(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Eukaryota: NE > Opisthokonta: NE > Metazoa: NE > Eumetazoa: NE > Bilateria: NE > Protostomia: NE > Ecdysozoa: NE > Panarthropoda: NE > Arthropoda: NE > Mandibulata: NE > Pancrustacea: NE > Hexapoda: NE > Insecta: NE > Dicondylia: NE > Pterygota: NE > Neoptera: NE > Holometabola: NE > Hymenoptera: NE > Apocrita: NE > Aculeata: NE > Vespoidea: NE > Formicidae: NE > Ponerinae: NE > Ponerini: NE > Harpegnathos: NE > Harpegnathos saltator: NE
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MAARGQHAIAESVVICSLCLLIARSTFAQQPISAGSRYYNRDGVYVPQDA YGYKTIFYKDRRYGLLDPLDRGPTRAPEDRYLYEHSTPRIPLPGILAGWR KDLQGKERPDSKTFRDRDVIVNTNYGQVQGFKVQLYDNPYSLHRPWNPSV DRVTKDVIVFLGIPYALPPVKEGRFKPPRPNRGWQLIQAIDWGPACPQPS EYTGKTKGVEIVDEDCLYLNIFTPSTDAGVASKYAVMFYIHGGEFTYGAS NLFPAHILAAFYNVVVVSINYRLGALGFLSTGDENSPGNYGILDQAMALR WVYDNIAFFNGNPESITLFGPGAGAASAGLLMVVPRTRELVSKVIAQSGS ALADWAVIMDKYRAQNTSRVYAQMVGCSIESSWKLVQCLKDGRNPFELSN PRFQPHVGMFPWAPVLDINFTIPQDHWYDGWRASDWRFFAETPEESIKAG RYRKDLAYMTGVTTQEAAYIIRNNETLRNNRYVIDSELFDQKVRELVLQY NYTLNPQGVYEAIKYMYTYWPDPMNVTHIRDQYINLLSDFHYVAPNDKMV KLLVEKYVPTYLYVLNTSIESFNLPQWAKVPHDTEHLWLTGAPFMDPEFF PERLKLNRDMWTDSDRNMSHFFMKAYSNFATYGNPTPSQILGLHFDVTRY GQLRYLNINTTLNSSIEINYRQTESAFWSMYLPTVIGYLVPTYPPVTEYW WEPKQPLQIAFWSMSTACLLLLVLSVVCCMLWRNAKRQSDHYYSGDILMV RDDEHSEGIENLTRASKENIYEYRDVPIKTRVPRQNEAKLQERLAQNRKF SSTPSLRSNSNVSLKDMRSEGFVTSSPNGQPKLTKAMSQSALPKAKSRTL LVQGIPQTAV
The organized societies of ants include short-lived worker castes displaying specialized behavior and morphology and long-lived queens dedicated to reproduction. We sequenced and compared the genomes of two socially divergent ant species: Camponotus floridanus and Harpegnathos saltator. Both genomes contained high amounts of CpG, despite the presence of DNA methylation, which in non-Hymenoptera correlates with CpG depletion. Comparison of gene expression in different castes identified up-regulation of telomerase and sirtuin deacetylases in longer-lived H. saltator reproductives, caste-specific expression of microRNAs and SMYD histone methyltransferases, and differential regulation of genes implicated in neuronal function and chemical communication. Our findings provide clues on the molecular differences between castes in these two ants and establish a new experimental model to study epigenetics in aging and behavior.
