Full name : Benschop Hendrik P
First name : Hendrik P
Mail : TNO Prins Maurits Laboratory PostBox 45 2280 AA Rijswijk
Zip Code :
City :
Country : The Netherlands
Email :
Phone :
Fax :
Website : \/\/www.sciencedirect.com\/science\/article\/pii\/S0009279713001300
Directory :
Comment
Dr. Henk P. Benschop was born on September 19, 1939 and passed away on April 16 2013. Henk P. Benschop was a Senior Research Fellow at TNO (Dutch Organization for Applied Scientific Research). He Developed highly sensitive methods for (chiral) analysis of chemical nerve agents. A paper by Daan Noort retraces his achievements obituary paper.
| Title : New tools in diagnosis and biomonitoring of intoxications with organophosphorothioates: Case studies with chlorpyrifos and diazinon - van der Schans_2013_Chem.Biol.Interact_203_96 |
| Author(s) : van der Schans MJ , Hulst AG , van der Riet-van Oeveren D , Noort D , Benschop HP , Dishovsky C |
| Ref : Chemico-Biological Interactions , 203 :96 , 2013 |
| Abstract : |
| PubMedSearch : van der Schans_2013_Chem.Biol.Interact_203_96 |
| PubMedID: 23123253 |
| Title : Biochemical and behavioral effects of soman vapors in low concentrations - Bajgar_2004_Inhal.Toxicol_16_497 |
| Author(s) : Bajgar J , Sevelova L , Krejcova G , Fusek J , Vachek J , Kassa J , Herink J , De Jong LP , Benschop HP |
| Ref : Inhal Toxicol , 16 :497 , 2004 |
| Abstract : |
| PubMedSearch : Bajgar_2004_Inhal.Toxicol_16_497 |
| PubMedID: 15204741 |
| Title : Retrospective detection of exposure to nerve agents: analysis of phosphofluoridates originating from fluoride-induced reactivation of phosphylated BuChE - van der Schans_2004_Arch.Toxicol_78_508 |
| Author(s) : van der Schans MJ , Polhuijs M , van Dijk C , Degenhardt CE , Pleijsier K , Langenberg JP , Benschop HP |
| Ref : Archives of Toxicology , 78 :508 , 2004 |
| Abstract : |
| PubMedSearch : van der Schans_2004_Arch.Toxicol_78_508 |
| PubMedID: 15170525 |
| Title : Low-level exposure of guinea pigs and marmosets to sarin vapour in air: lowest-observable-adverse-effect level (LOAEL) for miosis - van Helden_2004_J.Appl.Toxicol_24_59 |
| Author(s) : van Helden HP , Trap HC , Kuijpers WC , Oostdijk JP , Benschop HP , Langenberg JP |
| Ref : J Appl Toxicol , 24 :59 , 2004 |
| Abstract : |
| PubMedSearch : van Helden_2004_J.Appl.Toxicol_24_59 |
| PubMedID: 14745848 |
| Title : Toxicokinetics of the nerve agent (+\/-)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration - van der Schans_2003_Toxicol.Appl.Pharmacol_191_48 |
| Author(s) : van der Schans MJ , Lander BJ , van der Wiel H , Langenberg JP , Benschop HP |
| Ref : Toxicol Appl Pharmacol , 191 :48 , 2003 |
| Abstract : |
| PubMedSearch : van der Schans_2003_Toxicol.Appl.Pharmacol_191_48 |
| PubMedID: 12915103 |
| Title : Long-term, low-level exposure of guinea pigs and marmosets to sarin vapor in air: lowest observable effect level - Van Helden_2003_Toxicol.Appl.Pharmacol_189_170 |
| Author(s) : van Helden HP , Trap HC , Oostdijk JP , Kuijpers WC , Langenberg JP , Benschop HP |
| Ref : Toxicol Appl Pharmacol , 189 :170 , 2003 |
| Abstract : |
| PubMedSearch : Van Helden_2003_Toxicol.Appl.Pharmacol_189_170 |
| PubMedID: 12791302 |
| Title : Biomonitoring of exposure to chemical warfare agents: a review - Noort_2002_Toxicol.Appl.Pharmacol_184_116 |
| Author(s) : Noort D , Benschop HP , Black RM |
| Ref : Toxicol Appl Pharmacol , 184 :116 , 2002 |
| Abstract : |
| PubMedSearch : Noort_2002_Toxicol.Appl.Pharmacol_184_116 |
| PubMedID: 12408956 |
| Title : Retrospective detection of exposure to organophosphorus anti-cholinesterases: mass spectrometric analysis of phosphylated human butyrylcholinesterase - Fidder_2002_Chem.Res.Toxicol_15_582 |
| Author(s) : Fidder A , Hulst AG , Noort D , de Ruiter R , van der Schans MJ , Benschop HP , Langenberg JP |
| Ref : Chemical Research in Toxicology , 15 :582 , 2002 |
| Abstract : |
| PubMedSearch : Fidder_2002_Chem.Res.Toxicol_15_582 |
| PubMedID: 11952345 |
