Sivilotti LG

General

Full name : Sivilotti Lucia G

First name : Lucia

Mail : Department of Neuroscience, Physiology and Pharmacology, Medical Sciences Building, University College London, Gower St, London WC1E 6BT

Zip Code :

City :

Country : United Kingdom

Email : l.sivilotti@ucl.ac.uk

Phone :

Fax :

Website :

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References (41)

Title : High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor - Groot-Kormelink_2016_PLoS.One_11_e0163129
Author(s) : Groot-Kormelink PJ , Ferrand S , Kelley N , Bill A , Freuler F , Imbert PE , Marelli A , Gerwin N , Sivilotti LG , Miraglia L , Orth AP , Oakeley EJ , Schopfer U , Siehler S
Ref : PLoS ONE , 11 :e0163129 , 2016
Abstract : Groot-Kormelink_2016_PLoS.One_11_e0163129
ESTHER : Groot-Kormelink_2016_PLoS.One_11_e0163129
PubMedSearch : Groot-Kormelink_2016_PLoS.One_11_e0163129
PubMedID: 27649498

Title : Bayesian Statistical Inference in Ion-Channel Models with Exact Missed Event Correction - Epstein_2016_Biophys.J_111_333
Author(s) : Epstein M , Calderhead B , Girolami MA , Sivilotti LG
Ref : Biophysical Journal , 111 :333 , 2016
Abstract : Epstein_2016_Biophys.J_111_333
ESTHER : Epstein_2016_Biophys.J_111_333
PubMedSearch : Epstein_2016_Biophys.J_111_333
PubMedID: 27463136

Title : The kinetic properties of the alpha3 rat glycine receptor make it suitable for mediating fast synaptic inhibition - Marabelli_2013_J.Physiol_591_3289
Author(s) : Marabelli A , Moroni M , Lape R , Sivilotti LG
Ref : Journal of Physiology , 591 :3289 , 2013
Abstract : Marabelli_2013_J.Physiol_591_3289
ESTHER : Marabelli_2013_J.Physiol_591_3289
PubMedSearch : Marabelli_2013_J.Physiol_591_3289
PubMedID: 23613537

Title : Inhibition of the prokaryotic pentameric ligand-gated ion channel ELIC by divalent cations - Zimmermann_2012_PLoS.Biol_10_e1001429
Author(s) : Zimmermann I , Marabelli A , Bertozzi C , Sivilotti LG , Dutzler R
Ref : PLoS Biol , 10 :e1001429 , 2012
Abstract : Zimmermann_2012_PLoS.Biol_10_e1001429
ESTHER : Zimmermann_2012_PLoS.Biol_10_e1001429
PubMedSearch : Zimmermann_2012_PLoS.Biol_10_e1001429
PubMedID: 23185134

Title : The alpha1K276E startle disease mutation reveals multiple intermediate states in the gating of glycine receptors - Lape_2012_J.Neurosci_32_1336
Author(s) : Lape R , Plested AJ , Moroni M , Colquhoun D , Sivilotti LG
Ref : Journal of Neuroscience , 32 :1336 , 2012
Abstract : Lape_2012_J.Neurosci_32_1336
ESTHER : Lape_2012_J.Neurosci_32_1336
PubMedSearch : Lape_2012_J.Neurosci_32_1336
PubMedID: 22279218

Title : The long activations of alpha2 glycine channels can be described by a mechanism with reaction intermediates (flip) - Krashia_2011_J.Gen.Physiol_137_197
Author(s) : Krashia P , Lape R , Lodesani F , Colquhoun D , Sivilotti LG
Ref : Journal of General Physiology , 137 :197 , 2011
Abstract : Krashia_2011_J.Gen.Physiol_137_197
ESTHER : Krashia_2011_J.Gen.Physiol_137_197
PubMedSearch : Krashia_2011_J.Gen.Physiol_137_197
PubMedID: 21282399

Title : Chloride ions in the pore of glycine and GABA channels shape the time course and voltage dependence of agonist currents - Moroni_2011_J.Neurosci_31_14095
Author(s) : Moroni M , Biro I , Giugliano M , Vijayan R , Biggin PC , Beato M , Sivilotti LG
Ref : Journal of Neuroscience , 31 :14095 , 2011
Abstract : Moroni_2011_J.Neurosci_31_14095
ESTHER : Moroni_2011_J.Neurosci_31_14095
PubMedSearch : Moroni_2011_J.Neurosci_31_14095
PubMedID: 21976494

