myca9-b1mg17

Mycobacteroides abscessus (Mycobacterium abscessus) MetA metXA Homoserine O-acetyltransferase

Comment

Other strains: Mycobacteroides abscessus (strain ATCC 19977 \/ DSM 44196 \/ CIP 104536 \/ JCM 13569 \/ NCTC 13031 \/ TMC 1543) (Mycobacterium abscessus)

Relationship

Family : Homoserine_transacetylase

Block : X

Position in NCBI Life Tree : Mycobacteroides abscessus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Corynebacteriales N E > Mycobacteriaceae N E > Mycobacterium chelonae group N E > Mycobacterium abscessus N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MTIEQQLPVP HIALPQGDEI AYVPIGSITL ESGAVIDDVT IAVQSWGELS PRRDNVVFVC HALTADSHVV GPAGPDHITG GWWEGIIGPG AAIDTDHWCA VATNVLGGCR GTTGPTSLAR DGKPWGSRFP EVSVRDQVNA DVAALAQLGI TEVAAVVGGS MGGARALEWA VMHPDAVRAA LVLAVGARAT GDQIGTQSTQ IAAIQTDPDW QGGDYHGSGR SPGKGLNLAR RIAHLTYRGE VELDTRFGND PQVGPDGPED PWADGRYAVQ SYLEHQGNKF VRRFDAGSYV ILTESLNRHD VGRGRGGVEK ALRGCPVPVV VGGITSDRLY PLRLQEELAD LLPGCTGLRV VESVHGHDAF LIEFDAVSEL VRETLALAKA TQAS

References (1)

Title : Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site - Chaton_2019_Sci.Rep_9_20267
Author(s) : Chaton CT , Rodriguez ES , Reed RW , Li J , Kenner CW , Korotkov KV
Ref : Sci Rep , 9 :20267 , 2019
PubMedID: 31889085
Gene_locus related to this paper: myctu-metx , myca9-b1mg17 , mychd-k5b926