearch : Asproni_2023_Bioorg.Med.Chem_84_117256
PubMedID: 37003157

Title : In-vitro and in-silico studies of annelated 1,4,7,8-tetrahydroazocine ester derivatives as nanomolar selective inhibitors of human butyrylcholinesterase - de Candia_2023_Chem.Biol.Interact_14ChEPon_110741
Author(s) : de Candia M , Titov AA , Viayna A , Kulikova LN , Purgatorio R , Piergiovanni B , Niso M , Catto M , Voskressensky LG , Luque FJ , Altomare CD
Ref : Chemico-Biological Interactions , :110741 , 2023
Abstract : de Candia_2023_Chem.Biol.Interact_14ChEPon_110741
ESTHER : de Candia_2023_Chem.Biol.Interact_14ChEPon_110741
PubMedSearch : de Candia_2023_Chem.Biol.Interact_14ChEPon_110741
PubMedID: 37839515

Title : Chemical and Biological Evaluation of Novel 1H-Chromeno[3,2-c]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity - Kulikova_2023_Int.J.Mol.Sci_24_
Author(s) : Kulikova LN , Purgatorio R , Beloglazkin AA , Tafeenko VA , Reza RG , Levickaya DD , Sblano S , Boccarelli A , de Candia M , Catto M , Voskressensky LG , Altomare CD
Ref : Int J Mol Sci , 24 : , 2023
Abstract : Kulikova_2023_Int.J.Mol.Sci_24_
ESTHER : Kulikova_2023_Int.J.Mol.Sci_24_
PubMedSearch : Kulikova_2023_Int.J.Mol.Sci_24_
PubMedID: 37175433

Title : Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease - Tonelli_2023_Eur.J.Med.Chem_250_115169
Author(s) : Tonelli M , Catto M , Sabate R , Francesconi V , Laurini E , Pricl S , Pisani L , Miniero DV , Liuzzi GM , Gatta E , Relini A , Gavin R , Del Rio JA , Sparatore F , Carotti A
Ref : Eur Journal of Medicinal Chemistry , 250 :115169 , 2023
Abstract : Tonelli_2023_Eur.J.Med.Chem_250_115169
ESTHER : Tonelli_2023_Eur.J.Med.Chem_250_115169
PubMedSearch : Tonelli_2023_Eur.J.Med.Chem_250_115169
PubMedID: 36753881

Title : A twenty-year journey exploring coumarin-based derivatives as bioactive molecules - Pisani_2022_Front.Chem_10_1002547
Author(s) : Pisani L , Catto M , Muncipinto G , Nicolotti O , Carrieri A , Rullo M , Stefanachi A , Leonetti F , Altomare CD
Ref : Front Chem , 10 :1002547 , 2022
Abstract : Pisani_2022_Front.Chem_10_1002547
ESTHER : Pisani_2022_Front.Chem_10_1002547
PubMedSearch : Pisani_2022_Front.Chem_10_1002547
PubMedID: 36300022

Title : Towards Alzheimer's disease-related targets: One-pot Cu(I)- mediated synthesis of new nitroindazolyltriazoles - Eddahmi_2022_Bioorg.Chem_130_106261
Author(s) : Eddahmi M , La Spada G , Hafid A , Khouili M , Catto M , Bouissane L
Ref : Bioorg Chem , 130 :106261 , 2022
Abstract : Eddahmi_2022_Bioorg.Chem_130_106261
ESTHER : Eddahmi_2022_Bioorg.Chem_130_106261
PubMedSearch : Eddahmi_2022_Bioorg.Chem_130_106261
PubMedID: 36399866

Title : Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity - Titov_2022_Molecules_27_
Author(s) : Titov AA , Purgatorio R , Obydennik AY , Listratova AV , Borisova TN , de Candia M , Catto M , Altomare CD , Varlamov AV , Voskressensky LG
Ref : Molecules , 27 : , 2022
Abstract : Titov_2022_Molecules_27_
ESTHER : Titov_2022_Molecules_27_
PubMedSearch : Titov_2022_Molecules_27_
PubMedID: 36234811

