1-Oleoyl-Lysophosphatidic-Acid
substrate of the C1.5.1: Epoxide Hydrolase Phosphatase Like n-terminal part (not a/b hydrolase) of EPHX2 full length and inhibitor of the c-term epoxide hydrolase part. Also product of hydrolysis by LIPH
General
Type :
Chemical_Nomenclature : [(2R)-2-hydroxy-3-phosphonooxypropyl] (Z)-octadec-9-enoate
Canonical SMILES : CCCCCCCC\/C=CCCCCCCCC(=O)OC[C@H](COP(=O)(O)O)O
InChI : InChI=1S\/C21H41O7P\/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26\/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)\/b10-9-\/t20-\/m1\/s1
InChIKey : WRGQSWVCFNIUNZ-GDCKJWNLSA-N
Other name(s) : 1-Oleoyl Lysophosphatidic Acid || 1-Oleoyl-sn-glycerol 3-phosphate || PA(18:1\/0:0) || 18:1 LPA || CHEBI:62837 || LysoPA(18:1) || CHEMBL117021 || LysoPA(18:1w9\/0:0) || LPA(18:1n9\/0:0) || LPA(18:1w9\/0:0)
MW : 436.5
Formula : C21H41O7P
CAS_number : 65528-98-5
PubChem : 5311263
UniChem : WRGQSWVCFNIUNZ-GDCKJWNLSA-N
Target
Families : 1-Oleoyl-Lysophosphatidic-Acid ligand of proteins in family
Epoxide_hydrolase
Protein :
human-EPHX2
References (1)
| Title : Intradomain Allosteric Regulation of Soluble Epoxide Hydrolase by Its Substrates - Matsumura_2024_Int.J.Mol.Sci_25_13496 |
| Author(s) : Matsumura S , Shida A , Tsuchii M , Wada M , Charneau J , Tsuji M , Hasumi K , Suzuki E |
| Ref : Int J Mol Sci , 25 :13496 , 2024 |
| Abstract : |
| PubMedSearch : Matsumura_2024_Int.J.Mol.Sci_25_13496 |
| PubMedID: 39769258 |