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| Title : Dual functional antioxidant and butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of novel melatonin-alkylbenzylamine hybrids - Liu_2023_Bioorg.Med.Chem_78_117146 |
| Author(s) : Liu P , Cheng M , Guo J , Cao D , Luo J , Wan Y , Fang Y , Jin Y , Xie SS , Liu J |
| Ref : Bioorganic & Medicinal Chemistry , 78 :117146 , 2023 |
| Abstract : Liu_2023_Bioorg.Med.Chem_78_117146 |
| ESTHER : Liu_2023_Bioorg.Med.Chem_78_117146 |
| PubMedSearch : Liu_2023_Bioorg.Med.Chem_78_117146 |
| PubMedID: 36580744 |
| Title : Design, Synthesis and Biological Evaluation of New 3,4-Dihydro-2(1H)-Quinolinone-Dithiocarbamate Derivatives as Multifunctional Agents for the Treatment of Alzheimer's Disease - Guo_2022_Drug.Des.Devel.Ther_16_1495 |
| Author(s) : Guo J , Xu A , Cheng M , Wan Y , Wang R , Fang Y , Jin Y , Xie SS , Liu J |
| Ref : Drug Des Devel Ther , 16 :1495 , 2022 |
| Abstract : Guo_2022_Drug.Des.Devel.Ther_16_1495 |
| ESTHER : Guo_2022_Drug.Des.Devel.Ther_16_1495 |
| PubMedSearch : Guo_2022_Drug.Des.Devel.Ther_16_1495 |
| PubMedID: 35611357 |
| Title : A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator - Guo_2022_Eur.J.Med.Chem_242_114630 |
| Author(s) : Guo J , Cheng M , Liu P , Cao D , Luo J , Wan Y , Fang Y , Jin Y , Xie SS , Liu J |
| Ref : Eur Journal of Medicinal Chemistry , 242 :114630 , 2022 |
| Abstract : Guo_2022_Eur.J.Med.Chem_242_114630 |
| ESTHER : Guo_2022_Eur.J.Med.Chem_242_114630 |
| PubMedSearch : Guo_2022_Eur.J.Med.Chem_242_114630 |
| PubMedID: 35987018 |
| Title : Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer's disease - Zhang_2021_Eur.J.Med.Chem_213_113154 |
| Author(s) : Zhang Z , Guo J , Cheng M , Zhou W , Wan Y , Wang R , Fang Y , Jin Y , Liu J , Xie SS |
| Ref : Eur Journal of Medicinal Chemistry , 213 :113154 , 2021 |
| Abstract : Zhang_2021_Eur.J.Med.Chem_213_113154 |
| ESTHER : Zhang_2021_Eur.J.Med.Chem_213_113154 |
| PubMedSearch : Zhang_2021_Eur.J.Med.Chem_213_113154 |
| PubMedID: 33476932 |
| Title : Design, synthesis and evaluation of quinolinone derivatives containing dithiocarbamate moiety as multifunctional AChE inhibitors for the treatment of Alzheimer's disease - Fu_2020_J.Enzyme.Inhib.Med.Chem_35_118 |
| Author(s) : Fu J , Bao F , Gu M , Liu J , Zhang Z , Ding J , Xie SS |
| Ref : J Enzyme Inhib Med Chem , 35 :118 , 2020 |
| Abstract : Fu_2020_J.Enzyme.Inhib.Med.Chem_35_118 |
| ESTHER : Fu_2020_J.Enzyme.Inhib.Med.Chem_35_118 |
| PubMedSearch : Fu_2020_J.Enzyme.Inhib.Med.Chem_35_118 |
| PubMedID: 31694418 |
| Title : Design, synthesis and evaluation of novel ferulic acid derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease - Lan_2019_Bioorg.Chem__103413 |
| Author(s) : Lan JS , Zeng RF , Jiang XY , Hou JW , Liu Y , Hu ZH , Li HX , Li Y , Xie SS , Ding Y , Zhang T |
| Ref : Bioorg Chem , :103413 , 2019 |
| Abstract : Lan_2019_Bioorg.Chem__103413 |
| ESTHER : Lan_2019_Bioorg.Chem__103413 |
| PubMedSearch : Lan_2019_Bioorg.Chem__103413 |