Title : N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases - Bautista-Aguilera_2022_Molecules_27_
Author(s) : Bautista-Aguilera M , Alonso JM , Catto M , Iriepa I , Knez D , Gobec S , Marco-Contelles J
Ref : Molecules , 27 : , 2022
Abstract : Bautista-Aguilera_2022_Molecules_27_
ESTHER : Bautista-Aguilera_2022_Molecules_27_
PubMedSearch : Bautista-Aguilera_2022_Molecules_27_
PubMedID: 36364263

Title : Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors - Paolino_2022_RSC.Med.Chem_13_873
Author(s) : Paolino M , Rullo M , Maramai S , de Candia M , Pisani L , Catto M , Mugnaini C , Brizzi A , Cappelli A , Olivucci M , Corelli F , Altomare CD
Ref : RSC Med Chem , 13 :873 , 2022
Abstract : Paolino_2022_RSC.Med.Chem_13_873
ESTHER : Paolino_2022_RSC.Med.Chem_13_873
PubMedSearch : Paolino_2022_RSC.Med.Chem_13_873
PubMedID: 35923722

Title : Novel Phenothiazine\/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease - Carocci_2022_Antioxidants.(Basel)_11_
Author(s) : Carocci A , Barbarossa A , Leuci R , Carrieri A , Brunetti L , Laghezza A , Catto M , Limongelli F , Chaves S , Tortorella P , Altomare CD , Santos MA , Loiodice F , Piemontese L
Ref : Antioxidants (Basel) , 11 : , 2022
Abstract : Carocci_2022_Antioxidants.(Basel)_11_
ESTHER : Carocci_2022_Antioxidants.(Basel)_11_
PubMedSearch : Carocci_2022_Antioxidants.(Basel)_11_
PubMedID: 36139705

Title : Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease - Brunetti_2022_Eur.J.Med.Chem_237_114358
Author(s) : Brunetti L , Leuci R , Carrieri A , Catto M , Occhineri S , Vinci G , Gambacorta L , Baltrukevich H , Chaves S , Laghezza A , Altomare CD , Tortorella P , Santos MA , Loiodice F , Piemontese L
Ref : Eur Journal of Medicinal Chemistry , 237 :114358 , 2022
Abstract : Brunetti_2022_Eur.J.Med.Chem_237_114358
ESTHER : Brunetti_2022_Eur.J.Med.Chem_237_114358
PubMedSearch : Brunetti_2022_Eur.J.Med.Chem_237_114358
PubMedID: 35462163

Title : A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) - Leuci_2022_Molecules_27_
Author(s) : Leuci R , Brunetti L , Laghezza A , Piemontese L , Carrieri A , Pisani L , Tortorella P , Catto M , Loiodice F
Ref : Molecules , 27 : , 2022
Abstract : Leuci_2022_Molecules_27_
ESTHER : Leuci_2022_Molecules_27_
PubMedSearch : Leuci_2022_Molecules_27_
PubMedID: 35164223

Title : Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases - Purgatorio_2022_Molecules_27_
Author(s) : Purgatorio R , Gambacorta N , Samarelli F , Lopopolo G , de Candia M , Catto M , Nicolotti O , Altomare CD
Ref : Molecules , 27 : , 2022
Abstract : Purgatorio_2022_Molecules_27_
ESTHER : Purgatorio_2022_Molecules_27_
PubMedSearch : Purgatorio_2022_Molecules_27_
PubMedID: 35807514

Title : Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures - Ekstrom_2022_ACS.Med.Chem.Lett_13_499
Author(s) : Ekstrom F , Gottinger A , Forsgren N , Catto M , Iacovino LG , Pisani P , Binda C
Ref : ACS Med Chem Lett , 13 :499 , 2022
Abstract : Ekstrom_2022_ACS.Med.Chem.Lett_13_499
ESTHER : Ekstrom_2022_ACS.Med.Chem.Lett_13_499
PubMedSearch : Ekstrom_2022_ACS.Med.Chem.Lett_13_499
PubMedID: 35300078
Gene_locus related to this paper: mouse-ACHE

