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Gene_locus Report for: papan-lcat

Papio anubis lecithin cholesterol acyltransferase

Relationship
Family|PC-sterol_acyltransferase
Block| L
Position in NCBI Life Tree|Papio anubis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Primates: N E > Haplorrhini: N E > Simiiformes: N E > Catarrhini: N E > Cercopithecoidea: N E > Cercopithecidae: N E > Cercopithecinae: N E > Papio: N E > Papio anubis: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : L08633
1 UniProt : Q08758
1 Ncbi-nid : 176591
1 Ncbi-pid : 176592
1 UniProt : Q08758
1 Interpro : Q08758
1 Prodom : Q08758
1 Pfam : Q08758
1 PIRSF : Q08758
1 SUPERFAM : Q08758
Sequence
Graphical view for this peptide sequence: papan-lcat
Colored MSA for PC-sterol_acyltransferase (raw)
MGPPGSPWQWVPLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVI
LVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWI
DNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQ
NLVNNGYVRDETVRAAPYDWRLEPGQQEEYYHKLAGLVEEMHAAYGKPVF
LIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASG
DNQGIPIMSSIKLKEEQRITTTSPWMFPSRLAWPEDHVFISTPSFNYTGR
DFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYI
YDHGFPYTDPVDVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLRGIQ
HLNMVFSNQTLEHINAILLGAYRQGPPASLTASPEPPPPE
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MGPPGSPWQWVPLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVI
LVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWI
DNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQ
NLVNNGYVRDETVRAAPYDWRLEPGQQEEYYHKLAGLVEEMHAAYGKPVF
LIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASG
DNQGIPIMSSIKLKEEQRITTTSPWMFPSRLAWPEDHVFISTPSFNYTGR
DFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYI
YDHGFPYTDPVDVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLRGIQ
HLNMVFSNQTLEHINAILLGAYRQGPPASLTASPEPPPPE


Reference
    Title: Baboon lecithin colesterol acyltransferase (LCAT): cDNA sequences of two alleles, evolution, and gene expression
    Hixson JE, Driscoll DM, Birnbaum S, Britten ML
    Ref: Gene, 128:295, 1993 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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