Title : In glycine and GABA(A) channels, different subunits contribute asymmetrically to channel conductance via residues in the extracellular domain - Moroni_2011_J.Biol.Chem_286_13414
Author(s) : Moroni M , Meyer JO , Lahmann C , Sivilotti LG
Ref : Journal of Biological Chemistry , 286 :13414 , 2011
Abstract : Moroni_2011_J.Biol.Chem_286_13414
ESTHER : Moroni_2011_J.Biol.Chem_286_13414
PubMedSearch : Moroni_2011_J.Biol.Chem_286_13414
PubMedID: 21343294

Title : Human alpha3beta4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells - Krashia_2010_PLoS.One_5_e13611
Author(s) : Krashia P , Moroni M , Broadbent S , Hofmann G , Kracun S , Beato M , Groot-Kormelink PJ , Sivilotti LG
Ref : PLoS ONE , 5 :e13611 , 2010
Abstract : Krashia_2010_PLoS.One_5_e13611
ESTHER : Krashia_2010_PLoS.One_5_e13611
PubMedSearch : Krashia_2010_PLoS.One_5_e13611
PubMedID: 21049012

Title : What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor - Sivilotti_2010_J.Physiol_588_45
Author(s) : Sivilotti LG
Ref : Journal of Physiology , 588 :45 , 2010
Abstract : Sivilotti_2010_J.Physiol_588_45
ESTHER : Sivilotti_2010_J.Physiol_588_45
PubMedSearch : Sivilotti_2010_J.Physiol_588_45
PubMedID: 19770192

Title : Agonist and blocking actions of choline and tetramethylammonium on human muscle acetylcholine receptors - Lape_2009_J.Physiol_587_5045
Author(s) : Lape R , Krashia P , Colquhoun D , Sivilotti LG
Ref : Journal of Physiology , 587 :5045 , 2009
Abstract : Lape_2009_J.Physiol_587_5045
ESTHER : Lape_2009_J.Physiol_587_5045
PubMedSearch : Lape_2009_J.Physiol_587_5045
PubMedID: 19752108

Title : Intracellular chloride ions regulate the time course of GABA-mediated inhibitory synaptic transmission - Houston_2009_J.Neurosci_29_10416
Author(s) : Houston CM , Bright DP , Sivilotti LG , Beato M , Smart TG
Ref : Journal of Neuroscience , 29 :10416 , 2009
Abstract : Houston_2009_J.Neurosci_29_10416
ESTHER : Houston_2009_J.Neurosci_29_10416
PubMedSearch : Houston_2009_J.Neurosci_29_10416
PubMedID: 19692617

Title : On the nature of partial agonism in the nicotinic receptor superfamily - Lape_2008_Nature_454_722
Author(s) : Lape R , Colquhoun D , Sivilotti LG
Ref : Nature , 454 :722 , 2008
Abstract : Lape_2008_Nature_454_722
ESTHER : Lape_2008_Nature_454_722
PubMedSearch : Lape_2008_Nature_454_722
PubMedID: 18633353

Title : High intracellular chloride slows the decay of glycinergic currents - Pitt_2008_J.Neurosci_28_11454
Author(s) : Pitt SJ , Sivilotti LG , Beato M
Ref : Journal of Neuroscience , 28 :11454 , 2008
Abstract : Pitt_2008_J.Neurosci_28_11454
ESTHER : Pitt_2008_J.Neurosci_28_11454
PubMedSearch : Pitt_2008_J.Neurosci_28_11454
PubMedID: 18987182

Title : The kinetics of inhibition of rat recombinant heteromeric alpha1beta glycine receptors by the low-affinity antagonist SR-95531 - Beato_2007_J.Physiol_580_171
Author(s) : Beato M , Burzomato V , Sivilotti LG
Ref : Journal of Physiology , 580 :171 , 2007
Abstract : Beato_2007_J.Physiol_580_171
ESTHER : Beato_2007_J.Physiol_580_171
PubMedSearch : Beato_2007_J.Physiol_580_171
PubMedID: 17218350

Title : Single-channel properties of glycine receptors of juvenile rat spinal motoneurones in vitro - Beato_2007_J.Physiol_580_497
Author(s) : Beato M , Sivilotti LG
Ref : Journal of Physiology , 580 :497 , 2007
Abstract : Beato_2007_J.Physiol_580_497
ESTHER : Beato_2007_J.Physiol_580_497
PubMedSearch : Beato_2007_J.Physiol_580_497
PubMedID: 17272347