Title : Multitarget Biological Profiling of New Naphthoquinone and Anthraquinone-Based Derivatives for the Treatment of Alzheimer's Disease - Campora_2021_ACS.Chem.Neurosci__
Author(s) : Campora M , Canale C , Gatta E , Tasso B , Laurini E , Relini A , Pricl S , Catto M , Tonelli M
Ref : ACS Chem Neurosci , : , 2021
Abstract : Campora_2021_ACS.Chem.Neurosci__
ESTHER : Campora_2021_ACS.Chem.Neurosci__
PubMedSearch : Campora_2021_ACS.Chem.Neurosci__
PubMedID: 33428389

Title : Synthesis and biological evaluation of dantrolene-like hydrazide and hydrazone analogues as multitarget agents for neurodegenerative diseases - Bolognino_2021_ChemMedChem__
Author(s) : Bolognino I , Giangregorio N , Tonazzi A , Martinez AL , Altomare CD , Loza MI , Sablone S , Cellamare S , Catto M
Ref : ChemMedChem , : , 2021
Abstract : Bolognino_2021_ChemMedChem__
ESTHER : Bolognino_2021_ChemMedChem__
PubMedSearch : Bolognino_2021_ChemMedChem__
PubMedID: 34047061

Title : Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential - Nevskaya_2021_Molecules_26_
Author(s) : Nevskaya AA , Anikina LV , Purgatorio R , Catto M , Nicolotti O , de Candia M , Pisani L , Borisova TN , Miftyakhova AR , Varlamov AV , Nevskaya EY , Borisov RS , Voskressensky LG , Altomare CD
Ref : Molecules , 26 : , 2021
Abstract : Nevskaya_2021_Molecules_26_
ESTHER : Nevskaya_2021_Molecules_26_
PubMedSearch : Nevskaya_2021_Molecules_26_
PubMedID: 33445600

Title : Evaluation of water-soluble Mannich base prodrugs of 2,3,4,5-tetrahydroazepino[4,3-b]indol-1(6H)-one as multitarget-directed agents for Alzheimer's disease - Purgatorio_2021_ChemMedChem_16_589
Author(s) : Purgatorio R , de Candia M , Catto M , Rullo M , Pisani L , Denora N , Carrieri A , Nevskaya AA , Voskressensky LG , Altomare CD
Ref : ChemMedChem , 16 :589 , 2021
Abstract : Purgatorio_2021_ChemMedChem_16_589
ESTHER : Purgatorio_2021_ChemMedChem_16_589
PubMedSearch : Purgatorio_2021_ChemMedChem_16_589
PubMedID: 33156950

Title : Synthesis of 8-phenyl substituted 3-benzazecines with allene moiety, their thermal rearrangement and evaluation as acetylcholinesterase inhibitors - Kobzev_2021_Mol.Divers__
Author(s) : Kobzev MS , Titov AA , Alexandrova EV , Purgatorio R , Catto M , Sorokina EA , Borisova TN , Varlamov AV , Altomare CD , Voskressensky LG
Ref : Mol Divers , : , 2021
Abstract : Kobzev_2021_Mol.Divers__
ESTHER : Kobzev_2021_Mol.Divers__
PubMedSearch : Kobzev_2021_Mol.Divers__
PubMedID: 33538985

Title : First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease - Purgatorio_2021_Molecules_26_
Author(s) : Purgatorio R , Gambacorta N , de Candia M , Catto M , Rullo M , Pisani L , Nicolotti O , Altomare CD
Ref : Molecules , 26 : , 2021
Abstract : Purgatorio_2021_Molecules_26_
ESTHER : Purgatorio_2021_Molecules_26_
PubMedSearch : Purgatorio_2021_Molecules_26_
PubMedID: 34500640

