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Sulfonyl

General

Sulfonyl groups with the general formula RS(=O)2R, where there are two double bonds between the sulfur and oxygen. Sulfonamide are included in another. Building block for many inhibitors of enzymes
Inhibitor Main targeted enzyme families Type Structure
MTDZ ACHE Sulfur Compound Thiadiazol Sulfonyl
JCP678 A85-EsteraseD-FGH Carbamate Sulfur Compound Sulfonyl
SCHEMBL15589912 Lipoprotein_Lipase Benzothiazol Sulfur Compound Thiazolidine Morpholine Oxadiazol Sulfonyl
LIPG-inhib-Compound32 Lipoprotein_Lipase Pyridine Benzothiazol Sulfur Compound Sulfonyl Cyclopropyl
LK864 Epoxide_hydrolase Azaspiro Sulfur Compound Sulfonyl Urea derivative Trifluoro
P9-benzothiadiazole Haloalkane_dehalogenase-HLD2 Sulfur Compound Fluorescent Probe Thiadiazol Sulfonyl
CHEMBL3087813 ACHE Sulfur Compound Sulfonamide Sulfonyl Benzenesulfonamide
CHEMBL469792 Epoxide_hydrolase Piperidine Sulfur Compound Carboxamide Sulfonyl
34N Epoxide_hydrolase Cyanide Sulfur Compound Sulfonyl
Piperidine-fused-benzimidazole-25 DPP4N_Peptidase_S9 Trifluoro Piperidine Sulfur Compound Imidazole Benzimidazole Sulfonyl
Flouroolefin-2 DPP4N_Peptidase_S9 Sulfur Compound Cyclopropyl Oxadiazol Sulfonyl
5ALH-4UA Epoxide_hydrolase Sulfonamide Carboxamide Sulfur Compound Piperidine Sulfonyl
5ALZ-XQ9 Epoxide_hydrolase Urea derivative Adamantyl Piperidine Sulfur Compound Sulfonyl Sulfonamide
3TP DPP4N_Peptidase_S9 Pyrrolidine Sulfur Compound Oxadiazol Sulfonyl
AEBSF S9N_PREPL_Peptidase_S9 5_AlphaBeta_hydrolase DPP4N_Peptidase_S9 Tiancimycin-TnmK-Tripeptidase-HIP Sulfur Compound Sulfonyl
OTFPdOHSO2 Juvenile_hormone_esterase Trifluoro Sulfur Compound Sulfonyl Halo ketone
1-dodecanesulfonyl-chloride Fungal_carboxylesterase_lipase Sulfur Compound Sulfonyl
1-hexadecanesulfonyl-chloride Hormone-sensitive_lipase_like Bacterial_lip_FamI.5 Fungal_carboxylesterase_lipase Palmitoyl-protein_thioesterase Sulfur Compound Sulfonyl
AM3506 Monoglyceridelipase_lysophospholip FAAH inhibitor Sulfur Compound Sulfonyl
64D Monoglyceridelipase_lysophospholip Piperidine PET probe Sulfonyl Sulfur Compound
DSF LYsophospholipase_carboxylesterase Acidic_Lipase Sulfur Compound Sulfonyl NTE inhibitor Not A\/B H target Lipase inhibitor
Benzenesulfonyl-fluoride ACHE Sulfur Compound Sulfonyl
MSF ACHE Sulfur Compound Sulfonyl
PMSF BCHE ACHE LYsophospholipase_carboxylesterase GTSAGmotif Polyesterase-lipase-cutinase Hormone-sensitive_lipase_like RsbQ-like CarbLipBact_2 Thioesterase Dienelactone_hydrolase Acetyl-esterase_deacetylase Peptidase_S37 Peptidase_S15 Lactobacillus_peptidase Cocaine_esterase BioH Bacterial_lip_FamI.5 Bacterial_lip_FamI.1 PolyAspartate-hydrolase Cutinase FAE-Bacterial-promiscuous ABHD10 S9N_PREPL_Peptidase_S9 PE-PPE Kynurenine-formamidase DPP4N_Peptidase_S9 Pectinacetylesterase-Notum Monoglyceridelipase_lysophospholip CarbLipBact_1 Acetyl_esterase Duf_1100-S Sulfur Compound Sulfonyl
OSF Monoglyceridelipase_lysophospholip Sulfur Compound NTE inhibitor Not A\/B H target Sulfonyl
HDSF Palmitoyl-protein_thioesterase Sulfur Compound Sulfonyl