Micromonospora echinospora (Micromonospora purpurea) AB hydrolase-1, member of the Nenestatins gene cluster (nes BGC)
Belongs to the Nenestatins (NENs benzo[b]fluorene-containing atypical angucyclines) biosynthetic gene cluster (nes BGC). Inactivation of the nes5 gene led to the accumulation of five new NEN analogs, and absence of NEN A and NEN B
Family : 6_AlphaBeta_hydrolase
Block : X
Position in NCBI Life Tree : Micromonospora echinospora
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Micromonosporales N E > Micromonosporaceae N E > Micromonospora N E > Micromonospora echinospora N EMRKVVSRDGT TIAYERAGEG PPIVLLNGAF RDHTIFDALV PELAPYCTTF VYDRRGRGQS GDSPVYAVER EIEDLAAVIE EAGGSAVVFA GSCGANLALE AAMAGLAITK LALHEPYFRV DGHPKPPLDA ADALRALVAD GRRGEAAEYF LTVLMGLPPE AISQWRQGPL WATNEANAHT LAYDTAICGD FDVPVERLAA LRTETLVVNS DGTSDWLRAA AQATAKALPN GSGRELPGSW HRVETEILAR VLVEFVKA
| Title : Targeted Inactivation of an alpha\/beta Hydrolase Gene Enables Discovery of Heterodimeric Nenestatins - Wei_2026_Mar.Drugs_24_103 |
| Author(s) : Wei W , Jiang X , Zhu Y , Zhang W , Yang C , Zhang Q , Zhang C |
| Ref : Mar Drugs , 24 :103 , 2026 |
| Abstract : |
| PubMedSearch : Wei_2026_Mar.Drugs_24_103 |
| PubMedID: 41892962 |
| Gene_locus related to this paper: micec-Nes5 |