Full name : van Helden Herman PM
First name : Herman PM
Mail : NO Defence, Security and Safety, BU Biological and Chemical Protection, Rijswijk
Zip Code :
City :
Country : The Netherlands
Email : herman.vanhelden@tno.nl
Phone :
Fax :
Website :
Directory :
Comment
| Title : Timing of decontamination and treatment in case of percutaneous VX poisoning: A mini review - Joosen_2013_Chem.Biol.Interact_203_149 |
| Author(s) : Joosen MJ , van der Schans MJ , Kuijpers WC , van Helden HP , Noort D |
| Ref : Chemico-Biological Interactions , 203 :149 , 2013 |
| Abstract : |
| PubMedSearch : Joosen_2013_Chem.Biol.Interact_203_149 |
| PubMedID: 23085122 |
| Title : Non-enzymatic pretreatment of nerve agent (soman) poisoning: a brief state-of-the-art review - van Helden_2011_Toxicol.Lett_206_35 |
| Author(s) : van Helden HP , Joosen MJ , Philippens IH |
| Ref : Toxicol Lett , 206 :35 , 2011 |
| Abstract : |
| PubMedSearch : van Helden_2011_Toxicol.Lett_206_35 |
| PubMedID: 21554933 |
| Title : Treatment efficacy in a soman-poisoned guinea pig model: added value of physostigmine? - Joosen_2011_Arch.Toxicol_85_227 |
| Author(s) : Joosen MJ , Smit AB , van Helden HP |
| Ref : Archives of Toxicology , 85 :227 , 2011 |
| Abstract : |
| PubMedSearch : Joosen_2011_Arch.Toxicol_85_227 |
| PubMedID: 20842348 |
| Title : Increasing oxime efficacy by blood-brain barrier modulation - Joosen_2011_Toxicol.Lett_206_67 |
| Author(s) : Joosen MJ , van der Schans MJ , van Dijk CG , Kuijpers WC , Wortelboer HM , van Helden HP |
| Ref : Toxicol Lett , 206 :67 , 2011 |
| Abstract : |
| PubMedSearch : Joosen_2011_Toxicol.Lett_206_67 |
| PubMedID: 21600273 |
| Title : Percutaneous exposure to the nerve agent VX: Efficacy of combined atropine, obidoxime and diazepam treatment - Joosen_2010_Chem.Biol.Interact_188_255 |
| Author(s) : Joosen MJ , van der Schans MJ , van Helden HP |
| Ref : Chemico-Biological Interactions , 188 :255 , 2010 |
| Abstract : |
| PubMedSearch : Joosen_2010_Chem.Biol.Interact_188_255 |
| PubMedID: 20599844 |
| Title : Long-term cognitive deficits accompanied by reduced neurogenesis after soman poisoning - Joosen_2009_Neurotoxicol_30_72 |
| Author(s) : Joosen MJ , Jousma E , van den Boom TM , Kuijpers WC , Smit AB , Lucassen PJ , van Helden HP |
| Ref : Neurotoxicology , 30 :72 , 2009 |
| Abstract : |
| PubMedSearch : Joosen_2009_Neurotoxicol_30_72 |
| PubMedID: 19100287 |
| Title : Percutaneous exposure to VX: clinical signs, effects on brain acetylcholine levels and EEG - Joosen_2008_Neurochem.Res_33_308 |
| Author(s) : Joosen MJ , van der Schans MJ , van Helden HP |
| Ref : Neurochem Res , 33 :308 , 2008 |
| Abstract : |
| PubMedSearch : Joosen_2008_Neurochem.Res_33_308 |
| PubMedID: 17940880 |
| Title : Correlations between acetylcholinesterase inhibition, acetylcholine levels and EEG changes during perfusion with neostigmine and N6-cyclopentyladenosine in rat brain - Joosen_2007_Eur.J.Pharmacol_555_122 |
| Author(s) : Joosen MJ , van Helden HP |
| Ref : European Journal of Pharmacology , 555 :122 , 2007 |
| Abstract : |
| PubMedSearch : Joosen_2007_Eur.J.Pharmacol_555_122 |
| PubMedID: 17113068 |
| Title : Low-level exposure of guinea pigs and marmosets to sarin vapour in air: lowest-observable-adverse-effect level (LOAEL) for miosis - van Helden_2004_J.Appl.Toxicol_24_59 |
| Author(s) : van Helden HP , Trap HC , Kuijpers WC , Oostdijk JP , Benschop HP , Langenberg JP |
