Gene_Locus Report

Biblio print

Add to basket

Go to basket

Tree Display

AceDB Schema

XML Display

Feedback

Gene_locus Report for: mycle-lipG

Mycobacterium leprae (strains TN; Br4923) ML1899 lipG

Relationship
Family|Aclacinomycin-methylesterase_RdmC
Block| X
Position in NCBI Life Tree|Mycobacterium leprae
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Corynebacteriales: N E > Mycobacteriaceae: N E > Mycobacterium: N E > Mycobacterium leprae: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
>3 Genbank links 3 more: AL583923, Z92772, FM211192
1 UniProt : Q9CBK5
1 Ncbi-nid : 13093428
1 Ncbi-pid : 13093568
1 UniProt : Q9CBK5
1 Interpro : Q9CBK5
1 Prodom : Q9CBK5
1 Pfam : Q9CBK5
1 PIRSF : Q9CBK5
1 SUPERFAM : Q9CBK5
Sequence
Graphical view for this peptide sequence: mycle-lipG
Colored MSA for Aclacinomycin-methylesterase_RdmC (raw)
MEVRSGYATSGDLKLYYEDMGNVDDPPVLLIMGLGAQLVLWRTAFCEKLV
AQGLRVVRYDNRDVGLSSRTDSTEQPCPSQPLTARLIRFWLGQRNACAYT
LEDMTDDAVALLDHLSIERAHIVGASMGGMIAQIFAARFPTRTRSLAVFF
SSNNRPFLPPPAPRALLALLTGPPTGSRRDVVVDNVVRVTKITGSPLYRM
PEEQVRTNAAEIYDRSFYPLGVSRQFSAILGSGSLLHYNQRIIAPTVVIH
GRADKLVRPSSGRAVARAITGARLVLFDGMGHDLPQQLWDQAVGVLMSNF
AKAS
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MEVRSGYATSGDLKLYYEDMGNVDDPPVLLIMGLGAQLVLWRTAFCEKLV
AQGLRVVRYDNRDVGLSSRTDSTEQPCPSQPLTARLIRFWLGQRNACAYT
LEDMTDDAVALLDHLSIERAHIVGASMGGMIAQIFAARFPTRTRSLAVFF
SSNNRPFLPPPAPRALLALLTGPPTGSRRDVVVDNVVRVTKITGSPLYRM
PEEQVRTNAAEIYDRSFYPLGVSRQFSAILGSGSLLHYNQRIIAPTVVIH
GRADKLVRPSSGRAVARAITGARLVLFDGMGHDLPQQLWDQAVGVLMSNF
AKAS


References
    Title: Molecular characterization and immunogenic function of ML1899 (LipG) of Mycobacterium leprae
    Rastogi R, Kaur G, Maan P, Bhatnagar A, Narang T, Dogra S, Kaur J
    Ref: J Med Microbiol, 68:1629, 2019 : PubMed

            

    Title: Comparative genomic and phylogeographic analysis of Mycobacterium leprae
    Monot M, Honore N, Garnier T, Zidane N, Sherafi D, Paniz-Mondolfi A, Matsuoka M, Taylor GM, Donoghue HD and Cole ST <21 more author(s)>
    Ref: Nat Genet, 41:1282, 2009 : PubMed

            

    Title: Massive gene decay in the leprosy bacillus
    Cole ST, Eiglmeier K, Parkhill J, James KD, Thomson NR, Wheeler PR, Honore N, Garnier T, Churcher C and Barrell BG <34 more author(s)>
    Ref: Nature, 409:1007, 2001 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer