9acto-q1psf3

Streptomyces tsusimaensis vlm2 thioesterase domain

Comment

only c-term PfamA Thioesterase

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Streptomyces tsusimaensis

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Streptomycetales N E > Streptomycetaceae N E > Streptomyces N E > Streptomyces tsusimaensis N E > cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Streptomycetales N E > Streptomycetaceae N E > Streptomyces N E > Streptomyces tsusimaensis N E > cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Streptomycetales N E > Streptomycetaceae N E > Streptomyces N E > Streptomyces tsusimaensis N E

Molecular evidence

No mutation

6ECB - Streptomyces tsusimaensis vlm2 thioesterase domain wild type structure 1 6ECB - Streptomyces tsusimaensis vlm2 thioesterase domain wild type structure 1 6ECB - Streptomyces tsusimaensis vlm2 thioesterase domain wild type structure 1 6ECC - Streptomyces tsusimaensis vlm2 thioesterase domain wild type structure 2 6ECC - Streptomyces tsusimaensis vlm2 thioesterase domain wild type structure 2 6ECC - Streptomyces tsusimaensis vlm2 thioesterase domain wild type structure 2 6ECD - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a tetradepsipeptide 6ECD - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a tetradepsipeptide 6ECD - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a tetradepsipeptide 6ECE - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group H3 6ECE - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group H3 6ECE - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group H3 6ECF - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group P1 6ECF - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group P1 6ECF - Streptomyces tsusimaensis vlm2 thioesterase with genetically encoded 2,3-diaminopropionic acid bound with a dodecadepsipeptide, space group P1

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

NLYFQGGSST AGDPTAKLVR LNPRGGDGPG IVFAPPAGGT VLGYIELARH LKGFGEIHGV EAPGLGAGET PVYPSFEEMV QFCSDSAAGV AGDGVYIGGH SLGGHIAFYL ATMLLDRGIR PKGLIILDTP PRLGDIPVAD ADLTEEETKV FILAMGIGGM LDQDRDALKD LPYEEAKQLL LDRAKNDPRV SAFLSEDYLD RFLRLQMHQL MYSRDVVLPQ RKLDIPIHVF RTKNHAPEVA RLFSAWENYA AGEVTFVDIP GDHATMLRAP HVSEVAQLLD RHCGLPSDDG PRG

References (6)

Title : Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid - Huguenin-Dezot_2019_Nature_565_112
Author(s) : Huguenin-Dezot N , Alonzo DA , Heberlig GW , Mahesh M , Nguyen DP , Dornan MH , Boddy CN , Schmeing TM , Chin JW
Ref : Nature , 565 :112 , 2019
Abstract :
PubMedSearch : Huguenin-Dezot_2019_Nature_565_112
PubMedID: 30542153
Gene_locus related to this paper: 9acto-q1psf3

Title : Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid - Huguenin-Dezot_2019_Nature_565_112
Author(s) : Huguenin-Dezot N , Alonzo DA , Heberlig GW , Mahesh M , Nguyen DP , Dornan MH , Boddy CN , Schmeing TM , Chin JW
Ref : Nature , 565 :112 , 2019
Abstract :
PubMedSearch : Huguenin-Dezot_2019_Nature_565_112
PubMedID: 30542153
Gene_locus related to this paper: 9acto-q1psf3

Title : Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid - Huguenin-Dezot_2019_Nature_565_112
Author(s) : Huguenin-Dezot N , Alonzo DA , Heberlig GW , Mahesh M , Nguyen DP , Dornan MH , Boddy CN , Schmeing TM , Chin JW
Ref : Nature , 565 :112 , 2019
Abstract :
PubMedSearch : Huguenin-Dezot_2019_Nature_565_112
PubMedID: 30542153
Gene_locus related to this paper: 9acto-q1psf3

Title : Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141 - Cheng_2006_Chembiochem_7_471
Author(s) : Cheng YQ
Ref : Chembiochem , 7 :471 , 2006
Abstract :
PubMedSearch : Cheng_2006_Chembiochem_7_471
PubMedID: 16511823
Gene_locus related to this paper: 9acto-q1psf3 , 9acto-q1psf5

Title : Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141 - Cheng_2006_Chembiochem_7_471
Author(s) : Cheng YQ
Ref : Chembiochem , 7 :471 , 2006
Abstract :
PubMedSearch : Cheng_2006_Chembiochem_7_471
PubMedID: 16511823
Gene_locus related to this paper: 9acto-q1psf3 , 9acto-q1psf5

Title : Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141 - Cheng_2006_Chembiochem_7_471
Author(s) : Cheng YQ
Ref : Chembiochem , 7 :471 , 2006
Abstract :
PubMedSearch : Cheng_2006_Chembiochem_7_471
PubMedID: 16511823
Gene_locus related to this paper: 9acto-q1psf3 , 9acto-q1psf5