| Ref : J Appl Toxicol , 24 :59 , 2004 |
| Abstract : |
| PubMedSearch : van Helden_2004_J.Appl.Toxicol_24_59 |
| PubMedID: 14745848 |
| Title : Cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) decisive for its therapeutic efficacy in sarin poisoning - Joosen_2004_Arch.Toxicol_78_34 |
| Author(s) : Joosen MJ , Bueters TJ , van Helden HP |
| Ref : Archives of Toxicology , 78 :34 , 2004 |
| Abstract : |
| PubMedSearch : Joosen_2004_Arch.Toxicol_78_34 |
| PubMedID: 14508639 |
| Title : Therapeutic efficacy in organophosphate poisoning by inhibiting central release of acetylcholine. - |
| Author(s) : Bueters TJ , Groen B , Harrison PK , Tattersall JE , Ijzerman AP , Danhof M , van Helden HP |
| Ref : Cholinergic Mechanisms, CRC Press :255 , 2004 |
| PubMedID: |
| Title : Protection of rats against perfluoroisobutene (PFIB)-induced pulmonary edema by curosurf and N-acetylcysteine - van Helden_2004_Inhal.Toxicol_16_549 |
| Author(s) : van Helden HP , van de Meent D , Oostdijk JP , Joosen MJ , van Esch JH , Hammer AH , Diemel RV |
| Ref : Inhal Toxicol , 16 :549 , 2004 |
| Abstract : |
| PubMedSearch : van Helden_2004_Inhal.Toxicol_16_549 |
| PubMedID: 15204746 |
| Title : Adenosine A1 receptor agonist N6-cyclopentyladenosine affects the inactivation of acetylcholinesterase in blood and brain by sarin - Bueters_2003_J.Pharmacol.Exp.Ther_304_1307 |
| Author(s) : Bueters TJ , Joosen MJ , van Helden HP , Ijzerman AP , Danhof M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 304 :1307 , 2003 |
| Abstract : |
| PubMedSearch : Bueters_2003_J.Pharmacol.Exp.Ther_304_1307 |
| PubMedID: 12604711 |
| Title : Partial adenosine A(1) receptor agonists inhibit sarin-induced epileptiform activity in the hippocampal slice - Harrison_2003_Eur.J.Pharmacol_471_97 |
| Author(s) : Harrison PK , Bueters TJ , Ijzerman AP , van Helden HP , Tattersall JE |
| Ref : European Journal of Pharmacology , 471 :97 , 2003 |
| Abstract : |
| PubMedSearch : Harrison_2003_Eur.J.Pharmacol_471_97 |
| PubMedID: 12818696 |
| Title : Long-term, low-level exposure of guinea pigs and marmosets to sarin vapor in air: lowest observable effect level - Van Helden_2003_Toxicol.Appl.Pharmacol_189_170 |
| Author(s) : van Helden HP , Trap HC , Oostdijk JP , Kuijpers WC , Langenberg JP , Benschop HP |
| Ref : Toxicol Appl Pharmacol , 189 :170 , 2003 |
| Abstract : |
| PubMedSearch : Van Helden_2003_Toxicol.Appl.Pharmacol_189_170 |
| PubMedID: 12791302 |
| Title : Therapeutic efficacy of the adenosine A(1) receptor agonist N(6)- cyclopentyladenosine (CPA) against organophosphate intoxication - Bueters_2002_Arch.Toxicol_76_650 |
| Author(s) : Bueters TJ , Groen B , Danhof M , AP IJ , van Helden HP |
| Ref : Archives of Toxicology , 76 :650 , 2002 |
| Abstract : |
| PubMedSearch : Bueters_2002_Arch.Toxicol_76_650 |
| PubMedID: 12415428 |
| Title : Inhalation toxicokinetics of soman stereoisomers in the atropinized guinea pig with nose-only exposure to soman vapor - Langenberg_1998_Toxicol.Appl.Pharmacol_151_79 |
| Author(s) : Langenberg JP , Spruit HE , van der Wiel HJ , Trap HC , Helmich RB , Bergers WW , van Helden HP , Benschop HP |
| Ref : Toxicol Appl Pharmacol , 151 :79 , 1998 |
| Abstract : |
| PubMedSearch : Langenberg_1998_Toxicol.Appl.Pharmacol_151_79 |
| PubMedID: 9705889 |
| Title : Effects of low doses of cholinesterase inhibitors on behavioral performance of robot-tested marmosets - Wolthuis_1995_Pharmacol.Biochem.Behav_51_443 |