Title : Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents - Titov_2021_ACS.Chem.Neurosci__
Author(s) : Titov AA , Kobzev MS , Catto M , de Candia M , Gambacorta N , Denora N , Pisani L , Nicolotti O , Borisova TN , Varlamov AV , Voskressensky LG , Altomare CD
Ref : ACS Chem Neurosci , : , 2021
Abstract : Titov_2021_ACS.Chem.Neurosci__
ESTHER : Titov_2021_ACS.Chem.Neurosci__
PubMedSearch : Titov_2021_ACS.Chem.Neurosci__
PubMedID: 33395258

Title : Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multi-target Ligands Directed towards Relevant Alzheimer's Targets - Purgatorio_2020_ChemMedChem_15_1947
Author(s) : Purgatorio R , Kulikova L , Pisani L , Catto M , de Candia M , Carrieri A , Cellamare S , De Palma A , Beloglazkin A , Raesi GR , Voskressensky L , Altomare CD
Ref : ChemMedChem , 15 :1947 , 2020
Abstract : Purgatorio_2020_ChemMedChem_15_1947
ESTHER : Purgatorio_2020_ChemMedChem_15_1947
PubMedSearch : Purgatorio_2020_ChemMedChem_15_1947
PubMedID: 32716595

Title : First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease - Guieu_2020_Molecules_26_
Author(s) : Guieu B , Lecoutey C , Legay R , Davis A , Sopkova de Oliveira Santos J , Altomare CD , Catto M , Rochais C , Dallemagne P
Ref : Molecules , 26 : , 2020
Abstract : Guieu_2020_Molecules_26_
ESTHER : Guieu_2020_Molecules_26_
PubMedSearch : Guieu_2020_Molecules_26_
PubMedID: 33375412

Title : Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor - Catto_2020_ACS.Med.Chem.Lett_11_869
Author(s) : Catto M , Pisani L , De la Mora E , Belviso BD , Mangiatordi GF , Pinto A , Palma A , Denora N , Caliandro R , Colletier JP , Silman I , Nicolotti O , Altomare CD
Ref : ACS Med Chem Lett , 11 :869 , 2020
Abstract : Catto_2020_ACS.Med.Chem.Lett_11_869
ESTHER : Catto_2020_ACS.Med.Chem.Lett_11_869
PubMedSearch : Catto_2020_ACS.Med.Chem.Lett_11_869
PubMedID: 32435398

Title : Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 - Oukoloff_2019_Eur.J.Med.Chem_168_58
Author(s) : Oukoloff K , Coquelle N , Bartolini M , Naldi M , Le Guevel R , Bach S , Josselin B , Ruchaud S , Catto M , Pisani L , Denora N , Iacobazzi RM , Silman I , Sussman JL , Buron F , Colletier JP , Jean L , Routier S , Renard PY
Ref : Eur Journal of Medicinal Chemistry , 168 :58 , 2019
Abstract : Oukoloff_2019_Eur.J.Med.Chem_168_58
ESTHER : Oukoloff_2019_Eur.J.Med.Chem_168_58
PubMedSearch : Oukoloff_2019_Eur.J.Med.Chem_168_58
PubMedID: 30798053
Gene_locus related to this paper: torca-ACHE

Title : Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2H-Chromen-2-ones - Rullo_2019_Molecules_24_
Author(s) : Rullo M , Catto M , Carrieri A , de Candia M , Altomare CD , Pisani L
Ref : Molecules , 24 : , 2019
Abstract : Rullo_2019_Molecules_24_
ESTHER : Rullo_2019_Molecules_24_
PubMedSearch : Rullo_2019_Molecules_24_
PubMedID: 31835376

Title : A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer's Disease - Bolognino_2019_Molecules_24_
Author(s) : Bolognino I , Giangregorio N , Pisani L , de Candia M , Purgatorio R , Tonazzi A , Altomare CD , Cellamare S , Catto M
Ref : Molecules , 24 : , 2019
Abstract : Bolognino_2019_Molecules_24_
ESTHER : Bolognino_2019_Molecules_24_
PubMedSearch : Bolognino_2019_Molecules_24_
PubMedID: 31775359

