| Title : The structure of the monobactam-producing thioesterase domain of SulM forms a unique complex with the upstream carrier protein domain - Patel_2024_J.Biol.Chem_300_107489 |
| Author(s) : Patel KD , Oliver RA , Lichstrahl MS , Li R , Townsend CA , Gulick AM |
| Ref : Journal of Biological Chemistry , 300 :107489 , 2024 |
| Abstract : |
| PubMedSearch : Patel_2024_J.Biol.Chem_300_107489 |
| PubMedID: 38908753 |
| Title : A sticky situation: regulation and function of protein palmitoylation with a spotlight on the axon and axon initial segment - Petropavlovskiy_2021_Neuronal.Signal_5_Ns20210005 |
| Author(s) : Petropavlovskiy AA , Kogut JA , Leekha A , Townsend CA , Sanders SS |
| Ref : Neuronal Signal , 5 :Ns20210005 , 2021 |
| Abstract : |
| PubMedSearch : Petropavlovskiy_2021_Neuronal.Signal_5_Ns20210005 |
| PubMedID: 34659801 |
| Title : Late-Stage Conversion of Diphenylphosphonate to Fluorophosphonate Probes for the Investigation of Serine Hydrolases - d'Andrea_2019_Cell.Chem.Biol_26_878 |
| Author(s) : d'Andrea FB , Townsend CA |
| Ref : Cell Chemical Biology , 26 :878 , 2019 |
| Abstract : |
| PubMedSearch : d'Andrea_2019_Cell.Chem.Biol_26_878 |
| PubMedID: 30982751 |
| Gene_locus related to this paper: 9noca-q5j1q6 |
| Title : Structure of a bound peptide phosphonate reveals the mechanism of nocardicin bifunctional thioesterase epimerase-hydrolase half-reactions - Patel_2019_Nat.Commun_10_3868 |
| Author(s) : Patel KD , d'Andrea FB , Gaudelli NM , Buller AR , Townsend CA , Gulick AM |
| Ref : Nat Commun , 10 :3868 , 2019 |
| Abstract : |
| PubMedSearch : Patel_2019_Nat.Commun_10_3868 |
| PubMedID: 31455765 |
| Gene_locus related to this paper: 9noca-q5j1q6 |
| Title : A dual role for a polyketide synthase in dynemicin enediyne and anthraquinone biosynthesis - Cohen_2018_Nat.Chem_10_231 |
| Author(s) : Cohen DR , Townsend CA |
| Ref : Nat Chem , 10 :231 , 2018 |
| Abstract : |
| PubMedSearch : Cohen_2018_Nat.Chem_10_231 |
| PubMedID: 29359752 |
| Title : The structural organization of substrate loading in iterative polyketide synthases - Herbst_2018_Nat.Chem.Biol_14_474 |
| Author(s) : Herbst DA , Huitt-Roehl CR , Jakob RP , Kravetz JM , Storm PA , Alley JR , Townsend CA , Maier T |
| Ref : Nat Chemical Biology , 14 :474 , 2018 |
| Abstract : |
| PubMedSearch : Herbst_2018_Nat.Chem.Biol_14_474 |
| PubMedID: 29610486 |
| Gene_locus related to this paper: cernc-q6dqw3 |
| Title : Gene cluster conservation provides insight into cercosporin biosynthesis and extends production to the genus Colletotrichum - de Jonge_2018_Proc.Natl.Acad.Sci.U.S.A_115_E5459 |
| Author(s) : de Jonge R , Ebert MK , Huitt-Roehl CR , Pal P , Suttle JC , Spanner RE , Neubauer JD , Jurick WM, 2nd , Stott KA , Secor GA , Thomma B , Van de Peer Y , Townsend CA , Bolton MD |
| Ref : Proc Natl Acad Sci U S A , 115 :E5459 , 2018 |
| Abstract : |
| PubMedSearch : de Jonge_2018_Proc.Natl.Acad.Sci.U.S.A_115_E5459 |
| PubMedID: 29844193 |
| Gene_locus related to this paper: cernc-q6dqw3 , 9pezi-a0a2s6cl14 |
| Title : Monobactam formation in sulfazecin by a nonribosomal peptide synthetase thioesterase - Oliver_2018_Nat.Chem.Biol_14_5 |
| Author(s) : Oliver RA , Li R , Townsend CA |
| Ref : Nat Chemical Biology , 14 :5 , 2018 |
| Abstract : |
