byssn-VdtD

Byssochlamys spectabilis (anamorph: Paecilomyces variotii) VdtD Dirigent Protein

Comment

This protein related to lipases is a dirigent protein which controls the stereoselectivity of multicopper oxidase(VdtB)-catalyzed phenol coupling in viriditoxin biosynthesis

Relationship

Family : Fungal_carboxylesterase_lipase

Block : C

Position in NCBI Life Tree : Byssochlamys spectabilis

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Pezizomycotina N E > leotiomyceta N E > Eurotiomycetes N E > Eurotiomycetidae N E > Eurotiales N E > Thermoascaceae N E > Byssochlamys N E > Byssochlamys spectabilis N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MFMTQIVFGI APTLLKTFSH LTALDLWRPS APYVFDPVTS STYLGTIADG VEEFLGIFYG QDTGGSNRFA PPKPYIPSRH SFINASTAGA ACPQPYVPLP ADPYTVLTNV SEDCLSLRIA RPENTKSTAK LPVMVWLYGG GASVGTAYDV SYNPVGLIQQ SVVNGSPVIY VAINYRVNLF GHAFSDALLK SKSTNLAMQD QRLGIEWIKN HISAFGGDPD NITLFGEDEG ATYIALHILS NHEVPFHRAI LQSGAAITHH DVNGNRSARN FAAVAARCNC LSDGDRQVDS QDTVDCLRRV PMEDLVNATF EVAHSVDPVN GFRAFMPAVD GYMIPDEPSN LLSRGQVPAN ISILAGWTRD ESSMSVPTSI RTAADAASFI STQFPLLNAS TIHHFLTSLY PESDFTTNSP SSPEKVTPAW RATSALHRDL TLTCPTIFQA WSLRLSSNCT TPVYLYELRQ SPFATALNNS GVGYLGIVHF SDVPYVFNEL ERTYYITDPE ENKLAQRMSA SWTAFASGAF PLCERSERSL GRWEEAYGGD RVCRDRMPEH VRVKGIGDNG DQDDGDEIGK LMARCGFINR LEY

References (1)

Title : Fungal Dirigent Protein Controls the Stereoselectivity of Multicopper Oxidase-Catalyzed Phenol Coupling in Viriditoxin Biosynthesis - Hu_2019_J.Am.Chem.Soc_141_8068
Author(s) : Hu J , Li H , Chooi YH
Ref : Journal of the American Chemical Society , 141 :8068 , 2019
PubMedID: 31045362
Gene_locus related to this paper: byssn-VdtD , byssp-vdta1