| Title : Access to novel potent pleiotropic prodrugs, targeting both butyrylcholinesterase and serotonin reuptake, with anti-amnesic activities in Alzheimer's disease model - Travers-Lesage_2026_Eur.J.Med.Chem_307_118670 |
| Author(s) : Travers-Lesage V , Crouzier L , Antonijevic M , Wang A , Toublet FX , Davis A , Modeste F , Brazzolotto X , Nachon F , Since M , Maurice T , Rochais C , Dallemagne P |
| Ref : Eur Journal of Medicinal Chemistry , 307 :118670 , 2026 |
| Abstract : |
| PubMedSearch : Travers-Lesage_2026_Eur.J.Med.Chem_307_118670 |
| PubMedID: 41702369 |
| Title : A Dual Approach To Combat Alzheimer's Disease through Concomitant hBChE Inhibition and S1R Activation - Reichau_2026_ACS.Chem.Neurosci__ |
| Author(s) : Reichau K , Crouzier L , Poeta E , Gehrig T , Schaller E , Zvejniece L , Meunier J , Sotriffer C , Monti B , Maurice T , Decker M |
| Ref : ACS Chem Neurosci , : , 2026 |
| Abstract : |
| PubMedSearch : Reichau_2026_ACS.Chem.Neurosci__ |
| PubMedID: 41593428 |
| Title : Targeting Neuroinflammation by Activation of the Sigma-1 Receptor (S1R) and Inhibition of Butyrylcholinesterase (hBChE) Leads to Highly Potent Anti-Amnesic Compounds in an Alzheimers Disease Mouse Model - Reichau_2026_J.Med.Chem_305_118486 |
| Author(s) : Reichau K , Crouzier L , Gehrig T , Flake A , Schaller E , Meunier J , Bertrand-Gaday C , Chatonnet A , Zvejniece L , Sotriffer C , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 305 :118486 , 2025 |
| Abstract : |
| PubMedSearch : Reichau_2026_J.Med.Chem_305_118486 |
| PubMedID: 41547241 |
| Title : Amylovis-201 is a new dual-target ligand, acting as an anti-amyloidogenic compound and a potent agonist of the s (1) chaperone protein - Garcia-Pupo_2024_Acta.Pharm.Sin.B_14_4345 |
| Author(s) : Garcia-Pupo L , Crouzier L , Bencomo-Martinez A , Meunier J , Morilleau A , Delprat B , Carrazana MS , Menendez Soto Del Valle R , Maurice T , Rodriguez-Tanty C |
| Ref : Acta Pharm Sin B , 14 :4345 , 2024 |
| Abstract : |
| PubMedSearch : Garcia-Pupo_2024_Acta.Pharm.Sin.B_14_4345 |
| PubMedID: 39525570 |
| Title : The selective butyrylcholinesterase inhibitor UW-MD-95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease - Carles_2024_CNS.Neurosci.Ther_30_e14814 |
| Author(s) : Carles A , Hoffmann M , Scheiner M , Crouzier L , Bertrand-Gaday C , Chatonnet A , Decker M , Maurice T |
| Ref : CNS Neurosci Ther , 30 :e14814 , 2024 |
| Abstract : |
| PubMedSearch : Carles_2024_CNS.Neurosci.Ther_30_e14814 |
| PubMedID: 38887858 |