Title : Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease - Purgatorio_2019_Eur.J.Med.Chem_177_414
Author(s) : Purgatorio R , de Candia M , Catto M , Carrieri A , Pisani L , De Palma A , Toma M , Ivanova OA , Voskressensky LG , Altomare CD
Ref : Eur Journal of Medicinal Chemistry , 177 :414 , 2019
Abstract : Purgatorio_2019_Eur.J.Med.Chem_177_414
ESTHER : Purgatorio_2019_Eur.J.Med.Chem_177_414
PubMedSearch : Purgatorio_2019_Eur.J.Med.Chem_177_414
PubMedID: 31158754

Title : Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds - Stefanachi_2018_Molecules_23_
Author(s) : Stefanachi A , Leonetti F , Pisani L , Catto M , Carotti A
Ref : Molecules , 23 : , 2018
Abstract : Stefanachi_2018_Molecules_23_
ESTHER : Stefanachi_2018_Molecules_23_
PubMedSearch : Stefanachi_2018_Molecules_23_
PubMedID: 29382051

Title : Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer's Disease - Piemontese_2018_Molecules_23_
Author(s) : Piemontese L , Vitucci G , Catto M , Laghezza A , Perna FM , Rullo M , Loiodice F , Capriati V , Solfrizzo M
Ref : Molecules , 23 : , 2018
Abstract : Piemontese_2018_Molecules_23_
ESTHER : Piemontese_2018_Molecules_23_
PubMedSearch : Piemontese_2018_Molecules_23_
PubMedID: 30158491

Title : Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors - Pisani_2018_Eur.J.Med.Chem_161_292
Author(s) : Pisani L , Iacobazzi RM , Catto M , Rullo M , Farina R , Denora N , Cellamare S , Altomare CD
Ref : Eur Journal of Medicinal Chemistry , 161 :292 , 2018
Abstract : Pisani_2018_Eur.J.Med.Chem_161_292
ESTHER : Pisani_2018_Eur.J.Med.Chem_161_292
PubMedSearch : Pisani_2018_Eur.J.Med.Chem_161_292
PubMedID: 30366255

Title : Discovery of Potent Dual Binding Site Acetylcholinesterase Inhibitors via Homo- and Heterodimerization of Coumarin-Based Moieties - Pisani_2017_ChemMedChem_12_1349
Author(s) : Pisani L , Catto M , De Palma A , Farina R , Cellamare S , Altomare CD
Ref : ChemMedChem , 12 :1349 , 2017
Abstract : Pisani_2017_ChemMedChem_12_1349
ESTHER : Pisani_2017_ChemMedChem_12_1349
PubMedSearch : Pisani_2017_ChemMedChem_12_1349
PubMedID: 28570763

Title : Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl)hydrazone: A water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity - Pisani_2017_Eur.J.Pharm.Sci_109_381
Author(s) : Pisani L , De Palma A , Giangregorio N , Miniero DV , Pesce P , Nicolotti O , Campagna F , Altomare CD , Catto M
Ref : Eur J Pharm Sci , 109 :381 , 2017
Abstract : Pisani_2017_Eur.J.Pharm.Sci_109_381
ESTHER : Pisani_2017_Eur.J.Pharm.Sci_109_381
PubMedSearch : Pisani_2017_Eur.J.Pharm.Sci_109_381
PubMedID: 28801274

Title : 3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes - Park_2017_Bioorg.Med.Chem.Lett_27_1179
Author(s) : Park B , Nam JH , Kim JH , Kim HJ , Onnis V , Balboni G , Lee KT , Park JH , Catto M , Carotti A , Lee JY
Ref : Bioorganic & Medicinal Chemistry Lett , 27 :1179 , 2017
Abstract : Park_2017_Bioorg.Med.Chem.Lett_27_1179
ESTHER : Park_2017_Bioorg.Med.Chem.Lett_27_1179
PubMedSearch : Park_2017_Bioorg.Med.Chem.Lett_27_1179
PubMedID: 28189420