| Title : Exploring the active center of human acetylcholinesterase with stereomers of an organophosphorus inhibitor with two chiral centers - Ordentlich_1999_Biochemistry_38_3055 |
| Author(s) : Ordentlich A , Barak D , Kronman C , Benschop HP , De Jong LP , Ariel N , Barak R , Segall Y , Velan B , Shafferman A |
| Ref : Biochemistry , 38 :3055 , 1999 |
| Abstract : |
| PubMedSearch : Ordentlich_1999_Biochemistry_38_3055 |
| PubMedID: 10074358 |
| Title : Quantitative analysis of O-isopropyl methylphosphonic acid in serum samples of Japanese citizens allegedly exposed to sarin: estimation of internal dosage - Noort_1998_Arch.Toxicol_72_671 |
| Author(s) : Noort D , Hulst AG , Platenburg DH , Polhuijs M , Benschop HP |
| Ref : Archives of Toxicology , 72 :671 , 1998 |
| Abstract : |
| PubMedSearch : Noort_1998_Arch.Toxicol_72_671 |
| PubMedID: 9851684 |
| Title : Inhalation toxicokinetics of soman stereoisomers in the atropinized guinea pig with nose-only exposure to soman vapor - Langenberg_1998_Toxicol.Appl.Pharmacol_151_79 |
| Author(s) : Langenberg JP , Spruit HE , van der Wiel HJ , Trap HC , Helmich RB , Bergers WW , van Helden HP , Benschop HP |
| Ref : Toxicol Appl Pharmacol , 151 :79 , 1998 |
| Abstract : |
| PubMedSearch : Langenberg_1998_Toxicol.Appl.Pharmacol_151_79 |
| PubMedID: 9705889 |
| Title : The Aromatic Moiety at Position-86 of HuAChE Accelerate the Aging of Phosphonyl-AChE Conjugates through Cation- Interactions - |
| Author(s) : Barak D , Ordentlich A , Stein D , Segall Y , Velan B , Benschop HP , De Jong LP , Shafferman A |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :246 , 1998 |
| PubMedID: |
| Title : ESMS as a Unique Tool for the Molecular Monitoring of Reactions between HuAChE and Various OP-Agents - |
| Author(s) : Ordentlich A , Barak R , Barak D , Fischer M , Benschop HP , De Jong LP , Segall Y , Velan B , Shafferman A |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :249 , 1998 |
| PubMedID: |
| Title : Retrospective Detection of Exposure to Nerve Agents in the Rhesus Monkey and in Man - |
| Author(s) : Polhuijs M , Langenberg JP , Noort D , Hulst AG , Benschop HP |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :261 , 1998 |
| PubMedID: |
| Title : Direct determination of the chemical composition of acetylcholinesterase phosphonylation products utilizing electrospray- ionization mass spectrometry - Barak_1997_FEBS.Lett_407_347 |
| Author(s) : Barak R , Ordentlich A , Barak D , Fischer M , Benschop HP , De Jong LP , Segall Y , Velan B , Shafferman A |
| Ref : FEBS Letters , 407 :347 , 1997 |
| Abstract : |
| PubMedSearch : Barak_1997_FEBS.Lett_407_347 |
| PubMedID: 9175882 |
| Title : New method for retrospective detection of exposure to organophosphorus anticholinesterases: application to alleged sarin victims of Japanese terrorists - Polhuijs_1997_Toxicol.Appl.Pharmacol_146_156 |
| Author(s) : Polhuijs M , Langenberg JP , Benschop HP |
| Ref : Toxicol Appl Pharmacol , 146 :156 , 1997 |
| Abstract : |
| PubMedSearch : Polhuijs_1997_Toxicol.Appl.Pharmacol_146_156 |
| PubMedID: 9299607 |
| Title : Protection of guinea pigs against soman poisoning by pretreatment with p-nitrophenyl phosphoramidates - Langenberg_1996_Toxicol.Appl.Pharmacol_140_444 |
| Author(s) : Langenberg JP , De Jong LP , Benschop HP |
| Ref : Toxicology & Applied Pharmacology , 140 :444 , 1996 |
| Abstract : |
| PubMedSearch : Langenberg_1996_Toxicol.Appl.Pharmacol_140_444 |
| PubMedID: 8887462 |
| Title : Inhalation Toxicokinetics of C(+\/-)P(+\/-)-Soman and (+\/-)-Sarin in the Guinea Pig - |
| Author(s) : Benschop HP , De Jong LP , Langenberg JP |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :361 , 1995 |
| PubMedID: |
| Title : Toxicokinetics of soman stereoisomers after subcutaneous administration to atropinized guinea pigs - Due_1994_Arch.Toxicol_68_60 |
| Author(s) : Due AH , Trap HC , Langenberg JP , Benschop HP |
| Ref : Archives of Toxicology , 68 :60 , 1994 |
