Gene_Locus Report

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Gene_locus Report for: spaau-a0a023i9d7

Sparus aurata (Gilthead sea bream). Bile salt-activated lipase

Relationship
Family|Cholesterol_esterase
Block| C
Position in NCBI Life Tree|Sparus aurata
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Actinopterygii: N E > Actinopteri: N E > Neopterygii: N E > Teleostei: N E > Osteoglossocephalai: N E > Clupeocephala: N E > Euteleosteomorpha: N E > Neoteleostei: N E > Eurypterygia: N E > Ctenosquamata: N E > Acanthomorphata: N E > Euacanthomorphacea: N E > Percomorphaceae: N E > Eupercaria: N E > Spariformes: N E > Sparidae: N E > Sparus: N E > Sparus aurata: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : JX975714
1 UniProt : A0A023I9D7
2 UniProt : A0A023I9D7, A0A0N9BEB3
2 Interpro : A0A023I9D7, A0A0N9BEB3
2 Prodom : A0A023I9D7, A0A0N9BEB3
2 Pfam : A0A023I9D7, A0A0N9BEB3
2 PIRSF : A0A023I9D7, A0A0N9BEB3
2 SUPERFAM : A0A023I9D7, A0A0N9BEB3
Sequence
Graphical view for this peptide sequence: spaau-a0a023i9d7
Colored MSA for Cholesterol_esterase (raw)
MAKLGILIAVAVFLETVSATSLGVVYTEGGMVEGKNIRLGFRRHMDVFKG
IPFADMPGRFEKPKRHPGWDGVLKTTEYRPRCLQVNMLMSDTRGSEDCLY
LNVWVPHGSDVSTGLPVMVWIYGGGFLAGGSMGANFLDNYLYDGQEIADR
GDVIVVTLGYRVGTLGFLSTGDSGIPGNYGLWDQHTAIAWVHRNIRSFGG
DPDNVTIFGESAGGASVSFQTLTPLNKGLFKRAISQSGVAVCPWAINHNP
RRLAEEIALKVGCPTGETMASCLKMTDPALLTLAGSLSLTSSPDDPILNN
LALSPVIDGDFVPDEPHNLFHNVADIDYMAGVNDMDGHLFTGFDVPSINS
PFLDTRIEDMKRLLASYTKEKGKNGLDNAYSTYTSPWGTNPSQETIKKTV
VAIGTDYIFLVPTQAALYLHASNATTGRTYSYLFSEPNRMGGIARPYPSW
MGADHADDLQYMFGKPFSSPLGYWPRHRDVSRYMIAYWTNFAKTGDPNKG
LSVPATWPKFTSSGHQFLEINSDMNKNYVKQKMRLRYVHFWTSILPSLPT
VISE
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MAKLGILIAVAVFLETVSATSLGVVYTEGGMVEGKNIRLGFRRHMDVFKG
IPFADMPGRFEKPKRHPGWDGVLKTTEYRPRCLQVNMLMSDTRGSEDCLY
LNVWVPHGSDVSTGLPVMVWIYGGGFLAGGSMGANFLDNYLYDGQEIADR
GDVIVVTLGYRVGTLGFLSTGDSGIPGNYGLWDQHTAIAWVHRNIRSFGG
DPDNVTIFGESAGGASVSFQTLTPLNKGLFKRAISQSGVAVCPWAINHNP
RRLAEEIALKVGCPTGETMASCLKMTDPALLTLAGSLSLTSSPDDPILNN
LALSPVIDGDFVPDEPHNLFHNVADIDYMAGVNDMDGHLFTGFDVPSINS
PFLDTRIEDMKRLLASYTKEKGKNGLDNAYSTYTSPWGTNPSQETIKKTV
VAIGTDYIFLVPTQAALYLHASNATTGRTYSYLFSEPNRMGGIARPYPSW
MGADHADDLQYMFGKPFSSPLGYWPRHRDVSRYMIAYWTNFAKTGDPNKG
LSVPATWPKFTSSGHQFLEINSDMNKNYVKQKMRLRYVHFWTSILPSLPT
VISE


Reference
    Title: Wide-gene expression analysis of lipid-relevant genes in nutritionally challenged gilthead sea bream (Sparus aurata)
    Benedito-Palos L, Ballester-Lozano G, Perez-Sanchez J
    Ref: Gene, 547:34, 2014 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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