Title : Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents - Pisani_2016_J.Med.Chem_59_6791
Author(s) : Pisani L , Farina R , Catto M , Iacobazzi RM , Nicolotti O , Cellamare S , Mangiatordi GF , Denora N , Soto-Otero R , Siragusa L , Altomare CD , Carotti A
Ref : Journal of Medicinal Chemistry , 59 :6791 , 2016
Abstract : Pisani_2016_J.Med.Chem_59_6791
ESTHER : Pisani_2016_J.Med.Chem_59_6791
PubMedSearch : Pisani_2016_J.Med.Chem_59_6791
PubMedID: 27347731

Title : Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif - Pisani_2016_Molecules_21_
Author(s) : Pisani L , Farina R , Soto-Otero R , Denora N , Mangiatordi GF , Nicolotti O , Mendez-Alvarez E , Altomare CD , Catto M , Carotti A
Ref : Molecules , 21 : , 2016
Abstract : Pisani_2016_Molecules_21_
ESTHER : Pisani_2016_Molecules_21_
PubMedSearch : Pisani_2016_Molecules_21_
PubMedID: 26999091

Title : Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases - Farina_2015_J.Med.Chem_58_5561
Author(s) : Farina R , Pisani L , Catto M , Nicolotti O , Gadaleta D , Denora N , Soto-Otero R , Mendez-Alvarez E , Passos CS , Muncipinto G , Altomare CD , Nurisso A , Carrupt PA , Carotti A
Ref : Journal of Medicinal Chemistry , 58 :5561 , 2015
Abstract : Farina_2015_J.Med.Chem_58_5561
ESTHER : Farina_2015_J.Med.Chem_58_5561
PubMedSearch : Farina_2015_J.Med.Chem_58_5561
PubMedID: 26107513

Title : Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors - Pau_2015_ChemMedChem_10_1054
Author(s) : Pau A , Catto M , Pinna G , Frau S , Murineddu G , Asproni B , Curzu MM , Pisani L , Leonetti F , Loza MI , Brea J , Pinna GA , Carotti A
Ref : ChemMedChem , 10 :1054 , 2015
Abstract : Pau_2015_ChemMedChem_10_1054
ESTHER : Pau_2015_ChemMedChem_10_1054
PubMedSearch : Pau_2015_ChemMedChem_10_1054
PubMedID: 25924828

Title : Multitarget Therapeutic Leads for Alzheimer's Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and beta-Amyloid (Abeta) Aggregation - Tonelli_2015_ChemMedChem_10_1040
Author(s) : Tonelli M , Catto M , Tasso B , Novelli F , Canu C , Iusco G , Pisani L , Stradis AD , Denora N , Sparatore A , Boido V , Carotti A , Sparatore F
Ref : ChemMedChem , 10 :1040 , 2015
Abstract : Tonelli_2015_ChemMedChem_10_1040
ESTHER : Tonelli_2015_ChemMedChem_10_1040
PubMedSearch : Tonelli_2015_ChemMedChem_10_1040
PubMedID: 25924599

Title : Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase - Catto_2013_Bioorg.Med.Chem_21_146
Author(s) : Catto M , Pisani L , Leonetti F , Nicolotti O , Pesce P , Stefanachi A , Cellamare S , Carotti A
Ref : Bioorganic & Medicinal Chemistry , 21 :146 , 2013
Abstract : Catto_2013_Bioorg.Med.Chem_21_146
ESTHER : Catto_2013_Bioorg.Med.Chem_21_146
PubMedSearch : Catto_2013_Bioorg.Med.Chem_21_146
PubMedID: 23199476

Title : Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl\/butyryl cholinesterase - Catto_2012_Eur.J.Med.Chem_58C_84
Author(s) : Catto M , Berezin AA , Lo Re D , Loizou G , Demetriades M , De Stradis A , Campagna F , Koutentis PA , Carotti A
Ref : Eur Journal of Medicinal Chemistry , 58C :84 , 2012
Abstract : Catto_2012_Eur.J.Med.Chem_58C_84
ESTHER : Catto_2012_Eur.J.Med.Chem_58C_84
PubMedSearch : Catto_2012_Eur.J.Med.Chem_58C_84
PubMedID: 23108363