| Author(s) : Wolthuis OL , Groen B , Busker RW , van Helden HP |
| Ref : Pharmacology, Biochemistry & Behavior , 51 :443 , 1995 |
| Abstract : |
| PubMedSearch : Wolthuis_1995_Pharmacol.Biochem.Behav_51_443 |
| PubMedID: 7667367 |
| Title : Comparison of the therapeutic effects and pharmacokinetics of HI-6, HLo-7, HGG-12, HGG-42 and obidoxime following non-reactivatable acetylcholinesterase inhibition in rats - van Helden_1994_Arch.Toxicol_68_224 |
| Author(s) : van Helden HP , van der Wiel HJ , Zijlstra JJ , Melchers BP , Busker RW |
| Ref : Archives of Toxicology , 68 :224 , 1994 |
| Abstract : |
| PubMedSearch : van Helden_1994_Arch.Toxicol_68_224 |
| PubMedID: 8067894 |
| Title : Non-reactivating effects of HI-6 on hippocampal neurotransmission - Melchers_1994_Arch.Toxicol_69_118 |
| Author(s) : Melchers BP , van der Laaken AL , Busker RW , Bruijnzeel PL , van Helden HP |
| Ref : Archives of Toxicology , 69 :118 , 1994 |
| Abstract : |
| PubMedSearch : Melchers_1994_Arch.Toxicol_69_118 |
| PubMedID: 7717860 |
| Title : The functional role of molecular forms of acetylcholinesterase in neuromuscular transmission - Busker_1994_Neurochem.Res_19_713 |
| Author(s) : Busker RW , Zijlstra JJ , van der Wiel HJ , van Helden HP |
| Ref : Neurochemical Research , 19 :713 , 1994 |
| Abstract : |
| PubMedSearch : Busker_1994_Neurochem.Res_19_713 |
| PubMedID: 8065529 |
| Title : Search for a therapy against soman-intoxication. - Wolthuis_1994_Neurosci.Biobehav.Rev_18_469 |
| Author(s) : Wolthuis OL , van Helden HP , Melchers BP , Busker RW , de Groot DM |
| Ref : Neurosci Biobehav Rev , 18 :469 , 1994 |
| Abstract : |
| PubMedSearch : Wolthuis_1994_Neurosci.Biobehav.Rev_18_469 |
| PubMedID: 7708361 |
| Title : Therapeutic efficacy of HI-6 in soman-poisoned marmoset monkeys - van Helden_1992_Toxicol.Appl.Pharmacol_115_50 |
| Author(s) : van Helden HP , van der Wiel HJ , de Lange J , Busker RW , Melchers BP , Wolthuis OL |
| Ref : Toxicol Appl Pharmacol , 115 :50 , 1992 |
| Abstract : |
| PubMedSearch : van Helden_1992_Toxicol.Appl.Pharmacol_115_50 |
| PubMedID: 1631893 |
| Title : Organophosphate poisoning: a method to test therapeutic effects of oximes other than acetylcholinesterase reactivation in the rat - Busker_1991_Toxicology_69_331 |
| Author(s) : Busker RW , Zijlstra JJ , van der Wiel HJ , Melchers BP , van Helden HP |
| Ref : Toxicology , 69 :331 , 1991 |
| Abstract : |
| PubMedSearch : Busker_1991_Toxicology_69_331 |
| PubMedID: 1658986 |
| Title : New simulators in the prophylaxis against soman poisoning: structural specificity for the depot site(s) - Van Helden_1984_J.Pharm.Pharmacol_36_305 |
| Author(s) : van Helden HP , Benschop HP , Wolthuis OL |
| Ref : J Pharm Pharmacol , 36 :305 , 1984 |
| Abstract : |
| PubMedSearch : Van Helden_1984_J.Pharm.Pharmacol_36_305 |
| PubMedID: 6145765 |
| Title : On the existence of a Soman depot - |
| Author(s) : van Helden HP , Berends F , Wolthuis OL , Benschop HP |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :375 , 1984 |
| PubMedID: |
| Title : Therapy of organophosphate poisoning: the marmoset as a model for man - van Helden_1983_Br.J.Pharmacol_78_579 |
| Author(s) : van Helden HP , van der Wiel HJ , Wolthuis OL |
| Ref : British Journal of Pharmacology , 78 :579 , 1983 |
| Abstract : |
| PubMedSearch : van Helden_1983_Br.J.Pharmacol_78_579 |
| PubMedID: 6301602 |