| PubMedSearch : Oliver_2018_Nat.Chem.Biol_14_5 |
| PubMedID: 29155429 |
| Title : Identification and Characterization of the Sulfazecin Monobactam Biosynthetic Gene Cluster - Li_2017_Cell.Chem.Biol_24_24 |
| Author(s) : Li R , Oliver RA , Townsend CA |
| Ref : Cell Chemical Biology , 24 :24 , 2017 |
| Abstract : |
| PubMedSearch : Li_2017_Cell.Chem.Biol_24_24 |
| PubMedID: 28017601 |
| Gene_locus related to this paper: 9burk-SulM.TTE |
| Title : Functional and Structural Analysis of Programmed C-Methylation in the Biosynthesis of the Fungal Polyketide Citrinin - Storm_2017_Cell.Chem.Biol_24_316 |
| Author(s) : Storm PA , Herbst DA , Maier T , Townsend CA |
| Ref : Cell Chemical Biology , 24 :316 , 2017 |
| Abstract : |
| PubMedSearch : Storm_2017_Cell.Chem.Biol_24_316 |
| PubMedID: 28238725 |
| Gene_locus related to this paper: monpu-cita |
| Title : Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases - Barajas_2017_Proc.Natl.Acad.Sci.U.S.A_114_E4142 |
| Author(s) : Barajas JF , Shakya G , Moreno G , Rivera H, Jr. , Jackson DR , Topper CL , Vagstad AL , La Clair JJ , Townsend CA , Burkart MD , Tsai SC |
| Ref : Proc Natl Acad Sci U S A , 114 :E4142 , 2017 |
| Abstract : |
| PubMedSearch : Barajas_2017_Proc.Natl.Acad.Sci.U.S.A_114_E4142 |
| PubMedID: 28484029 |
| Title : beta-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis - Gaudelli_2015_Nature_520_383 |
| Author(s) : Gaudelli NM , Long DH , Townsend CA |
| Ref : Nature , 520 :383 , 2015 |
| Abstract : |
| PubMedSearch : Gaudelli_2015_Nature_520_383 |
| PubMedID: 25624104 |
| Title : Epimerization and substrate gating by a TE domain in beta-lactam antibiotic biosynthesis - Gaudelli_2014_Nat.Chem.Biol_10_251 |
| Author(s) : Gaudelli NM , Townsend CA |
| Ref : Nat Chemical Biology , 10 :251 , 2014 |
| Abstract : |
| PubMedSearch : Gaudelli_2014_Nat.Chem.Biol_10_251 |
| PubMedID: 24531841 |
| Gene_locus related to this paper: 9noca-q5j1q6 |
| Title : Characterization of a fungal thioesterase having Claisen cyclase and deacetylase activities in melanin biosynthesis - Vagstad_2012_Chem.Biol_19_1525 |
| Author(s) : Vagstad AL , Hill EA , Labonte JW , Townsend CA |
| Ref : Chemical Biology , 19 :1525 , 2012 |
| Abstract : |
| PubMedSearch : Vagstad_2012_Chem.Biol_19_1525 |
| PubMedID: 23261597 |
| Gene_locus related to this paper: glola-PKS1 |
| Title : Environmental control of the calicheamicin polyketide synthase leads to detection of a programmed octaketide and a proposal for enediyne biosynthesis - Belecki_2012_Angew.Chem.Int.Ed.Engl_51_11316 |
| Author(s) : Belecki K , Townsend CA |
| Ref : Angew Chem Int Ed Engl , 51 :11316 , 2012 |
| Abstract : |
| PubMedSearch : Belecki_2012_Angew.Chem.Int.Ed.Engl_51_11316 |
| PubMedID: 23042574 |
| Title : Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis - Korman_2010_Proc.Natl.Acad.Sci.U.S.A_107_6246 |
| Author(s) : Korman TP , Crawford JM , Labonte JW , Newman AG , Wong J , Townsend CA , Tsai SC |
| Ref : Proc Natl Acad Sci U S A , 107 :6246 , 2010 |
| Abstract : |
| PubMedSearch : Korman_2010_Proc.Natl.Acad.Sci.U.S.A_107_6246 |
| PubMedID: 20332208 |
| Gene_locus related to this paper: aspor-PKSL1 |
| Title : Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization - Crawford_2009_Nature_461_1139 |
