Gene_locus Report for: dolma-ppla1

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Hymenoptera: N E > Apocrita: N E > Aculeata: N E > Vespoidea: N E > Vespidae: N E > Vespinae: N E > Dolichovespula: N E > Dolichovespula maculata: N E

Title: Sequence similarity of a hornet (D. maculata) venom allergen phospholipase A1 with mammalian lipases
Soldatova L, Kochoumian L, King TP
Ref: FEBS Letters, 320:145, 1993 : PubMed
Abstract


ESTHER: Soldatova_1993_FEBS.Lett_320_145
PubMedSearch: Soldatova 1993 FEBS.Lett 320 145
PubMedID: 8458431
Gene_locus related to this paper: dolma-ppla1

Abstract

We have determined the sequence of a venom allergen phospholipase A1 from white-faced hornet (Dolichovespula maculata) by cDNA and protein sequencings. This protein of 300 amino acid residues (Dol m I) has no sequence similarity with other known phospholipases. But it has sequence similarity with mammalian lipases; about 40% identity in overlaps of 123 residues. Tests suggest that hornet phospholipase has weak lipase activity. Hornet venom has 3 major allergens, and another hornet allergen antigen 5 (Dol m V) was previously found to have sequence similarity with a mammalian testis protein and a plant leaf protein.