Gene_Locus Report

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Gene_locus Report for: mycle-LPQC

Mycobacterium leprae putative secreted hydrolaseLPQC

Relationship
Family|Esterase_phb
Block| X
Position in NCBI Life Tree|Mycobacterium leprae
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Corynebacteriales: N E > Mycobacteriaceae: N E > Mycobacterium: N E > Mycobacterium leprae: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AL583919, U00012
2 UniProt : Q9CCL5, Q49658
2 Interpro : Q9CCL5, Q49658
2 Pfam : Q9CCL5, Q49658
2 PIRSF : Q9CCL5, Q49658
2 SUPERFAM : Q9CCL5, Q49658
Sequence
Graphical view for this peptide sequence: mycle-LPQC
Colored MSA for Esterase_phb (raw)
MNVARWLASVVLAVCLAGCVGRQVSASSRDQPGTFQFGGLNRTYVLHVPP
GSPVGLVLNLHGGGGTGAGQQGLTDFDAVADLNNLLVAYPDGYDKSWADG
RGASPADRRHVDDVGFLVELAAKLQSDFGVAPGHVFVTGMSNGGFMSNKL
ACDRADMFAAIAPVAGTLGVDVACHPSQPVSVMDAHGTDDPLVPFNGGDV
HGRGGVSHVVSVTNMVEKWRTADGCQGDPSQQELPDVGDGTFVRRFDYTV
CANSAEVVFYKINKGGHTWPGGKQYLPKVVIGSTTCVFDASEVIAQFFLT
HARS
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MNVARWLASVVLAVCLAGCVGRQVSASSRDQPGTFQFGGLNRTYVLHVPP
GSPVGLVLNLHGGGGTGAGQQGLTDFDAVADLNNLLVAYPDGYDKSWADG
RGASPADRRHVDDVGFLVELAAKLQSDFGVAPGHVFVTGMSNGGFMSNKL
ACDRADMFAAIAPVAGTLGVDVACHPSQPVSVMDAHGTDDPLVPFNGGDV
HGRGGVSHVVSVTNMVEKWRTADGCQGDPSQQELPDVGDGTFVRRFDYTV
CANSAEVVFYKINKGGHTWPGGKQYLPKVVIGSTTCVFDASEVIAQFFLT
HARS


References
    Title: Massive gene decay in the leprosy bacillus
    Cole ST, Eiglmeier K, Parkhill J, James KD, Thomson NR, Wheeler PR, Honore N, Garnier T, Churcher C and Barrell BG <34 more author(s)>
    Ref: Nature, 409:1007, 2001 : PubMed

            

    Title: Genomic organization of the mycobacterial sigma gene cluster
    Doukhan L, Predich M, Nair G, Dussurget O, Mandic-Mulec I, Cole ST, Smith DR, Smith I
    Ref: Gene, 165:67, 1995 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
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