| Abstract : |
| PubMedSearch : Due_1994_Arch.Toxicol_68_60 |
| PubMedID: 8166606 |
| Title : Effect of pretreatment with CBDP on the toxicokinetics of soman stereoisomers in rats and guinea pigs - Due_1993_Arch.Toxicol_67_706 |
| Author(s) : Due AH , Trap HC , van der Wiel HJ , Benschop HP |
| Ref : Archives of Toxicology , 67 :706 , 1993 |
| Abstract : |
| PubMedSearch : Due_1993_Arch.Toxicol_67_706 |
| PubMedID: 8135661 |
| Title : Interactions of Esterases with Soman and Other Chiral Anticholinesterase Organophosphates - |
| Author(s) : De Jong LP , Benschop HP |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :240 , 1991 |
| PubMedID: |
| Title : Stereoisomers of soman (pinacolyl methylphosphonofluoridate): inhibition of serum carboxylic ester hydrolase and potentiation of their toxicity by CBDP (2-(2-methylphenoxy)-4H-1,3,2-benzodioxaphosphorin-2-oxide) in mice - Clement_1987_Toxicol.Appl.Pharmacol_89_141 |
| Author(s) : Clement JG , Benschop HP , DeJong LP , Wolthuis OL |
| Ref : Toxicol Appl Pharmacol , 89 :141 , 1987 |
| Abstract : |
| PubMedSearch : Clement_1987_Toxicol.Appl.Pharmacol_89_141 |
| PubMedID: 3590185 |
| Title : Structural and stereochemical specificity of mouse monoclonal antibodies to the organophosphorous cholinesterase inhibitor soman - Brimfield_1985_Mol.Pharmacol_28_32 |
| Author(s) : Brimfield AA , Hunter KW, Jr. , Lenz DE , Benschop HP , van Dijk C , De Jong LP |
| Ref : Molecular Pharmacology , 28 :32 , 1985 |
| Abstract : |
| PubMedSearch : Brimfield_1985_Mol.Pharmacol_28_32 |
| PubMedID: 4021995 |
| Title : On the existence of a Soman depot - |
| Author(s) : van Helden HP , Berends F , Wolthuis OL , Benschop HP |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :375 , 1984 |
| PubMedID: |
| Title : New simulators in the prophylaxis against soman poisoning: structural specificity for the depot site(s) - Van Helden_1984_J.Pharm.Pharmacol_36_305 |
| Author(s) : van Helden HP , Benschop HP , Wolthuis OL |
| Ref : J Pharm Pharmacol , 36 :305 , 1984 |
| Abstract : |
| PubMedSearch : Van Helden_1984_J.Pharm.Pharmacol_36_305 |
| PubMedID: 6145765 |
| Title : Isolation, anticholinesterase properties, and acute toxicity in mice of the four stereoisomers of the nerve agent soman - Benschop_1984_Toxicol.Appl.Pharmacol_72_61 |
| Author(s) : Benschop HP , Konings CA , Van Genderen J , De Jong LP |
| Ref : Toxicology & Applied Pharmacology , 72 :61 , 1984 |
| Abstract : |
| PubMedSearch : Benschop_1984_Toxicol.Appl.Pharmacol_72_61 |
| PubMedID: 6710485 |
| Title : Stereochemical analysis of the nerve agents soman, sarin, tabun, and VX by proton NMR-spectroscopy with optically active shift reagents - |
| Author(s) : Van den Berg GR , Beck HC , Benschop HP |
| Ref : Bulletin of Environmental Contamination & Toxicology , 33 :505 , 1984 |
| PubMedID: 6498353 |
| Title : Poster 73. Interaction of the resolved isomers of soman with chicken brain acetylcholinesterase and neuropathy target esterase - |
| Author(s) : Johnson MK , Read DJ , Benschop HP |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984 |
| PubMedID: |
| Title : Persistence of the anti-cholinesterase soman in rats\; antagonism with a non-toxic simulator of this organophosphate - Wolthuis_1981_Eur.J.Pharmacol_69_379 |
| Author(s) : Wolthuis OL , Benschop HP , Berends F |
| Ref : European Journal of Pharmacology , 69 :379 , 1981 |
| Abstract : |
| PubMedSearch : Wolthuis_1981_Eur.J.Pharmacol_69_379 |
| PubMedID: 7215436 |
| Title : Antidotes or organophosphate poisoning. 2. Thiadiazole-5-carboxaldoximes - |
| Author(s) : Benschop HP , Van den Berg GR , van Hooidonk C , De Jong LP , Kientz CE , Berends F , Kepner LA , Meeter E , Visser RP |
| Ref : Archives of Toxicology Suppl , 4 :475 , 1980 |
| PubMedID: 533877 |
| Title : On the mechanism of aging of phosphorylated cholinesterases - |
| Author(s) : Benschop HP , Keijer JH |
| Ref : Biochimica & Biophysica Acta , 128 :586 , 1966 |
| PubMedID: |