Title : Single-channel study of the spasmodic mutation alpha1A52S in recombinant rat glycine receptors - Plested_2007_J.Physiol_581_51
Author(s) : Plested AJ , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG
Ref : Journal of Physiology , 581 :51 , 2007
Abstract : Plested_2007_J.Physiol_581_51
ESTHER : Plested_2007_J.Physiol_581_51
PubMedSearch : Plested_2007_J.Physiol_581_51
PubMedID: 17331994

Title : Incorporation of the beta3 subunit has a dominant-negative effect on the function of recombinant central-type neuronal nicotinic receptors - Broadbent_2006_Mol.Pharmacol_70_1350
Author(s) : Broadbent S , Groot-Kormelink PJ , Krashia PA , Harkness PC , Millar NS , Beato M , Sivilotti LG
Ref : Molecular Pharmacology , 70 :1350 , 2006
Abstract : Broadbent_2006_Mol.Pharmacol_70_1350
ESTHER : Broadbent_2006_Mol.Pharmacol_70_1350
PubMedSearch : Broadbent_2006_Mol.Pharmacol_70_1350
PubMedID: 16822928

Title : Constraining the expression of nicotinic acetylcholine receptors by using pentameric constructs - Groot-Kormelink_2006_Mol.Pharmacol_69_558
Author(s) : Groot-Kormelink PJ , Broadbent S , Beato M , Sivilotti LG
Ref : Molecular Pharmacology , 69 :558 , 2006
Abstract : Groot-Kormelink_2006_Mol.Pharmacol_69_558
ESTHER : Groot-Kormelink_2006_Mol.Pharmacol_69_558
PubMedSearch : Groot-Kormelink_2006_Mol.Pharmacol_69_558
PubMedID: 16269534

Title : The activation mechanism of alpha1 homomeric glycine receptors - Beato_2004_J.Neurosci_24_895
Author(s) : Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG
Ref : Journal of Neuroscience , 24 :895 , 2004
Abstract : Beato_2004_J.Neurosci_24_895
ESTHER : Beato_2004_J.Neurosci_24_895
PubMedSearch : Beato_2004_J.Neurosci_24_895
PubMedID: 14749434

Title : Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens - Burzomato_2004_J.Neurosci_24_10924
Author(s) : Burzomato V , Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG
Ref : Journal of Neuroscience , 24 :10924 , 2004
Abstract : Burzomato_2004_J.Neurosci_24_10924
ESTHER : Burzomato_2004_J.Neurosci_24_10924
PubMedSearch : Burzomato_2004_J.Neurosci_24_10924
PubMedID: 15574743

Title : Function and structure in glycine receptors and some of their relatives - Colquhoun_2004_Trends.Neurosci_27_337
Author(s) : Colquhoun D , Sivilotti LG
Ref : Trends in Neurosciences , 27 :337 , 2004
Abstract : Colquhoun_2004_Trends.Neurosci_27_337
ESTHER : Colquhoun_2004_Trends.Neurosci_27_337
PubMedSearch : Colquhoun_2004_Trends.Neurosci_27_337
PubMedID: 15165738

Title : Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors - Groot-Kormelink_2004_J.Gen.Physiol_123_697
Author(s) : Groot-Kormelink PJ , Broadbent SD , Boorman JP , Sivilotti LG
Ref : Journal of General Physiology , 123 :697 , 2004
Abstract : Groot-Kormelink_2004_J.Gen.Physiol_123_697
ESTHER : Groot-Kormelink_2004_J.Gen.Physiol_123_697
PubMedSearch : Groot-Kormelink_2004_J.Gen.Physiol_123_697
PubMedID: 15148328

Title : The effects of beta3 subunit incorporation on the pharmacology and single channel properties of oocyte-expressed human alpha3beta4 neuronal nicotinic receptors - Boorman_2003_J.Biol.Chem_278_44033
Author(s) : Boorman JP , Beato M , Groot-Kormelink PJ , Broadbent SD , Sivilotti LG
Ref : Journal of Biological Chemistry , 278 :44033 , 2003
Abstract : Boorman_2003_J.Biol.Chem_278_44033
ESTHER : Boorman_2003_J.Biol.Chem_278_44033
PubMedSearch : Boorman_2003_J.Biol.Chem_278_44033
PubMedID: 12912995