| PubMedID: 31791679 |
| Title : Novel chromanone-dithiocarbamate hybrids as multifunctional AChE inhibitors with beta-amyloid anti-aggregation properties for the treatment of Alzheimer's disease - Jiang_2019_Bioorg.Chem_89_103027 |
| Author(s) : Jiang N , Ding J , Liu J , Sun X , Zhang Z , Mo Z , Li X , Yin H , Tang W , Xie SS |
| Ref : Bioorg Chem , 89 :103027 , 2019 |
| Abstract : Jiang_2019_Bioorg.Chem_89_103027 |
| ESTHER : Jiang_2019_Bioorg.Chem_89_103027 |
| PubMedSearch : Jiang_2019_Bioorg.Chem_89_103027 |
| PubMedID: 31176237 |
| Title : Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer's disease: Design, synthesis and biological evaluation - He_2018_Bioorg.Chem_81_512 |
| Author(s) : He Q , Liu J , Lan JS , Ding J , Sun Y , Fang Y , Jiang N , Yang Z , Sun L , Jin Y , Xie SS |
| Ref : Bioorg Chem , 81 :512 , 2018 |
| Abstract : He_2018_Bioorg.Chem_81_512 |
| ESTHER : He_2018_Bioorg.Chem_81_512 |
| PubMedSearch : He_2018_Bioorg.Chem_81_512 |
| PubMedID: 30245233 |
| Title : Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease - Jiang_2018_Eur.J.Med.Chem_146_287 |
| Author(s) : Jiang N , Huang Q , Liu J , Liang N , Li Q , Xie SS |
| Ref : Eur Journal of Medicinal Chemistry , 146 :287 , 2018 |
| Abstract : Jiang_2018_Eur.J.Med.Chem_146_287 |
| ESTHER : Jiang_2018_Eur.J.Med.Chem_146_287 |
| PubMedSearch : Jiang_2018_Eur.J.Med.Chem_146_287 |
| PubMedID: 29407958 |
| Title : Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors - Lan_2017_Eur.J.Med.Chem_133_184 |
| Author(s) : Lan JS , Zhang T , Liu Y , Yang J , Xie SS , Liu J , Miao ZY , Ding Y |
| Ref : Eur Journal of Medicinal Chemistry , 133 :184 , 2017 |
| Abstract : Lan_2017_Eur.J.Med.Chem_133_184 |
| ESTHER : Lan_2017_Eur.J.Med.Chem_133_184 |
| PubMedSearch : Lan_2017_Eur.J.Med.Chem_133_184 |
| PubMedID: 28388521 |
| Title : Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease - Lan_2017_Eur.J.Med.Chem_139_48 |
| Author(s) : Lan JS , Ding Y , Liu Y , Kang P , Hou JW , Zhang XY , Xie SS , Zhang T |
| Ref : Eur Journal of Medicinal Chemistry , 139 :48 , 2017 |
| Abstract : Lan_2017_Eur.J.Med.Chem_139_48 |
| ESTHER : Lan_2017_Eur.J.Med.Chem_139_48 |
| PubMedSearch : Lan_2017_Eur.J.Med.Chem_139_48 |
| PubMedID: 28797883 |
| Title : Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase\/monoamine oxidase inhibitors for the potential application against Alzheimer's disease - Li_2016_J.Enzyme.Inhib.Med.Chem__1 |
| Author(s) : Li F , Wang ZM , Wu JJ , Wang J , Xie SS , Lan JS , Xu W , Kong LY , Wang XB |
| Ref : J Enzyme Inhib Med Chem , :1 , 2016 |
| Abstract : Li_2016_J.Enzyme.Inhib.Med.Chem__1 |
| ESTHER : Li_2016_J.Enzyme.Inhib.Med.Chem__1 |
| PubMedSearch : Li_2016_J.Enzyme.Inhib.Med.Chem__1 |
| PubMedID: 27384289 |
| Title : Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease - Xie_2016_Bioorg.Med.Chem_24_1528 |
| Author(s) : Xie SS , Lan JS , Wang X , Wang ZM , Jiang N , Li F , Wu JJ , Wang J , Kong LY |
| Ref : Bioorganic & Medicinal Chemistry , 24 :1528 , 2016 |
