9viru-g5csv8

Megavirus chiliensis Megavirus courdo7;Megavirus lba ,Putative cholinesterase

Comment

Other strains: Megavirus chiliensis\; Megavirus courdo(7\;11)\; Megavirus lba || Close to acetylcholinesterase but active site serine in GQSAGG, Cysteins not all conserved, HGGA instead of YGGG ... Seems to be an horizontal gene transfer. The genome of Mimivirus is the largest virus genome known 1.2Mb

Relationship

Family : Cholinesterase-like

Block : C

Position in NCBI Life Tree : Megavirus chiliensis

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> Viruses N E > dsDNA viruses, no RNA stage N E > Mimiviridae N E > unclassified Mimiviridae N E > Megavirus chiliensis N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MTNHNIIILL LLGICCIQAT QFTQVNIDNG PIKGVLQYVE GRAIRVFKGI PFAEPPVNNL RWKAPVPYTK KWHKPLNTTE YKPRCPQYVA TGTIPDPRGI SEDCLYTNVW APVPEYHGET FPVMVWIHGG AFISGSPEDF GAGNFSILAV TKRIIIVAAS YRVNAFGFFS SALLGKSQPE ARGVYGLLDQ RLGLKWVKNN IAAFGGKSKD ITIYGQSAGG ISVCLQAVTP LNDLPGEKLF NRVIGSSGYC DILPMTNNSA DAGLVQKLNC TTKECLYALP WQNITNAVGP GFLSFQPTVG INHFLPDQPI SLLAERTNPR NKNFVPDIYM QGFAANEGTF VLYNYFPQTY DNPNTPGFPT QQIADALSIA SGNYSAEFYY NNLAPLYSTE YNPNVTYPGQ GFISRVDDIM ACNTRRNMIY WQRSKKTKAH SWYFDSAPDT RVYPSWTKVF HESDVFYVAR HCDGLWCTNL TCQQDNLGKT MDIYWNSAIR SGSLTPKNQF DNLRDVPVWP QYGKNEVVMH FTAAGENKGP QTSILFSSII SADGDYQYLQ RCETLDKVRA EYYNIPALDP NTYFNTCST

References (1)

Title : Distant Mimivirus relative with a larger genome highlights the fundamental features of Megaviridae - Arslan_2011_Proc.Natl.Acad.Sci.U.S.A_108_17486
Author(s) : Arslan D , Legendre M , Seltzer V , Abergel C , Claverie JM
Ref : Proc Natl Acad Sci U S A , 108 :17486 , 2011
Abstract :
PubMedSearch : Arslan_2011_Proc.Natl.Acad.Sci.U.S.A_108_17486
PubMedID: 21987820
Gene_locus related to this paper: 9viru-g5csv8