| Author(s) : Crawford JM , Korman TP , Labonte JW , Vagstad AL , Hill EA , Kamari-Bidkorpeh O , Tsai SC , Townsend CA |
| Ref : Nature , 461 :1139 , 2009 |
| Abstract : |
| PubMedSearch : Crawford_2009_Nature_461_1139 |
| PubMedID: 19847268 |
| Title : Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures - Belecki_2009_J.Am.Chem.Soc_131_12564 |
| Author(s) : Belecki K , Crawford JM , Townsend CA |
| Ref : Journal of the American Chemical Society , 131 :12564 , 2009 |
| Abstract : |
| PubMedSearch : Belecki_2009_J.Am.Chem.Soc_131_12564 |
| PubMedID: 19689130 |
| Title : Starter unit specificity directs genome mining of polyketide synthase pathways in fungi - Crawford_2008_Bioorg.Chem_36_16 |
| Author(s) : Crawford JM , Vagstad AL , Ehrlich KC , Townsend CA |
| Ref : Bioorg Chem , 36 :16 , 2008 |
| Abstract : |
| PubMedSearch : Crawford_2008_Bioorg.Chem_36_16 |
| PubMedID: 18215412 |
| Title : Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases - |
| Author(s) : Crawford JM , Vagstad AL , Ehrlich KC , Udwary DW , Townsend CA |
| Ref : Chembiochem , 9 :1559 , 2008 |
| PubMedID: 18551496 |
| Title : Deconstruction of iterative multidomain polyketide synthase function - Crawford_2008_Science_320_243 |
| Author(s) : Crawford JM , Thomas PM , Scheerer JR , Vagstad AL , Kelleher NL , Townsend CA |
| Ref : Science , 320 :243 , 2008 |
| Abstract : |
| PubMedSearch : Crawford_2008_Science_320_243 |
| PubMedID: 18403714 |
| Gene_locus related to this paper: aspor-PKSL1 , asppa-q6ueg5 |
| Title : The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A - Gunsior_2004_Chem.Biol_11_927 |
| Author(s) : Gunsior M , Breazeale SD , Lind AJ , Ravel J , Janc JW , Townsend CA |
| Ref : Chemical Biology , 11 :927 , 2004 |
| Abstract : |
| PubMedSearch : Gunsior_2004_Chem.Biol_11_927 |
| PubMedID: 15271351 |
| Gene_locus related to this paper: 9noca-q5j1q6 |
| Title : Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of aflatoxin B(1) - Watanabe_2002_Chem.Biol_9_981 |
| Author(s) : Watanabe CM , Townsend CA |
| Ref : Chemical Biology , 9 :981 , 2002 |
| Abstract : |
| PubMedSearch : Watanabe_2002_Chem.Biol_9_981 |
| PubMedID: 12323372 |
| Title : Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors - Loftus_2000_Science_288_2379 |
| Author(s) : Loftus TM , Jaworsky DE , Frehywot GL , Townsend CA , Ronnett GV , Lane MD , Kuhajda FP |
| Ref : Science , 288 :2379 , 2000 |
| Abstract : |
| PubMedSearch : Loftus_2000_Science_288_2379 |
| PubMedID: 10875926 |
| Title : Heterologous expression, isolation, and characterization of versicolorin B synthase from Aspergillus parasiticus. A key enzyme in the aflatoxin B1 biosynthetic pathway - Silva_1997_J.Biol.Chem_272_804 |
| Author(s) : Silva JC , Townsend CA |
| Ref : Journal of Biological Chemistry , 272 :804 , 1997 |
| Abstract : |
| PubMedSearch : Silva_1997_J.Biol.Chem_272_804 |
| PubMedID: 8995367 |
| Title : Demonstration of the catalytic roles and evidence for the physical association of type I fatty acid synthases and a polyketide synthase in the biosynthesis of aflatoxin B1 - Watanabe_1996_Chem.Biol_3_463 |
| Author(s) : Watanabe CM , Wilson D , Linz JE , Townsend CA |
| Ref : Chemical Biology , 3 :463 , 1996 |
| Abstract : |
| PubMedSearch : Watanabe_1996_Chem.Biol_3_463 |
| PubMedID: 8807876 |