Oryctolagus cuniculus (Rabbit) esterase/n-deacetylase (EC 3.5.1.-), 50k hepatic
(from Uniprot) Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity (By similarity)
Family : Arylacetamide_deacetylase
Block : H
Position in NCBI Life Tree : Oryctolagus cuniculus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Lagomorpha N E > Leporidae N E > Oryctolagus N E > Oryctolagus cuniculus N EGVKTVLLLIV GVLGAYYVYT PLPDNIEEPW RLLWVNAHMK TLTNLALFAE YLGSNIFMNT VKFLTSFQEV PPTSDENVTV TETTFNNVPV RVYVPKRKSK TLRRGLFYIH GGGWCVGSAA LSGYDLLSRR TADRLDVVVV STNYRLAPEY HFPIQFEDVY DALKWFLRQD VLEKYGVDPE RVGVSGDSAG GNLAAAVAQQ LIKDPDVKIK LKTQSLIYPA LQTLDMDLPS YRENAQFPIL SKSFMVRLWS EYFTSDRSLE KAMLLNQHVP VESSHLFKFT NWSSLLPEKF KKGHVYNTPT YGSSELARKY PGFLDVRAAP LLADDAQLRG FPLTYVITCQ YDVLRDDGVM YVTRLRNAGV QVTHNHIEDG FHGALSYNGF KTGYRVEKQY FEWLRENV
| Title : Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase - Frick_2004_J.Biol.Chem_279_31131 |
| Author(s) : Frick C , Atanasov AG , Arnold P , Ozols J , Odermatt A |
| Ref : Journal of Biological Chemistry , 279 :31131 , 2004 |
| Abstract : |
| PubMedSearch : Frick_2004_J.Biol.Chem_279_31131 |
| PubMedID: 15152005 |
| Gene_locus related to this paper: rabit-Q7M370 |
| Title : Targeting proteins to the lumen of endoplasmic reticulum using N-terminal domains of 11beta-hydroxysteroid dehydrogenase and the 50-kDa esterase - Mziaut_1999_J.Biol.Chem_274_14122 |
| Author(s) : Mziaut H , Korza G , Hand AR , Gerard C , Ozols J |
| Ref : Journal of Biological Chemistry , 274 :14122 , 1999 |
| Abstract : |
| PubMedSearch : Mziaut_1999_J.Biol.Chem_274_14122 |
| PubMedID: 10318829 |
| Gene_locus related to this paper: rabit-Q7M370 |
| Title : Determination of lumenal orientation of microsomal 50-kDa esterase\/N-deacetylase - Ozols_1998_Biochemistry_37_10336 |
| Author(s) : Ozols J |
| Ref : Biochemistry , 37 :10336 , 1998 |
| Abstract : |
| PubMedSearch : Ozols_1998_Biochemistry_37_10336 |
| PubMedID: 9665742 |
| Gene_locus related to this paper: rabit-Q7M370 |