mycfo-a0a1a0nu50

Mycolicibacterium fortuitum (Mycobacterium fortuitum) Peptidoglycan-binding protein LysinB_MF

Comment

present in the lysis cassette of the prophage phiE1336 || LysinB_MF is a modular enzyme consisting of an N-terminal peptidoglycan-binding domain (PGBD) linked to the alpha\/beta hydrolase domain. Truncation of PGBD significantly enhances the catalytic activity of LysinB_MF.

Relationship

Family : Lysin_B_C_ter

Block : X

Position in NCBI Life Tree : Mycolicibacterium fortuitum

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Corynebacteriales N E > Mycobacteriaceae N E > Mycobacterium fortuitum complex N E > Mycobacterium fortuitum N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MIIGGAWVGL GLGDVDPEIA RFKSFLLRKF AWVRATALDE SEYFDDTTVA VVIELQRRYG MPQSGIVNYA LKVRCGFITP APAVKPMLFT VCGTGVPWWV GPDADVARAV EDRYRWQPVG YRAAPFPMWP SITEGRDELV RLINLFEGDI NLIGYSQGAV VVGQVWKHDI LPTNGRLHHR LPDVKKVVTF GNPMRELGHY WPDGGGAPAR PTTAGILEDR IEDTPDFWRD YAHAGDIYTD CEMDDEGEYK RAIGKIVMGS NVFGGSDSIL AQVIELGLRP IPEAIAAVKA LIDAGTFFGS QTRDHVNYQT GPAIDFLRS

References (2)

Title : The peptidoglycan-binding domain of a mycobacterial prophage-encoded LysinB reveals diverse approaches for domain conservation in hydrolases - Das_2025_Int.J.Biol.Macromol_327_147435
Author(s) : Das R , Nadar K , Arora R , Bajpai U
Ref : Int J Biol Macromol , 327 :147435 , 2025
Abstract :
PubMedSearch : Das_2025_Int.J.Biol.Macromol_327_147435
PubMedID: 40914364
Gene_locus related to this paper: mycfo-a0a1a0nu50

Title : Unlocking prophage potential: In silico and experimental analysis of a novel Mycobacterium fortuitum LysinB containing a peptidoglycan-binding domain - Das_2024_bioRxiv__
Author(s) : Das R , Nadar K , Arora R , Bajpai U
Ref : bioRxiv , : , 2024
Abstract :
PubMedSearch : Das_2024_bioRxiv__
PubMedID: 38405724
Gene_locus related to this paper: mycfo-a0a1a0nu50