Title : Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation - Burzomato_2003_Receptors.Channels_9_353
Author(s) : Burzomato V , Groot-Kormelink PJ , Sivilotti LG , Beato M
Ref : Receptors Channels , 9 :353 , 2003
Abstract : Burzomato_2003_Receptors.Channels_9_353
ESTHER : Burzomato_2003_Receptors.Channels_9_353
PubMedSearch : Burzomato_2003_Receptors.Channels_9_353
PubMedID: 14698963

Title : Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound - Beato_2002_J.Gen.Physiol_119_443
Author(s) : Beato M , Groot-Kormelink PJ , Colquhoun D , Sivilotti LG
Ref : Journal of General Physiology , 119 :443 , 2002
Abstract : Beato_2002_J.Gen.Physiol_119_443
ESTHER : Beato_2002_J.Gen.Physiol_119_443
PubMedSearch : Beato_2002_J.Gen.Physiol_119_443
PubMedID: 11981023

Title : Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of alpha 1 glycine receptors in HEK293 cells - Groot-Kormelink_2002_J.Neurosci.Methods_113_207
Author(s) : Groot-Kormelink PJ , Beato M , Finotti C , Harvey RJ , Sivilotti LG
Ref : Journal of Neuroscience Methodsods , 113 :207 , 2002
Abstract : Groot-Kormelink_2002_J.Neurosci.Methods_113_207
ESTHER : Groot-Kormelink_2002_J.Neurosci.Methods_113_207
PubMedSearch : Groot-Kormelink_2002_J.Neurosci.Methods_113_207
PubMedID: 11772442

Title : Formation of functional alpha3beta4alpha5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach - Groot-Kormelink_2001_Br.J.Pharmacol_134_789
Author(s) : Groot-Kormelink PJ , Boorman JP , Sivilotti LG
Ref : British Journal of Pharmacology , 134 :789 , 2001
Abstract : Groot-Kormelink_2001_Br.J.Pharmacol_134_789
ESTHER : Groot-Kormelink_2001_Br.J.Pharmacol_134_789
PubMedSearch : Groot-Kormelink_2001_Br.J.Pharmacol_134_789
PubMedID: 11606319

Title : Comparison of Native and Recombinant Neuronal Nicotinic Receptors: Problems of Measurement and Expression -
Author(s) : Sivilotti LG , Colquhoun D , Millar NS
Ref : Handbook of Experimental Pharmacology , 144 :379 , 2000
PubMedID:

Title : Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes - Boorman_2000_J.Physiol_529 Pt 3_565
Author(s) : Boorman JP , Groot-Kormelink PJ , Sivilotti LG
Ref : Journal of Physiology , 529 Pt 3 :565 , 2000
Abstract : Boorman_2000_J.Physiol_529 Pt 3_565
ESTHER : Boorman_2000_J.Physiol_529 Pt 3_565
PubMedSearch : Boorman_2000_J.Physiol_529 Pt 3_565
PubMedID: 11118490

Title : A reporter mutation approach shows incorporation of the orphan subunit beta3 into a functional nicotinic receptor - Groot-Kormelink_1998_J.Biol.Chem_273_15317
Author(s) : Groot-Kormelink PJ , Luyten WH , Colquhoun D , Sivilotti LG
Ref : Journal of Biological Chemistry , 273 :15317 , 1998
Abstract : Groot-Kormelink_1998_J.Biol.Chem_273_15317
ESTHER : Groot-Kormelink_1998_J.Biol.Chem_273_15317
PubMedSearch : Groot-Kormelink_1998_J.Biol.Chem_273_15317
PubMedID: 9624109

Title : Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes - Lewis_1998_J.Physiol_507 ( Pt 1)_25
Author(s) : Lewis TM , Sivilotti LG , Colquhoun D , Gardiner RM , Schoepfer R , Rees M
Ref : Journal of Physiology , 507 ( Pt 1) :25 , 1998
Abstract : Lewis_1998_J.Physiol_507 ( Pt 1)_25
ESTHER : Lewis_1998_J.Physiol_507 ( Pt 1)_25
PubMedSearch : Lewis_1998_J.Physiol_507 ( Pt 1)_25
PubMedID: 9490812

Title : The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type - Lewis_1997_J.Physiol_505 ( Pt 2)_299
Author(s) : Lewis TM , Harkness PC , Sivilotti LG , Colquhoun D , Millar NS
Ref : The Journal of Physiology , 505 ( Pt 2) :299 , 1997
Abstract : Lewis_1997_J.Physiol_505 ( Pt 2)_299
ESTHER : Lewis_1997_J.Physiol_505 ( Pt 2)_299
PubMedSearch : Lewis_1997_J.Physiol_505 ( Pt 2)_299
PubMedID: 9423173

