Lyngbya majuscula 19L Polyketide synthase
only a little C-terminal 1979-2036 part homologous to ab-hydrolases. || In Gu et al. the sequence is corrected because Q6DNE0 may have been partially replaced with exogenous DNA during construction of the genomic library
Family : 6_AlphaBeta_hydrolase
Block : X
Position in NCBI Life Tree : Lyngbya majuscula 19L
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Cyanobacteria\/Melainabacteria group N E > Cyanobacteria N E > Oscillatoriophycideae N E > Oscillatoriales N E > Oscillatoriaceae N E > Moorea N E > Moorea producens N E > Moorea producens 19L N EMEEKFLEFGG NQICLCSWGS PEHPVVLCIH GILEQGLAWQ EVALPLAAQG YRVVAPDLFG HGRSSHLEMV TSYSSLTFLA QIDRVIQELP DQPLLLVGHS MGAMLATAIA SVRPKKIKEL ILVELPLPAE ESKKESAVNQ LTTCLDYLSS TPQHPIFPDV ATAASRLRQA IPSLSEEFSY ILAQRITQPN QGGVRWSWDA IIRTRSILGL NNLPGGRSQY LEMLKSIQVP TTLVYGDSSK LNRPEDLQQQ KMTMTQAKRV FLSGGHNLHI DAAAALASLI LTS
Title : Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase - Gehret_2011_J.Biol.Chem_286_14445 |
Author(s) : Gehret JJ , Gu L , Gerwick WH , Wipf P , Sherman DH , Smith JL |
Ref : Journal of Biological Chemistry , 286 :14445 , 2011 |
Abstract : |
PubMedSearch : Gehret_2011_J.Biol.Chem_286_14445 |
PubMedID: 21357626 |
Gene_locus related to this paper: 9cyan-d0e8e2 |
Title : Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis - Gu_2009_J.Am.Chem.Soc_131_16033 |
Author(s) : Gu L , Wang B , Kulkarni A , Gehret JJ , Lloyd KR , Gerwick L , Gerwick WH , Wipf P , Hakansson K , Smith JL , Sherman DH |
Ref : Journal of the American Chemical Society , 131 :16033 , 2009 |
Abstract : |
PubMedSearch : Gu_2009_J.Am.Chem.Soc_131_16033 |
PubMedID: 19835378 |
Gene_locus related to this paper: 9cyan-d0e8e2 |
Title : Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula - Chang_2004_J.Nat.Prod_67_1356 |
Author(s) : Chang Z , Sitachitta N , Rossi JV , Roberts MA , Flatt PM , Jia J , Sherman DH , Gerwick WH |
Ref : Journal of Natural Products , 67 :1356 , 2004 |
Abstract : |
PubMedSearch : Chang_2004_J.Nat.Prod_67_1356 |
PubMedID: 15332855 |
Gene_locus related to this paper: 9cyan-d0e8e2 , 9cyan-q6dnd9 |