Amylovis-201
General
Type : Sulfur Compound, Naphthalen
Chemical_Nomenclature : methyl N-[2-[[4-(naphthalen-1-ylamino)-4-oxobutanoyl]amino]ethyl]carbamodithioate
Canonical SMILES : CSC(=S)NCCNC(=O)CCC(=O)NC1=CC=CC2=CC=CC=C21
InChI : InChI=1S\/C18H21N3O2S2\/c1-25-18(24)20-12-11-19-16(22)9-10-17(23)21-15-8-4-6-13-5-2-3-7-14(13)15\/h2-8H,9-12H2,1H3,(H,19,22)(H,20,24)(H,21,23)
InChIKey : BYBDSIFKCBXSEB-UHFFFAOYSA-N
Other name(s) : CHEMBL4798103
MW : 375.5
Formula : C18H21N3O2S2
CAS_number :
PubChem : 77461259
UniChem : BYBDSIFKCBXSEB-UHFFFAOYSA-N
Target
References (2)
| Title : Amylovis-201 is a new dual-target ligand, acting as an anti-amyloidogenic compound and a potent agonist of the s (1) chaperone protein - Garcia-Pupo_2024_Acta.Pharm.Sin.B_14_4345 |
| Author(s) : Garcia-Pupo L , Crouzier L , Bencomo-Martinez A , Meunier J , Morilleau A , Delprat B , Carrazana MS , Menendez Soto Del Valle R , Maurice T , Rodriguez-Tanty C |
| Ref : Acta Pharm Sin B , 14 :4345 , 2024 |
| Abstract : |
| PubMedSearch : Garcia-Pupo_2024_Acta.Pharm.Sin.B_14_4345 |
| PubMedID: 39525570 |
| Title : Amylovis-201 enhances physiological memory formation and rescues memory and hippocampal cell loss in a streptozotocin-induced Alzheimer's disease animal model - Merceron-Martinez_2024_Brain.Res_1831_148848 |
| Author(s) : Merceron-Martinez D , Alacan Ricardo L , Bejerano Pina A , Orama Rojo N , Exposito Seco A , Vega Hurtado Y , Estupinan Dias B , Fernandez I , Garcia Pupo L , Sablon Carrazana M , Rodriguez-Tanty C , Menendez Soto Del Valle R , Almaguer-Melian W |
| Ref : Brain Research , 1831 :148848 , 2024 |
| Abstract : |
| PubMedSearch : Merceron-Martinez_2024_Brain.Res_1831_148848 |
| PubMedID: 38432261 |