Title : Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour - Sivilotti_1997_J.Physiol_500 ( Pt 1)_123
Author(s) : Sivilotti LG , McNeil DK , Lewis TM , Nassar MA , Schoepfer R , Colquhoun D
Ref : Journal of Physiology , 500 ( Pt 1) :123 , 1997
Abstract : Sivilotti_1997_J.Physiol_500 ( Pt 1)_123
ESTHER : Sivilotti_1997_J.Physiol_500 ( Pt 1)_123
PubMedSearch : Sivilotti_1997_J.Physiol_500 ( Pt 1)_123
PubMedID: 9097938

Title : Morphine selectively depresses the slowest, NMDA-independent component of C-fibre-evoked synaptic activity in the rat spinal cord in vitro - Sivilotti_1995_Eur.J.Neurosci_7_12
Author(s) : Sivilotti LG , Gerber G , Rawat B , Woolf CJ
Ref : European Journal of Neuroscience , 7 :12 , 1995
Abstract : Sivilotti_1995_Eur.J.Neurosci_7_12
ESTHER : Sivilotti_1995_Eur.J.Neurosci_7_12
PubMedSearch : Sivilotti_1995_Eur.J.Neurosci_7_12
PubMedID: 7711929

Title : Acetylcholine receptors: too many channels, too few functions -
Author(s) : Sivilotti LG , Colquhoun D
Ref : Science , 269 :1681 , 1995
PubMedID: 7569892

Title : Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurones following chemosensitive primary afferent activation - Woolf_1994_Pain_58_141
Author(s) : Woolf CJ , Shortland P , Sivilotti LG
Ref : Pain , 58 :141 , 1994
Abstract : Woolf_1994_Pain_58_141
ESTHER : Woolf_1994_Pain_58_141
PubMedSearch : Woolf_1994_Pain_58_141
PubMedID: 7816483

Title : Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes - Covernton_1994_J.Physiol_481 ( Pt 1)_27
Author(s) : Covernton PJ , Kojima H , Sivilotti LG , Gibb AJ , Colquhoun D
Ref : Journal of Physiology , 481 ( Pt 1) :27 , 1994
Abstract : Covernton_1994_J.Physiol_481 ( Pt 1)_27
ESTHER : Covernton_1994_J.Physiol_481 ( Pt 1)_27
PubMedSearch : Covernton_1994_J.Physiol_481 ( Pt 1)_27
PubMedID: 7853248

Title : Small-caliber afferent inputs produce a heterosynaptic facilitation of the synaptic responses evoked by primary afferent A-fibers in the neonatal rat spinal cord in vitro - Thompson_1993_J.Neurophysiol_69_2116
Author(s) : Thompson SW , Woolf CJ , Sivilotti LG
Ref : Journal of Neurophysiology , 69 :2116 , 1993
Abstract : Thompson_1993_J.Neurophysiol_69_2116
ESTHER : Thompson_1993_J.Neurophysiol_69_2116
PubMedSearch : Thompson_1993_J.Neurophysiol_69_2116
PubMedID: 8350135

Title : Rate of rise of the cumulative depolarization evoked by repetitive stimulation of small-caliber afferents is a predictor of action potential windup in rat spinal neurons in vitro - Sivilotti_1993_J.Neurophysiol_69_1621
Author(s) : Sivilotti LG , Thompson SW , Woolf CJ
Ref : Journal of Neurophysiology , 69 :1621 , 1993
Abstract : Sivilotti_1993_J.Neurophysiol_69_1621
ESTHER : Sivilotti_1993_J.Neurophysiol_69_1621
PubMedSearch : Sivilotti_1993_J.Neurophysiol_69_1621
PubMedID: 8389833

Title : Long duration ventral root potentials in the neonatal rat spinal cord in vitro\; the effects of ionotropic and metabotropic excitatory amino acid receptor antagonists - Thompson_1992_Brain.Res_595_87
Author(s) : Thompson SW , Gerber G , Sivilotti LG , Woolf CJ
Ref : Brain Research , 595 :87 , 1992
Abstract : Thompson_1992_Brain.Res_595_87
ESTHER : Thompson_1992_Brain.Res_595_87
PubMedSearch : Thompson_1992_Brain.Res_595_87
PubMedID: 1361412