| Abstract : Xie_2016_Bioorg.Med.Chem_24_1528 |
| ESTHER : Xie_2016_Bioorg.Med.Chem_24_1528 |
| PubMedSearch : Xie_2016_Bioorg.Med.Chem_24_1528 |
| PubMedID: 26917219 |
| Title : Multi-target tacrine-coumarin hybrids: Cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease - Xie_2015_Eur.J.Med.Chem_95_153 |
| Author(s) : Xie SS , Wang X , Jiang N , Yu W , Wang KD , Lan JS , Li ZR , Kong LY |
| Ref : Eur Journal of Medicinal Chemistry , 95 :153 , 2015 |
| Abstract : Xie_2015_Eur.J.Med.Chem_95_153 |
| ESTHER : Xie_2015_Eur.J.Med.Chem_95_153 |
| PubMedSearch : Xie_2015_Eur.J.Med.Chem_95_153 |
| PubMedID: 25812965 |
| Title : Multifunctional tacrine-trolox hybrids for the treatment of Alzheimer's disease with cholinergic, antioxidant, neuroprotective and hepatoprotective properties - Xie_2015_Eur.J.Med.Chem_93C_42 |
| Author(s) : Xie SS , Lan JS , Wang XB , Jiang N , Dong G , Li ZR , Wang KD , Guo PP , Kong LY |
| Ref : Eur Journal of Medicinal Chemistry , 93C :42 , 2015 |
| Abstract : Xie_2015_Eur.J.Med.Chem_93C_42 |
| ESTHER : Xie_2015_Eur.J.Med.Chem_93C_42 |
| PubMedSearch : Xie_2015_Eur.J.Med.Chem_93C_42 |
| PubMedID: 25656088 |
| Title : Design, synthesis and biological evaluation of benzylisoquinoline derivatives as multifunctional agents against Alzheimer's disease - Xu_2014_Bioorg.Med.Chem.Lett_24_2368 |
| Author(s) : Xu ZC , Wang XB , Yu WY , Xie SS , Li SY , Kong LY |
| Ref : Bioorganic & Medicinal Chemistry Lett , 24 :2368 , 2014 |
| Abstract : Xu_2014_Bioorg.Med.Chem.Lett_24_2368 |
| ESTHER : Xu_2014_Bioorg.Med.Chem.Lett_24_2368 |
| PubMedSearch : Xu_2014_Bioorg.Med.Chem.Lett_24_2368 |
| PubMedID: 24726809 |
| Title : Design, synthesis and evaluation of novel tacrine-(beta-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease - Lan_2014_Bioorg.Med.Chem_22_6089 |
| Author(s) : Lan JS , Xie SS , Li SY , Pan LF , Wang XB , Kong LY |
| Ref : Bioorganic & Medicinal Chemistry , 22 :6089 , 2014 |
| Abstract : Lan_2014_Bioorg.Med.Chem_22_6089 |
| ESTHER : Lan_2014_Bioorg.Med.Chem_22_6089 |
| PubMedSearch : Lan_2014_Bioorg.Med.Chem_22_6089 |
| PubMedID: 25282654 |
| Title : Multifunctional tacrine-flavonoid hybrids with cholinergic, beta-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease - Li_2013_Eur.J.Med.Chem_69C_632 |
| Author(s) : Li SY , Wang XB , Xie SS , Jiang N , Wang KD , Yao HQ , Sun HB , Kong LY |
| Ref : Eur Journal of Medicinal Chemistry , 69C :632 , 2013 |
| Abstract : Li_2013_Eur.J.Med.Chem_69C_632 |
| ESTHER : Li_2013_Eur.J.Med.Chem_69C_632 |
| PubMedSearch : Li_2013_Eur.J.Med.Chem_69C_632 |
| PubMedID: 24095756 |
| Title : Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease - Xie_2013_Eur.J.Med.Chem_64C_540 |
| Author(s) : Xie SS , Wang XB , Li JY , Yang L , Kong LY |
| Ref : Eur Journal of Medicinal Chemistry , 64C :540 , 2013 |
| Abstract : Xie_2013_Eur.J.Med.Chem_64C_540 |
| ESTHER : Xie_2013_Eur.J.Med.Chem_64C_540 |
| PubMedSearch : Xie_2013_Eur.J.Med.Chem_64C_540 |
| PubMedID: 23685572 |