4-Mercuriphenylsulfonate

Compounds inhibiting cysteine - dependant enzymes, so not really inhibitors of serine hydrolases, but used as tools whene active serine is mutated to cysteins

General

Type : Sulfur Compound

Chemical_Nomenclature : (4-sulfophenyl)mercury

Canonical SMILES : C1=CC(=CC=C1S(=O)(=O)O)[Hg]

InChI : InChI=1S\/C6H5O3S.Hg\/c7-10(8,9)6-4-2-1-3-5-6\;\/h2-5H,(H,7,8,9)\;

InChIKey : KQAOIKIZSJJTII-UHFFFAOYSA-N

Other name(s) : 4-Mercuriphenylsulfonate  ||  Para-mercury-benzensulfonic acid  ||  P-mercuribenzenesulfonic acid  ||  PMBS


MW : 357.75

Formula : C6H5HgO3S

CAS_number : 17014-79-8

PubChem : 65258

UniChem : KQAOIKIZSJJTII-UHFFFAOYSA-N

Target

Families : 4-Mercuriphenylsulfonate ligand of proteins in family
Cutinase

Structure :
1XZC

Protein :
fusso-cutas

References (2)

Title : Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants - Longhi_1996_Proteins_26_442
Author(s) : Longhi S , Nicolas A , Creveld L , Egmond M , Verrips CT , de Vlieg J , Martinez C , Cambillau C
Ref : Proteins , 26 :442 , 1996
Abstract :
PubMedSearch : Longhi_1996_Proteins_26_442
PubMedID: 8990497
Gene_locus related to this paper: fusso-cutas

Title : Engineering cysteine mutants to obtain crystallographic phases with a cutinase from Fusarium solani pisi - Martinez_1993_Protein.Eng_6_157
Author(s) : Martinez C , de Geus P , Stanssens P , Lauwereys M , Cambillau C
Ref : Protein Engineering , 6 :157 , 1993
Abstract :
PubMedSearch : Martinez_1993_Protein.Eng_6_157
PubMedID: 8475042
Gene_locus related to this paper: fusso-cutas