Title : Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases - Pisani_2011_Curr.Med.Chem_18_4568
Author(s) : Pisani L , Catto M , Leonetti F , Nicolotti O , Stefanachi A , Campagna F , Carotti A
Ref : Curr Med Chem , 18 :4568 , 2011
Abstract : Pisani_2011_Curr.Med.Chem_18_4568
ESTHER : Pisani_2011_Curr.Med.Chem_18_4568
PubMedSearch : Pisani_2011_Curr.Med.Chem_18_4568
PubMedID: 21864289

Title : Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity - Conejo-Garcia_2011_J.Med.Chem_54_2627
Author(s) : Conejo-Garcia A , Pisani L , Nunez Mdel C , Catto M , Nicolotti O , Leonetti F , Campos JM , Gallo MA , Espinosa A , Carotti A
Ref : Journal of Medicinal Chemistry , 54 :2627 , 2011
Abstract : Conejo-Garcia_2011_J.Med.Chem_54_2627
ESTHER : Conejo-Garcia_2011_J.Med.Chem_54_2627
PubMedSearch : Conejo-Garcia_2011_J.Med.Chem_54_2627
PubMedID: 21417225

Title : Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease - Tasso_2011_Eur.J.Med.Chem_46_2170
Author(s) : Tasso B , Catto M , Nicolotti O , Novelli F , Tonelli M , Giangreco I , Pisani L , Sparatore A , Boido V , Carotti A , Sparatore F
Ref : Eur Journal of Medicinal Chemistry , 46 :2170 , 2011
Abstract : Tasso_2011_Eur.J.Med.Chem_46_2170
ESTHER : Tasso_2011_Eur.J.Med.Chem_46_2170
PubMedSearch : Tasso_2011_Eur.J.Med.Chem_46_2170
PubMedID: 21459491

Title : Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors - Pisani_2010_ChemMedChem_5_1616
Author(s) : Pisani L , Catto M , Giangreco I , Leonetti F , Nicolotti O , Stefanachi A , Cellamare S , Carotti A
Ref : ChemMedChem , 5 :1616 , 2010
Abstract : Pisani_2010_ChemMedChem_5_1616
ESTHER : Pisani_2010_ChemMedChem_5_1616
PubMedSearch : Pisani_2010_ChemMedChem_5_1616
PubMedID: 20677317

Title : Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors - Leonetti_2008_Bioorg.Med.Chem_16_7450
Author(s) : Leonetti F , Catto M , Nicolotti O , Pisani L , Cappa A , Stefanachi A , Carotti A
Ref : Bioorganic & Medicinal Chemistry , 16 :7450 , 2008
Abstract : Leonetti_2008_Bioorg.Med.Chem_16_7450
ESTHER : Leonetti_2008_Bioorg.Med.Chem_16_7450
PubMedSearch : Leonetti_2008_Bioorg.Med.Chem_16_7450
PubMedID: 18585045

Title : Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors - Carotti_2006_Bioorg.Med.Chem_14_7205
Author(s) : Carotti A , de Candia M , Catto M , Borisova TN , Varlamov AV , Mendez-Alvarez E , Soto-Otero R , Voskressensky LG , Altomare CD
Ref : Bioorganic & Medicinal Chemistry , 14 :7205 , 2006
Abstract : Carotti_2006_Bioorg.Med.Chem_14_7205
ESTHER : Carotti_2006_Bioorg.Med.Chem_14_7205
PubMedSearch : Carotti_2006_Bioorg.Med.Chem_14_7205
PubMedID: 16843666

Title : Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase - Bruhlmann_2001_J.Med.Chem_44_3195
Author(s) : Bruhlmann C , Ooms F , Carrupt PA , Testa B , Catto M , Leonetti F , Altomare CD , Carotti A
Ref : Journal of Medicinal Chemistry , 44 :3195 , 2001
Abstract : Bruhlmann_2001_J.Med.Chem_44_3195
ESTHER : Bruhlmann_2001_J.Med.Chem_44_3195
PubMedSearch : Bruhlmann_2001_J.Med.Chem_44_3195
PubMedID: 11543689